Mental Health Nurse Practitioner Jobs in South Carolina
Mental Health Nurse Practitioner jobs in South Carolina are concentrated in Columbia, Greenville, and Charleston, where demand for psychiatric and behavioral health specialists remains strong across inpatient facilities, community mental health centers, and integrated primary care settings. Major employers with lasting presences in the state include Prisma Health, MUSC Health, and the South Carolina Department of Mental Health. The most sought-after specialties are child and adolescent psychiatry, substance use disorder treatment, and telehealth-based outpatient care. Find a role that fits below and apply directly.
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Showing 5 of 6+ Mental Health Nurse Practitioner jobs
[We show compassion to heal minds.]
About Legion Health
Legion Health is a technology-forward psychiatry company delivering world-class outpatient mental health care while expanding access for patients through insurance.
We are seeking exceptional Psychiatric Mental Health Nurse Practitioners (PMHNPs) across the United States who are passionate about evidence-based psychiatry and want the time, support, and clinical autonomy needed to provide exceptional patient care.
Our innovative model combines the stability of a traditional hospital position with the flexibility of a private practice. We prioritize our clinicians' well-being and professional growth, offering a competitive compensation package and fostering a vibrant, collaborative culture.
Quality and patient experience are paramount to us. This means recruiting exceptional providers, championing evidence-based protocols, and displaying compassion in every patient interaction. Our exceptional PMHNPs operate with clinical autonomy, supported by experienced psychiatrists through consults and peer case reviews.
Our vision is to pioneer a new era of medicine by delivering world-class psychiatry. We believe in a future where every person can access the compassionate, high-quality care they need.
About the Role
Practice at the top of your license, from wherever you do your best work. This role is designed for PMHNPs who want meaningful clinical autonomy without having to build and operate a private practice alone.
We are looking for clinically excellent, patient-centered PMHNPs to provide psychiatric care through telehealth. Full-time and part-time positions are available.
Benefits
Legion’s model is built to give clinicians more time for patients, fewer administrative distractions, and the support of a high-caliber psychiatric community.
Flexibility: Set your own schedule for optimal work-life balance.
Work from Home: See patients from the comfort of your home via telehealth.
Significant Administrative Support: You focus on patient care, and we’ll handle scheduling, insurance verification, billing, prior authorizations, pharmacy coordination, etc.
Patient Acquisition: Unlike with a private practice, we’ll work to fill your schedule, so you don’t have to do your own marketing.
Collaborating Physician Coverage: Where applicable, we provide your collaborating psychiatrist and fully cover the costs.
Competitive Pay: We compensate our providers at market-leading rates.
Weekly Pay: We pay our providers every week for immediate financial benefit and planning ease.
Legal Protection: We provide full malpractice insurance coverage.
Clinical Autonomy: We hire the most skilled providers and trust them to do what’s best for patients.
Technical Support: We cover the costs for you to have best-in-class EHR, e-Prescribe, and AI tools.
Credentialing Support: We handle all aspects and costs of credentialing with a large number of insurance plans, including commercial, ACA, and government, ensuring your legal and effective authorization within insurance networks.
Licensure and DEA Coverage: We’ll reimburse you for all fees associated with getting licensed in other states as required by Legion.
Commitment to Responsible Prescribing and High-Quality Care: We have rigorous, evidence-based protocols and provide objective diagnostic tools to ensure responsible and ethical prescriptions of controlled substances.
Community of Clinical Excellence: You will work alongside the most talented PMHNPs and psychiatrists in the world. Our current PMHNPs have trained at some of the country’s most prestigious institutions, including Vanderbilt, UT Austin, Johns Hopkins, Columbia, NYU, and UTHealth Houston.
Opportunities for Professional Growth: As we expand, we intend to promote clinical leadership from the best of our active providers.
Culture of Excellence through Innovation: Actively participate in ushering in a new era of mental health care through superior clinical care and technology.
Resources: We provide premium subscriptions to resources such as UpToDate and Carlat.
Exclusive Events: Engage with your colleagues through exclusive in-person and virtual events.
Responsibilities
Provide excellent patient care for conditions including depression, anxiety, ADHD, insomnia, PTSD, bipolar disorder, etc.
