Nurse Navigator Jobs in South Carolina
Nurse Navigator jobs in South Carolina are concentrated in the state's major healthcare corridors, particularly Columbia, Greenville, and Charleston, where health systems like Prisma Health, MUSC Health, and Bon Secours hire consistently across oncology, cardiac, and complex chronic disease navigation. Demand runs from entry-level care coordination roles to senior navigators managing multidisciplinary service lines. South Carolina's growing population and expanding rural outreach programs have made oncology and post-acute navigation among the most active specialties in the state. See the openings below and apply to the ones that match your experience.
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Quality Management-Ambulatory
Full Time
Day Shift
0800-1630
Sign-On Bonus: up to $10,000
Lexington Health is a comprehensive network of care that includes six community medical and urgent care centers, nearly 80 physician practices, more than 9,000 health care professionals and Lexington Medical Center, a 607-bed teaching hospital in West Columbia, South Carolina. It was selected by Modern Healthcare as one of the Best Places to Work in Healthcare and was first in the state to achieve Magnet with Distinction status for excellence in nursing care. Consistently ranked as best in the Columbia Metro area by U.S. News & World Report, Lexington Health delivers more than 4,000 babies each year, performs more than 34,000 surgeries annually and is the region's third largest employer.
Lexington Health also includes an accredited Cancer Center of Excellence, the state’s first HeartCARE Center, the largest skilled nursing facility in the Carolinas, and an Alzheimer’s care center. Its postgraduate medical education programs include family medicine and transitional year residencies, as well as an informatics fellowship.
Job Summary
The Nurse Navigator is responsible for the operational functions of a specific navigation program. Using clinical, administrative, research and educational standards, the Nurse Navigator facilitates the coordination of care for patients through the continuum based on their diagnosis or procedure which may include but is not limited to ensuring follow up with physician offices, scheduling of necessary diagnostic procedures providing education and emotional support throughout the path of care or designated timeframe. All responsibilities are carried out in accordance with the mission, vision, strategic imperatives and standards of the Lexington County Health District, American Nurses Association standards and in accordance with the provisions set forth by the SC Nurse Practice Act.
Minimum Qualifications
Minimum Education: Bachelors of Science in Nursing (BSN)
Minimum Years of Experience: 2 Years in Area of Interest.
Substitutable Education & Experience (Optional): In lieu of a Bachelor’s of Science in Nursing (BSN), will consider those with Diploma or Associate's Degree in Nursing (ADN) with an additional 2 years of experience in Area of Interest
Required Certifications/Licensure: Current RN license to practice in the state of S.C.; Certification in CPR.
Required Training: None.
Essential Functions
- Works in a cooperative manner, which fosters relations between employees and patients, patients’ families, visitors, fellow employees, and the medical staff.
- Accepts the chain of command, supervision, and constructive criticism.
- Exhibits commitment and pride through personal example by positively speaking about LMC, the department, employees and guests.
- Contributes to teamwork and creates harmonious, effective and positive working relationships with others.
- Respects, understands, and responds with sensitivity to employees and guests by treating others as one would wish to be treated.
- Resolves conflicts and problems-solves by remaining calm when confronted, attempting to identify solutions or referring person to appropriate authority and attempting to deliver more than is expected.
- Exhibits telephone courtesy by:
- a. Answering promptly with name and department.
- b. Speaking with pleasant tone while focusing on caller.
- c. Transferring calls correctly and promptly.
- d. Attending to calls on hold in a timely manner
- Maintains confidentiality by:
- a. Discouraging gossip.
- b. Using discretion when discussing patient, work, or LMC-related information with others.
- Utilizes the service recovery process to resolve complaints (GIFT).
- Coordinates, monitors and role models the delivery of care to specified patients in the outpatient setting by incorporating process improvement initiatives to achieve desired outcomes for patients and their significant others.
- Receives and triages new referrals to the program.
- Coordinates the scheduling of outpatient appointments to ensure and smooth and timely flow of care.
