Healthcare Jobs in South Carolina

Healthcare jobs in South Carolina are concentrated in Columbia, Charleston, and Greenville, where large systems like Prisma Health, MUSC Health, and Bon Secours fuel consistent hiring from entry-level roles to senior clinical and administrative positions. Demand is strongest in behavioral health, home health and hospice, and outpatient primary care, reflecting both the state's aging population and continued investment in community-based services. South Carolina's healthcare market has expanded steadily, making it one of the more active hiring environments in the Southeast. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles85
Top employerOptum
Top cityLexington County, SC
Cities hiring28
Work type62% Hybrid
Top industryHealthcare

Showing 5 of 85+ Healthcare jobs

Active Day
Healthcare Talent Acquisition Specialist
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Active Day
Added 1d ago
Healthcare Talent Acquisition Specialist
Active Day
West Columbia, South Carolina
Administrative & Office Support
Human Resources (HR) — Generalist
Recruiting & Talent Acquisition
Hybrid
High school diploma or GED
1,001-5,000

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Optum
Certified Medical Assistant Urgent Care - Colonial Healthcare
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Optum
Added 1d ago
Certified Medical Assistant Urgent Care - Colonial Healthcare
Optum
Sumter, South Carolina
Healthcare Administration
Medical Assistant
Patient Services & Wellbeing
$16 - $29/hr
CPR Certification
10,000+

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Greater Endeavors
Healthcare & Veterinary Cleaning Specialist - Summerville/Mt. Pleasant
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Greater Endeavors
Added 4d ago
Healthcare & Veterinary Cleaning Specialist - Summerville/Mt. Pleasant
Greater Endeavors
Summerville, South Carolina
Healthcare Administration
Human Resources
Patient Services & Wellbeing
$12 - $18/hr
On-Site

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State of South Carolina
Healthcare Facility Inspector/Investigator (Investigations Unit) - 61151352
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State of South Carolina
Added 4d ago
Healthcare Facility Inspector/Investigator (Investigations Unit) - 61151352
State of South Carolina
Lexington County, SC
Civil Engineering
Construction
Construction Management
Engineering (Non-Software)
$52k - $54k/yr
Hybrid
Bachelor's degree in business administration
10,000+

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State of South Carolina
Healthcare Facility Inspector/Investigator (Hospitals and Professionals Section) - 61151122
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State of South Carolina
Added 4d ago
Healthcare Facility Inspector/Investigator (Hospitals and Professionals Section) - 61151122
State of South Carolina
Lexington County, SC
Civil Engineering
Construction
Construction Management
Engineering (Non-Software)
$52k - $54k/yr
Hybrid
Bachelor's degree in business administration
10,000+

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Healthcare Jobs by City in South Carolina

Where South Carolina roles are concentrated, by current openings.

Greenville
9 jobs
Sumter
8 jobs
North Charleston
7 jobs
Columbia
6 jobs
Greer
4 jobs
Spartanburg
4 jobs
Aiken
3 jobs
Charleston
3 jobs
West Columbia
3 jobs

Healthcare Job Market in South Carolina

A snapshot from current South Carolina openings, updated as new roles post.

Who's Hiring

  • Optum
    Optum11
  • State of South Carolina
    State of South Carolina11
  • Aveanna Healthcare
    Aveanna Healthcare8
  • First Priority Home Care
    First Priority Home Care7
  • Allied Universal
    Allied Universal5

Top Industries Hiring

  • Healthcare & Medical Services
  • Consulting & Professional Services
  • Insurance
  • Food & Beverage
  • Staffing & Recruiting

What South Carolina Employers Look For

The qualifications that appear most often in healthcare jobs across South Carolina.

  • Active South Carolina healthcare license or credential recognized by the South Carolina Board of Medical Examiners or relevant state board
  • Completed accredited degree or diploma program in a healthcare discipline
  • Current BLS or ACLS certification appropriate to the clinical setting
  • Minimum one to two years of experience in a relevant clinical or healthcare support role
  • Proficiency with electronic health record systems such as Epic or Cerner
  • Strong documentation skills and demonstrated knowledge of HIPAA compliance requirements

Healthcare Jobs in South Carolina: Frequently Asked Questions

How do you become a healthcare in South Carolina?

The path depends on your specific healthcare role, but most licensed positions in South Carolina require completing an accredited program, then applying to the relevant state board, such as the South Carolina Board of Nursing, the South Carolina Board of Medical Examiners, or the South Carolina Board of Long Term Health Care Administrators. Most boards require passing a national licensing exam before an active South Carolina license is issued. Credential requirements vary by role, so confirming with the applicable board before applying is the right first step.

Which companies hire healthcares in South Carolina?

Companies currently hiring healthcares in South Carolina include Optum, State of South Carolina, and Aveanna Healthcare, per current listings on Migrate Mate as of August 2026. South Carolina's largest hiring volume tends to come from integrated health systems anchored in Columbia, Charleston, and Greenville, alongside regional hospital networks and growing outpatient and home health providers.

Which South Carolina cities have the most healthcare jobs?

The cities with the most healthcare openings in South Carolina are Lexington County, Greenville, and Sumter. Columbia drives volume as the state capital and home to major systems like Prisma Health, while Charleston's concentration of MUSC Health facilities and academic medical centers anchors hiring in the Lowcountry, and Greenville's fast-growing population has made it one of the state's most active markets for outpatient and hospital-based roles.

Are there remote healthcare jobs in South Carolina?

Yes, but they're rare. Most healthcare work is hands-on and tied to a clinical site, so fully remote roles are the exception rather than the rule. About 77% of healthcare openings tied to South Carolina are remote or hybrid as of August 2026, and those positions tend to cluster in medical coding, health informatics, utilization review, and care coordination rather than direct patient care.

How can I get hired as a healthcare in South Carolina with little or no experience?

The most realistic entry path is applying directly to new-graduate or residency programs at large South Carolina health systems. Prisma Health and MUSC Health both run structured new-grad residencies for clinical roles, and Bon Secours regularly hires entry-level support and patient care technician positions that allow candidates to build clinical hours. Candidates moving from adjacent roles like medical assisting, phlebotomy, or certified nursing assistance find it easier to step into licensed roles once they complete required credentialing through the applicable South Carolina board.

Where can I find and apply to healthcare jobs in South Carolina?

You can find and apply to healthcare jobs in South Carolina on Migrate Mate, which lists current openings tied to the state. Search the roles available, find the ones that match your background and location, and apply directly to the ones that fit.

See All 85 Healthcare Jobs in South Carolina

Find roles in South Carolina that match your experience and apply in just a few clicks.

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