Perform comprehensive psychiatric assessments, including mental-health history, medical history, diagnostic evaluation, and risk analysis.
Create and execute individualized treatment plans that may combine medication management and brief psychotherapy.
Provide compassionate, respectful, and patient-centered care.
Use evidence-based clinical protocols and responsible prescribing practices.
Collaborate with psychiatrists and clinical peers through consultations and case reviews.
Use technology and operational systems effectively to deliver reliable telehealth care.
Qualifications
Active, unrestricted state-issued authority to practice as a PMHNP in at least one U.S. state or jurisdiction.
Strong clinical assessment, diagnostic, and medication-management skills.
Excellent communication and interpersonal skills.
Comfort providing care remotely and using electronic health record systems.
Commitment to patient-centered, compassionate, evidence-based care.
Role Logistics
Location: Fully remote within the United States.
Schedule: Full-time or part-time positions are available.
Compensation: $150K–$300K per year, depending on completed patient-care hours.
Clinical Advisory Board
Legion’s Clinical Advisory Board brings together nationally recognized psychiatrists, physician executives, telepsychiatry pioneers, and primary-care leaders. Working closely with Legion’s medical leadership, they help shape our clinical quality standards, evidence-based care protocols, prescribing safeguards, risk-management practices, and continuous quality-improvement efforts as the company scales.
Members of our Clinical Advisory Board include:
Madhukar Trivedi, M.D. — Psychiatrist; Professor of Psychiatry and Distinguished Chair in Mental Health at UT Southwestern
Alexander Ruvalcaba, M.D. — Psychiatrist; Physician Executive at MultiCare Behavioral Health Network
Jon Kole, M.D. — Psychiatrist; Senior Medical Director at Headspace
Liberty Eberly, D.O. — Psychiatrist; Co-Founder and Former Chief Medical Officer at innovaTel Telepsychiatry
John Lusins, M.D. — Psychiatrist; Founder and President at South Texas Mental Health Associates
Jacqueline Champlain, M.D. — Family Medicine Physician; Lead Physician at WellMed and Fellow of the American Academy of Family Physicians
Bring Your Best Clinical Work to Legion
If you are a thoughtful, evidence-based PMHNP who wants the flexibility of remote practice, meaningful clinical autonomy, robust operational support, and a community committed to excellent psychiatric care, we would be excited to learn more about you.
Equal Employment Opportunity
Legion Health is proud to be an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees, contractors, and applicants without regard to race, color, religion, sex, sexual orientation, gender identity or expression, national origin, age, disability, veteran status, genetic information, or any other protected characteristic under applicable law. We encourage applicants from all backgrounds to apply.
Compensation Range: $150K - $300K
[We show compassion to heal minds.]
About Legion Health
Legion Health is a technology-forward psychiatry company delivering world-class outpatient mental health care while expanding access for patients through insurance.
We are seeking exceptional Psychiatric Mental Health Nurse Practitioners (PMHNPs) across the United States who are passionate about evidence-based psychiatry and want the time, support, and clinical autonomy needed to provide exceptional patient care.
Our innovative model combines the stability of a traditional hospital position with the flexibility of a private practice. We prioritize our clinicians' well-being and professional growth, offering a competitive compensation package and fostering a vibrant, collaborative culture.
Quality and patient experience are paramount to us. This means recruiting exceptional providers, championing evidence-based protocols, and displaying compassion in every patient interaction. Our exceptional PMHNPs operate with clinical autonomy, supported by experienced psychiatrists through consults and peer case reviews.
Our vision is to pioneer a new era of medicine by delivering world-class psychiatry. We believe in a future where every person can access the compassionate, high-quality care they need.
About the Role
Practice at the top of your license, from wherever you do your best work. This role is designed for PMHNPs who want meaningful clinical autonomy without having to build and operate a private practice alone.
We are looking for clinically excellent, patient-centered PMHNPs to provide psychiatric care through telehealth. Full-time and part-time positions are available.
Benefits
Legion’s model is built to give clinicians more time for patients, fewer administrative distractions, and the support of a high-caliber psychiatric community.
Flexibility: Set your own schedule for optimal work-life balance.
