Practice Assistant Jobs in South Carolina
Practice assistant jobs in South Carolina are consistently active, with demand concentrated in healthcare practice management, dental and medical offices, and veterinary clinics at both entry-level and experienced tiers. Columbia, Greenville, and Charleston drive the largest share of openings, where employers such as Prisma Health, MUSC Health, and Palmetto Primary Care Physicians regularly staff these roles. The most in-demand specialties include medical practice administration, dental assisting support, and front-office clinical coordination. Scan the live roles below and apply to whichever ones fit.
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Summary
Responsible for providing legal secretarial and administrative support for the Practice Group.
Essential Job Functions
- Prepare correspondence, memoranda and other legal documents such as summonses, complaints, motions, responses, and subpoenas under the supervision of an attorney or other timekeepers
- Provide trial support
- Formatting briefs, pleadings and other legal documents
- Keeping track of attorney time records and billing
- Filing legal documents (e-filling skills are required)
- Transcribing dictation
- Corresponding with clients
- Maintaining calendars
- Open new files and client matters
- Request conflict of interest checks
- Maintain all client and general files
- Maintain client contact when appropriate
- Work closely with other administrative support staff (conflicts, records, office services, etc.)
- Receive clients and visitors; maintains good public relations with clients; observes confidentiality of attorney-client relationship
- Proof read documents
Necessary Knowledge, Skills and Abilities
- Excellent interpersonal and organizational skills and the ability to work successfully with multiple team members, interacting with employees at all levels of the organization.
- Competent to handle a variety of activities with attention to detail and quality, with the ability to follow through and follow up, and adapt to quickly meet changing deadlines and priorities.
- Advanced proficiency with Microsoft Office Suite applications, including Word, Excel, and Outlook.
- Ability to complete multiple tasks and a high volume of work on short deadlines and follow through on assigned tasks with limited supervision.
- Retain a high level of flexibility and resourceful problem solving.
- Exceptional verbal and written communication skills.
- Ability to handle sensitive information with the highest degree of integrity and confidentiality.
Educational and Experience Requirements
- High School diploma required
- Prior litigation experience required
- Associate’s degree preferred
- Paralegal Certificate preferred
Work Environment and Physical Demands
- In office position
- Ability to work extended hours when necessary.
- Normal office environment; no unusual physical demands.
See All 6 Practice Assistant Jobs in South Carolina
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Find Practice Assistant JobsPractice Assistant Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Practice Assistant Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring


Top Industries Hiring
- Healthcare & Medical Services
What South Carolina Employers Look For
The qualifications that appear most often in practice assistant jobs across South Carolina.
- Active South Carolina medical or dental assistant registration or applicable state credential recognized in South Carolina
- Minimum one year of experience in a clinical or medical office setting
- Proficiency with electronic health record systems such as Epic or Athenahealth
- Strong knowledge of medical billing, coding, and insurance verification procedures
- Ability to perform front-desk and patient intake duties in a fast-paced practice environment
- Excellent written and verbal communication skills for patient and provider interaction
Practice Assistant Jobs in South Carolina: Frequently Asked Questions
How do you become a practice assistant in South Carolina?
Most practice assistant positions in South Carolina require a high school diploma or GED plus a recognized credential such as a Certified Medical Assistant credential through the American Association of Medical Assistants or a Certified Clinical Medical Assistant designation. South Carolina does not maintain a single state licensing board for practice assistants, but many employers require proof of certification and familiarity with state-specific healthcare compliance rules. Completing a medical assisting or health administration program at a South Carolina technical college strengthens your application considerably.
Which companies hire practice assistants in South Carolina?
South Carolina practice assistant roles are posted by Prisma Health, Carolina Nephrology, PA, and Bon Secours and others right now, based on current listings on Migrate Mate as of August 2026. Large health systems and multi-site specialty practices across the Midlands and Upstate regions tend to post the most consistent volume throughout the year.
Which South Carolina cities have the most practice assistant jobs?
Greenville, Easley, and Charleston account for the most practice assistant openings in South Carolina. Columbia leads because of the large concentration of state government health programs and major hospital systems headquartered there, while Greenville and Charleston drive volume through fast-growing health systems and the expanding suburban medical campuses that have developed around both metros in recent years.
How can I get hired as a practice assistant in South Carolina with little or no experience?
The most realistic entry path is applying for a front-office medical receptionist or patient services representative role at a large South Carolina health system such as Prisma Health or MUSC Health, both of which run structured new-hire onboarding programs. Completing a medical assisting certificate at a South Carolina Technical College System campus gives you the credential most employers look for. Lateral moves from adjacent roles like pharmacy technician or dental receptionist are also common stepping stones into practice assistant positions across the state.
Where can I find and apply to practice assistant jobs in South Carolina?
You can find and apply to practice assistant jobs in South Carolina on Migrate Mate, which lists current South Carolina openings updated in real time. Search the listings, find the roles that match your experience and preferred location, and apply directly to the ones that fit.
See All 6 Practice Assistant Jobs in South Carolina
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