NP Jobs in South Dakota

NP jobs in South Dakota are concentrated in primary care, rural health, and behavioral health, with demand running from newly licensed graduates through experienced independent practitioners. Sioux Falls, Rapid City, and Aberdeen are the largest hiring markets, anchored by systems such as Sanford Health, Avera Health, and Monument Health. The most in-demand specialties are family practice, psychiatric-mental health, and acute care, reflecting the state's persistent rural access gaps and growing behavioral health needs. See the openings below and apply to the ones that match your experience.

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Overview

Open roles18
Top employerAvera Health
Top citySioux Falls, SD
Cities hiring7
Work type67% Remote
Top credentialDoctoral degree

Showing 5 of 18+ NP jobs

Sanford Health
APP - Nurse Practitioner or Physician Assistant | Occupational Medicine
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Sanford Health
Added 1d ago
APP - Nurse Practitioner or Physician Assistant | Occupational Medicine
Sanford Health
Rapid City, South Dakota
Caregiving & Elderly Support
Healthcare Administration
Patient Services & Wellbeing
Doctoral degree
10,000+

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Avera Health
Nurse Practitioner or Physician Assistant | Hematology & Transplant
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Avera Health
Added 1d ago
Nurse Practitioner or Physician Assistant | Hematology & Transplant
Avera Health
Sioux Falls, South Dakota
Healthcare Administration
Nursing
Patient Services & Wellbeing
10,000+

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Avera Health
Nurse Practitioner or Physician Assistant | Emergency
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Avera Health
Added 1d ago
Nurse Practitioner or Physician Assistant | Emergency
Avera Health
Aberdeen, South Dakota
Caregiving & Elderly Support
Healthcare Administration
Patient Services & Wellbeing
10,000+

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Avera Health
Nurse Practitioner or Physician Assistant | Oncology
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Avera Health
Added 1d ago
Nurse Practitioner or Physician Assistant | Oncology
Avera Health
Pierre, South Dakota
Caregiving & Elderly Support
Healthcare Administration
Patient Services & Wellbeing
10,000+

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US Department of Veterans Affairs
Advanced Practice Nurse - Primary Care
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US Department of Veterans Affairs
Added 2d ago
Advanced Practice Nurse - Primary Care
US Department of Veterans Affairs
Aberdeen, South Dakota
Account Management
Business Operations
Customer Service
$83k - $151k/yr
On-Site
Post-Master's Certificate (Nursing)
10,000+

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NP Jobs by City in South Dakota

Where South Dakota roles are concentrated, by current openings.

Sioux Falls
6 jobs
Pierre
3 jobs
Aberdeen
3 jobs
Rapid City
2 jobs
Miller
1 job
Mitchell
1 job
Watertown
1 job

NP Job Market in South Dakota

A snapshot from current South Dakota openings, updated as new roles post.

Who's Hiring

  • Avera Health
    Avera Health10
  • Sanford Health
    Sanford Health3
  • Legion Health
    Legion Health1
  • Brightside Health
    Brightside Health1
  • Great Plains Tribal Health
    Great Plains Tribal Health1

What South Dakota Employers Look For

The qualifications that appear most often in NP jobs across South Dakota.

  • Active NP license issued or recognized by the South Dakota Board of Nursing
  • Master of Science in Nursing or Doctor of Nursing Practice from an accredited program
  • National board certification from AANP or ANCC in a relevant specialty area
  • Current ANCC or AANP certification aligned with the position's patient population
  • Prescriptive authority registration with the South Dakota Board of Nursing and Pharmacy
  • Basic Life Support certification and Advanced Cardiac Life Support where clinically required

NP Jobs in South Dakota: Frequently Asked Questions

How do you become a np in South Dakota?

You become an NP in South Dakota by completing an accredited graduate nursing program, passing a national certification exam through AANP or ANCC, and applying for advanced practice registered nurse licensure through the South Dakota Board of Nursing. South Dakota grants independent practice authority to licensed NPs, meaning you can practice without a required physician collaboration agreement once licensed and credentialed.

Which companies hire nps in South Dakota?

Companies currently hiring nps in South Dakota include Avera Health, Sanford Health, and Legion Health, per current listings on Migrate Mate as of August 2026. Sanford Health and Avera Health together account for a large share of NP openings statewide, with positions distributed across clinics, hospitals, and rural access sites throughout both eastern and western South Dakota.

Which South Dakota cities have the most np jobs?

Sioux Falls, Pierre, and Aberdeen have the most NP openings in South Dakota. Sioux Falls drives the largest share as the state's biggest city and home to both Sanford Health and Avera Health headquarters, while Rapid City's volume reflects Monument Health's regional presence, and Aberdeen draws demand from Avera St. Luke's and the surrounding rural catchment area.

Are there remote np jobs in South Dakota?

Yes, but they're rare. NP work is predominantly hands-on and site-based, so most roles require in-person patient contact. About 67% of np openings tied to South Dakota are remote or hybrid as of August 2026, and those positions tend to cluster in telehealth primary care or psychiatric-mental health, where video-based care delivery is most established.

How can I get hired as a np in South Dakota with little or no experience?

The most realistic entry path is applying to new-graduate NP residency or fellowship programs, which Sanford Health and Avera Health both run for newly licensed NPs transitioning from RN roles. Candidates who have worked as registered nurses in South Dakota hospitals or rural health clinics carry a practical edge because those employers already know their clinical judgment. A completed national certification and an active South Dakota APRN license are the minimum credentials that open the door to any NP position in the state.

Where can I find and apply to np jobs in South Dakota?

You can find and apply to NP jobs in South Dakota on Migrate Mate, which lists current openings across the state. Search the roles that fit your specialty and experience level and apply directly to the ones that match.

See All 18 NP Jobs in South Dakota

Find roles in South Dakota that match your experience and apply in just a few clicks.

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