Work from Home: See patients from the comfort of your home via telehealth.
Significant Administrative Support: You focus on patient care, and we’ll handle scheduling, insurance verification, billing, prior authorizations, pharmacy coordination, etc.
Patient Acquisition: Unlike with a private practice, we’ll work to fill your schedule, so you don’t have to do your own marketing.
Collaborating Physician Coverage: Where applicable, we provide your collaborating psychiatrist and fully cover the costs.
Competitive Pay: We compensate our providers at market-leading rates.
Weekly Pay: We pay our providers every week for immediate financial benefit and planning ease.
Legal Protection: We provide full malpractice insurance coverage.
Clinical Autonomy: We hire the most skilled providers and trust them to do what’s best for patients.
Technical Support: We cover the costs for you to have best-in-class EHR, e-Prescribe, and AI tools.
Credentialing Support: We handle all aspects and costs of credentialing with a large number of insurance plans, including commercial, ACA, and government, ensuring your legal and effective authorization within insurance networks.
Licensure and DEA Coverage: We’ll reimburse you for all fees associated with getting licensed in other states as required by Legion.
Commitment to Responsible Prescribing and High-Quality Care: We have rigorous, evidence-based protocols and provide objective diagnostic tools to ensure responsible and ethical prescriptions of controlled substances.
Community of Clinical Excellence: You will work alongside the most talented PMHNPs and psychiatrists in the world. Our current PMHNPs have trained at some of the country’s most prestigious institutions, including Vanderbilt, UT Austin, Johns Hopkins, Columbia, NYU, and UTHealth Houston.
Opportunities for Professional Growth: As we expand, we intend to promote clinical leadership from the best of our active providers.
Culture of Excellence through Innovation: Actively participate in ushering in a new era of mental health care through superior clinical care and technology.
Resources: We provide premium subscriptions to resources such as UpToDate and Carlat.
Exclusive Events: Engage with your colleagues through exclusive in-person and virtual events.
Responsibilities
Provide excellent patient care for conditions including depression, anxiety, ADHD, insomnia, PTSD, bipolar disorder, etc.
Perform comprehensive psychiatric assessments, including mental-health history, medical history, diagnostic evaluation, and risk analysis.
Create and execute individualized treatment plans that may combine medication management and brief psychotherapy.
Provide compassionate, respectful, and patient-centered care.
Use evidence-based clinical protocols and responsible prescribing practices.
Collaborate with psychiatrists and clinical peers through consultations and case reviews.
Use technology and operational systems effectively to deliver reliable telehealth care.
Qualifications
Active, unrestricted state-issued authority to practice as a PMHNP in at least one U.S. state or jurisdiction.
Strong clinical assessment, diagnostic, and medication-management skills.
Excellent communication and interpersonal skills.
Comfort providing care remotely and using electronic health record systems.
Commitment to patient-centered, compassionate, evidence-based care.
Role Logistics
Location: Fully remote within the United States.
Schedule: Full-time or part-time positions are available.
Compensation: $150K–$300K per year, depending on completed patient-care hours.
Clinical Advisory Board
Legion’s Clinical Advisory Board brings together nationally recognized psychiatrists, physician executives, telepsychiatry pioneers, and primary-care leaders. Working closely with Legion’s medical leadership, they help shape our clinical quality standards, evidence-based care protocols, prescribing safeguards, risk-management practices, and continuous quality-improvement efforts as the company scales.
Members of our Clinical Advisory Board include:
Madhukar Trivedi, M.D. — Psychiatrist; Professor of Psychiatry and Distinguished Chair in Mental Health at UT Southwestern
Alexander Ruvalcaba, M.D. — Psychiatrist; Physician Executive at MultiCare Behavioral Health Network
Jon Kole, M.D. — Psychiatrist; Senior Medical Director at Headspace
Liberty Eberly, D.O. — Psychiatrist; Co-Founder and Former Chief Medical Officer at innovaTel Telepsychiatry
John Lusins, M.D. — Psychiatrist; Founder and President at South Texas Mental Health Associates
Jacqueline Champlain, M.D. — Family Medicine Physician; Lead Physician at WellMed and Fellow of the American Academy of Family Physicians
Bring Your Best Clinical Work to Legion
If you are a thoughtful, evidence-based PMHNP who wants the flexibility of remote practice, meaningful clinical autonomy, robust operational support, and a community committed to excellent psychiatric care, we would be excited to learn more about you.
