Registered Respiratory Therapist Jobs in South Carolina

Registered Respiratory Therapist jobs in South Carolina draw steady demand across hospital systems, long-term acute care, and cardiopulmonary rehabilitation units, with openings at entry, mid-career, and senior levels throughout the year. Columbia, Greenville, and Charleston are the primary hiring markets, home to major systems like Prisma Health, Bon Secours St. Francis, and MUSC Health. Critical care, neonatal and pediatric respiratory therapy, and pulmonary function testing are the most consistently requested specializations statewide. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles58
Top employerPrisma Health
Top cityColumbia, SC
Cities hiring27
Work type67% On-site
Top industryHealthcare

Showing 5 of 58+ Registered Respiratory Therapist jobs

Respiratory Therapist
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Added 1d ago
Respiratory Therapist
Rotech Healthcare Inc.
Summerville, South Carolina
Clinical Support
Healthcare Administration
Laboratory Science
High school diploma or GED
1,001-5,000

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Respiratory Therapy - Registered Respiratory Therapist
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Added 3d ago
Respiratory Therapy - Registered Respiratory Therapist
Vibra Travels
Columbia, South Carolina
Clinical Support
Healthcare Administration
Mental & Behavioral Health
BLS Certification
51-200

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Respiratory Therapist - Part Time
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Added 5d ago
Respiratory Therapist - Part Time
Ernest Health
Cayce, South Carolina
Healthcare Administration
Patient Services & Wellbeing
Public Health
CPR Certification
1,001-5,000

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Respiratory Therapist
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Added 6d ago
Respiratory Therapist
Broad River Rehab
Myrtle Beach, South Carolina
Account Management
Business Development
Customer Success
Sales
201-500

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Respiratory Therapist / RT / PRN
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Added 6d ago
Respiratory Therapist / RT / PRN
Broad River Rehab
Myrtle Beach, South Carolina
Allied Health
Healthcare Administration
Patient Services & Wellbeing
201-500

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Registered Respiratory Therapist Jobs by City in South Carolina

Where South Carolina roles are concentrated, by current openings.

Columbia
5 jobs
Florence
5 jobs
Greenville
5 jobs
Spartanburg
5 jobs
Charleston
4 jobs
Fort Mill
3 jobs
Myrtle Beach
3 jobs
Aiken
2 jobs
Conway
2 jobs

Registered Respiratory Therapist Job Market in South Carolina

A snapshot from current South Carolina openings, updated as new roles post.

Who's Hiring

Prisma Health9 open roles
ATC Healthcare5 open roles
American Traveler5 open roles

Top Industries Hiring

  • Healthcare & Medical Services

What South Carolina Employers Look For

The qualifications that appear most often in registered respiratory therapist jobs across South Carolina.

  • Active South Carolina respiratory care practitioner license issued by the South Carolina Board of Medical Examiners
  • Registered Respiratory Therapist credential from the National Board for Respiratory Care
  • Completion of a COARC-accredited associate or bachelor's degree program in respiratory therapy
  • BLS certification required at time of hire, ACLS preferred for critical care settings
  • Minimum one to two years of clinical experience in an acute care or ICU environment
  • Proficiency with mechanical ventilation, arterial blood gas analysis, and airway management

Registered Respiratory Therapist Jobs in South Carolina: Frequently Asked Questions

How do you become a registered respiratory therapist in South Carolina?

You must hold an active respiratory care practitioner license issued by the South Carolina Board of Medical Examiners before practicing in the state. To qualify, complete a COARC-accredited respiratory therapy program at an associate or bachelor's level, then pass the National Board for Respiratory Care examinations to earn the Registered Respiratory Therapist credential. South Carolina requires this state licensure in addition to the national credential, and renewal follows a biennial cycle.

How much do registered respiratory therapists make in South Carolina?

Registered respiratory therapists in South Carolina earn a median of about $77,740 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $63,700 for the lowest 10% to over $90,670 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire registered respiratory therapists in South Carolina?

South Carolina registered respiratory therapist roles are posted by Prisma Health, ATC Healthcare, and American Traveler and others right now, based on current listings on Migrate Mate as of October 2026. Large integrated health systems anchored in Columbia, Greenville, and Charleston drive the majority of consistent openings across the state.

Which South Carolina cities have the most registered respiratory therapist jobs?

Columbia, Florence, and Greenville consistently post the highest concentration of registered respiratory therapist openings in South Carolina. Columbia's density is driven by Prisma Health's flagship hospitals and the presence of the Medical University of South Carolina in Charleston, while Greenville benefits from Bon Secours St. Francis and a growing network of regional medical centers serving the Upstate.

Are there remote registered respiratory therapist jobs in South Carolina?

Yes, but they're rare. Registered respiratory therapy is a hands-on clinical role requiring direct patient contact, so remote work is limited by nature. About 33% of registered respiratory therapist openings tied to South Carolina are remote or hybrid as of October 2026, and those positions are largely in clinical education, telehealth case management, or utilization review rather than direct bedside care.

How can I get hired as a registered respiratory therapist in South Carolina with little or no experience?

The most realistic entry path is applying directly to new-graduate respiratory therapy positions at large South Carolina health systems like Prisma Health or MUSC Health, both of which offer structured onboarding programs for new RRT credential holders. Internships completed during an accredited program at institutions like Trident Technical College or Greenville Technical College often convert into offers. Holding an active South Carolina respiratory care practitioner license and a current BLS certification before applying gives candidates a clear advantage over unlicensed applicants.

Where can I find and apply to registered respiratory therapist jobs in South Carolina?

You can find and apply to registered respiratory therapist jobs in South Carolina on Migrate Mate, which lists current South Carolina openings in one place. Search the listings, find the roles that match your experience and preferred location, and apply directly to the ones that fit.

See All 58 Registered Respiratory Therapist Jobs in South Carolina

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