Practice Assistant Jobs in South Carolina
Practice assistant jobs in South Carolina are consistently active, with demand concentrated in healthcare practice management, dental and medical offices, and veterinary clinics at both entry-level and experienced tiers. Columbia, Greenville, and Charleston drive the largest share of openings, where employers such as Prisma Health, MUSC Health, and Palmetto Primary Care Physicians regularly staff these roles. The most in-demand specialties include medical practice administration, dental assisting support, and front-office clinical coordination. Scan the live roles below and apply to whichever ones fit.
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- High school diploma required.
- Two (2) years previous customer service/administrative clerical experience required.
- Prior experience working front desk operations in healthcare preferred.
- Insurance Billing and Coding Specialist (CBCS) Certification preferred.
- Medical Administrative Assistant (CMAA) Certification preferred.
- CRMA certification or Billing/Coding Certification preferred.
- Greet all patients and their accompanying family members when applicable and provide exemplary customer service.
- Responsible for scheduling patient’s appointments, adjust scheduling for emergency cases, obtaining insurance verification and authorization, and updating and maintaining electronic medical records.
- Assist with the billing for physicians’ offices, such as processing insurance claim forms, patient and insurance billing data gathering, medical billing and coding, collections, and accounts receivable and payable.
- Work effectively and collaboratively with colleagues, physicians, department heads, and leadership members.
- Effectively utilize strong organizational skills.
- Consistently display effective verbal and written communication skills.
- Proficient use of Microsoft Outlook, Word, Excel, Explorer, and PowerPoint.
- Remain calm and professional in all situations.
- Each employee who participates in the coding, billing or claims submission process, from the initial receipt of a physician order to the receipt of payment for services, shall accurately and honestly perform his/her functions to ensure that accurate claims are submitted, and the organization retains only those funds to which it is legally entitled.
- Part of a centralized medical office and will complete any duties needed to help the office function for which the employee is competent.
- Will complete other duties as assigned.
- High school diploma required.
- Two (2) years previous customer service/administrative clerical experience required.
- Prior experience working front desk operations in healthcare preferred.
- Insurance Billing and Coding Specialist (CBCS) Certification preferred.
- Medical Administrative Assistant (CMAA) Certification preferred.
- CRMA certification or Billing/Coding Certification preferred.
- Greet all patients and their accompanying family members when applicable and provide exemplary customer service.
- Responsible for scheduling patient’s appointments, adjust scheduling for emergency cases, obtaining insurance verification and authorization, and updating and maintaining electronic medical records.
- Assist with the billing for physicians’ offices, such as processing insurance claim forms, patient and insurance billing data gathering, medical billing and coding, collections, and accounts receivable and payable.
- Work effectively and collaboratively with colleagues, physicians, department heads, and leadership members.
- Effectively utilize strong organizational skills.
- Consistently display effective verbal and written communication skills.
- Proficient use of Microsoft Outlook, Word, Excel, Explorer, and PowerPoint.
- Remain calm and professional in all situations.
- Each employee who participates in the coding, billing or claims submission process, from the initial receipt of a physician order to the receipt of payment for services, shall accurately and honestly perform his/her functions to ensure that accurate claims are submitted, and the organization retains only those funds to which it is legally entitled.
- Part of a centralized medical office and will complete any duties needed to help the office function for which the employee is competent.
- Will complete other duties as assigned.
See All 15 Practice Assistant Jobs in South Carolina
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Find Practice Assistant JobsPractice Assistant Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Practice Assistant Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring
Top Industries Hiring
- Education
- Law & Legal Services
- Healthcare & Medical Services
What South Carolina Employers Look For
The qualifications that appear most often in practice assistant jobs across South Carolina.
- Active South Carolina medical or dental assistant registration or applicable state credential recognized in South Carolina
- Minimum one year of experience in a clinical or medical office setting
- Proficiency with electronic health record systems such as Epic or Athenahealth
- Strong knowledge of medical billing, coding, and insurance verification procedures
- Ability to perform front-desk and patient intake duties in a fast-paced practice environment
- Excellent written and verbal communication skills for patient and provider interaction
Practice Assistant Jobs in South Carolina: Frequently Asked Questions
How do you become a practice assistant in South Carolina?
Most practice assistant positions in South Carolina require a high school diploma or GED plus a recognized credential such as a Certified Medical Assistant credential through the American Association of Medical Assistants or a Certified Clinical Medical Assistant designation. South Carolina does not maintain a single state licensing board for practice assistants, but many employers require proof of certification and familiarity with state-specific healthcare compliance rules. Completing a medical assisting or health administration program at a South Carolina technical college strengthens your application considerably.
Which companies hire practice assistants in South Carolina?
South Carolina practice assistant roles are posted by Conway Medical Center, RevCats, and Bon Secours and others right now, based on current listings on Migrate Mate as of October 2026. Large health systems and multi-site specialty practices across the Midlands and Upstate regions tend to post the most consistent volume throughout the year.
Which South Carolina cities have the most practice assistant jobs?
Charleston, Spartanburg, and Conway account for the most practice assistant openings in South Carolina. Columbia leads because of the large concentration of state government health programs and major hospital systems headquartered there, while Greenville and Charleston drive volume through fast-growing health systems and the expanding suburban medical campuses that have developed around both metros in recent years.
Are there remote practice assistant jobs in South Carolina?
Yes, but they're rare. Practice assistant work is largely on-site because it involves direct patient contact, front-desk coordination, and hands-on administrative support within a clinical setting. About 0% of practice assistant openings tied to South Carolina are remote or hybrid as of October 2026, and those tend to cluster in billing, prior authorization, and insurance coordination functions that do not require a physical presence.
How can I get hired as a practice assistant in South Carolina with little or no experience?
The most realistic entry path is applying for a front-office medical receptionist or patient services representative role at a large South Carolina health system such as Prisma Health or MUSC Health, both of which run structured new-hire onboarding programs. Completing a medical assisting certificate at a South Carolina Technical College System campus gives you the credential most employers look for. Lateral moves from adjacent roles like pharmacy technician or dental receptionist are also common stepping stones into practice assistant positions across the state.
Where can I find and apply to practice assistant jobs in South Carolina?
You can find and apply to practice assistant jobs in South Carolina on Migrate Mate, which lists current South Carolina openings updated in real time. Search the listings, find the roles that match your experience and preferred location, and apply directly to the ones that fit.
See All 15 Practice Assistant Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
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