Nurse Practitioner Jobs in South Dakota
Nurse Practitioner jobs in South Dakota are concentrated in primary care, rural health, and behavioral health, with demand running from new graduates through experienced autonomous practitioners across a state where NPs often serve as the primary provider for entire communities. The busiest hiring markets are Sioux Falls, Rapid City, and Aberdeen, anchored by large systems such as Sanford Health, Monument Health, and Avera Health. The most active openings are in family practice, psychiatric-mental health, and urgent care. Scan the live roles below and apply to whichever ones fit.
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Showing 5 of 18+ Nurse Practitioner jobs
Careers With Purpose
Sanford Health, the largest rural health system in the United States, is dedicated to transforming the health care experience and providing access to world-class health care in America’s heartland.
Facility: Black Hills Haines Urg Care
Location: Rapid City, SD
Address: 1730 Haines Ave, Rapid City, SD 57701, USA
Shift: 8 Hours - Day Shifts
Job Schedule: Full time
Weekly Hours: 40.00
Job Summary
The Occupational Medicine Nurse Practitioner provides advanced nursing care focused on the prevention, evaluation, treatment, and management of work-related injuries and illnesses. The NP works in collaboration with physicians, employers, safety personnel, and healthcare providers to promote employee health, ensure regulatory compliance, and support safe return-to-work strategies. Evaluate, diagnose, and treat work-related injuries and illnesses in accordance with occupational health standards and regulatory guidelines.
Conduct pre-employment, periodic, and return-to-work physical examinations.
Perform functional capacity evaluations (FCEs), drug and alcohol testing, TB screenings, immunizations, and other health surveillance exams.
Collaborate with employers to support workers' compensation claims and return-to-work planning.
Educate patients on injury prevention, ergonomics, safe work practices, and chronic disease management.
Maintain detailed documentation in compliance with OSHA, DOT, and state/federal guidelines.
Communicate with case managers, safety officers, and HR departments to coordinate employee care.
Participate in wellness and health promotion programs tailored to the workplace.
Assist in the development of occupational health protocols and policies.
Ensure timely and appropriate referral to specialty care as needed.
Qualifications
Master’s or Doctorate degree from an accredited Nurse Practitioner program.
If APRN was licensed prior to August 1, 1995, master's degree in nursing is preferred.
Experience in occupational medicine, urgent care, emergency medicine, or internal medicine preferred.
Current licensure as a Registered Nurse and Nurse Practitioner in each state of practice.
Current Drug Enforcement Administration (DEA) permit to prescribe controlled substances in each state of practice.
State Controlled Substance License (if required by State)
National board certification as a Family (FNP-BC) or (FNP–C), Adult-Gerontology Primary Care (AGPCNP-BC) or (A-GNP), Adult (ANP-C).
Obtains and subsequently maintains required specific competencies and certifications as outlined on privilege form.
Privileging documents and related credentialing requirements will supersede this job description in defining minimum qualifications, criteria, and scope of practice, if variation between documents exists.
Benefits
Sanford offers an attractive benefits package for qualifying full-time and part-time employees. Depending on eligibility, a variety of benefits include health insurance, dental insurance, vision insurance, life insurance, a 401(k) retirement plan, work/life balance benefits, and a generous time off package to maintain a healthy home-work balance. For more information about Total Rewards, visit https://sanfordcareers.com/benefits .
Sanford is an EEO/AA Employer M/F/Disability/Vet. If you are an individual with a disability and would like to request an accommodation for help with your online application, please call 1-877-673-0854 or send an email to talent@sanfordhealth.org .
Sanford has a Drug Free Workplace Policy. An accepted offer will require a drug screen and pre-employment background screening as a condition of employment.
Req Number: R-0272511
Job Function: Advanced Practice Provider
Featured: No
Visas Accepted: N/A
Careers With Purpose
Sanford Health, the largest rural health system in the United States, is dedicated to transforming the health care experience and providing access to world-class health care in America’s heartland.
Facility: Black Hills Haines Urg Care
Location: Rapid City, SD
Address: 1730 Haines Ave, Rapid City, SD 57701, USA
Shift: 8 Hours - Day Shifts
Job Schedule: Full time
Weekly Hours: 40.00
Job Summary
The Occupational Medicine Nurse Practitioner provides advanced nursing care focused on the prevention, evaluation, treatment, and management of work-related injuries and illnesses. The NP works in collaboration with physicians, employers, safety personnel, and healthcare providers to promote employee health, ensure regulatory compliance, and support safe return-to-work strategies. Evaluate, diagnose, and treat work-related injuries and illnesses in accordance with occupational health standards and regulatory guidelines.
Conduct pre-employment, periodic, and return-to-work physical examinations.
Perform functional capacity evaluations (FCEs), drug and alcohol testing, TB screenings, immunizations, and other health surveillance exams.
Collaborate with employers to support workers' compensation claims and return-to-work planning.
Educate patients on injury prevention, ergonomics, safe work practices, and chronic disease management.
Maintain detailed documentation in compliance with OSHA, DOT, and state/federal guidelines.
Communicate with case managers, safety officers, and HR departments to coordinate employee care.
Participate in wellness and health promotion programs tailored to the workplace.
Assist in the development of occupational health protocols and policies.
Ensure timely and appropriate referral to specialty care as needed.
Qualifications
Master’s or Doctorate degree from an accredited Nurse Practitioner program.
