Nurse Practitioner Jobs in South Dakota
Nurse Practitioner jobs in South Dakota are concentrated in primary care, rural health, and behavioral health, with demand running from new graduates through experienced autonomous practitioners across a state where NPs often serve as the primary provider for entire communities. The busiest hiring markets are Sioux Falls, Rapid City, and Aberdeen, anchored by large systems such as Sanford Health, Monument Health, and Avera Health. The most active openings are in family practice, psychiatric-mental health, and urgent care. Scan the live roles below and apply to whichever ones fit.
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Careers With Purpose
Sanford Health, the largest rural health system in the United States, is dedicated to transforming the health care experience and providing access to world-class health care in America’s heartland.
Facility: Black Hills Plastic Surg
Location: Rapid City, SD
Address: 3615 5th St, Rapid City, SD 57701, USA
Shift: 8 Hours - Day Shifts
Job Schedule: Full time
Weekly Hours: 36.00
Department Details
Monday through Friday Daytime Hours
Light Call
Mainly Work in the Clinic with Limited OR Assist
Dynamic office
Strong emphasis on patient safety and education
Job Summary
The Physician Assistant (PA) is a licensed medical professional who practices medicine in collaboration with physicians and other care team members. The PA evaluates, diagnoses, and manages patient health concerns across the lifespan, provides preventive services, and coordinates care to promote optimal health outcomes. Perform patient assessments, including medical histories and physical examinations. Diagnose and manage acute and chronic conditions within scope of practice. Order, review, and interpret diagnostic tests and imaging studies. Prescribe medications, therapies, and other treatments in compliance with regulations. Educate and counsel patients and families on health maintenance, disease prevention, and treatment plans. May perform procedures & treatments within scope of practice & assist with procedures & treatments when indicated.
Collaborate with interdisciplinary team members to ensure continuity of care. Maintain accurate, timely, and thorough documentation in the electronic medical record (EMR). Participate in quality, safety, and performance improvement activities.
Qualifications
Completion of a Physician Assistant program accredited by the ARC-PA or equivalent accrediting program accepted by the state licensing board.
Clinical experience in specialty area is preferred but not required.
Current licensure as a Physician Assistant in each state of practice.
Current Drug Enforcement Administration (DEA) permit to prescribe controlled substances in each state of practice.
State Controlled Substance License (if required by State)
Current certification by the National Commission on Certification of Physician Assistants (NCCPA).
Privileging documents and related credentialing requirements will supersede this job description in defining minimum qualifications, criteria, and scope of practice, if variation between documents exists
Benefits
Sanford offers an attractive benefits package for qualifying full-time and part-time employees. Depending on eligibility, a variety of benefits include health insurance, dental insurance, vision insurance, life insurance, a 401(k) retirement plan, work/life balance benefits, and a generous time off package to maintain a healthy home-work balance. For more information about Total Rewards, visit https://sanfordcareers.com/benefits .
Sanford is an EEO/AA Employer M/F/Disability/Vet. If you are an individual with a disability and would like to request an accommodation for help with your online application, please call 1-877-673-0854 or send an email to talent@sanfordhealth.org .
Practice Details: Come work in the Sanford Black Hills Plastic Surgery Clinic with two experienced plastic surgeons. The role includes working in the office as well as assisting in surgery. There is an opportunity to build an aesthetic practice with injectables, skin care and laser treatments.
Job Summary
The Plastic Surgery Advanced Practice Provider provides care to patients undergoing cosmetic and reconstructive surgical procedures and works in collaboration with plastic surgeons to manage preoperative assessments, assist in surgery, and provide postoperative care. Additionally, the APP provides patient education, ensuring optimal outcomes and patient satisfaction. The motivated APP has the opportunity to perform aesthetic procedures such as neurotoxin and filler injections, chemical peels, microneedling and laser treatments, and may build their own practice in the clinic.
Specific duties include:
Participate in outpatient clinics, surgical procedures, and follow-up visits.
Assist in surgical planning and provide preoperative counseling and education on procedures, risks, and recovery.
Order and interpret diagnostic tests such as imaging and lab work relevant to plastic surgery.
Hospital responsibilities of first assisting in surgery and conducting post-op /inpatient rounds.
Manage postoperative care including wound care, pain management, monitoring complications, and scar treatment.
Document patient care accurately and timely in electronic health records.
Qualifications
Successful completion of a physician assistant program accredited by the Accreditation Review Commission on Education for the Physician Assistant (ARC-PA) or its predecessors, alternatively successful completion of a Master’s or Doctorate degree from an accredited Nurse Practitioner program.
Licensed or eligible for licensure as a Physician Assistant or Nurse Practitioner in the State of South Dakota and possess NCCPA or AANP/ANCC certification.
Possession of or eligible for Federal Drug Enforcement Administration (DEA) and South Dakota State Controlled Substance License to prescribe controlled substances.
