NP Jobs in South Carolina
NP jobs in South Carolina are concentrated in Columbia, Charleston, and Greenville, where major health systems like Prisma Health, MUSC Health, and Bon Secours St. Francis actively recruit across primary care, psychiatry, and acute care. Demand reaches from new graduate NPs entering federally qualified health centers to seasoned practitioners taking on autonomous practice roles under South Carolina's full-practice authority law. Family practice and urgent care posts see the most consistent volume statewide. Find a role that fits below and apply directly.
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Position - Nurse Practitioners! License needed in SC, VA, GA
Remote Care Partners
Remote Care Partners is seeking a compassionate, experienced, and self-motivated Nurse Practitioner (APRN) to join our growing virtual care team. This is a fully remote position offering flexibility to provide high-quality patient care from anywhere while making a meaningful impact on patient outcomes through innovative healthcare technology.
The ideal candidate is passionate about preventive care, chronic disease management, weight management, and patient engagement. This role combines clinical care delivery with ongoing oversight of patients enrolled in Remote Patient Monitoring (RPM), Chronic Care Management (CCM), and weight management programs.
What You'll Do: Responsibilities include, but are not limited to:
- Conduct virtual primary care visits for adult patients
- Perform Remote Patient Monitoring (RPM) and Chronic Care Management (CCM) visits
- Conduct weight management consultations and follow-up appointments
- Conduct primary care appointments for acute illnesses, refills, etc.
- Provide ongoing clinical oversight and management of RPM, CCM, and weight management patient populations
- Collaborate with nurses, care coordinators, specialists, pharmacists, and other healthcare professionals to optimize patient outcomes
- Educate patients on disease prevention, lifestyle modification, medication adherence, and self-management strategies
- Ensure compliance with Medicare, payer, state, and organizational guidelines
- Participate in quality improvement initiatives and population health management efforts
Requirements:
- MUST HAVE Active, unrestricted APRN license in good standing in South Carolina, Virginia, and/or Georgia.
- Additional licensure in Mississippi and Alabama preferred.
- Minimum of 3 years of Nurse Practitioner experience
- Experience in primary care, chronic disease management, obesity medicine, telehealth, or population health preferred
- Comfortable delivering care through telehealth platforms and documenting within EHR systems
- Strong clinical assessment, communication, and organizational skills
- Ability to work independently while collaborating effectively with a multidisciplinary team
- Proficiency with technology and remote patient monitoring tools
Benefits & Perks:
- Full-time, salaried position; part-time possibility
- 100% remote work environment
- Regular practice hours maintained
- Comprehensive benefits package available
- Company-provided software and hardware
- Malpractice insurance provided
- Ongoing training and professional development opportunities
- Collaborative and supportive care team
- Opportunity to help shape the future of virtual healthcare
- Additional state licenses are encouraged, and licensure costs will be reimbursed after licensure is obtained.
Who We Are: Remote Care Partners (RCP)
At Remote Care Partners, we're redefining healthcare through innovative virtual care solutions. Our cloud-based platform delivers Remote Patient Monitoring (RPM), Chronic Care Management (CCM), patient engagement, population health services, telemedicine, and preventive care programs designed to keep patients healthier between office visits.
We empower healthcare professionals to provide exceptional patient-centered care through technology-driven solutions that improve outcomes, increase engagement, and enhance quality of life.
Join Our Team & Change Lives!
If you're a dedicated Nurse Practitioner who thrives in a technology-enabled, patient-first environment and is passionate about improving healthcare accessibility, we'd love to hear from you.
Apply today and become a vital part of our innovative and growing virtual care team.
See All 81 NP Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find NP JobsNP Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
NP Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring
- Prisma Health Urgent Care12P
- Your Health Organization9

- CVS Health3

- Lowcountry Urgent Care3
- Armor Health2

Top Industries Hiring
- Insurance
- Healthcare & Medical Services
What South Carolina Employers Look For
The qualifications that appear most often in NP jobs across South Carolina.
- Active NP license issued or recognized by the South Carolina Board of Nursing
- Current national certification from AANP, ANCC, or other accredited certifying body
- Master of Science in Nursing or Doctor of Nursing Practice from an accredited program
- Current and unencumbered RN license in South Carolina or a Nurse Licensure Compact state
- Current BLS certification and ACLS certification for acute care or emergency settings
- One or more years of clinical experience in a relevant NP specialty or patient population
NP Jobs in South Carolina: Frequently Asked Questions
How do you become a np in South Carolina?
To become an NP in South Carolina, you must hold a current RN license issued or recognized by the South Carolina Board of Nursing, complete a graduate-level NP program, and obtain national certification from a body such as AANP or ANCC. You then apply for advanced practice registered nurse licensure through the South Carolina Board of Nursing. South Carolina recognizes full practice authority for NPs, so no physician collaboration agreement is required once licensed.
Which companies hire nps in South Carolina?
Employers hiring nps in South Carolina right now include Prisma Health Urgent Care, Your Health Organization, and CVS Health, based on current listings on Migrate Mate as of October 2026. South Carolina's largest systems, including Prisma Health and MUSC Health, maintain consistent pipelines for primary care, behavioral health, and specialty NP roles across both urban medical centers and rural outpatient clinics.
Which South Carolina cities have the most np jobs?
Columbia, Charleston, and Anderson lead South Carolina for np openings. Columbia anchors the market as the state capital and home to Prisma Health's flagship campuses, while Charleston draws heavy volume from MUSC Health and a dense network of outpatient and specialty practices, and Greenville reflects the fast-growing Upstate corridor where Bon Secours St. Francis and large urgent care groups are expanding NP staffing.
Are there remote np jobs in South Carolina?
Yes, but they're rare. About 44% of np openings tied to South Carolina are remote or hybrid as of October 2026, reflecting the hands-on nature of most clinical NP work. The positions most likely to offer remote or hybrid arrangements are those focused on telehealth primary care, behavioral health counseling, or utilization review, where patient encounters happen via video platform rather than in person.
How can I get hired as a np in South Carolina with little or no experience?
The most realistic entry path is a new-graduate NP residency or fellowship program, and both Prisma Health and MUSC Health run structured transition-to-practice programs that prioritize candidates without post-graduate NP experience. Federally qualified health centers operating across rural South Carolina counties also hire new graduates specifically to fill primary care gaps. Coming from an RN background in a relevant specialty, such as ICU or emergency nursing, strengthens an application considerably, as does completing clinical hours at the hiring facility during your NP program.
Where can I find and apply to np jobs in South Carolina?
You can find and apply to np jobs in South Carolina on Migrate Mate, which lists current South Carolina openings updated regularly. Search the listings, find roles that match your specialty and preferred location, and apply directly to the employers posting them. No sign-up is required to see the openings.
See All 81 NP Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
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