Licensed Practical Nurse Jobs in South Carolina
Licensed Practical Nurse jobs in South Carolina concentrate in long-term care, hospital systems, and correctional health, with steady demand from entry-level to charge supervision across the state. Columbia, Greenville, and Charleston lead hiring activity, anchored by employers like Prisma Health, MUSC Health, and Grand Strand Medical Center. The highest-demand specialties are geriatric care, med-surg, and behavioral health. See the openings below and apply to the ones that match your experience.
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Showing 5 of 77+ Licensed Practical Nurse jobs
- $32.05-$40.06
- Choice of PPO or HSA medical plans with free telehealth.
- Paid time off.
- Up to $1,000 in free healthcare services with Amedisys HSA plan.
- Up to $500 in wellness rewards for activities-use for spa, gym, sports, hobbies, pets and more.*
- Mental health support with up to five free counseling sessions through the Employee Assistance program.
- 401(k) with a company match.
- Family support with infertility treatment coverage*, adoption reimbursement, paid parental and family caregiver leave.
- Fleet vehicle program (restrictions apply) and mileage reimbursement.
- And more.
- Benefit eligibility can vary by position and shift status.
- Participation requires enrollment in an Amedisys medical plan.
- Verify plan of care with the RN prior to each visit.
- Collaborate with physician and RN frequently to ensure patient needs are being met; Notify them as soon as possible when patient condition changes.
- Teach patients and caregivers self-care techniques.
- Check vital signs.
- Review all medications and perform a medication reconciliation at each visit.
- Perform specialized procedures ordered by physician (i.e. foley catheter change).
- Prepare equipment and materials for treatments using the aseptic technique.
- Complete documentation timely and accurately.
- One year of clinical LPN experience.
- Current LPN license, specific to the state(s) you are assigned to work.
- Current CPR certification.
- Valid driver's license, reliable transportation and liability insurance.
Amedisys is an equal opportunity employer. All qualified employees and applicants will receive consideration for employment without regard to race, color, religion, sex, age, pregnancy, marital status, national origin, citizenship status, disability, military status, sexual orientation, genetic predisposition or carrier status or any other legally protected characteristic.
- $32.05-$40.06
- Choice of PPO or HSA medical plans with free telehealth.
- Paid time off.
- Up to $1,000 in free healthcare services with Amedisys HSA plan.
- Up to $500 in wellness rewards for activities-use for spa, gym, sports, hobbies, pets and more.*
- Mental health support with up to five free counseling sessions through the Employee Assistance program.
- 401(k) with a company match.
- Family support with infertility treatment coverage*, adoption reimbursement, paid parental and family caregiver leave.
- Fleet vehicle program (restrictions apply) and mileage reimbursement.
- And more.
- Benefit eligibility can vary by position and shift status.
- Participation requires enrollment in an Amedisys medical plan.
- Verify plan of care with the RN prior to each visit.
- Collaborate with physician and RN frequently to ensure patient needs are being met; Notify them as soon as possible when patient condition changes.
- Teach patients and caregivers self-care techniques.
- Check vital signs.
- Review all medications and perform a medication reconciliation at each visit.
- Perform specialized procedures ordered by physician (i.e. foley catheter change).
- Prepare equipment and materials for treatments using the aseptic technique.
- Complete documentation timely and accurately.
- One year of clinical LPN experience.
- Current LPN license, specific to the state(s) you are assigned to work.
- Current CPR certification.
- Valid driver's license, reliable transportation and liability insurance.
Amedisys is an equal opportunity employer. All qualified employees and applicants will receive consideration for employment without regard to race, color, religion, sex, age, pregnancy, marital status, national origin, citizenship status, disability, military status, sexual orientation, genetic predisposition or carrier status or any other legally protected characteristic.
See All 77 Licensed Practical Nurse Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find Licensed Practical Nurse JobsLicensed Practical Nurse Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Licensed Practical Nurse Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring
Top Industries Hiring
- Insurance
- Healthcare & Medical Services
What South Carolina Employers Look For
The qualifications that appear most often in licensed practical nurse jobs across South Carolina.
- Active Licensed Practical Nurse license issued or recognized by the South Carolina Board of Nursing
- Graduate of a state-approved practical nursing program with NCLEX-PN passage
- Minimum one year of clinical experience in a long-term care or acute care setting
- Current BLS or CPR certification from an accredited provider
- Proficiency in electronic health records documentation and medication administration
- Strong communication skills and ability to work rotating or weekend shifts
Licensed Practical Nurse Jobs in South Carolina: Frequently Asked Questions
How do you become a licensed practical nurse in South Carolina?
You become a licensed practical nurse in South Carolina by completing a state-approved practical nursing program, passing the NCLEX-PN exam, and applying for licensure through the South Carolina Board of Nursing. Programs are available at technical colleges throughout the state, including Midlands Technical College and Greenville Technical College. Once licensed, you may also apply through endorsement if you hold an active LPN license from another state.
How much do licensed practical nurses make in South Carolina?
Licensed practical nurses in South Carolina earn a median of about $61,820 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $50,370 for the lowest 10% to over $76,420 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire licensed practical nurses in South Carolina?
Employers hiring licensed practical nurses in South Carolina right now include BAYADA Home Health Care, OneWell Health Care, and Your Health Organization, based on current listings on Migrate Mate as of October 2026. Large health systems like Prisma Health and MUSC Health, along with long-term care networks and correctional health contractors, consistently post LPN openings across South Carolina's major metros and rural counties.
Which South Carolina cities have the most licensed practical nurse jobs?
Columbia, Greer, and Charleston have the most licensed practical nurse openings in South Carolina. Columbia leads as the state capital and home to major systems like Prisma Health, while Charleston's medical district anchors demand in the Lowcountry and Greenville's growing hospital network drives consistent hiring in the Upstate region.
Are there remote licensed practical nurse jobs in South Carolina?
Yes, but they're rare. About 0% of licensed practical nurse openings tied to South Carolina are remote or hybrid as of October 2026, reflecting the hands-on, bedside nature of most LPN work. The narrow exceptions include telephone triage roles and care coordination positions that some larger South Carolina health systems have moved to a hybrid model.
How can I get hired as a licensed practical nurse in South Carolina with little or no experience?
The most realistic entry path is applying directly to long-term care facilities and skilled nursing facilities, which tend to hire new LPN graduates before hospital systems do. Employers like PruittHealth and Agape Care, which operate across South Carolina, regularly onboard new graduates. Completing a clinical rotation at a South Carolina technical college and holding current NCLEX-PN licensure through the South Carolina Board of Nursing gives candidates the strongest edge. Certified nursing assistant experience is a common and recognized stepping stone.
Where can I find and apply to licensed practical nurse jobs in South Carolina?
You can find and apply to licensed practical nurse jobs in South Carolina on Migrate Mate, which lists current openings from employers across the state. Search the listings to find roles that match your experience level, preferred location, and setting, then apply directly to the ones that fit.
See All 77 Licensed Practical Nurse Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find Licensed Practical Nurse Jobs