Nurse Practitioner Jobs in South Dakota

Nurse Practitioner jobs in South Dakota are concentrated in primary care, rural health, and behavioral health, with demand running from new graduates through experienced autonomous practitioners across a state where NPs often serve as the primary provider for entire communities. The busiest hiring markets are Sioux Falls, Rapid City, and Aberdeen, anchored by large systems such as Sanford Health, Monument Health, and Avera Health. The most active openings are in family practice, psychiatric-mental health, and urgent care. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles19
Top employerAvera Health
Top cityRapid City, SD
Cities hiring11
Work type100% On-site
Top industryHealthcare

Showing 5 of 19+ Nurse Practitioner jobs

APP - Nurse Practitioner or Physician Assistant | Plastic Surgery
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New 15h ago
APP - Nurse Practitioner or Physician Assistant | Plastic Surgery
Sanford Health
Rapid City, South Dakota
Caregiving & Elderly Support
Healthcare Administration
Patient Services & Wellbeing
Doctoral degree
10,000+

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Wound Care Physician- MD, NP, PA
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Added 4d ago
Wound Care Physician- MD, NP, PA
Wound Healing Care Specialists Inc.
South Dakota
Caregiving & Elderly Support
Healthcare Administration
Patient Services & Wellbeing
On-Site
11-50

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Advanced Practice Provider - General & Bariatric Surgery
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Advanced Practice Provider - General & Bariatric Surgery
Monument Health
Rapid City, South Dakota
Caregiving & Elderly Support
Healthcare Administration
Patient Services & Wellbeing

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Part-Time Family Nurse Practitioner (FNP)
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Part-Time Family Nurse Practitioner (FNP)
Melmedic LLC
Sturgis, South Dakota
Healthcare Administration
Nursing
Patient Services & Wellbeing
On-Site

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APP - Nurse Practitioner or Physician Assistant | Interventional Radiology
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APP - Nurse Practitioner or Physician Assistant | Interventional Radiology
Sanford Health
Sioux Falls, South Dakota
Allied Health
Healthcare Administration
Nursing
10,000+

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Nurse Practitioner Jobs by City in South Dakota

Where South Dakota roles are concentrated, by current openings.

Rapid City
4 jobs
Sioux Falls
4 jobs
Aberdeen
2 jobs
Nemo
1 job
Pierre
1 job
Gregory
1 job
Sturgis
1 job
Sisseton
1 job
Brookings
1 job

Nurse Practitioner Job Market in South Dakota

A snapshot from current South Dakota openings, updated as new roles post.

Who's Hiring

Avera Health6 open roles
Sanford Health3 open roles
Monument Health2 open roles

Top Industries Hiring

  • Healthcare & Medical Services

What South Dakota Employers Look For

The qualifications that appear most often in nurse practitioner jobs across South Dakota.

  • Active South Dakota nurse practitioner license issued by the South Dakota Board of Nursing
  • Master of Science in Nursing or Doctor of Nursing Practice from an accredited program
  • Current national certification from AANP or ANCC in a relevant NP specialty
  • Active, unrestricted registered nurse license in South Dakota or a compact state
  • Current BLS and ACLS certification required for most clinical settings
  • Experience with electronic health records platforms such as Epic or Cerner

Nurse Practitioner Jobs in South Dakota: Frequently Asked Questions

How do you become a nurse practitioner in South Dakota?

You must hold a current registered nurse license and complete a graduate-level NP program, then obtain national certification through AANP or ANCC in your chosen specialty. The South Dakota Board of Nursing issues the advanced practice registered nurse license required to practice in the state. South Dakota participates in the Nurse Licensure Compact, so compact RN license holders may practice without an additional state RN license, though a separate South Dakota APRN authorization is still required.

How much do nurse practitioners make in South Dakota?

Nurse practitioners in South Dakota earn a median of about $128,840 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $103,080 for the lowest 10% to over $156,000 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire nurse practitioners in South Dakota?

South Dakota nurse practitioner roles are posted by Avera Health, Sanford Health, and Monument Health and others right now, based on current listings on Migrate Mate as of October 2026. Sanford Health, Avera Health, and Monument Health are long-standing anchor employers across the state, with openings distributed among hospital campuses, rural clinic networks, and specialty outpatient settings.

Which South Dakota cities have the most nurse practitioner jobs?

Rapid City, Sioux Falls, and Aberdeen have the most nurse practitioner openings in South Dakota. Sioux Falls drives the largest share as the home base of Sanford Health and Avera Health headquarters, while Rapid City is anchored by Monument Health and a growing specialty care market, and Aberdeen reflects strong regional demand from Avera and rural critical-access facilities serving the northern part of the state.

Are there remote nurse practitioner jobs in South Dakota?

Yes, but they are rare. About 0% of nurse practitioner openings tied to South Dakota are remote or hybrid as of October 2026, reflecting how hands-on the role is in most clinical settings. The portion of the role most likely to be performed remotely is telehealth primary care or psychiatric evaluation, where a small but growing number of South Dakota employers have established virtual care programs.

How can I get hired as a nurse practitioner in South Dakota with little or no experience?

The most realistic entry path is applying for new-graduate NP positions within the large integrated health systems, where structured support is built in. Sanford Health and Avera Health both offer transition-to-practice programs designed for newly certified NPs, pairing them with supervising physicians or experienced practitioners during the first year. Candidates coming from roles such as RN charge nurse, ICU nurse, or clinic nurse coordinator carry the most transferable credibility, and holding a completed South Dakota APRN license before applying puts you ahead of candidates still awaiting authorization.

Where can I find and apply to nurse practitioner jobs in South Dakota?

You can find and apply to nurse practitioner jobs in South Dakota on Migrate Mate, which lists current openings across the state. Search the available roles, find the ones that match your specialty and preferred setting, and apply directly to the ones that fit.

See All 19 Nurse Practitioner Jobs in South Dakota

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