Licensed Practical Nurse Jobs in South Carolina
Licensed Practical Nurse jobs in South Carolina concentrate in long-term care, hospital systems, and correctional health, with steady demand from entry-level to charge supervision across the state. Columbia, Greenville, and Charleston lead hiring activity, anchored by employers like Prisma Health, MUSC Health, and Grand Strand Medical Center. The highest-demand specialties are geriatric care, med-surg, and behavioral health. See the openings below and apply to the ones that match your experience.
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JOB TITLE: LPN
DEPARTMENT: Nursing
REPORTS TO: RN Supervisor or Director of Nursing
DIRECT REPORTS: CNAs
FLSA STATUS: Non-Exempt/Hourly
DATE: 08/24/26
JOB SUMMARY
A Licensed Practical Nurse (LPN) provides care and treatment in accordance with physician orders. Works in a team environment and within scope of practice as defined by State. The LPN works under the direction of physicians and Registered Nurses (RNs).
JOB QUALIFICATIONS
- Graduate of an accredited school of Nursing
- Valid State licensure as an LPN
- Current CPR certification
ESSENTIAL DUTIES AND RESPONSIBILITIES
- Assesses patients by physical examination, including pertinent diagnostic testing to determine health status.
- Administers medications and treatments
- Participates in the care planning process
- Supervises Nursing Assistants, oversees ADLs and documentation
- Communicates with physicians regarding changes in resident's conditions, diagnostic test results, etc.
- Documents assessments and care in compliance with standards of care and company policy.
- Educates patients and their families on health-related issues.
- Completes required forms and documents in accordance with company policy and state and/or federal regulations.
- Other duties as assigned.
OTHER REQUIREMENTS
Participates in (or conducts) company-sponsored training to safeguard against improper use and disclosure of resident's protected health information. Monitors and ensures compliance with company policies, procedures and state and federal law.
PHYSICAL DEMANDS AND ENVIRONMENT
Shift work may be required. Employee is occasionally exposed to blood or other body fluids, fumes or airborne particles and toxic or caustic chemicals. In compliance with applicable law, reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions of the position.
Standing - Frequently
Sitting - Occasionally
Walking - Frequently
Use Hands/Fingers to handle or feel - Frequently
Climbing or Balance - Occasionally
Stoop, Kneel, Crouch, or Crawl - Occasionally
Talk/Hear - Frequently
See - Frequently
Taste/Smell - Occasionally
Reaching/Pulling/Pushing - Frequently
Carry Weight/Lift - Occasionally
Benefits:
- 401(k)
- Dental insurance
- Flexible spending account
- Health insurance
- Health savings account
- Life insurance
- Paid time off
- Vision insurance
Work Location: In person
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Find Licensed Practical Nurse JobsLicensed Practical Nurse Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Licensed Practical Nurse Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring
- BAYADA Home Health Care19

- PruittHealth8

- Angels of Care Pediatric Home Health6

- OneWell Health Care5

- Chandler Creek Post Acute5C
Top Industries Hiring
- Healthcare & Medical Services
What South Carolina Employers Look For
The qualifications that appear most often in licensed practical nurse jobs across South Carolina.
- Active Licensed Practical Nurse license issued or recognized by the South Carolina Board of Nursing
- Graduate of a state-approved practical nursing program with NCLEX-PN passage
- Minimum one year of clinical experience in a long-term care or acute care setting
- Current BLS or CPR certification from an accredited provider
- Proficiency in electronic health records documentation and medication administration
- Strong communication skills and ability to work rotating or weekend shifts
Licensed Practical Nurse Jobs in South Carolina: Frequently Asked Questions
How do you become a licensed practical nurse in South Carolina?
You become a licensed practical nurse in South Carolina by completing a state-approved practical nursing program, passing the NCLEX-PN exam, and applying for licensure through the South Carolina Board of Nursing. Programs are available at technical colleges throughout the state, including Midlands Technical College and Greenville Technical College. Once licensed, you may also apply through endorsement if you hold an active LPN license from another state.
How much do licensed practical nurses make in South Carolina?
Licensed practical nurses in South Carolina earn a median of about $61,820 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $50,370 for the lowest 10% to over $76,420 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire licensed practical nurses in South Carolina?
Employers hiring licensed practical nurses in South Carolina right now include BAYADA Home Health Care, PruittHealth, and Angels of Care Pediatric Home Health, based on current listings on Migrate Mate as of August 2026. Large health systems like Prisma Health and MUSC Health, along with long-term care networks and correctional health contractors, consistently post LPN openings across South Carolina's major metros and rural counties.
Which South Carolina cities have the most licensed practical nurse jobs?
Greer, Columbia, and Mount Pleasant have the most licensed practical nurse openings in South Carolina. Columbia leads as the state capital and home to major systems like Prisma Health, while Charleston's medical district anchors demand in the Lowcountry and Greenville's growing hospital network drives consistent hiring in the Upstate region.
Are there remote licensed practical nurse jobs in South Carolina?
Yes, but they're rare. About 0% of licensed practical nurse openings tied to South Carolina are remote or hybrid as of August 2026, reflecting the hands-on, bedside nature of most LPN work. The narrow exceptions include telephone triage roles and care coordination positions that some larger South Carolina health systems have moved to a hybrid model.
How can I get hired as a licensed practical nurse in South Carolina with little or no experience?
The most realistic entry path is applying directly to long-term care facilities and skilled nursing facilities, which tend to hire new LPN graduates before hospital systems do. Employers like PruittHealth and Agape Care, which operate across South Carolina, regularly onboard new graduates. Completing a clinical rotation at a South Carolina technical college and holding current NCLEX-PN licensure through the South Carolina Board of Nursing gives candidates the strongest edge. Certified nursing assistant experience is a common and recognized stepping stone.
Where can I find and apply to licensed practical nurse jobs in South Carolina?
You can find and apply to licensed practical nurse jobs in South Carolina on Migrate Mate, which lists current openings from employers across the state. Search the listings to find roles that match your experience level, preferred location, and setting, then apply directly to the ones that fit.
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