RN Home Health Jobs in South Carolina
RN Home Health jobs in South Carolina are concentrated in Columbia, Charleston, and Greenville, where growing senior populations and hospital-at-home programs have pushed demand for skilled home health nurses to some of the highest levels in the Southeast. Major employers with a lasting presence across the state include Amedisys, LHC Group, and Prisma Health Home Health. The most in-demand specialties are wound care, cardiac monitoring, and post-acute recovery nursing, with openings at every level from newly licensed nurses to experienced case managers. See the openings below and apply to the ones that match your experience.
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SIGN ON BONUS $10,000.00 Eligible Experienced RN
We are hiring a Registered Nurse to join our Home Health team!
- Full-Time; 8:30 am- 5:00 pm
We are proud of our skilled, caring, trustworthy and compassionate Home Health experts. Our clinicians visit patient homes to deliver customized, physician-prescribed care after a hospital stay, illness or injury to rehabilitate and achieve optimal level of independence. Home Health is an alternative to repeated hospitalizations or an extended hospital stay. Nurses and medical professionals work closely with primary care physicians and ensure patients are receiving optimum care tailored to individual needs.
Our Registered Nurses enjoy autonomy while caring for patients in their home environment. The team works with a wide variety of cases such as: Wound Care, Cardiac, Diabetes, Endocrine, Musculosketal, Pressure Ulcers, Infusion, etc. The average length of patient care is 47 days.
The Registered Nurse provides skilled nursing services within the home care setting in accordance with the orders of a physician and under a plan of care. Through use of the nursing process, utilizes knowledge and skills at a competent level to provide direct age-specific and culturally appropriate patient care management in the homecare setting. The RN also serves as a clinical resource, participates in patient and staff education, demonstrates the use of independent nursing judgment, and serves as a preceptor. Develops and coordinates the plan of care and provides case management. Performs other duties as assigned.
Minimum Requirements
Education
- Graduate of an approved nursing program
Experience
- One (1) year of recent clinical nursing experience
License/Registration/Certifications
- Current license to practice as a Registered Nurse in South Carolina
- Valid SC driver's license with good driving record
- CPR certification
Core Job Responsibilities
- Responsible for continuous review of all aspects of patients on his/her caseload to include but not limited to: appropriate utilization of services; review of documentation in the medical record; maintenance of interdisciplinary communication and discharge planning.
- Completes an initial assessment of patient and family to determine home care needs. Provides a complete physical assessment and history of current and previous illness(es) and medication reconciliation.
- Collaborates with patients, families, and other members of the interdisciplinary care team to establish appropriate treatment plan and develop a plan of care.
- Initiates the plan of care, makes necessary revisions as patient status, and needs change. Regularly re-evaluates patient nursing needs.
- Initiates and facilitates interdisciplinary collaboration to enhance outcomes.
- Initiates appropriate nursing interventions. Provides treatments as prescribed by the physician.
- Provides health care instructions to the patient as appropriate per assessment and plan. Educates the patient and family/caregiver on self-care techniques medications, diet and other instructions as ordered.
- Recognizes and utilizes opportunities for health counseling with patients and families/ caregivers.
- Communicates with the physician regarding the patient's needs and reports changes in the patient's condition; communicates regularly with the interdisciplinary team; communicates with community health related persons to coordinate the plan of care; and communicates on a regular basis with manager.
- Provides supervision of home health aides per regulatory requirements.
- Complies with established policies and procedures.
- Knowledge of and compliance with state, federal, and local regulations for the delivery of home care services.
- Performs other duties as assigned.
See All 88 RN Home Health Jobs in South Carolina
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Find RN Home Health JobsRN Home Health Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
RN Home Health Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring
- Amedisys12

- CenterWell11

- Professional Case Management10

- PruittHealth9

- Enhabit Home Health & Hospice7

Top Industries Hiring
- Healthcare & Medical Services
What South Carolina Employers Look For
The qualifications that appear most often in RN home health jobs across South Carolina.
- Active registered nurse license issued or recognized by the South Carolina Board of Nursing
- Current BLS certification required by most South Carolina home health employers
- Minimum one year of clinical nursing experience, preferably in medical-surgical or acute care
- Valid driver's license and reliable transportation for patient home visits across South Carolina
- Proficiency with electronic health records systems used in South Carolina home health settings
- Strong assessment and autonomous decision-making skills for independent home care environments
RN Home Health Jobs in South Carolina: Frequently Asked Questions
How do you become a rn home health in South Carolina?
To become an rn home health in South Carolina, you must hold an active registered nurse license issued by the South Carolina Board of Nursing, which requires completing an accredited nursing program and passing the NCLEX-RN exam. Most home health employers in South Carolina also expect at least one year of clinical experience, often in a hospital or acute care setting, before transitioning into independent home-based practice.
How much do RN home healths make in South Carolina?
RN home healths in South Carolina earn a median of about $82,360 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $66,860 for the lowest 10% to over $106,520 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire rn home healths in South Carolina?
Companies currently hiring rn home healths in South Carolina include Amedisys, CenterWell, and Professional Case Management, per current listings on Migrate Mate as of August 2026. South Carolina's mix of large regional health systems and national home health agencies means openings are spread across urban centers like Columbia and Charleston as well as smaller communities throughout the state.
Which South Carolina cities have the most rn home health jobs?
Columbia, Rock Hill, and Aiken have the most rn home health openings in South Carolina. Columbia leads because it is the state capital and home to Prisma Health and other large health systems, while Charleston and Greenville drive demand through their growing medical districts, aging residential populations, and the expansion of hospital-at-home services anchored by major regional employers in those metros.
Are there remote rn home health jobs in South Carolina?
Yes, but they're rare. Rn home health work is primarily hands-on and requires in-person patient visits, so most openings are field-based rather than remote. About 0% of rn home health openings tied to South Carolina are remote or hybrid as of August 2026, and those positions tend to be care coordination, telephonic case management, or clinical documentation roles rather than direct patient care.
How can I get hired as a rn home health in South Carolina with little or no experience?
The most realistic entry path is completing a new-graduate residency or transition-to-practice program at a large South Carolina health system such as Prisma Health or MUSC, which builds the acute care foundation most home health employers require before hiring independently. From there, moving into a home health aide, LPN, or hospital med-surg role first, then applying to home health positions after gaining clinical hours, significantly improves your candidacy. Holding a current BLS certification and South Carolina Board of Nursing licensure from day one gives newer applicants a clear edge.
Where can I find and apply to rn home health jobs in South Carolina?
You can find and apply to rn home health jobs in South Carolina on Migrate Mate, which lists current openings from employers hiring across the state. Search the listings to find roles that match your experience, specialty, and preferred location in South Carolina, then apply directly to the ones that fit.
See All 88 RN Home Health Jobs in South Carolina
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