Medical Assistant Jobs in South Dakota

Medical Assistant jobs in South Dakota are open across Rapid City, Sioux Falls, and Sd and other South Dakota metros, with employers like Sanford Health, Monument Health, and Sioux Center Health hiring at every experience level. Find a role that fits below and apply directly.

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Overview

Open roles58+
Top employerSanford Health
Top cityRapid City, SD
Cities hiring11
Work type100% On-site
Top industryHealthcare

Showing 5 of 58+ Medical Assistant jobs

Monument Health
LPN or Medical Assistant
We won't show you this job again
Monument Health
New 1h ago
LPN or Medical Assistant
Monument Health
Rapid City, South Dakota
Nursing
Clinical Support
Healthcare Administration
Medical Assistant
Patient Services & Wellbeing
On-Site
High School

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Sanford Health
Medical Assistant
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Sanford Health
Added 2d ago
Medical Assistant
Sanford Health
Aberdeen, South Dakota
Nursing
Clinical Support
Healthcare Administration
Medical Assistant
Patient Services & Wellbeing
$19 - $25/hr
On-Site
Other
10,000+

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Monument Health
Clinical Assistant or Medical Assistant
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Monument Health
Added 5d ago
Clinical Assistant or Medical Assistant
Monument Health
Rapid City, South Dakota
Nursing
Clinical Support
Healthcare Administration
Medical Assistant
Patient Services & Wellbeing
$16 - $23/hr
On-Site
High School

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Sanford Health
Medical Assistant
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Sanford Health
Added 5d ago
Medical Assistant
Sanford Health
Rapid City, South Dakota
Nursing
Clinical Support
Healthcare Administration
Medical Assistant
Patient Services & Wellbeing
$19 - $25/hr
On-Site
None
10,000+

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Monument Health
Medical Assistant or LPN
We won't show you this job again
Monument Health
Added 1w ago
Medical Assistant or LPN
Monument Health
Rapid City, South Dakota
Nursing
Clinical Support
Healthcare Administration
Medical Assistant
Patient Services & Wellbeing
$20 - $28/hr
On-Site
High School

Have you applied for this role?

See All 58 Medical Assistant Jobs in South Dakota

Find roles in South Dakota that match your experience and apply in just a few clicks.

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Medical Assistant Jobs by City in South Dakota

Where South Dakota roles are concentrated, by current openings.

Rapid City
23 jobs
Sioux Falls
15 jobs
Sd
5 jobs
Huron
4 jobs
Aberdeen
3 jobs
Custer
2 jobs
Webster
2 jobs
Belle Fourche
1 jobs
Freeman
1 jobs

Medical Assistant Job Market in South Dakota

A snapshot from current South Dakota openings, updated as new roles post.

Who's Hiring

  • Sanford Health
    Sanford Health22
  • Monument Health
    Monument Health15
  • Sioux Center Health
    Sioux Center Health10
  • Sanford Bismarck
    Sanford Bismarck7
  • Huron Regional Medical Center
    Huron Regional Medical Center4

Top Industries Hiring

  • Healthcare & Medical Services58
  • Non-Profit & Social Services5

What South Dakota Employers Look For

The qualifications that appear most often in medical assistant jobs across South Dakota.

  • Active CMA, RMA, or CCMA certification from an accredited program
  • Proficiency with an electronic health record system such as Epic or Athenahealth
  • Demonstrated clinical skills including phlebotomy, injections, and vital signs
  • High school diploma or GED plus completion of an accredited medical assistant program
  • Current CPR and Basic Life Support certification
  • One or more years of clinical or ambulatory care experience in a patient-facing role

Medical Assistant Jobs in South Dakota: Frequently Asked Questions

How many medical assistant jobs are there in South Dakota?

There are 58+ medical assistant openings in South Dakota on Migrate Mate as of June 2026, with the most roles in Rapid City, Sioux Falls, and Sd. New positions post regularly as employers across South Dakota hire.

How much do medical assistants make in South Dakota?

Medical assistants in South Dakota earn a median of about $41,870 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $35,980 for the lowest 10% to over $48,960 for the top 10%. Pay rises with experience, specialty, and employer.

Which South Dakota cities have the most medical assistant jobs?

Rapid City, Sioux Falls, and Sd have the most medical assistant openings in South Dakota right now, with additional roles spread across smaller metros statewide.

Which companies hire medical assistants in South Dakota?

Employers hiring medical assistants in South Dakota include Sanford Health, Monument Health, and Sioux Center Health, based on current listings on Migrate Mate as of June 2026.

Are there remote medical assistant jobs in South Dakota?

Yes. About 0% of medical assistant openings tied to South Dakota are remote or hybrid as of June 2026. The rest are on-site roles based in South Dakota metros.

How do I apply for medical assistant jobs in South Dakota?

You can apply to medical assistant jobs in South Dakota directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred South Dakota location, then apply to each one that fits.

See All 58 Medical Assistant Jobs in South Dakota

Find roles in South Dakota that match your experience and apply in just a few clicks.

Find Medical Assistant Jobs