Medical Office Assistant Jobs in South Dakota

Medical Office Assistant jobs in South Dakota are open across Sioux Falls, Rapid City, and Aberdeen and other South Dakota metros, with employers like Sanford Health, Sanford Bismarck, and Sioux Center Health hiring at every experience level. Find a role that fits below and apply directly.

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Overview

Open roles184+
Top employerSanford Health
Top citySioux Falls, SD
Cities hiring18
Work type99% On-site
Top industryHealthcare

Showing 5 of 184+ Medical Office Assistant jobs

Monument Health
LPN or Medical Assistant
We won't show you this job again
Monument Health
New 1h ago
LPN or Medical Assistant
Monument Health
Rapid City, South Dakota
Nursing
Clinical Support
Healthcare Administration
Medical Assistant
Patient Services & Wellbeing
On-Site
High School

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Sanford Health
Medical Assistant
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Sanford Health
Added 2d ago
Medical Assistant
Sanford Health
Aberdeen, South Dakota
Nursing
Clinical Support
Healthcare Administration
Medical Assistant
Patient Services & Wellbeing
$19 - $25/hr
On-Site
Other
10,000+

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Monument Health
Clinical Assistant or Medical Assistant
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Monument Health
Added 5d ago
Clinical Assistant or Medical Assistant
Monument Health
Rapid City, South Dakota
Nursing
Clinical Support
Healthcare Administration
Medical Assistant
Patient Services & Wellbeing
$16 - $23/hr
On-Site
High School

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Sanford Health
Medical Assistant
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Sanford Health
Added 5d ago
Medical Assistant
Sanford Health
Rapid City, South Dakota
Nursing
Clinical Support
Healthcare Administration
Medical Assistant
Patient Services & Wellbeing
$19 - $25/hr
On-Site
None
10,000+

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Monument Health
Medical Assistant or LPN
We won't show you this job again
Monument Health
Added 1w ago
Medical Assistant or LPN
Monument Health
Rapid City, South Dakota
Nursing
Clinical Support
Healthcare Administration
Medical Assistant
Patient Services & Wellbeing
$20 - $28/hr
On-Site
High School

Have you applied for this role?

See All 184+ Medical Office Assistant Jobs in South Dakota

Find roles in South Dakota that match your experience and apply in just a few clicks.

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Medical Office Assistant Jobs by City in South Dakota

Where South Dakota roles are concentrated, by current openings.

Sioux Falls
63 jobs
Rapid City
33 jobs
Aberdeen
26 jobs
Huron
21 jobs
Sd
17 jobs
Webster
5 jobs
Canton
4 jobs
Brookings
3 jobs
Custer
2 jobs

Medical Office Assistant Job Market in South Dakota

A snapshot from current South Dakota openings, updated as new roles post.

Who's Hiring

  • Sanford Health
    Sanford Health94
  • Sanford Bismarck
    Sanford Bismarck24
  • Sioux Center Health
    Sioux Center Health22
  • Huron Regional Medical Center
    Huron Regional Medical Center20
  • Monument Health
    Monument Health18

Top Industries Hiring

  • Healthcare & Medical Services181
  • Non-Profit & Social Services31
  • Medical Devices1

What South Dakota Employers Look For

The qualifications that appear most often in medical office assistant jobs across South Dakota.

  • Experience with EHR software such as Epic, Athenahealth, or eClinicalWorks
  • High school diploma or GED, with a medical office assistant certificate preferred
  • Knowledge of medical terminology, coding basics, and insurance verification processes
  • Strong patient communication skills and front-desk or reception experience
  • Certified Medical Administrative Assistant (CMAA) or equivalent credential often preferred
  • Proficiency in scheduling software, multi-line phone systems, and basic billing workflows

Medical Office Assistant Jobs in South Dakota: Frequently Asked Questions

How many medical office assistant jobs are there in South Dakota?

There are 184+ medical office assistant openings in South Dakota on Migrate Mate as of June 2026, with the most roles in Sioux Falls, Rapid City, and Aberdeen. New positions post regularly as employers across South Dakota hire.

How much do medical office assistants make in South Dakota?

Medical office assistants in South Dakota earn a median of about $41,870 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $35,980 for the lowest 10% to over $48,960 for the top 10%. Pay rises with experience, specialty, and employer.

Which South Dakota cities have the most medical office assistant jobs?

Sioux Falls, Rapid City, and Aberdeen have the most medical office assistant openings in South Dakota right now, with additional roles spread across smaller metros statewide.

Which companies hire medical office assistants in South Dakota?

Employers hiring medical office assistants in South Dakota include Sanford Health, Sanford Bismarck, and Sioux Center Health, based on current listings on Migrate Mate as of June 2026.

Are there remote medical office assistant jobs in South Dakota?

Yes. About 1% of medical office assistant openings tied to South Dakota are remote or hybrid as of June 2026. The rest are on-site roles based in South Dakota metros.

How do I apply for medical office assistant jobs in South Dakota?

You can apply to medical office assistant jobs in South Dakota directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred South Dakota location, then apply to each one that fits.

See All 184+ Medical Office Assistant Jobs in South Dakota

Find roles in South Dakota that match your experience and apply in just a few clicks.

Find Medical Office Assistant Jobs