NP Jobs in Greenville, SC

NP jobs in Greenville, South Carolina concentrate in the Haywood Road medical corridor, downtown Greenville, and the Eastside near Prisma Health and Bon Secours facilities, with strong demand in primary care, urgent care, and behavioral health. Employers hiring right now include Prisma Health, Prisma Health Urgent Care, and CVS Health. Find a role that fits below and apply directly.

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Overview

Open roles39
Top employerPrisma Health
Work type92% On-site
Top credentialMaster's
Companies hiring20

Showing 5 of 39+ NP jobs

Curana Health
Nurse Practitioner - Psychiatric
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Curana Health
New 1m ago
Nurse Practitioner - Psychiatric
Curana Health
Greenville, South Carolina
Business Analysis
Data Analytics
Project Management
BLS Certification
1,001-5,000

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HarmonyCares
PRN Nurse Practitioner Per Visit in Greenville, SC
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HarmonyCares
New 1m ago
PRN Nurse Practitioner Per Visit in Greenville, SC
HarmonyCares
Greenville, South Carolina
Healthcare Administration
Nursing
Patient Services & Wellbeing
Remote (US)
BLS Certification
1,001-5,000

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Comprehensive Rehab Consultants
Nurse Practitioner
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Comprehensive Rehab Consultants
New 1m ago
Nurse Practitioner
Comprehensive Rehab Consultants
Greenville, South Carolina
Healthcare Administration
Nursing
Patient Services & Wellbeing
51-200

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Prisma Health
Nurse Practitioner –Geriatrics PACE Greenville – PRN
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Prisma Health
New 1m ago
Nurse Practitioner –Geriatrics PACE Greenville – PRN
Prisma Health
Greenville, South Carolina
Allied Health
Healthcare Administration
Nursing
Master's degree in nursing
10,000+

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Carolinas Fertility Institute
Advanced Practice Provider
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Carolinas Fertility Institute
New 1m ago
Advanced Practice Provider
Carolinas Fertility Institute
Greenville, South Carolina
Healthcare Administration
Nursing
Patient Services & Wellbeing
On-Site
Master's degree
51-200

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See All 39 NP Jobs in Greenville

Find roles in Greenville that match your experience and apply in just a few clicks.

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NP Job Market in Greenville

Who's Hiring

  • Prisma Health
    Prisma Health19
  • P
    Prisma Health Urgent Care2
  • CVS Health
    CVS Health1
  • Crossroads
    Crossroads1
  • DOCS Health
    DOCS Health1

Top Industries Hiring

  • Healthcare & Medical Services19
  • Consulting & Professional Services4

NP Jobs in Greenville: Frequently Asked Questions

How do I get a np job in Greenville?

Greenville's largest np employers are health systems, multispecialty physician groups, and federally qualified health centers serving the Upstate region. Roles concentrate along the Haywood Road corridor, in the downtown medical district, and on the Eastside near major hospital campuses. Candidates with primary care, behavioral health, or urgent care experience move fastest here. Tailoring your application to the Upstate patient population and showing familiarity with Epic or Athenahealth gives you a concrete edge.

Which companies hire nps in Greenville?

Greenville np roles are posted by Prisma Health, Prisma Health Urgent Care, and CVS Health and others right now, based on current listings on Migrate Mate as of July 2026. The local market is anchored by large health systems alongside independent physician groups and community health clinics that serve Greenville County's growing and diverse population.

Are there remote np jobs in Greenville?

Yes, though most np roles require hands-on patient care and are therefore on-site. About 8% of np openings tied to Greenville are remote or hybrid as of July 2026, covering positions in telehealth, utilization review, and chronic disease management. Behavioral health and some specialty consultation roles in Greenville are the most likely to offer fully remote or hybrid arrangements.

How can I get a np job in Greenville with little or no experience?

The most realistic entry path in Greenville is through new-graduate NP programs at Prisma Health or Bon Secours, which offer structured residencies and fellowships for clinicians transitioning from RN roles. Community health centers and urgent care groups in the Upstate region also hire new grads, particularly in primary care and family medicine. Completing clinical rotations at Greenville-area facilities and building relationships with local preceptors significantly improves your chances of landing your first position here.

Which industries hire the most nps in Greenville?

Greenville np roles concentrate in Healthcare & Medical Services and Consulting & Professional Services, based on current listings on Migrate Mate as of July 2026. Greenville's position as the healthcare hub of the South Carolina Upstate, combined with rapid population growth and an expanding network of outpatient clinics, continues to drive consistent demand across these sectors.

See All 39 NP Jobs in Greenville

Find roles in Greenville that match your experience and apply in just a few clicks.

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