Registered Respiratory Therapist Jobs in South Carolina
Registered Respiratory Therapist jobs in South Carolina draw steady demand across hospital systems, long-term acute care, and cardiopulmonary rehabilitation units, with openings at entry, mid-career, and senior levels throughout the year. Columbia, Greenville, and Charleston are the primary hiring markets, home to major systems like Prisma Health, Bon Secours St. Francis, and MUSC Health. Critical care, neonatal and pediatric respiratory therapy, and pulmonary function testing are the most consistently requested specializations statewide. Scan the live roles below and apply to whichever ones fit.
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At Rotech Healthcare Inc., we’re more than a medical equipment provider—we’re a trusted partner in patient care. As a national leader in ventilators, oxygen therapy, sleep apnea treatment, wound care, diabetic solutions, and other home medical equipment, we empower patients to manage their health from the comfort of home.
With hundreds of locations across 45 states, our team delivers high-quality products, exceptional service, and compassionate support that helps patients live more comfortably, independently, and actively. Whether you're a clinician, technician, or healthcare administrator, your work at Rotech directly improves lives.
Explore more about our mission and services at Rotech.com.
Respiratory Therapist or RN – Home Healthcare
Deliver Care Where It Matters Most – In the Patient’s Home
Rotech Healthcare Inc. is seeking a compassionate and clinically skilled Respiratory Therapist (RRT) or Registered Nurse (RN) to join our team. If you’re looking for a meaningful role that allows you to build relationships, provide hands-on care, and make a lasting impact in patients’ lives—all outside of a traditional clinical setting—this is the opportunity for you. In this role, you’ll provide in-home respiratory therapy and clinical support to patients using ventilators, oxygen therapy, and other advanced equipment. You’ll be part of a team that values autonomy, patient education, and personalized care.
External candidates are eligible for a $2000 gross sign on bonus to be paid after 60 days and another $2000 after 180 days of continuous employment
Essential Job Duties and Responsibilities
- Maintains a complete listing of all current respiratory patients
- Provides initial and ongoing phone contacts with all respiratory patients per Rotech policy and procedure
- Provides in-home visits to patients per Rotech’s policy and procedure
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Conducts patient assessment per Rotech’s policy and procedure and the physician’s order Patient assessment may include but is not limited to:
- Verbal assessment (e.g., patient history, symptom review, etc.)
- Physical assessment (e.g., lung auscultation, blood pressure, etc.)
- Diagnostics (e.g., spirometry, oximetry, sleep studies)
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Provides patient education as applicable. Education may include but is not limited to:
- Respiratory equipment use and maintenance
- Physician’s prescription for equipment
- Importance of compliance with physician’s prescription
- Benefits of therapy
- Potential consequences of noncompliance
- Potential adverse reactions/side effects from therapy
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Sets up all highly technical respiratory equipment including but not limited to:
- Invasive Ventilator
- Noninvasive Ventilator
- Infant Monitors
- Other high-tech respiratory equipment as defined by scope of service at the branch (e.g., cough assist, negative pressure ventilation, IPPB, etc.)
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Monitors ongoing function of highly technical respiratory equipment including but not limited to:
- Invasive Ventilator
- Noninvasive Ventilator
- Infant Monitors
- Other high-tech respiratory equipment as defined by scope of service at the branch (e.g., cough assist, negative pressure ventilation, IPPB, etc.)
- Maintains documentation of all services provided and all work performed per Rotech’s policies and procedures
- Assumes on-call responsibilities for phone consultations during non-business hours as outlined by Rotech’s policy
- Adjusting ventilator settings according to patient assessment and in alignment with Rotech policy and procedures
- Supports orientation and training of other personnel at the direction of the Area Manager
- Performs other duties as required by state licensure law
- Performs other duties and responsibilities as defined by the Area Manager
Why Join Rotech?
- Deliver care in a flexible, patient-centered environment.
- Be part of a mission-driven team improving lives through home-based therapy.
- Receive comprehensive training and ongoing support.
Employment is contingent on
- Background check (company-wide). Results will not be used automatically to disqualify individuals. Instead, the Company will conduct an individualized assessment that considers the duties of the position, the nature and timing of the offense, and any evidence of rehabilitation, in accordance with applicable laws.
- Drug screen (when applicable for the position)
- Compliance with healthcare facility credentialing process (when applicable for the position)
- Valid driver’s license in state of residence with a clean driving record (when applicable for the position)
- Candidates may qualify through a combination of education, training, and relevant work experience that demonstrates the knowledge, skills, and abilities necessary to successfully perform the essential functions of the position.
- Any education requirements mandated by applicable federal, state, or local law, regulation, licensing requirement, or customer contract.
