Licensed Practical Nurse Jobs in South Carolina

Licensed Practical Nurse jobs in South Carolina are open across Charleston, Columbia, and Greenville and other South Carolina metros, with employers like Medical University of South Carolina, OneWell Health Care, and McLeod Health hiring at every experience level. Find a role that fits below and apply directly.

Find Licensed Practical Nurse Jobs

Overview

Open roles219+
Top cityCharleston, SC
Cities hiring80
Work type99% On-site
Top industryHealthcare

Showing 5 of 219+ Licensed Practical Nurse jobs

Prisma Health
Licensed Practical Nurse
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Prisma Health
New 2h ago
Licensed Practical Nurse
Prisma Health
Greenville, South Carolina
Nursing
Healthcare Administration
Patient Services & Wellbeing
On-Site
Associate's
10,000+

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McLeod Health
Lpn
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McLeod Health
New 4h ago
Lpn
McLeod Health
Dillon, South Carolina
Nursing
Healthcare Administration
Patient Services & Wellbeing
Caregiving & Elderly Support
Remote (US)
None
10,000+

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Prisma Health
Licensed Practical Nurse (LPN)
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Prisma Health
Added 3d ago
Licensed Practical Nurse (LPN)
Prisma Health
Greenville, South Carolina
Nursing
Healthcare Administration
Patient Services & Wellbeing
On-Site
Associate's
10,000+

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Prisma Health
Licensed Practical Nurse
We won't show you this job again
Prisma Health
Added 3d ago
Licensed Practical Nurse
Prisma Health
Seneca, South Carolina
Nursing
Healthcare Administration
Patient Services & Wellbeing
On-Site
Associate's
10,000+

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Prisma Health
Licensed Practical Nurse
We won't show you this job again
Prisma Health
Added 3d ago
Licensed Practical Nurse
Prisma Health
Greenville, South Carolina
Nursing
Healthcare Administration
Patient Services & Wellbeing
On-Site
Associate's
10,000+

Have you applied for this role?

See All 219+ Licensed Practical Nurse Jobs in South Carolina

Find roles in South Carolina that match your experience and apply in just a few clicks.

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Licensed Practical Nurse Jobs by City in South Carolina

Where South Carolina roles are concentrated, by current openings.

Charleston
17 jobs
Columbia
15 jobs
Greenville
15 jobs
Florence
11 jobs
Sumter
8 jobs
Lancaster
7 jobs
Little River
7 jobs
West Columbia
6 jobs
Anderson
5 jobs

Licensed Practical Nurse Job Market in South Carolina

A snapshot from current South Carolina openings, updated as new roles post.

Who's Hiring

  • Medical University of South Carolina
    Medical University of South Carolina55
  • OneWell Health Care
    OneWell Health Care28
  • McLeod Health
    McLeod Health25
  • PruittHealth
    PruittHealth25
  • National HealthCare Corporation
    National HealthCare Corporation19

Top Industries Hiring

  • Healthcare & Medical Services185
  • Education35
  • Biotechnology & Pharmaceuticals3
  • Consulting & Professional Services3
  • Government & Public Sector1

What South Carolina Employers Look For

The qualifications that appear most often in licensed practical nurse jobs across South Carolina.

  • Active LPN or LVN state license in good standing
  • Completion of an accredited practical nursing program
  • Current CPR and Basic Life Support certification
  • Experience with electronic health records documentation
  • Ability to perform wound care, IV therapy, and medication administration
  • Strong patient assessment and vital signs monitoring skills

Licensed Practical Nurse Jobs in South Carolina: Frequently Asked Questions

How many licensed practical nurse jobs are there in South Carolina?

There are 219+ licensed practical nurse openings in South Carolina on Migrate Mate as of June 2026, with the most roles in Charleston, Columbia, and Greenville. New positions post regularly as employers across South Carolina hire.

How much do licensed practical nurses make in South Carolina?

Licensed practical nurses in South Carolina earn a median of about $61,820 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $50,370 for the lowest 10% to over $76,420 for the top 10%. Pay rises with experience, specialty, and employer.

Which South Carolina cities have the most licensed practical nurse jobs?

Charleston, Columbia, and Greenville have the most licensed practical nurse openings in South Carolina right now, with additional roles spread across smaller metros statewide.

Which companies hire licensed practical nurses in South Carolina?

Employers hiring licensed practical nurses in South Carolina include Medical University of South Carolina, OneWell Health Care, and McLeod Health, based on current listings on Migrate Mate as of June 2026.

Are there remote licensed practical nurse jobs in South Carolina?

Yes. About 1% of licensed practical nurse openings tied to South Carolina are remote or hybrid as of June 2026. The rest are on-site roles based in South Carolina metros.

How do I apply for licensed practical nurse jobs in South Carolina?

You can apply to licensed practical nurse jobs in South Carolina directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred South Carolina location, then apply to each one that fits.

See All 219+ Licensed Practical Nurse Jobs in South Carolina

Find roles in South Carolina that match your experience and apply in just a few clicks.

Find Licensed Practical Nurse Jobs