Clinical Registered Nurse Jobs in South Dakota

Clinical Registered Nurse jobs in South Dakota are open across Sioux Falls, Rapid City, and Sd and other South Dakota metros, with employers like Monument Health, Sanford Bismarck, and Sanford Health hiring at every experience level. Find a role that fits below and apply directly.

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Overview

Open roles8+
Top employerMonument Health
Top citySioux Falls, SD
Cities hiring4
Work type100% On-site
Top industryHealthcare

Showing 5 of 8+ Clinical Registered Nurse jobs

Monument Health
Clinical Research Registered Nurse
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Monument Health
Added 3d ago
Clinical Research Registered Nurse
Monument Health
Rapid City, South Dakota
Nursing
Clinical Support
Healthcare Administration
$32 - $40/hr
On-Site
Bachelor's

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Monument Health
Clinical Research Registered Nurse
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Monument Health
Added 1mo ago
Clinical Research Registered Nurse
Monument Health
Rapid City, South Dakota
Nursing
Clinical Support
Healthcare Administration
$67k - $83k/yr
On-Site
Associate's

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Sanford Health
Registered Nurse - Clinical Research Coordinator
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Sanford Health
Added 1mo ago
Registered Nurse - Clinical Research Coordinator
Sanford Health
Sioux Falls, South Dakota
Nursing
Clinical Support
Healthcare Administration
$27 - $44/hr
On-Site
Bachelor's
10,000+

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Sanford Bismarck
RN Clinical Care Leader - FT - LTC - SF Village
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Sanford Bismarck
Added 1mo ago
RN Clinical Care Leader - FT - LTC - SF Village
Sanford Bismarck
Sd, South Dakota
On-Site
Associate's

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Sanford Bismarck
RN Clinical Research Coordinator - Imagenetics Research
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Sanford Bismarck
Added 2mo ago
RN Clinical Research Coordinator - Imagenetics Research
Sanford Bismarck
Sd, South Dakota
On-Site
Associate's

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See All 8 Clinical Registered Nurse Jobs in South Dakota

Find roles in South Dakota that match your experience and apply in just a few clicks.

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Clinical Registered Nurse Jobs by City in South Dakota

Where South Dakota roles are concentrated, by current openings.

Sioux Falls
3 jobs
Rapid City
2 jobs
Sd
2 jobs
Aberdeen
1 jobs

Clinical Registered Nurse Job Market in South Dakota

A snapshot from current South Dakota openings, updated as new roles post.

Who's Hiring

  • Monument Health
    Monument Health2
  • Sanford Bismarck
    Sanford Bismarck2
  • Sanford Health
    Sanford Health2
  • Sioux Center Health
    Sioux Center Health2

Top Industries Hiring

  • Healthcare & Medical Services8

What South Dakota Employers Look For

The qualifications that appear most often in clinical registered nurse jobs across South Dakota.

  • Active RN licensure in the state of employment or compact license eligibility
  • Current BLS and ACLS certification from an approved provider
  • Associate or bachelor's degree in nursing from an accredited program
  • Minimum one to two years of clinical nursing experience in an acute care setting
  • Proficiency with electronic health record systems such as Epic or Cerner
  • Strong clinical assessment skills and experience with patient care documentation

Clinical Registered Nurse Jobs in South Dakota: Frequently Asked Questions

How many clinical registered nurse jobs are there in South Dakota?

There are 8+ clinical registered nurse openings in South Dakota on Migrate Mate as of June 2026, with the most roles in Sioux Falls, Rapid City, and Sd. New positions post regularly as employers across South Dakota hire.

How much do clinical registered nurses make in South Dakota?

Clinical registered nurses in South Dakota earn a median of about $78,060 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $54,040 for the lowest 10% to over $98,220 for the top 10%. Pay rises with experience, specialty, and employer.

Which South Dakota cities have the most clinical registered nurse jobs?

Sioux Falls, Rapid City, and Sd have the most clinical registered nurse openings in South Dakota right now, with additional roles spread across smaller metros statewide.

Which companies hire clinical registered nurses in South Dakota?

Employers hiring clinical registered nurses in South Dakota include Monument Health, Sanford Bismarck, and Sanford Health, based on current listings on Migrate Mate as of June 2026.

Are there remote clinical registered nurse jobs in South Dakota?

Yes. About 0% of clinical registered nurse openings tied to South Dakota are remote or hybrid as of June 2026. The rest are on-site roles based in South Dakota metros.

How do I apply for clinical registered nurse jobs in South Dakota?

You can apply to clinical registered nurse jobs in South Dakota directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred South Dakota location, then apply to each one that fits.

See All 8 Clinical Registered Nurse Jobs in South Dakota

Find roles in South Dakota that match your experience and apply in just a few clicks.

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