- Active licensure in your primary state of residence as a Respiratory Therapist (RRT or CRT) or other acceptable medical credential (e.g., RC, RN) based on state licensure laws
- Willingness to obtain licensure in neighboring states if required by service area
Preferred Education and/or Experience
- High school diploma or GED equivalent, preferrred
- Completion of an accredited program in respiratory care, nursing, or a related paramedical field
- Experience in home respiratory care or home healthcare
- Degree in respiratory therapy or a related science
- At least one year of relevant clinical experience
- Familiarity with medical terminology
Skills & Competencies
- Strong attention to detail and ability to multi-task effectively
- Excellent verbal and written communication skills in English
- Ability to interpret and respond to various forms of communication (verbal, written, visual)
- Maintain confidentiality and handle sensitive information with discretion
- Demonstrated problem-solving, time management, and organizational skills
- Capable of working independently and collaboratively within a team
Technical Proficiency
- Proficient in Microsoft Office (Outlook, Word, Excel)
- Comfortable with email communication, internet research, and using office equipment (fax, copier, printer, phone, computer/tablet)
Physical Requirements
- Ability to lift and transport patient equipment (minimum 65 lbs)
- Regular contact with patients and equipment may involve exposure to contagious pathogens
- Must be able to sit, stand, walk, talk, and listen for extended periods
- Requires close vision for reading small print on screens and paperwork
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Must comply with Rotech’s Respiratory Protection & N95 Mask Fit Testing Policy, including:
- Medical evaluation and fit testing
- Annual recertification
- Maintaining a clean-shaven face for proper mask seal per OSHA guidelines
See All 58 Registered Respiratory Therapist Jobs in South Carolina
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Find JobsRegistered Respiratory Therapist Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Registered Respiratory Therapist Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Healthcare & Medical Services
What South Carolina Employers Look For
The qualifications that appear most often in registered respiratory therapist jobs across South Carolina.
- Active South Carolina respiratory care practitioner license issued by the South Carolina Board of Medical Examiners
- Registered Respiratory Therapist credential from the National Board for Respiratory Care
- Completion of a COARC-accredited associate or bachelor's degree program in respiratory therapy
- BLS certification required at time of hire, ACLS preferred for critical care settings
- Minimum one to two years of clinical experience in an acute care or ICU environment
- Proficiency with mechanical ventilation, arterial blood gas analysis, and airway management
Registered Respiratory Therapist Jobs in South Carolina: Frequently Asked Questions
How do you become a registered respiratory therapist in South Carolina?
You must hold an active respiratory care practitioner license issued by the South Carolina Board of Medical Examiners before practicing in the state. To qualify, complete a COARC-accredited respiratory therapy program at an associate or bachelor's level, then pass the National Board for Respiratory Care examinations to earn the Registered Respiratory Therapist credential. South Carolina requires this state licensure in addition to the national credential, and renewal follows a biennial cycle.
How much do registered respiratory therapists make in South Carolina?
Registered respiratory therapists in South Carolina earn a median of about $77,740 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $63,700 for the lowest 10% to over $90,670 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire registered respiratory therapists in South Carolina?
South Carolina registered respiratory therapist roles are posted by Prisma Health, ATC Healthcare, and American Traveler and others right now, based on current listings on Migrate Mate as of October 2026. Large integrated health systems anchored in Columbia, Greenville, and Charleston drive the majority of consistent openings across the state.
Which South Carolina cities have the most registered respiratory therapist jobs?
Columbia, Florence, and Greenville consistently post the highest concentration of registered respiratory therapist openings in South Carolina. Columbia's density is driven by Prisma Health's flagship hospitals and the presence of the Medical University of South Carolina in Charleston, while Greenville benefits from Bon Secours St. Francis and a growing network of regional medical centers serving the Upstate.
Are there remote registered respiratory therapist jobs in South Carolina?
Yes, but they're rare. Registered respiratory therapy is a hands-on clinical role requiring direct patient contact, so remote work is limited by nature. About 33% of registered respiratory therapist openings tied to South Carolina are remote or hybrid as of October 2026, and those positions are largely in clinical education, telehealth case management, or utilization review rather than direct bedside care.
How can I get hired as a registered respiratory therapist in South Carolina with little or no experience?
The most realistic entry path is applying directly to new-graduate respiratory therapy positions at large South Carolina health systems like Prisma Health or MUSC Health, both of which offer structured onboarding programs for new RRT credential holders. Internships completed during an accredited program at institutions like Trident Technical College or Greenville Technical College often convert into offers. Holding an active South Carolina respiratory care practitioner license and a current BLS certification before applying gives candidates a clear advantage over unlicensed applicants.
Where can I find and apply to registered respiratory therapist jobs in South Carolina?
You can find and apply to registered respiratory therapist jobs in South Carolina on Migrate Mate, which lists current South Carolina openings in one place. Search the listings, find the roles that match your experience and preferred location, and apply directly to the ones that fit.
See All 58 Registered Respiratory Therapist Jobs in South Carolina
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