Nurse Navigator Jobs in South Carolina

Nurse Navigator jobs in South Carolina are concentrated in the state's major healthcare corridors, particularly Columbia, Greenville, and Charleston, where health systems like Prisma Health, MUSC Health, and Bon Secours hire consistently across oncology, cardiac, and complex chronic disease navigation. Demand runs from entry-level care coordination roles to senior navigators managing multidisciplinary service lines. South Carolina's growing population and expanding rural outreach programs have made oncology and post-acute navigation among the most active specialties in the state. See the openings below and apply to the ones that match your experience.

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Overview

Open roles5
Top employerBeaufort Memorial Hospital
Top cityBeaufort, SC
Cities hiring4
Top credentialBachelor's degree
Companies hiring4

Showing 5 of 5+ Nurse Navigator jobs

Nurse Navigator
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Nurse Navigator
Lexington Health
West Columbia, South Carolina
Healthcare Administration
Nursing
Patient Services & Wellbeing
CPR Certification
5,001-10,000

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Oncology Research & Clinical Trials Navigator Nurse
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Added 1mo ago
Oncology Research & Clinical Trials Navigator Nurse
Beaufort Memorial Hospital
Beaufort, South Carolina
Healthcare Administration
Nursing
Patient Services & Wellbeing
1,001-5,000

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Nurse Navigator
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Nurse Navigator
The START Center for Cancer Research
Myrtle Beach, South Carolina
Customer Service
Customer Support
Hospitality & Guest Services
Associate's degree
201-500

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Registered Nurse (RN) Certified Oncology Nurse Navigator, FT, Days
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Registered Nurse (RN) Certified Oncology Nurse Navigator, FT, Days
Prisma Health
Greenville, South Carolina
Healthcare Administration
Patient Services & Wellbeing
Social Work & Counseling
Bachelor's degree
10,000+

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Oncology GI / Pulmonary Nurse Navigator
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Added 3mo ago
Oncology GI / Pulmonary Nurse Navigator
Beaufort Memorial Hospital
Beaufort, South Carolina
Business Development
Events & Tourism
Executive Leadership & C-Suite
Project Management
1,001-5,000

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Nurse Navigator Jobs by City in South Carolina

Where South Carolina roles are concentrated, by current openings.

Beaufort
2 jobs
Greenville
1 job
Myrtle Beach
1 job
West Columbia
1 job

Nurse Navigator Job Market in South Carolina

A snapshot from current South Carolina openings, updated as new roles post.

Who's Hiring

Beaufort Memorial Hospital2 open roles
Prisma Health1 open role
Lexington Health1 open role

What South Carolina Employers Look For

The qualifications that appear most often in nurse navigator jobs across South Carolina.

  • Active registered nurse license recognized by the South Carolina Board of Nursing required
  • Associate or bachelor of science in nursing degree from an accredited program
  • Minimum two years of clinical nursing experience in a relevant specialty area
  • Oncology Certified Nurse or similar specialty certification preferred by most employers
  • Experience coordinating care across multidisciplinary teams in a hospital or health system
  • Proficiency with electronic health record systems such as Epic or Cerner

Nurse Navigator Jobs in South Carolina: Frequently Asked Questions

How do you become a nurse navigator in South Carolina?

Becoming a nurse navigator in South Carolina starts with holding an active registered nurse license issued or recognized by the South Carolina Board of Nursing, which requires passing the NCLEX-RN exam. Most employers then look for clinical experience in a specialty area such as oncology, cardiology, or chronic disease management before moving into a navigation role. Earning a specialty certification such as the Oncology Certified Nurse credential strengthens your candidacy considerably with South Carolina health systems.

How much do nurse navigators make in South Carolina?

Nurse navigators in South Carolina earn a median of about $82,360 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $66,860 for the lowest 10% to over $106,520 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire nurse navigators in South Carolina?

Companies currently hiring nurse navigators in South Carolina include Beaufort Memorial Hospital, Prisma Health, and Lexington Health, per current listings on Migrate Mate as of October 2026. South Carolina's largest health systems, including academic medical centers and regional hospital networks, generate the most consistent openings across oncology, cardiac, and complex care navigation programs.

Which South Carolina cities have the most nurse navigator jobs?

Beaufort, Greenville, and Myrtle Beach lead South Carolina in nurse navigator openings. Columbia anchors the market as the state capital and home to Prisma Health's flagship network, while Charleston's density of academic and specialty facilities at MUSC Health drives strong demand, and Greenville reflects the rapid population and system growth that Bon Secours Mercy Health has built across the Upstate region.

How can I get hired as a nurse navigator in South Carolina with little or no experience?

The most realistic entry path is building clinical experience in a specialty unit first, then applying internally. Large South Carolina health systems like Prisma Health and MUSC Health run new-graduate nurse residency programs that place RNs in oncology and cardiac units, which are the most common feeder departments for navigation roles. Lateral moves from case management, discharge planning, or care coordination positions are also common entry points. Holding or actively pursuing an RN license in South Carolina and gaining Epic documentation experience gives candidates a meaningful edge.

Where can I find and apply to nurse navigator jobs in South Carolina?

You can find and apply to nurse navigator jobs in South Carolina on Migrate Mate, which lists current openings from employers across the state. Search the listings, find the roles that match your experience and specialty background, and apply directly to the ones that fit.

See All 5 Nurse Navigator Jobs in South Carolina

Find roles in South Carolina that match your experience and apply in just a few clicks.

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