Clinic Registered Nurse Jobs in South Carolina
Clinic Registered Nurse jobs in South Carolina draw consistent demand across outpatient clinics, physician group practices, and federally qualified health centers, with openings available from new graduate to experienced specialty nurse. Columbia, Greenville, and Charleston anchor the largest share of hiring, where major systems such as Prisma Health, MUSC Health, and Bon Secours St. Francis regularly staff clinic RN roles. Ambulatory care, primary care, and chronic disease management are the most active specialties in the state right now. Scan the live roles below and apply to whichever ones fit.
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We are seeking a Clinical Coordinator to assist with all clinical needs for our Murrells Inlet patients. The Clinical Coordinator plays a crucial role ensuing the seamless coordinator of patient care. This position involves proficient chart preparation, communication, scheduling of patient visits, appropriate utilization and logging of chronic care management activities, and provider and patient support.
This position will be working in the Murrells Inlet clinic daily. This is a full-time, salary-based 8-hr position (8:00AM-5:00PM) (Monday-Friday).
About
We are a leading physician group serving South Carolina and Georgia, dedicated to delivering quality healthcare directly to patients in care facilities, homes, clinics, and virtual visits. Our services include comprehensive primary care, specialty services, and pharmacy support, tailored to meet diverse patient needs. Committed to excellence and innovation, our team collaborates closely with facilities and families to ensure accessible, coordinated, and compassionate care.
Why Choose a Career at Your Health?
Providing high quality care for our patients is the center of what we do, and we provide the same care for our employees. Here are some of the benefits that are available to our employees.
- Competitive Compensation Package with Bonus Opportunities
- Employer Matched 401K
- Free Visit & Prescriptive Services with HDHP Insurance Plan
- Employer Matched HSA
- Generous PTO Package
- Career Development & Growth Opportunities
What Are We Looking For?
Your Health is currently looking for a Clinical Coordinator to join our growing primary care family. A successful Clinical Coordinator will be able to perform these essential duties and responsibilities accurately and efficiently. Prior experience in a similar role is crucial to the success of our team due to the fast past and value-based model of care.
The following is a list of essential functions, which may be subject to change at any time and without
notice. Management may assign new duties, reassign existing duties, and/or eliminate function(s).
Areas of Responsibility:
- Review and organize patient medical records in preparation for visits.
- Ensure all necessary documentation, test results, documents, diagnoses, and relevant information are accessible for the provider. Utilize Navina to ensure these are added, completed, and/or updated.
- Maintain accurate up-to-date patient records, including demographic information, contact details, insurance information, appointment history, etc.
- Ensure confidentiality and adhere to privacy regulations when handling sensitive patient information. Verify active consent forms and alignment paperwork are completed and in the patient’s chart.
- Reconcile medications.
- Collaborate with care team to schedule and coordinator patient appointments with the Company’s provider(s), and other members of the care team
- Interact with patients via email, patient portal, telephone, text, in-person, etc. to gather necessary information, schedule and confirm appointments in advance, and provide pre-appointment instructions.
- Communication methods such as phone, email, AthenaText, Microsoft Teams, etc. will be utilized.
- Appropriately and accurately document and log care management activities.
Qualifications
- Must be a Certified Medical Assistant (CMA) or licensed nurse (i.e. LPN or RN). Must be licensed in the state of employment. Certification/license must be in good standing with the appropriate board.
- A minimum of one (1) year experience in a healthcare setting preferred.
- Must hold and maintain current CPR certificate.
- High school diploma or equivalent required.
- Should demonstrate strong interpersonal and communication skills under all conditions and circumstances.
- Ability to foster a cooperative work environment.
- Team player with ability to manage multiple responsibilities and demonstrate sound judgment.
- Ability to read and communicate effectively.
- Strong written and verbal communication skills.
- Basic computer knowledge.
- Must be able to work flexible hours and travel between offices, facilities, etc.
- Must be a licensed driver with an automobile that is insured in accordance with state and/or organization requirements and is in good working condition.
See All 9 Clinic Registered Nurse Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find Clinic Registered Nurse JobsClinic Registered Nurse Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Clinic Registered Nurse Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Healthcare & Medical Services
What South Carolina Employers Look For
The qualifications that appear most often in clinic registered nurse jobs across South Carolina.
- Active Registered Nurse license issued or recognized by the South Carolina Board of Nursing
- Associate or Bachelor of Science in Nursing degree from an accredited program
- Current BLS certification and CPR card from an accredited provider
- Minimum one year of clinical nursing experience in an ambulatory or outpatient setting
- Proficiency with electronic health record systems such as Epic or Cerner
- Strong patient triage and care coordination skills in a high-volume clinic environment
Clinic Registered Nurse Jobs in South Carolina: Frequently Asked Questions
How do you become a clinic registered nurse in South Carolina?
You become a clinic registered nurse in South Carolina by earning an Associate Degree in Nursing or a Bachelor of Science in Nursing from an accredited program, passing the NCLEX-RN exam, and obtaining licensure through the South Carolina Board of Nursing. South Carolina participates in the Nurse Licensure Compact, so nurses licensed in other compact states may practice here without a separate state license, though you must verify your license status with the Board directly.
How much do clinic registered nurses make in South Carolina?
Clinic registered nurses in South Carolina earn a median of about $82,360 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $66,860 for the lowest 10% to over $106,520 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire clinic registered nurses in South Carolina?
Companies currently hiring clinic registered nurses in South Carolina include Prisma Health, Your Health Organization, and Atrium Health, per current listings on Migrate Mate as of October 2026. South Carolina's major integrated health systems and federally qualified health centers generate the most consistent clinic RN openings, particularly in the Midlands and Upstate regions.
Which South Carolina cities have the most clinic registered nurse jobs?
Rock Hill, Greenville, and Aiken County have the most clinic registered nurse openings in South Carolina. Columbia leads as the state capital and home to the largest Prisma Health campus, while Greenville's rapid population growth and MUSC Health's Upstate expansion drive strong demand there, and Charleston's concentration of academic medical and specialty outpatient centers sustains steady hiring.
Are there remote clinic registered nurse jobs in South Carolina?
Yes, but they're rare. About 100% of clinic registered nurse openings tied to South Carolina are remote or hybrid as of October 2026, reflecting the hands-on patient care nature of most clinic RN roles. The positions most likely to include a remote component are telephone triage, chronic care management, and nurse advice line roles that do not require an in-person clinical setting.
How can I get hired as a clinic registered nurse in South Carolina with little or no experience?
The most realistic entry path is a new graduate or nurse residency program offered by large South Carolina health systems such as Prisma Health or MUSC Health, which provide structured clinical orientation for RNs with limited post-graduation experience. Entry-level clinic roles in school health services, public health departments, and federally qualified health centers across the state also regularly hire new graduates. Holding an active South Carolina Board of Nursing license, BLS certification, and any ambulatory clinical hours from nursing school practicum rotations strengthens a first application considerably.
Where can I find and apply to clinic registered nurse jobs in South Carolina?
You can find and apply to clinic registered nurse jobs in South Carolina on Migrate Mate, which lists current South Carolina openings in one place. Search through the roles available, find the ones that match your experience and preferred location, and apply directly to the ones that fit.
See All 9 Clinic Registered Nurse Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
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