Physical Therapy Assistant Jobs in South Carolina
Physical Therapy Assistant jobs in South Carolina are in strong demand, concentrated in outpatient orthopedic clinics, hospital rehabilitation units, skilled nursing facilities, and home health agencies, with openings available from entry-level to senior clinician. The heaviest hiring activity runs through Columbia, Greenville, and Charleston, where established employers like Prisma Health, MUSC Health, and Encompass Health maintain ongoing PTA staffing needs. The most sought-after specialties in the state include orthopedic rehabilitation, geriatric care, and neurological recovery. See the openings below and apply to the ones that match your experience.
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- Share your skills and training as a valued member of our on-site rehabilitative care team by assisting with rehabilitative services for patients under specific medical orders as part of a coordinated team.
- Provide attentive one-on-one therapy services for residents, administering functional treatments that emphasize a holistic, patient-centered approach to care.
- Get mentorship and valuable hands-on experience utilizing innovative technologies and therapeutic treatments.
- Advance your career, pursue clinical interests, and develop subject matter expertise.
- Desirable Monday–Friday schedule with no weekend or holiday requirements
- 401(k)
- Medical/dental/vision/prescription/pet insurance
- Paid time off (PTO) with rollover and buyout options at year’s end
- Company-paid group life
- Flex spending account
- Voluntary life, short-term disability, and long-term disability insurance
- Licensure reimbursement
- Company-provided CEUs and unlimited online CEUs for full-time employees
- Career advancement opportunities
Discover what makes Legacy Healthcare Services different::
- Our not-for-profit organization offers personalized therapeutic care for residents within senior living communities, offering rehabilitative care that helps improve their quality of life.
- Our organization was founded by and continues to be led by therapists.
- We are one of the largest providers of on-site senior therapy care in the country, serving nearly 500 senior living communities throughout the U.S. and growing!
- We are leaders in innovation and personalized care, which makes us a preferred provider for senior adults residing in the communities we serve.
- Associate’s of applied science degree in area of discipline
- Current license in state of practice
- Excellent interpersonal, fiscal, and clinical skills
- Computer proficiency
See All 79 Physical Therapy Assistant Jobs in South Carolina
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Find JobsPhysical Therapy Assistant Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Physical Therapy Assistant Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Healthcare & Medical Services
What South Carolina Employers Look For
The qualifications that appear most often in physical therapy assistant jobs across South Carolina.
- Active South Carolina physical therapy assistant license issued by the SC Board of Physical Therapy Examiners
- Graduate of an accredited physical therapist assistant program with an Associate of Applied Science degree
- Current APTA-recognized certification or passage of the NPTE-PTA licensing examination
- Minimum one to two years of clinical experience in outpatient or inpatient rehabilitation settings
- Current CPR and Basic Life Support certification required at hire or within specified onboarding period
- Strong documentation skills and proficiency with electronic health records systems such as WebPT or Raintree
Physical Therapy Assistant Jobs in South Carolina: Frequently Asked Questions
How do you become a physical therapy assistant in South Carolina?
You must complete an accredited physical therapist assistant program, typically a two-year Associate of Applied Science degree, and then pass the National Physical Therapy Examination for PTAs. After passing the exam, you apply for licensure through the South Carolina Board of Physical Therapy Examiners, which requires submitting proof of education, exam results, and a completed application. South Carolina does not participate in the PTA Licensure Compact, so out-of-state PTAs must apply for a full South Carolina license.
Which companies hire physical therapy assistants in South Carolina?
Companies currently hiring physical therapy assistants in South Carolina include ATI Physical Therapy, McLeod Health, and The Weston, per current listings on Migrate Mate as of August 2026. South Carolina's large health systems and post-acute care networks consistently post PTA openings across the state's major metropolitan and rural service areas.
Which South Carolina cities have the most physical therapy assistant jobs?
Greenville, Columbia, and Aiken have the most physical therapy assistant openings in South Carolina. Columbia leads as the state capital with a high concentration of hospital systems and outpatient clinics, while Greenville's growing Upstate health corridor and Charleston's strong medical and retirement community base drive consistent demand in those metros.
Are there remote physical therapy assistant jobs in South Carolina?
Yes, but they're rare. Physical therapy assistant work is hands-on by nature, requiring direct patient contact for exercises, manual techniques, and functional assessments. About 0% of physical therapy assistant openings tied to South Carolina are remote or hybrid as of August 2026, and those positions are almost exclusively limited to documentation review, telehealth care coordination, or administrative support roles within larger rehabilitation organizations.
How can I get hired as a physical therapy assistant in South Carolina with little or no experience?
The most realistic entry path is applying to new-graduate positions at large South Carolina health systems like Prisma Health or MUSC Health, which regularly hire recent PTA graduates into supervised clinical roles. Candidates who worked as rehab aides or physical therapy technicians during school hold a real advantage, since that hands-on background translates directly. Completing your South Carolina licensure promptly after graduation and targeting skilled nursing facilities or outpatient orthopedic clinics, which tend to onboard new PTAs more readily than acute hospital settings, will strengthen your candidacy.
Where can I find and apply to physical therapy assistant jobs in South Carolina?
You can find and apply to physical therapy assistant jobs in South Carolina on Migrate Mate, which lists current openings across the state. Search the listings to find roles that fit your experience level, specialty, and preferred location, then apply directly to the ones that match.
See All 79 Physical Therapy Assistant Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
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