- As indicated by referring physician, performs preliminary telephone assessment of patient to include pertinent history and current chief complaints. Assesses demographic and health status data for potential referrals to Social Services, Nutrition Services, support groups, etc.
- Acts as a patient advocate
- Assesses patient’s understanding of their diagnosis and therapeutic options and intervenes or makes referrals as necessary.
- Assesses patient satisfaction with program framework, processes, and outcomes.
- Provides assistance to patients by means of ongoing patient education to facilitate optimal understanding of health regimens.
- Serves as a facilitator for support groups when needed and provides educational offerings.
- Meets the area and age-specific requirements, appropriate to the designated adult patient population.
- Contributes to LMC’s arena of excellence by demonstrating behaviors conducive to growth and development within the practice of nursing.
- Maintains patient confidentiality and respects patient privacy and Patient’s Bill of Rights.
- Demonstrates knowledge of organizational initiatives and assists in attainment of goals as appropriate.
- In pursuit of excellence and service, demonstrates desire and effort to be a role model as evidenced by the following:
- a. Identifies self-development opportunities.
- b. Earns at least 25 hours of continuing education annually.
- c. Demonstrates and maintains competence in clinical area.
- d. Establishes measurable goals.
- e. Serves as community ambassador and educational speaker on relevant health issues and topics when needed.
- Evaluates, selects, utilizes, and accounts for material resources with appropriate consideration for patient needs, hospital policies and procedures and budgetary constraints in collaboration with department leader.
- Evaluates potential outcomes relative to resource utilization in collaboration with department leader.
Duties & Responsibilities
- Identifies and evaluates product needs in collaboration with department leader.
- Collaborates with physicians and ancillary services regarding coordination of care to facilitate cost effectiveness.
- Provides input into selection of equipment and materials. Utilizes equipment and resources efficiently.
- Participates in the identification of appropriate educational programs for patients and staff development and collaborates with appropriate departments to meet these needs.
- Effectively uses electronic, verbal, non-verbal, written, and interpersonal communication skills in a clear and concise manner to ensure appropriate understanding and response.
- Serves as a liaison for providers within the program framework.
- Communicates effectively with other health care team members.
- Demonstrates timely communication of unexpected patient events/issues to appropriate persons.
- Keeps physicians and other health care team members informed of program activities.
- Maintains required records, database, and reports.
- Participates in regular patient care conferences with patient care team to plan multidisciplinary treatment.
- Teaches patient and family in an understandable manner, information needed for the patient to be able to manage self-care or family-supported care.
- Communicates with peers to share knowledge and skills.
- Communicates using the chain of command when mutual understanding and/or consensus on patient care or operational issues are not achieved.
- Performance Improvement: Identifies opportunities to improve patient care, health care practice, and interaction with healthcare partners; and initiates and/or participates in development of action plans to achieve desired outcomes in collaboration with department leader.
- Participates in quality assessment and improvement activities within the organization and department.
- Participates in interdisciplinary monitoring and evaluation of patient care.
- Serves as a task force member when needed to improve processes.
- Assesses provider satisfaction with program framework, processes, and outcomes.
- Demonstrates responsibility for achievement of identified patient outcomes.
- Identifies opportunities for system improvement that enhance the delivery of patient centered care.
- Demonstrates competence to provide care for the designated patient population.
- Meets all requirements as defined by LMC policies.
- Completes yearly safety training and other mandatory classes.
- Completes employee health workup.
- Meets department attendance requirements.
- Maintains current RN licensure.
- Ensure Hazardous Waste or Hazardous Waste Pharmaceuticals are discarded, stored, and managed with other compatible waste streams in containers that are properly labeled and closed prior to being shipped offsite for proper disposal. Initial RCRA training is received within 6 months of the hire date and continuing with annual RCRA training.
- Performs all other duties as assigned.
