Registered Respiratory Therapist Jobs in South Carolina

Registered Respiratory Therapist jobs in South Carolina draw steady demand across hospital systems, long-term acute care, and cardiopulmonary rehabilitation units, with openings at entry, mid-career, and senior levels throughout the year. Columbia, Greenville, and Charleston are the primary hiring markets, home to major systems like Prisma Health, Bon Secours St. Francis, and MUSC Health. Critical care, neonatal and pediatric respiratory therapy, and pulmonary function testing are the most consistently requested specializations statewide. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles67
Top employerPrisma Health
Top cityGreenville, SC
Cities hiring25
Work type100% On-site
Top industryHealthcare

Showing 5 of 67+ Registered Respiratory Therapist jobs

Tenet Healthcare
Lead Respiratory Therapist
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Tenet Healthcare
New 18h ago
Lead Respiratory Therapist
Tenet Healthcare
Rock Hill, South Carolina
Healthcare Administration
Patient Services & Wellbeing
Public Health
NRP Certification
10,000+

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Spartanburg Regional Healthcare System
Respiratory Therapist (RRT) NICU
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Spartanburg Regional Healthcare System
Added 1d ago
Respiratory Therapist (RRT) NICU
Spartanburg Regional Healthcare System
Spartanburg, South Carolina
Healthcare Administration
Patient Services & Wellbeing
Social Work & Counseling
NRP Certification

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Prisma Health
Respiratory Therapist PT Variable NICU
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Prisma Health
Added 2d ago
Respiratory Therapist PT Variable NICU
Prisma Health
Greenville, South Carolina
Healthcare Administration
Human Resources
Patient Services & Wellbeing
NRP Certification
10,000+

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Prisma Health
Respiratory Therapist FT Nights NICU
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Prisma Health
Added 2d ago
Respiratory Therapist FT Nights NICU
Prisma Health
Greenville, South Carolina
Healthcare Administration
Human Resources
Patient Services & Wellbeing
NRP Certification
10,000+

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V
Travel Respiratory Therapist
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V
Added 2d ago
Travel Respiratory Therapist
Voyage Health
Columbia, South Carolina
Healthcare Administration
Mental & Behavioral Health
Social Work & Counseling
$1,789 - $1,883/yr

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See All 67 Registered Respiratory Therapist Jobs in South Carolina

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Registered Respiratory Therapist Jobs by City in South Carolina

Where South Carolina roles are concentrated, by current openings.

Greenville
9 jobs
Columbia
6 jobs
Florence
6 jobs
Charleston
6 jobs
Spartanburg
6 jobs
Walterboro
4 jobs
Greer
3 jobs
Myrtle Beach
3 jobs
Aiken
2 jobs

Registered Respiratory Therapist Job Market in South Carolina

A snapshot from current South Carolina openings, updated as new roles post.

Who's Hiring

  • Prisma Health
    Prisma Health13
  • V
    Voyage Health12
  • Spartanburg Regional Healthcare System
    Spartanburg Regional Healthcare System9
  • McLeod Health
    McLeod Health5
  • American Traveler
    American Traveler3

Top Industries Hiring

  • Healthcare & Medical Services

What South Carolina Employers Look For

The qualifications that appear most often in registered respiratory therapist jobs across South Carolina.

  • Active South Carolina respiratory care practitioner license issued by the South Carolina Board of Medical Examiners
  • Registered Respiratory Therapist credential from the National Board for Respiratory Care
  • Completion of a COARC-accredited associate or bachelor's degree program in respiratory therapy
  • BLS certification required at time of hire, ACLS preferred for critical care settings
  • Minimum one to two years of clinical experience in an acute care or ICU environment
  • Proficiency with mechanical ventilation, arterial blood gas analysis, and airway management

Registered Respiratory Therapist Jobs in South Carolina: Frequently Asked Questions

How do you become a registered respiratory therapist in South Carolina?

You must hold an active respiratory care practitioner license issued by the South Carolina Board of Medical Examiners before practicing in the state. To qualify, complete a COARC-accredited respiratory therapy program at an associate or bachelor's level, then pass the National Board for Respiratory Care examinations to earn the Registered Respiratory Therapist credential. South Carolina requires this state licensure in addition to the national credential, and renewal follows a biennial cycle.

How much do registered respiratory therapists make in South Carolina?

Registered respiratory therapists in South Carolina earn a median of about $77,740 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $63,700 for the lowest 10% to over $90,670 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire registered respiratory therapists in South Carolina?

South Carolina registered respiratory therapist roles are posted by Prisma Health, Voyage Health, and Spartanburg Regional Healthcare System and others right now, based on current listings on Migrate Mate as of August 2026. Large integrated health systems anchored in Columbia, Greenville, and Charleston drive the majority of consistent openings across the state.

Which South Carolina cities have the most registered respiratory therapist jobs?

Greenville, Columbia, and Florence consistently post the highest concentration of registered respiratory therapist openings in South Carolina. Columbia's density is driven by Prisma Health's flagship hospitals and the presence of the Medical University of South Carolina in Charleston, while Greenville benefits from Bon Secours St. Francis and a growing network of regional medical centers serving the Upstate.

Are there remote registered respiratory therapist jobs in South Carolina?

Yes, but they're rare. Registered respiratory therapy is a hands-on clinical role requiring direct patient contact, so remote work is limited by nature. About 0% of registered respiratory therapist openings tied to South Carolina are remote or hybrid as of August 2026, and those positions are largely in clinical education, telehealth case management, or utilization review rather than direct bedside care.

How can I get hired as a registered respiratory therapist in South Carolina with little or no experience?

The most realistic entry path is applying directly to new-graduate respiratory therapy positions at large South Carolina health systems like Prisma Health or MUSC Health, both of which offer structured onboarding programs for new RRT credential holders. Internships completed during an accredited program at institutions like Trident Technical College or Greenville Technical College often convert into offers. Holding an active South Carolina respiratory care practitioner license and a current BLS certification before applying gives candidates a clear advantage over unlicensed applicants.

Where can I find and apply to registered respiratory therapist jobs in South Carolina?

You can find and apply to registered respiratory therapist jobs in South Carolina on Migrate Mate, which lists current South Carolina openings in one place. Search the listings, find the roles that match your experience and preferred location, and apply directly to the ones that fit.

See All 67 Registered Respiratory Therapist Jobs in South Carolina

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