Licensed Practical Nurse Jobs in South Carolina

Licensed Practical Nurse jobs in South Carolina concentrate in long-term care, hospital systems, and correctional health, with steady demand from entry-level to charge supervision across the state. Columbia, Greenville, and Charleston lead hiring activity, anchored by employers like Prisma Health, MUSC Health, and Grand Strand Medical Center. The highest-demand specialties are geriatric care, med-surg, and behavioral health. See the openings below and apply to the ones that match your experience.

Find Licensed Practical Nurse Jobs

Overview

Open roles94
Top employerBAYADA Home Health Care
Top cityGreer, SC
Cities hiring53
Work type100% On-site
Top industryHealthcare

Showing 5 of 94+ Licensed Practical Nurse jobs

South Carolina Health Care Association
LPN
We won't show you this job again
South Carolina Health Care Association
Added 1d ago
LPN
South Carolina Health Care Association
Sumter, South Carolina
Account Management
Business Development
Sales
On-Site
CPR Certification
201-500

Have you applied for this role?

Doctors Care
Greer Certified Medical Assistant/ LPN PRN
We won't show you this job again
Doctors Care
Added 1d ago
Greer Certified Medical Assistant/ LPN PRN
Doctors Care
Greer, South Carolina
IT Support
Project Management
Technical Program Management
CPR Certification
1,001-5,000

Have you applied for this role?

Kindred Hospitals
LPN - Clinic
We won't show you this job again
Kindred Hospitals
Added 1d ago
LPN - Clinic
Kindred Hospitals
Hartsville, South Carolina
Healthcare Administration
Patient Services & Wellbeing
Social Work & Counseling
Managed Registered Nurses (RNs)
10,000+

Have you applied for this role?

McCormick Post Acute
LPN
We won't show you this job again
McCormick Post Acute
Added 1d ago
LPN
McCormick Post Acute
McCormick, South Carolina
Healthcare Administration
Patient Services & Wellbeing
Social Work & Counseling
$30 - $34/hr
On-Site

Have you applied for this role?

Edisto Post Acute
LPN Part Time
We won't show you this job again
Edisto Post Acute
Added 1d ago
LPN Part Time
Edisto Post Acute
Orangeburg, South Carolina
Healthcare Administration
Patient Services & Wellbeing
Social Work & Counseling
$30 - $34/hr
On-Site

Have you applied for this role?

See All 94 Licensed Practical Nurse Jobs in South Carolina

Find roles in South Carolina that match your experience and apply in just a few clicks.

Find Licensed Practical Nurse Jobs

Licensed Practical Nurse Jobs by City in South Carolina

Where South Carolina roles are concentrated, by current openings.

Greer
7 jobs
Columbia
5 jobs
Mount Pleasant
5 jobs
Fort Mill
4 jobs
Rock Hill
3 jobs
Orangeburg
3 jobs
Simpsonville
3 jobs
Conway
2 jobs
Easley
2 jobs

Licensed Practical Nurse Job Market in South Carolina

A snapshot from current South Carolina openings, updated as new roles post.

Who's Hiring

  • BAYADA Home Health Care
    BAYADA Home Health Care19
  • PruittHealth
    PruittHealth8
  • Angels of Care Pediatric Home Health
    Angels of Care Pediatric Home Health6
  • OneWell Health Care
    OneWell Health Care5
  • C
    Chandler Creek Post Acute5

Top Industries Hiring

  • Healthcare & Medical Services

What South Carolina Employers Look For

The qualifications that appear most often in licensed practical nurse jobs across South Carolina.

  • Active Licensed Practical Nurse license issued or recognized by the South Carolina Board of Nursing
  • Graduate of a state-approved practical nursing program with NCLEX-PN passage
  • Minimum one year of clinical experience in a long-term care or acute care setting
  • Current BLS or CPR certification from an accredited provider
  • Proficiency in electronic health records documentation and medication administration
  • Strong communication skills and ability to work rotating or weekend shifts

Licensed Practical Nurse Jobs in South Carolina: Frequently Asked Questions

How do you become a licensed practical nurse in South Carolina?

You become a licensed practical nurse in South Carolina by completing a state-approved practical nursing program, passing the NCLEX-PN exam, and applying for licensure through the South Carolina Board of Nursing. Programs are available at technical colleges throughout the state, including Midlands Technical College and Greenville Technical College. Once licensed, you may also apply through endorsement if you hold an active LPN license from another state.

How much do licensed practical nurses make in South Carolina?

Licensed practical nurses in South Carolina earn a median of about $61,820 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $50,370 for the lowest 10% to over $76,420 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire licensed practical nurses in South Carolina?

Employers hiring licensed practical nurses in South Carolina right now include BAYADA Home Health Care, PruittHealth, and Angels of Care Pediatric Home Health, based on current listings on Migrate Mate as of August 2026. Large health systems like Prisma Health and MUSC Health, along with long-term care networks and correctional health contractors, consistently post LPN openings across South Carolina's major metros and rural counties.

Which South Carolina cities have the most licensed practical nurse jobs?

Greer, Columbia, and Mount Pleasant have the most licensed practical nurse openings in South Carolina. Columbia leads as the state capital and home to major systems like Prisma Health, while Charleston's medical district anchors demand in the Lowcountry and Greenville's growing hospital network drives consistent hiring in the Upstate region.

Are there remote licensed practical nurse jobs in South Carolina?

Yes, but they're rare. About 0% of licensed practical nurse openings tied to South Carolina are remote or hybrid as of August 2026, reflecting the hands-on, bedside nature of most LPN work. The narrow exceptions include telephone triage roles and care coordination positions that some larger South Carolina health systems have moved to a hybrid model.

How can I get hired as a licensed practical nurse in South Carolina with little or no experience?

The most realistic entry path is applying directly to long-term care facilities and skilled nursing facilities, which tend to hire new LPN graduates before hospital systems do. Employers like PruittHealth and Agape Care, which operate across South Carolina, regularly onboard new graduates. Completing a clinical rotation at a South Carolina technical college and holding current NCLEX-PN licensure through the South Carolina Board of Nursing gives candidates the strongest edge. Certified nursing assistant experience is a common and recognized stepping stone.

Where can I find and apply to licensed practical nurse jobs in South Carolina?

You can find and apply to licensed practical nurse jobs in South Carolina on Migrate Mate, which lists current openings from employers across the state. Search the listings to find roles that match your experience level, preferred location, and setting, then apply directly to the ones that fit.

See All 94 Licensed Practical Nurse Jobs in South Carolina

Find roles in South Carolina that match your experience and apply in just a few clicks.

Find Licensed Practical Nurse Jobs