If APRN was licensed prior to August 1, 1995, master's degree in nursing is preferred.
Experience in occupational medicine, urgent care, emergency medicine, or internal medicine preferred.
Current licensure as a Registered Nurse and Nurse Practitioner in each state of practice.
Current Drug Enforcement Administration (DEA) permit to prescribe controlled substances in each state of practice.
State Controlled Substance License (if required by State)
National board certification as a Family (FNP-BC) or (FNP–C), Adult-Gerontology Primary Care (AGPCNP-BC) or (A-GNP), Adult (ANP-C).
Obtains and subsequently maintains required specific competencies and certifications as outlined on privilege form.
Privileging documents and related credentialing requirements will supersede this job description in defining minimum qualifications, criteria, and scope of practice, if variation between documents exists.
Benefits
Sanford offers an attractive benefits package for qualifying full-time and part-time employees. Depending on eligibility, a variety of benefits include health insurance, dental insurance, vision insurance, life insurance, a 401(k) retirement plan, work/life balance benefits, and a generous time off package to maintain a healthy home-work balance. For more information about Total Rewards, visit https://sanfordcareers.com/benefits .
Sanford is an EEO/AA Employer M/F/Disability/Vet. If you are an individual with a disability and would like to request an accommodation for help with your online application, please call 1-877-673-0854 or send an email to talent@sanfordhealth.org .
Sanford has a Drug Free Workplace Policy. An accepted offer will require a drug screen and pre-employment background screening as a condition of employment.
Req Number: R-0272511
Job Function: Advanced Practice Provider
Featured: No
Visas Accepted: N/A
See All 18 Nurse Practitioner Jobs in South Dakota
Find roles in South Dakota that match your experience and apply in just a few clicks.
Find Nurse Practitioner JobsNurse Practitioner Jobs by City in South Dakota
Where South Dakota roles are concentrated, by current openings.
Nurse Practitioner Job Market in South Dakota
A snapshot from current South Dakota openings, updated as new roles post.
Who's Hiring
- Avera Health10
- Sanford Health3
- Legion Health1
- Brightside Health1
- Great Plains Tribal Health1
What South Dakota Employers Look For
The qualifications that appear most often in nurse practitioner jobs across South Dakota.
- Active South Dakota nurse practitioner license issued by the South Dakota Board of Nursing
- Master of Science in Nursing or Doctor of Nursing Practice from an accredited program
- Current national certification from AANP or ANCC in a relevant NP specialty
- Active, unrestricted registered nurse license in South Dakota or a compact state
- Current BLS and ACLS certification required for most clinical settings
- Experience with electronic health records platforms such as Epic or Cerner
Nurse Practitioner Jobs in South Dakota: Frequently Asked Questions
How do you become a nurse practitioner in South Dakota?
You must hold a current registered nurse license and complete a graduate-level NP program, then obtain national certification through AANP or ANCC in your chosen specialty. The South Dakota Board of Nursing issues the advanced practice registered nurse license required to practice in the state. South Dakota participates in the Nurse Licensure Compact, so compact RN license holders may practice without an additional state RN license, though a separate South Dakota APRN authorization is still required.
How much do nurse practitioners make in South Dakota?
Nurse practitioners in South Dakota earn a median of about $128,840 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $103,080 for the lowest 10% to over $156,000 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire nurse practitioners in South Dakota?
South Dakota nurse practitioner roles are posted by Avera Health, Sanford Health, and Legion Health and others right now, based on current listings on Migrate Mate as of August 2026. Sanford Health, Avera Health, and Monument Health are long-standing anchor employers across the state, with openings distributed among hospital campuses, rural clinic networks, and specialty outpatient settings.
Which South Dakota cities have the most nurse practitioner jobs?
Sioux Falls, Pierre, and Aberdeen have the most nurse practitioner openings in South Dakota. Sioux Falls drives the largest share as the home base of Sanford Health and Avera Health headquarters, while Rapid City is anchored by Monument Health and a growing specialty care market, and Aberdeen reflects strong regional demand from Avera and rural critical-access facilities serving the northern part of the state.
Are there remote nurse practitioner jobs in South Dakota?
Yes, but they are rare. About 67% of nurse practitioner openings tied to South Dakota are remote or hybrid as of August 2026, reflecting how hands-on the role is in most clinical settings. The portion of the role most likely to be performed remotely is telehealth primary care or psychiatric evaluation, where a small but growing number of South Dakota employers have established virtual care programs.
How can I get hired as a nurse practitioner in South Dakota with little or no experience?
The most realistic entry path is applying for new-graduate NP positions within the large integrated health systems, where structured support is built in. Sanford Health and Avera Health both offer transition-to-practice programs designed for newly certified NPs, pairing them with supervising physicians or experienced practitioners during the first year. Candidates coming from roles such as RN charge nurse, ICU nurse, or clinic nurse coordinator carry the most transferable credibility, and holding a completed South Dakota APRN license before applying puts you ahead of candidates still awaiting authorization.
Where can I find and apply to nurse practitioner jobs in South Dakota?
You can find and apply to nurse practitioner jobs in South Dakota on Migrate Mate, which lists current openings across the state. Search the available roles, find the ones that match your specialty and preferred setting, and apply directly to the ones that fit.
See All 18 Nurse Practitioner Jobs in South Dakota
Find roles in South Dakota that match your experience and apply in just a few clicks.
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