Privileging documents and related credentialing requirements will supersede this job description in defining minimum qualifications, criteria, and scope of practice, if variation between documents exists
Compensation Package: Benefits
Sanford offers an attractive benefits package for qualifying full-time and part-time employees. Depending on eligibility, a variety of benefits include health insurance, dental insurance, vision insurance, life insurance, a 401(k)-retirement plan, work/life balance benefits, and a generous time off package to maintain a healthy home-work balance. For more information about Total Rewards, visit https://sanfordcareers.com/benefits .
Sanford is an EEO/AA Employer M/F/Disability/Vet. If you are an individual with a disability and would like to request an accommodation for help with your online application, please call 1-877-673-0854 or send an email to talent@sanfordhealth.org
About this Community: Rapid City’s vibrant downtown, healthy business community and wealth of cultural offerings make Rapid City the perfect place to raise a family. There are endless opportunities to explore a rich history and culture or take in recreational adventures and scenic wonders. From awe-inspiring natural wonders to captivating local experiences, Rapid City embodies all the characteristics of an ideal community.
Sanford has a Drug Free Workplace Policy. An accepted offer will require a drug screen and pre-employment background screening as a condition of employment.
Req Number: R-0278938
Job Function: Advanced Practice Provider
Featured: No
Specialty: Plastic & Reconstruction
Visas Accepted: N/A
See All 19 Nurse Practitioner Jobs in South Dakota
Find roles in South Dakota that match your experience and apply in just a few clicks.
Find Nurse Practitioner JobsNurse Practitioner Jobs by City in South Dakota
Where South Dakota roles are concentrated, by current openings.
Nurse Practitioner Job Market in South Dakota
A snapshot from current South Dakota openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Healthcare & Medical Services
What South Dakota Employers Look For
The qualifications that appear most often in nurse practitioner jobs across South Dakota.
- Active South Dakota nurse practitioner license issued by the South Dakota Board of Nursing
- Master of Science in Nursing or Doctor of Nursing Practice from an accredited program
- Current national certification from AANP or ANCC in a relevant NP specialty
- Active, unrestricted registered nurse license in South Dakota or a compact state
- Current BLS and ACLS certification required for most clinical settings
- Experience with electronic health records platforms such as Epic or Cerner
Nurse Practitioner Jobs in South Dakota: Frequently Asked Questions
How do you become a nurse practitioner in South Dakota?
You must hold a current registered nurse license and complete a graduate-level NP program, then obtain national certification through AANP or ANCC in your chosen specialty. The South Dakota Board of Nursing issues the advanced practice registered nurse license required to practice in the state. South Dakota participates in the Nurse Licensure Compact, so compact RN license holders may practice without an additional state RN license, though a separate South Dakota APRN authorization is still required.
How much do nurse practitioners make in South Dakota?
Nurse practitioners in South Dakota earn a median of about $128,840 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $103,080 for the lowest 10% to over $156,000 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire nurse practitioners in South Dakota?
South Dakota nurse practitioner roles are posted by Avera Health, Sanford Health, and Monument Health and others right now, based on current listings on Migrate Mate as of October 2026. Sanford Health, Avera Health, and Monument Health are long-standing anchor employers across the state, with openings distributed among hospital campuses, rural clinic networks, and specialty outpatient settings.
Which South Dakota cities have the most nurse practitioner jobs?
Rapid City, Sioux Falls, and Aberdeen have the most nurse practitioner openings in South Dakota. Sioux Falls drives the largest share as the home base of Sanford Health and Avera Health headquarters, while Rapid City is anchored by Monument Health and a growing specialty care market, and Aberdeen reflects strong regional demand from Avera and rural critical-access facilities serving the northern part of the state.
Are there remote nurse practitioner jobs in South Dakota?
Yes, but they are rare. About 0% of nurse practitioner openings tied to South Dakota are remote or hybrid as of October 2026, reflecting how hands-on the role is in most clinical settings. The portion of the role most likely to be performed remotely is telehealth primary care or psychiatric evaluation, where a small but growing number of South Dakota employers have established virtual care programs.
How can I get hired as a nurse practitioner in South Dakota with little or no experience?
The most realistic entry path is applying for new-graduate NP positions within the large integrated health systems, where structured support is built in. Sanford Health and Avera Health both offer transition-to-practice programs designed for newly certified NPs, pairing them with supervising physicians or experienced practitioners during the first year. Candidates coming from roles such as RN charge nurse, ICU nurse, or clinic nurse coordinator carry the most transferable credibility, and holding a completed South Dakota APRN license before applying puts you ahead of candidates still awaiting authorization.
Where can I find and apply to nurse practitioner jobs in South Dakota?
You can find and apply to nurse practitioner jobs in South Dakota on Migrate Mate, which lists current openings across the state. Search the available roles, find the ones that match your specialty and preferred setting, and apply directly to the ones that fit.
See All 19 Nurse Practitioner Jobs in South Dakota
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