RN Home Health Jobs in South Carolina

RN Home Health jobs in South Carolina are concentrated in Columbia, Charleston, and Greenville, where growing senior populations and hospital-at-home programs have pushed demand for skilled home health nurses to some of the highest levels in the Southeast. Major employers with a lasting presence across the state include Amedisys, LHC Group, and Prisma Health Home Health. The most in-demand specialties are wound care, cardiac monitoring, and post-acute recovery nursing, with openings at every level from newly licensed nurses to experienced case managers. See the openings below and apply to the ones that match your experience.

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Overview

Open roles88
Top employerAmedisys
Top cityColumbia, SC
Cities hiring44
Work type100% On-site
Top industryHealthcare

Showing 5 of 88+ RN Home Health jobs

Spartanburg Regional Healthcare System
Registered Nurse (RN) - Home Health
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Spartanburg Regional Healthcare System
Added 1d ago
Registered Nurse (RN) - Home Health
Spartanburg Regional Healthcare System
Spartanburg, South Carolina
Healthcare Administration
Patient Services & Wellbeing
Social Work & Counseling
CPR Certification

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Angels of Care Pediatric Home Health
Licensed Practical Nurse (LPN) / Registered Nurse (RN) – Pediatric Home Health
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Angels of Care Pediatric Home Health
Added 1d ago
Licensed Practical Nurse (LPN) / Registered Nurse (RN) – Pediatric Home Health
Angels of Care Pediatric Home Health
Summerville, South Carolina
Healthcare Administration
Nursing
Patient Services & Wellbeing
1,001-5,000

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PruittHealth
Registered Nurse RN Home Health
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PruittHealth
Added 1d ago
Registered Nurse RN Home Health
PruittHealth
Rock Hill, South Carolina
Program Management
Project Management
Quality Assurance & Testing (QA Testing)
CPR Certification
10,000+

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Spartanburg Regional Healthcare System
Weekend Staffing Team-RN Level II-Home Health
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Spartanburg Regional Healthcare System
Added 1d ago
Weekend Staffing Team-RN Level II-Home Health
Spartanburg Regional Healthcare System
Spartanburg, South Carolina
Healthcare Administration
Nursing
Patient Services & Wellbeing
CPR Certification

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Advocate Aurora Health
Registered Nurse - Home Health York FT Weekend Days
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Advocate Aurora Health
Added 2d ago
Registered Nurse - Home Health York FT Weekend Days
Advocate Aurora Health
Rock Hill, South Carolina
Healthcare Administration
Nursing
Patient Services & Wellbeing
$35.5 - $53.25/hr
BLS Certification
10,000+

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RN Home Health Jobs by City in South Carolina

Where South Carolina roles are concentrated, by current openings.

Columbia
8 jobs
Rock Hill
7 jobs
Aiken
5 jobs
Ladson
4 jobs
Bluffton
4 jobs
Florence
4 jobs
Greenville
4 jobs
Spartanburg
4 jobs
Myrtle Beach
4 jobs

RN Home Health Job Market in South Carolina

A snapshot from current South Carolina openings, updated as new roles post.

Who's Hiring

  • Amedisys
    Amedisys12
  • CenterWell
    CenterWell11
  • Professional Case Management
    Professional Case Management10
  • PruittHealth
    PruittHealth9
  • Enhabit Home Health & Hospice
    Enhabit Home Health & Hospice7

Top Industries Hiring

  • Healthcare & Medical Services

What South Carolina Employers Look For

The qualifications that appear most often in RN home health jobs across South Carolina.

  • Active registered nurse license issued or recognized by the South Carolina Board of Nursing
  • Current BLS certification required by most South Carolina home health employers
  • Minimum one year of clinical nursing experience, preferably in medical-surgical or acute care
  • Valid driver's license and reliable transportation for patient home visits across South Carolina
  • Proficiency with electronic health records systems used in South Carolina home health settings
  • Strong assessment and autonomous decision-making skills for independent home care environments

RN Home Health Jobs in South Carolina: Frequently Asked Questions

How do you become a rn home health in South Carolina?

To become an rn home health in South Carolina, you must hold an active registered nurse license issued by the South Carolina Board of Nursing, which requires completing an accredited nursing program and passing the NCLEX-RN exam. Most home health employers in South Carolina also expect at least one year of clinical experience, often in a hospital or acute care setting, before transitioning into independent home-based practice.

How much do RN home healths make in South Carolina?

RN home healths in South Carolina earn a median of about $82,360 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $66,860 for the lowest 10% to over $106,520 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire rn home healths in South Carolina?

Companies currently hiring rn home healths in South Carolina include Amedisys, CenterWell, and Professional Case Management, per current listings on Migrate Mate as of August 2026. South Carolina's mix of large regional health systems and national home health agencies means openings are spread across urban centers like Columbia and Charleston as well as smaller communities throughout the state.

Which South Carolina cities have the most rn home health jobs?

Columbia, Rock Hill, and Aiken have the most rn home health openings in South Carolina. Columbia leads because it is the state capital and home to Prisma Health and other large health systems, while Charleston and Greenville drive demand through their growing medical districts, aging residential populations, and the expansion of hospital-at-home services anchored by major regional employers in those metros.

Are there remote rn home health jobs in South Carolina?

Yes, but they're rare. Rn home health work is primarily hands-on and requires in-person patient visits, so most openings are field-based rather than remote. About 0% of rn home health openings tied to South Carolina are remote or hybrid as of August 2026, and those positions tend to be care coordination, telephonic case management, or clinical documentation roles rather than direct patient care.

How can I get hired as a rn home health in South Carolina with little or no experience?

The most realistic entry path is completing a new-graduate residency or transition-to-practice program at a large South Carolina health system such as Prisma Health or MUSC, which builds the acute care foundation most home health employers require before hiring independently. From there, moving into a home health aide, LPN, or hospital med-surg role first, then applying to home health positions after gaining clinical hours, significantly improves your candidacy. Holding a current BLS certification and South Carolina Board of Nursing licensure from day one gives newer applicants a clear edge.

Where can I find and apply to rn home health jobs in South Carolina?

You can find and apply to rn home health jobs in South Carolina on Migrate Mate, which lists current openings from employers hiring across the state. Search the listings to find roles that match your experience, specialty, and preferred location in South Carolina, then apply directly to the ones that fit.

See All 88 RN Home Health Jobs in South Carolina

Find roles in South Carolina that match your experience and apply in just a few clicks.

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