Nurse Resident Jobs in South Carolina

Nurse Resident jobs in South Carolina are consistently active, with strong demand driven by hospital systems, academic medical centers, and growing suburban health networks across the state. Most hiring concentrates in Columbia, Charleston, and Greenville, where large employers such as MUSC Health, Prisma Health, and Bon Secours have deep-rooted residency programs. Critical care, medical-surgical, and emergency nursing are the specialties where new-graduate nurse residents are placed most often. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles42
Top employerPrisma Health
Top cityColumbia, SC
Cities hiring9
Work type100% On-site
Top industryHealthcare

Showing 5 of 42+ Nurse Resident jobs

Licensed Practical Nurse (LPN) - Nurse Resident, December 2026, Surgical Specialty
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Licensed Practical Nurse (LPN) - Nurse Resident, December 2026, Surgical Specialty
Prisma Health
Seneca, South Carolina
Business Development
Customer Success
Program Management
Project Management
10,000+

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Licensed Practical Nurse (LPN) – Nurse Resident, December 2026, Medical Telemetry
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Licensed Practical Nurse (LPN) – Nurse Resident, December 2026, Medical Telemetry
Prisma Health
Greer, South Carolina
Business Development
Customer Success
Program Management
Project Management
10,000+

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Registered Nurse (RN) – Nurse Resident, December 2026, Medical/Surgical Unit
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Registered Nurse (RN) – Nurse Resident, December 2026, Medical/Surgical Unit
Prisma Health
Seneca, South Carolina
Customer Service
Customer Support
Hospitality & Guest Services
Bachelor of Science in Nursing
10,000+

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Registered Nurse (RN) - Nurse Resident, December 2026, Hartwell Suite, Cardiovascular Stepdown/LVAD
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Registered Nurse (RN) - Nurse Resident, December 2026, Hartwell Suite, Cardiovascular Stepdown/LVAD
Prisma Health
Columbia, South Carolina
Healthcare Administration
Patient Services & Wellbeing
Social Work & Counseling
Bachelor of Science in Nursing
10,000+

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Registered Nurse (RN)- Nurse Resident, December 2026, Emergency Department
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Added 2mo ago
Registered Nurse (RN)- Nurse Resident, December 2026, Emergency Department
Prisma Health
Columbia, South Carolina
Customer Service
Customer Support
Hospitality & Guest Services
Bachelor of Science in Nursing
10,000+

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Nurse Resident Jobs by City in South Carolina

Where South Carolina roles are concentrated, by current openings.

Seneca
5 jobs
Sumter
5 jobs
Greenville
5 jobs
Greer
4 jobs
Easley
2 jobs
Clinton
2 jobs
Simpsonville
1 job
Travelers Rest
1 job

Nurse Resident Job Market in South Carolina

A snapshot from current South Carolina openings, updated as new roles post.

Who's Hiring

Prisma Health42 open roles

Top Industries Hiring

  • Healthcare & Medical Services

What South Carolina Employers Look For

The qualifications that appear most often in nurse resident jobs across South Carolina.

  • Active South Carolina RN license or eligibility through the Nurse Licensure Compact
  • Completion of an accredited associate or bachelor of science in nursing program
  • Passing score on the NCLEX-RN examination before or within residency onboarding
  • Basic Life Support certification from an approved provider prior to start date
  • Commitment to a structured residency program typically lasting twelve months
  • Strong clinical reasoning skills demonstrated through nursing school clinical rotations

Nurse Resident Jobs in South Carolina: Frequently Asked Questions

How do you become a nurse resident in South Carolina?

To become a nurse resident in South Carolina, you must first earn an accredited associate or bachelor of science in nursing degree, then pass the NCLEX-RN and apply for licensure through the South Carolina Board of Nursing. South Carolina participates in the Nurse Licensure Compact, so nurses already licensed in another compact state can work without a separate application. Once licensed, you apply directly to nurse residency programs at hospital systems such as MUSC Health or Prisma Health, which accept new graduates through structured cohort intakes.

Which companies hire nurse residents in South Carolina?

Companies currently hiring nurse residents in South Carolina include Prisma Health, per current listings on Migrate Mate as of October 2026. South Carolina's large integrated health systems, particularly those with teaching hospital affiliations in Columbia and Charleston, post the greatest volume of nurse residency openings throughout the year.

Which South Carolina cities have the most nurse resident jobs?

Columbia, Seneca, and Sumter account for the largest share of nurse resident openings in South Carolina. Columbia leads because of its concentration of state government employees, university medical affiliates, and Prisma Health's flagship facilities, while Charleston's volume is driven by MUSC Health's academic medical campus, and Greenville reflects Bon Secours' expanding regional network in the Upstate.

Are there remote nurse resident jobs in South Carolina?

Yes, but they're rare. Nurse residency roles are fundamentally hands-on positions requiring in-person patient care, so the vast majority require on-site work. About 0% of nurse resident openings tied to South Carolina are remote or hybrid as of October 2026, and those exceptions typically cover care coordination, telephonic triage, or population health components embedded within a residency track rather than fully bedside-free positions.

How can I get hired as a nurse resident in South Carolina with little or no experience?

The most realistic entry path is applying directly to a formal nurse residency program, which is specifically designed for candidates with no post-graduation experience. MUSC Health, Prisma Health, and Bon Secours all run structured new-graduate residency cohorts in South Carolina that provide supervised clinical mentorship for the first year. Candidates who complete clinical rotations at these systems during nursing school have a practical advantage when applying. Holding a current South Carolina RN license or compact equivalency and an ACLS certification alongside BLS strengthens any application before the cohort selection process.

Where can I find and apply to nurse resident jobs in South Carolina?

You can find and apply to nurse resident jobs in South Carolina on Migrate Mate, which lists current openings from employers actively hiring in the state. Search the available roles, identify the ones that match your credentials and preferred location, and apply directly to the ones that fit.

See All 42 Nurse Resident Jobs in South Carolina

Find roles in South Carolina that match your experience and apply in just a few clicks.

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