NP Jobs in Indianapolis, IN
NP jobs in Indianapolis are in strong demand, concentrated in the Meridian-Kessler medical corridor, downtown, and the North Meridian Street healthcare district across primary care, acute care, and behavioral health settings. Employers actively hiring include Indiana University Health, Ascension, and HarmonyCares. See the openings below and apply to the ones that match your experience.
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IU Health Medical Group is hiring! We are seeking a Nurse Practitioner or Physician Assistant to join our Orthopedic Trauma team at Methodist Hospital in Indianapolis, IN!
Position Details:
- PRN
- Day Shift
- Shifts available based coverage needs.
- Minimum of 8 hours every 6 weeks
- No call
- 80% Inpatient and 20% Outpatient
- Team includes 8 physicians and 16 advanced practice providers
Key Responsibilities:
- Orthopedic Trauma consults
- Inpatient Rounding
Procedures:
- Fracture/dislocation reductions
- Application of splints
- First Assist in the OR
- Joint Injections
- Joint Aspirations
- Wound Vac application and changes
- Traction Application
Qualifications:
- ACNP, AGNP, FNP or PA certification required
- At least 1 year of APP experience required
- APP experience in orthopedics preferred
Compensation Details:
- We offer a strong compensation model
- Comprehensive benefits package includes group insurance (health, dental, life, disability), 401k with company match, PTO, relocation assistance and occurrence-based malpractice insurance coverage
See how you can thrive, right here at Indiana University Health
Community Description
Indianapolis, Indiana, the 17th largest U.S. city, is a sophisticated city blending charm and culture with a wonderful balance of business and leisure. Residents of this dynamic city enjoy:
- Leading educational system and top-ranked universities, paired with a diverse population
- Vibrant downtown offering arts, theaters, world-class museums, zoo, concerts and memorials
- Named to U.S. News & World Report's 2023-2024 list of the best places to live in the United States
- Top ranked international airport: "Best Airport in North America" twelve consecutive years
- Ranked by Niche in 2023 as one of the most diverse counties in America, as well as one of the best cities to live in and buy a house in the country
- Historic neighborhoods with surrounding cultural districts and low cost of living
- Outdoor recreation includes golfing, boating and unique parks
- Home of the Colts (NFL), Fever (WNBA), Pacers (NBA), Indians (MiLB), Indianapolis 500 (IndyCar) and the nation's largest half marathon
- Close proximity to Chicago, St. Louis, Louisville, and Cincinnati
Healthcare System/Hospital Description
IU Health Methodist Hospital is a regional healthcare leader through its commitment to excellence, accessibility and preeminence. Part of the IU Health Adult Academic Health Center, it is currently ranked by U.S. News & World Report as the top hospital in the state of Indiana, with 13 procedures/conditions rated as high performing.
With 1,000 beds, IU Health Methodist Hospital is a large tertiary referral center with over 130 ICU beds. It serves as the largest trauma center in Indianapolis, as well as a highly subspecialized center for cardiovascular surgery, thoracic surgery, neurosurgery, lung transplantation, and neurocritical care.
IU Health is building a new downtown hospital and campus, which will consolidate operations of the adjacent IU Health Methodist and University Hospitals. Construction for the new hospital is well underway and set to open in late 2027. It will feature three 16-story towers with 864 beds. IU School of Medicine is also constructing a medical education and research building directly east of the new hospital.
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Who's Hiring
- Indiana University Health34

- Ascension6

- HarmonyCares6

- Legion Health6

- State of Indiana6

NP Jobs in Indianapolis: Frequently Asked Questions
How do I get a np job in Indianapolis?
The strongest path into Indianapolis np roles is through its large health systems, which run the most active hiring pipelines in the city. Concentrating your search on the IU Health, Eskenazi Health, and Franciscan Health networks gives you the broadest exposure to open positions. Candidates with specialty certifications in family practice, psychiatry, or acute care tend to move fastest in this market, where primary care and behavioral health demand is especially high.
Which companies hire nps in Indianapolis?
Companies currently hiring nps in Indianapolis include Indiana University Health, Ascension, and HarmonyCares, per current listings on Migrate Mate as of August 2026. Indianapolis draws from a mix of large academic medical centers, community health organizations, and multispecialty clinic groups, giving nps a range of practice environments to choose from.
Are there remote np jobs in Indianapolis?
Yes, though remote opportunities are limited for nps since the role is inherently hands-on and patient-facing. About 74% of np openings tied to Indianapolis are remote or hybrid as of August 2026, which is below average for professional roles. When remote work does appear, it tends to be in telehealth urgent care or care management positions rather than primary clinical practice.
How can I get a np job in Indianapolis with little or no experience?
The most realistic entry path in Indianapolis is through new graduate residency and fellowship programs, several of which are offered by the city's major health systems. Community health centers and federally qualified health centers in Indianapolis also tend to hire new graduates at a higher rate than private practices. Targeting np roles within urgent care networks and retail clinic operators downtown can also provide early clinical hours and a foothold into Indianapolis's broader healthcare market.
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