RN Home Health Jobs in South Carolina
RN Home Health jobs in South Carolina are concentrated in Columbia, Charleston, and Greenville, where growing senior populations and hospital-at-home programs have pushed demand for skilled home health nurses to some of the highest levels in the Southeast. Major employers with a lasting presence across the state include Amedisys, LHC Group, and Prisma Health Home Health. The most in-demand specialties are wound care, cardiac monitoring, and post-acute recovery nursing, with openings at every level from newly licensed nurses to experienced case managers. See the openings below and apply to the ones that match your experience.
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Explore opportunities with Amedisys, part of the Optum family of businesses. We provide home health, hospice and community-based services that help people receive quality care where they feel most comfortable: at home. Rooted in personalized care, we support patients and provide comfort through each stage of their health journey, while building trusted relationships along the way. Find a home for your career here. Join us and embrace a culture of Caring. Connecting. Growing together.
As the Executive Director of Operations you will be responsible for the overall operational, financial, and clinical performance of assigned care center(s). This role provides strategic direction and leadership to ensure compliance with all applicable regulations, achievement of key performance metrics, and execution of business development initiatives.
Primary Responsibilities:
- Ensures care center is compliant with all regulations, laws, policies, and procedures
- Educates all staff members about state, federal, and accreditation requirements (as applicable)
- Ensures that all services are billed as provided to the proper payor source
- Directs weekly business development and management team meetings with all appropriate staff and other members of the medical community to promote home care services
- Provides input, guidance, and feedback related to marketing activities and agency marketing plans to ensure that goals for growth are met
- Assigns and directs staff with appropriate skills to perform duties
- Coaches, directs, and encourages staff through formal and informal means
- Analyzes work processes and makes suggestions for improvement
- Responsible for care center financial and clinical performance and delivery of key metrics within the established budget
- Responsible for employment decisions for direct report staff, including decisions to hire, fire, advance, promote, or change status
- Monitors and evaluates employee performance
- Performs other related duties as assigned
You'll be rewarded and recognized for your performance in an environment that will challenge you and give you clear direction on what it takes to succeed in your role as well as provide development for other roles you may be interested in.
Required Qualifications:
- Bachelor's degree in business or a clinical-related field
- 3+ years of leadership or management experience in healthcare, home health, or hospice OR 5+ years of leadership or management experience in healthcare, home health, or hospice in lieu of a degree
Preferred Qualifications:
- Master's degree in business or a clinical-related field
- Current, unencumbered license to practice as a Registered Nurse or other healthcare professional in the assigned state
- Current home health experience
State Specific Requirements:
SC:
- The home health agency shall designate a qualified individual to serve as Administrator/ Director. The Administrator/ Director shall have the authority and responsibility for the functions and activities of the agency and must be available within a reasonable time and distance. A qualified staff member shall be designated in writing to act in the absence of the Administrator/ Director. The home health agency shall designate a physician or a registered nurse to supervise the professional activities in providing home health services. The Administrator/ Director and the Director of Professional Services may be the same individual
Pay is based on several factors including but not limited to local labor markets, education, work experience, certifications, etc. In addition to your salary, we offer benefits such as, a comprehensive benefits package, incentive and recognition programs, equity stock purchase and 401k contribution (all benefits are subject to eligibility requirements). No matter where or when you begin a career with us, you'll find a far-reaching choice of benefits and incentives. The salary for this role will range from $90,000 to $135,000 annually based on full-time employment. We comply with all minimum wage laws as applicable.
At UnitedHealth Group, our mission is to help people live healthier lives and help make the health system work better for everyone. Together, we are shaping the future of healthcare by harnessing technology and innovation to make care simpler to navigate, more affordable and more connected for the people we serve. We are committed to creating an inclusive workplace where everyone feels welcomed, valued, heard and respected, empowering people to bring their authentic selves to work and strengthening our collective impact through diverse talents, backgrounds, experiences and perspectives.
UnitedHealth Group and its affiliated brands are an Equal Employment Opportunity employer under applicable law and qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, sexual orientation, gender identity, disability, or protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations.
UnitedHealth Group and its affiliated brands are a drug-free workplace. Candidates are required to pass a drug test before beginning employment.
See All 88 RN Home Health Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find RN Home Health JobsRN Home Health Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
RN Home Health Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring
- CenterWell14

- Professional Case Management13

- Amedisys11

- Medical Services of America10

- Optum6

Top Industries Hiring
- Healthcare & Medical Services
What South Carolina Employers Look For
The qualifications that appear most often in RN home health jobs across South Carolina.
- Active registered nurse license issued or recognized by the South Carolina Board of Nursing
- Current BLS certification required by most South Carolina home health employers
- Minimum one year of clinical nursing experience, preferably in medical-surgical or acute care
- Valid driver's license and reliable transportation for patient home visits across South Carolina
- Proficiency with electronic health records systems used in South Carolina home health settings
- Strong assessment and autonomous decision-making skills for independent home care environments
RN Home Health Jobs in South Carolina: Frequently Asked Questions
How do you become a rn home health in South Carolina?
To become an rn home health in South Carolina, you must hold an active registered nurse license issued by the South Carolina Board of Nursing, which requires completing an accredited nursing program and passing the NCLEX-RN exam. Most home health employers in South Carolina also expect at least one year of clinical experience, often in a hospital or acute care setting, before transitioning into independent home-based practice.
How much do RN home healths make in South Carolina?
RN home healths in South Carolina earn a median of about $82,360 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $66,860 for the lowest 10% to over $106,520 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire rn home healths in South Carolina?
Companies currently hiring rn home healths in South Carolina include CenterWell, Professional Case Management, and Amedisys, per current listings on Migrate Mate as of October 2026. South Carolina's mix of large regional health systems and national home health agencies means openings are spread across urban centers like Columbia and Charleston as well as smaller communities throughout the state.
Which South Carolina cities have the most rn home health jobs?
Columbia, Rock Hill, and Aiken have the most rn home health openings in South Carolina. Columbia leads because it is the state capital and home to Prisma Health and other large health systems, while Charleston and Greenville drive demand through their growing medical districts, aging residential populations, and the expansion of hospital-at-home services anchored by major regional employers in those metros.
Are there remote rn home health jobs in South Carolina?
Yes, but they're rare. Rn home health work is primarily hands-on and requires in-person patient visits, so most openings are field-based rather than remote. About 0% of rn home health openings tied to South Carolina are remote or hybrid as of October 2026, and those positions tend to be care coordination, telephonic case management, or clinical documentation roles rather than direct patient care.
How can I get hired as a rn home health in South Carolina with little or no experience?
The most realistic entry path is completing a new-graduate residency or transition-to-practice program at a large South Carolina health system such as Prisma Health or MUSC, which builds the acute care foundation most home health employers require before hiring independently. From there, moving into a home health aide, LPN, or hospital med-surg role first, then applying to home health positions after gaining clinical hours, significantly improves your candidacy. Holding a current BLS certification and South Carolina Board of Nursing licensure from day one gives newer applicants a clear edge.
Where can I find and apply to rn home health jobs in South Carolina?
You can find and apply to rn home health jobs in South Carolina on Migrate Mate, which lists current openings from employers hiring across the state. Search the listings to find roles that match your experience, specialty, and preferred location in South Carolina, then apply directly to the ones that fit.
See All 88 RN Home Health Jobs in South Carolina
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