Equal Employment Opportunity
Legion Health is proud to be an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees, contractors, and applicants without regard to race, color, religion, sex, sexual orientation, gender identity or expression, national origin, age, disability, veteran status, genetic information, or any other protected characteristic under applicable law. We encourage applicants from all backgrounds to apply.
Compensation Range: $150K - $300K
See All 6 Mental Health Nurse Practitioner Jobs in South Carolina
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Find JobsMental Health Nurse Practitioner Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Mental Health Nurse Practitioner Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring
What South Carolina Employers Look For
The qualifications that appear most often in mental health nurse practitioner jobs across South Carolina.
- Active South Carolina APRN license with psychiatric-mental health nurse practitioner certification required
- Current national PMHNP-BC certification from ANCC or equivalent certifying body
- Master of Science in Nursing or Doctor of Nursing Practice in psychiatric-mental health
- Prescriptive authority registration with the South Carolina Board of Nursing
- Experience conducting psychiatric evaluations, diagnosing disorders, and managing psychotropic medications
- Familiarity with electronic health records platforms and collaborative care documentation standards
Mental Health Nurse Practitioner Jobs in South Carolina: Frequently Asked Questions
How do you become a mental health nurse practitioner in South Carolina?
You must earn a graduate degree in nursing with a psychiatric-mental health nurse practitioner concentration, then pass the ANCC PMHNP-BC board certification exam. After that, you apply to the South Carolina Board of Nursing for APRN licensure and register for prescriptive authority in the state. South Carolina operates under a collaborative practice agreement model, so new practitioners typically work with a collaborating physician until they meet the experience threshold to practice more independently.
How much do mental health nurse practitioners make in South Carolina?
Mental health nurse practitioners in South Carolina earn a median of about $123,290 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $97,080 for the lowest 10% to over $160,170 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire mental health nurse practitioners in South Carolina?
Employers hiring mental health nurse practitioners in South Carolina right now include BEACON BEHAVIORAL SUPPORT SERVICES, Legion Health, and Recovery Centers of America, based on current listings on Migrate Mate as of August 2026. South Carolina's large integrated health systems and the state's public behavioral health network both maintain consistent hiring pipelines for this specialty.
Which South Carolina cities have the most mental health nurse practitioner jobs?
Greenville, Greer, and Seneca have the most mental health nurse practitioner openings in South Carolina. Columbia leads as the state capital and home to MUSC Health's behavioral health services and the South Carolina Department of Mental Health's central operations, while Greenville and Charleston drive demand through rapidly growing regional hospital systems and expanding outpatient behavioral health clinics.
Are there remote mental health nurse practitioner jobs in South Carolina?
Yes, but they are limited compared to purely desk-based fields because psychiatric evaluations and medication management often require in-person or secure telehealth encounters. About 100% of mental health nurse practitioner openings tied to South Carolina are remote or hybrid as of August 2026. The roles most likely to offer full telehealth schedules are outpatient therapy management and medication follow-up positions with established behavioral health telehealth networks.
How can I get hired as a mental health nurse practitioner in South Carolina with little or no experience?
The most realistic entry path is a new-graduate or residency fellowship program, and Prisma Health and MUSC Health both run structured APRN residencies that accept newly certified PMHNPs. Candidates without direct PMHNP experience can also pursue lateral moves from roles like registered psychiatric nurse or inpatient behavioral health RN at South Carolina Department of Mental Health facilities. Completing your South Carolina collaborative practice agreement with a supervising psychiatrist and holding a clean APRN license puts you ahead of candidates still awaiting credentialing.
Where can I find and apply to mental health nurse practitioner jobs in South Carolina?
You can find and apply to mental health nurse practitioner jobs in South Carolina on Migrate Mate, which lists current openings across the state. Search the listings, find roles that match your credentials and preferred setting, and apply directly to the employers posting them.
See All 6 Mental Health Nurse Practitioner Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
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