Physician Assistant Jobs in South Dakota

Physician assistant jobs in South Dakota concentrate in primary care, family medicine, and hospital-based specialties, with strong demand across rural health clinics and tribal health systems that serve the state's dispersed population. Most hiring is in Sioux Falls, Rapid City, and Aberdeen, where established systems like Sanford Health, Monument Health, and Avera Health anchor the market at every level from new graduate to senior clinician. Orthopedics, urgent care, and surgical assistance are among the most consistently in-demand specialties statewide. Find a role that fits below and apply directly.

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Overview

Open roles14
Top employerAvera Health
Top cityYankton, SD
Cities hiring9
Work type100% On-site
Top credentialATLS Certification

Showing 5 of 14+ Physician Assistant jobs

Wound Care Physician- MD, NP, PA
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Wound Care Physician- MD, NP, PA
Wound Healing Care Specialists Inc.
South Dakota
Caregiving & Elderly Support
Healthcare Administration
Patient Services & Wellbeing
On-Site
11-50

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APP - Nurse Practitioner or Physician Assistant | Interventional Radiology
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APP - Nurse Practitioner or Physician Assistant | Interventional Radiology
Sanford Health
Sioux Falls, South Dakota
Allied Health
Healthcare Administration
Nursing
10,000+

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Nurse Practitioner or Physician Assistant
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Nurse Practitioner or Physician Assistant
Horizon Health
Wessington Springs, South Dakota
Caregiving & Elderly Support
Healthcare Administration
Patient Services & Wellbeing
ATLS Certification
1,001-5,000

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Physician Assistant or Nurse Practition | Family Medicine
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Added 6d ago
Physician Assistant or Nurse Practition | Family Medicine
Avera Health
Yankton, South Dakota
Allied Health
Healthcare Administration
Nursing
10,000+

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Nurse Practitioner or Physician Assistant | Acute Care
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Added 1w ago
Nurse Practitioner or Physician Assistant | Acute Care
Avera Health
Brookings, South Dakota
Allied Health
Clinical Support
Healthcare Administration
10,000+

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See All 14 Physician Assistant Jobs in South Dakota

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Physician Assistant Jobs by City in South Dakota

Where South Dakota roles are concentrated, by current openings.

Yankton
2 jobs
Aberdeen
2 jobs
Rapid City
2 jobs
Sioux Falls
2 jobs
Wagner
1 job
Gregory
1 job
Sisseton
1 job
Brookings
1 job
Wessington Springs
1 job

Physician Assistant Job Market in South Dakota

A snapshot from current South Dakota openings, updated as new roles post.

Who's Hiring

Avera Health7 open roles
Sanford Health2 open roles
10XG1 open role

What South Dakota Employers Look For

The qualifications that appear most often in physician assistant jobs across South Dakota.

  • Active South Dakota physician assistant license issued by the South Dakota Board of Medical Examiners
  • National Commission on Certification of Physician Assistants certification, including passing PANCE
  • Master's degree or higher from an ARC-PA accredited physician assistant program
  • Current DEA registration and state-level prescribing authority where required by employer
  • Basic Life Support and Advanced Cardiovascular Life Support certification from an accredited provider
  • Experience with electronic health records such as Epic, Cerner, or comparable clinical platforms

Physician Assistant Jobs in South Dakota: Frequently Asked Questions

How do you become a physician assistant in South Dakota?

To become a physician assistant in South Dakota, you must earn a master's degree from an ARC-PA accredited program, pass the PANCE, and apply for licensure through the South Dakota Board of Medical Examiners. The board requires proof of certification, a completed application, and background check. South Dakota also requires a written collaborative agreement with a supervising physician before you can begin practicing, which most employers arrange as part of the hiring process.

How much do physician assistants make in South Dakota?

Physician assistants in South Dakota earn a median of about $133,200 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $104,660 for the lowest 10% to over $158,020 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire physician assistants in South Dakota?

Employers hiring physician assistants in South Dakota right now include Avera Health, Sanford Health, and 10XG, based on current listings on Migrate Mate as of October 2026. South Dakota's market is anchored by large integrated health systems that operate both urban clinics and rural outreach sites, giving physician assistants exposure to a wide range of care settings across the state.

Which South Dakota cities have the most physician assistant jobs?

The cities with the most physician assistant openings in South Dakota are Yankton, Aberdeen, and Rapid City. Sioux Falls drives the largest share of listings as home to Sanford Health and Avera Health's flagship campuses, while Rapid City reflects Monument Health's regional footprint in western South Dakota, and smaller markets like Aberdeen see steady demand from rural health systems serving surrounding agricultural communities.

Are there remote physician assistant jobs in South Dakota?

Yes, but they're rare. Physician assistant work is fundamentally hands-on and patient-facing, which limits remote arrangements to a small share of roles. About 0% of physician assistant openings tied to South Dakota are remote or hybrid as of October 2026, and those positions are most commonly in telehealth urgent care, behavioral health consultation, or care management review rather than primary clinical practice.

How can I get hired as a physician assistant in South Dakota with little or no experience?

The most realistic entry path is applying to new-graduate or early-career postings at Sanford Health and Avera Health, both of which recruit directly from ARC-PA accredited programs and offer structured onboarding for new clinicians. Candidates coming from adjacent roles such as medical assistant, EMT, or RN also transition into PA positions after completing their degree. Having your South Dakota Board of Medical Examiners application started and a collaborative agreement ready before you interview signals readiness that most new-grad candidates lack.

Where can I find and apply to physician assistant jobs in South Dakota?

You can find and apply to physician assistant jobs in South Dakota on Migrate Mate, which lists current openings across the state. Search the listings for roles that match your specialty, experience level, and preferred location, then apply directly to the positions that fit.

See All 14 Physician Assistant Jobs in South Dakota

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