We are committed to offering quality, cost-effective benefits choices for our benefit eligible employees and their families:
- Day ONE medical, dental and life insurance benefits
- Health care and dependent care flexible spending accounts (FSAs)
- Employees are eligible for enrollment into the 403(b) match plan day one. LHI matches dollar for dollar up to 6%.
- Employer paid life insurance – equal to 1x salary
- Employee may elect supplemental life insurance with low cost premiums up to 3x salary
- Adoption assistance
- LHI provides its full-time employees employer paid short-term disability and long-term disability coverage after 90 days of eligible employment
- Tuition reimbursement
- Student loan forgiveness
Equal Opportunity Employer
It is the policy of Lexington Health to provide equal opportunity of employment for all individuals, and to remain compliant with applicable state and federal laws and regulations. Lexington Health strives to provide a discrimination-free environment, and to recruit, select, on-board, and employ all employees without regard to race, color, religion, sex, age, disability, national origin, veteran status, or pregnancy, childbirth, or related medical conditions, including but not limited to, lactation. Lexington Health endeavors to upgrade and promote employees from within the hospital where possible and consistent with the employee’s desires and abilities and the hospital’s needs.
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Where South Carolina roles are concentrated, by current openings.
Nurse Navigator Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring



What South Carolina Employers Look For
The qualifications that appear most often in nurse navigator jobs across South Carolina.
- Active registered nurse license recognized by the South Carolina Board of Nursing required
- Associate or bachelor of science in nursing degree from an accredited program
- Minimum two years of clinical nursing experience in a relevant specialty area
- Oncology Certified Nurse or similar specialty certification preferred by most employers
- Experience coordinating care across multidisciplinary teams in a hospital or health system
- Proficiency with electronic health record systems such as Epic or Cerner
Nurse Navigator Jobs in South Carolina: Frequently Asked Questions
How do you become a nurse navigator in South Carolina?
Becoming a nurse navigator in South Carolina starts with holding an active registered nurse license issued or recognized by the South Carolina Board of Nursing, which requires passing the NCLEX-RN exam. Most employers then look for clinical experience in a specialty area such as oncology, cardiology, or chronic disease management before moving into a navigation role. Earning a specialty certification such as the Oncology Certified Nurse credential strengthens your candidacy considerably with South Carolina health systems.
How much do nurse navigators make in South Carolina?
Nurse navigators in South Carolina earn a median of about $82,360 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $66,860 for the lowest 10% to over $106,520 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire nurse navigators in South Carolina?
Companies currently hiring nurse navigators in South Carolina include Beaufort Memorial Hospital, Prisma Health, and Lexington Health, per current listings on Migrate Mate as of October 2026. South Carolina's largest health systems, including academic medical centers and regional hospital networks, generate the most consistent openings across oncology, cardiac, and complex care navigation programs.
Which South Carolina cities have the most nurse navigator jobs?
Beaufort, Greenville, and Myrtle Beach lead South Carolina in nurse navigator openings. Columbia anchors the market as the state capital and home to Prisma Health's flagship network, while Charleston's density of academic and specialty facilities at MUSC Health drives strong demand, and Greenville reflects the rapid population and system growth that Bon Secours Mercy Health has built across the Upstate region.
How can I get hired as a nurse navigator in South Carolina with little or no experience?
The most realistic entry path is building clinical experience in a specialty unit first, then applying internally. Large South Carolina health systems like Prisma Health and MUSC Health run new-graduate nurse residency programs that place RNs in oncology and cardiac units, which are the most common feeder departments for navigation roles. Lateral moves from case management, discharge planning, or care coordination positions are also common entry points. Holding or actively pursuing an RN license in South Carolina and gaining Epic documentation experience gives candidates a meaningful edge.
Where can I find and apply to nurse navigator jobs in South Carolina?
You can find and apply to nurse navigator jobs in South Carolina on Migrate Mate, which lists current openings from employers across the state. Search the listings, find the roles that match your experience and specialty background, and apply directly to the ones that fit.
See All 5 Nurse Navigator Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
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