Physical Therapy Assistant Jobs in South Carolina

Physical Therapy Assistant jobs in South Carolina are in strong demand, concentrated in outpatient orthopedic clinics, hospital rehabilitation units, skilled nursing facilities, and home health agencies, with openings available from entry-level to senior clinician. The heaviest hiring activity runs through Columbia, Greenville, and Charleston, where established employers like Prisma Health, MUSC Health, and Encompass Health maintain ongoing PTA staffing needs. The most sought-after specialties in the state include orthopedic rehabilitation, geriatric care, and neurological recovery. See the openings below and apply to the ones that match your experience.

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Overview

Open roles79
Top employerATI Physical Therapy
Top cityGreenville, SC
Cities hiring42
Work type100% On-site
Top industryHealthcare

Showing 5 of 79+ Physical Therapy Assistant jobs

Legacy Healthcare Services
Physical Therapy Assistant
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Legacy Healthcare Services
Added 1d ago
Physical Therapy Assistant
Legacy Healthcare Services
Spartanburg, South Carolina
Executive Leadership & C-Suite
Program Management
Project Management
Associate of Applied Science
1,001-5,000

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PruittHealth
Physical Therapy Assistant
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PruittHealth
Added 2d ago
Physical Therapy Assistant
PruittHealth
Estill, South Carolina
Allied Health
Physical Therapy
On-Site
Associate's
10,000+

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Advocate Aurora Health
Physical Therapy Assistant - Atrium Health Neurosurgery and Spine - Outpatient - Rock Hill - FT
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Advocate Aurora Health
Added 2d ago
Physical Therapy Assistant - Atrium Health Neurosurgery and Spine - Outpatient - Rock Hill - FT
Advocate Aurora Health
Rock Hill, South Carolina
Healthcare Administration
Medical Assistant
Patient Services & Wellbeing
$24.1 - $36.15/hr
Associate's degree in physical therapist assistant
10,000+

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Powerback Rehabilitation
Physical Therapy Assistant (PTA)
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Powerback Rehabilitation
Added 2d ago
Physical Therapy Assistant (PTA)
Powerback Rehabilitation
Simpsonville, South Carolina
Customer Service
Customer Support
Hospitality & Guest Services
$33 - $35/hr
5,001-10,000

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ATI Physical Therapy
Physical Therapy Aide
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ATI Physical Therapy
Added 2d ago
Physical Therapy Aide
ATI Physical Therapy
Boiling Springs, South Carolina
Maintenance & Repair
Quality Control
Skilled Trades
On-Site
High school diploma or GED
5,001-10,000

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See All 79 Physical Therapy Assistant Jobs in South Carolina

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Physical Therapy Assistant Jobs by City in South Carolina

Where South Carolina roles are concentrated, by current openings.

Greenville
8 jobs
Columbia
7 jobs
Aiken
4 jobs
Greer
3 jobs
Cheraw
3 jobs
Florence
3 jobs
Rock Hill
3 jobs
Spartanburg
3 jobs
Johns Island
3 jobs

Physical Therapy Assistant Job Market in South Carolina

A snapshot from current South Carolina openings, updated as new roles post.

Who's Hiring

ATI Physical Therapy
ATI Physical Therapy9 open roles
McLeod Health
McLeod Health7 open roles
The Weston
The Weston6 open roles

Top Industries Hiring

  • Healthcare & Medical Services

What South Carolina Employers Look For

The qualifications that appear most often in physical therapy assistant jobs across South Carolina.

  • Active South Carolina physical therapy assistant license issued by the SC Board of Physical Therapy Examiners
  • Graduate of an accredited physical therapist assistant program with an Associate of Applied Science degree
  • Current APTA-recognized certification or passage of the NPTE-PTA licensing examination
  • Minimum one to two years of clinical experience in outpatient or inpatient rehabilitation settings
  • Current CPR and Basic Life Support certification required at hire or within specified onboarding period
  • Strong documentation skills and proficiency with electronic health records systems such as WebPT or Raintree

Physical Therapy Assistant Jobs in South Carolina: Frequently Asked Questions

How do you become a physical therapy assistant in South Carolina?

You must complete an accredited physical therapist assistant program, typically a two-year Associate of Applied Science degree, and then pass the National Physical Therapy Examination for PTAs. After passing the exam, you apply for licensure through the South Carolina Board of Physical Therapy Examiners, which requires submitting proof of education, exam results, and a completed application. South Carolina does not participate in the PTA Licensure Compact, so out-of-state PTAs must apply for a full South Carolina license.

Which companies hire physical therapy assistants in South Carolina?

Companies currently hiring physical therapy assistants in South Carolina include ATI Physical Therapy, McLeod Health, and The Weston, per current listings on Migrate Mate as of August 2026. South Carolina's large health systems and post-acute care networks consistently post PTA openings across the state's major metropolitan and rural service areas.

Which South Carolina cities have the most physical therapy assistant jobs?

Greenville, Columbia, and Aiken have the most physical therapy assistant openings in South Carolina. Columbia leads as the state capital with a high concentration of hospital systems and outpatient clinics, while Greenville's growing Upstate health corridor and Charleston's strong medical and retirement community base drive consistent demand in those metros.

Are there remote physical therapy assistant jobs in South Carolina?

Yes, but they're rare. Physical therapy assistant work is hands-on by nature, requiring direct patient contact for exercises, manual techniques, and functional assessments. About 0% of physical therapy assistant openings tied to South Carolina are remote or hybrid as of August 2026, and those positions are almost exclusively limited to documentation review, telehealth care coordination, or administrative support roles within larger rehabilitation organizations.

How can I get hired as a physical therapy assistant in South Carolina with little or no experience?

The most realistic entry path is applying to new-graduate positions at large South Carolina health systems like Prisma Health or MUSC Health, which regularly hire recent PTA graduates into supervised clinical roles. Candidates who worked as rehab aides or physical therapy technicians during school hold a real advantage, since that hands-on background translates directly. Completing your South Carolina licensure promptly after graduation and targeting skilled nursing facilities or outpatient orthopedic clinics, which tend to onboard new PTAs more readily than acute hospital settings, will strengthen your candidacy.

Where can I find and apply to physical therapy assistant jobs in South Carolina?

You can find and apply to physical therapy assistant jobs in South Carolina on Migrate Mate, which lists current openings across the state. Search the listings to find roles that fit your experience level, specialty, and preferred location, then apply directly to the ones that match.

See All 79 Physical Therapy Assistant Jobs in South Carolina

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