Clinic Registered Nurse Jobs in South Carolina
Clinic Registered Nurse jobs in South Carolina are open across Spartanburg, Charleston, and Conway and other South Carolina metros, with employers like Dialysis Clinic, Medical University of South Carolina, and Prisma Health hiring at every experience level. Find a role that fits below and apply directly.
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INTRODUCTION
MUSC Community Physicians (MCP) is an entity within the Medical University of South Carolina that provides healthcare to patients within the rural health network throughout the state of South Carolina.
ROLE AND RESPONSIBILITIES
The Clinic Lead Nurse reports to the Office Manager and, under general supervision, provides individualized, goal-directed patient care to employees, dependents, and retirees served by the Horry County Employee Health & Wellness Center. Utilizing the principles and practices of the nursing process, the Clinic Lead Nurse II delivers safe, effective, and evidence-based care while collaborating with providers, clinical staff, occupational health personnel, and other members of the healthcare team to achieve desired patient outcomes.
The Clinic Lead Nurse works in coordination with the Office Manager, Medical Director, and nursing leadership to support efficient daily operations, regulatory compliance, patient safety, and service excellence. This position assists in ensuring the achievement of departmental goals through operational oversight, workflow coordination, quality improvement activities, and support of clinical staff. The Clinic Lead Nurse II serves as a clinical resource and leadership presence within the clinic while supporting primary care, preventive care, wellness services, care coordination, employee health, and occupational health programs provided to county employees, dependents, and retirees.
This position plays a key role in supporting employer-sponsored health initiatives, workforce wellness programs, occupational health services, employee onboarding activities, and community partnerships that advance the health and well-being of the Horry County workforce.
Some Responsibilities Includes but not limited to:
- Serves as a leadership presence within the clinic and provides support, guidance, and mentorship to nursing and clinical support staff.
- Functions as a clinical resource for staff regarding nursing practice, patient care standards, occupational health protocols, and clinic workflows.
- Collaborates with providers, the Office Manager, and operational leadership to identify and implement workflow improvements that enhance patient access, efficiency, and service delivery.
- Coordinates daily staffing assignments and clinical workflows as delegated by the Office Manager to ensure operational needs are met.
- Provides patient care, insuring prompt response to patient in basket messages, coordinating follow-up cares and ensuring prompt referrals for patient population.
- Promotes a culture of teamwork, accountability, service excellence, and patient-centered care.
- Provides direct nursing care utilizing the nursing process and evidence-based practice standards.
- Performs nursing assessments, patient triage, medication reconciliation, and clinical documentation.
- Coordinates referrals to specialty care, diagnostic services, physical therapy, behavioral health, occupational medicine, and ancillary services.
- Manages referral tracking processes to ensure patients receive timely access to recommended care and follow-up.
- Supports occupational medicine programs and workplace health initiatives for county employees.
- Assists with pre-employment evaluations, annual occupational surveillance examinations, return-to-work evaluations, and fitness-for-duty assessments.
- Performs audiometric testing, hearing conservation screenings, spirometry testing, vision screening, and other occupational health assessments as required.
- Ensures compliance with MUSC Health policies and procedures, HIPAA requirements, OSHA standards, CLIA regulations, infection prevention guidelines, and applicable regulatory agencies.
- Participates in quality improvement initiatives, chart audits, patient safety activities, and performance monitoring programs.
- Promotes a culture of exceptional customer service and patient-centered care.
- Addresses patient concerns and service recovery opportunities in a timely and professional manner.
- Supports employee wellness initiatives, health education programs, and preventive health activities.
MINIMUM QUALIFICATIONS
Associate Degree in Nursing and a minimum of two (2) years of work experience as a Registered Nurse required. Bachelor of Science in Nursing (BSN) preferred.
Previous ambulatory care experience preferred. Experience in primary care, employee health, occupational health, employer-sponsored health clinics, or care coordination strongly preferred.
RN staff hired on or after July 1, 2013, with an Associate Degree or Diploma in Nursing are required to be enrolled in an accredited BSN program within two years and successfully obtain a BSN degree within four years of the RN hire or reclassification date in accordance with MUSC Health Policy A141.
REQUIRED LICENSURE, CERTIFICATIONS, AND REGISTRATIONS
- Current South Carolina licensure as a Registered Nurse or compact state licensure required.
- Current Basic Life Support (BLS) certification required, either a certification from an American Heart Association (AHA) BLS for Healthcare Providers (or AHA-recognized equivalent) or an American Red Cross CPR/AED for Professional Rescuer and Healthcare Provider.
- ACLS certification if required by clinic operations.
- Obtain DOT/BAT certification within six months and OHN certification within one year are required.
BENEFITS
- Health, dental, vision, and life insurance
- Employer Sponsored Retirement Plan
- Paid time off and extended sick leave
- Paid Parental Leave
- Disability insurance plan options
- Continuous professional and clinical training
- Competitive pay
- Annual Merit Increase
- Wellbeing resources
- Tuition Reimbursement
- Employee perks and discounts
- Employee referral program
- Flexible schedule options
Certification incentive program
If you like working with energetic enthusiastic individuals, you will enjoy your career with us!
The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need.
Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: http://www.uscis.gov/e-verify/employees
LOCATION
Location: Conway, South Carolina
WORKER TYPE
Worker Type: Employee
WORKER SUB-TYPE
Worker Sub-Type: Regular
COST CENTER
Cost Center: CC006012 MCP - Occupational Health Horry County Employee Wellness
PAY RATE TYPE
Pay Rate Type: Salary
PAY GRADE
Pay Grade: Health-30
SCHEDULED WEEKLY HOURS
Scheduled Weekly Hours: 40
WORK SHIFT
Work Shift:
See All 17 Clinic Registered Nurse Jobs in South Carolina
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Find Clinic Registered Nurse JobsClinic Registered Nurse Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Clinic Registered Nurse Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring
- Dialysis Clinic14

- Medical University of South Carolina2

- Prisma Health1

Top Industries Hiring
- Healthcare & Medical Services16
- Education1
What South Carolina Employers Look For
The qualifications that appear most often in clinic registered nurse jobs across South Carolina.
- Active RN license in the state of employment or a compact multistate license
- Current BLS certification required at time of hire
- One or more years of outpatient, clinic, or ambulatory care nursing experience
- Proficiency with electronic health record systems such as Epic, Athenahealth, or Cerner
- Associate degree in Nursing required, Bachelor of Science in Nursing preferred by most employers
- Strong patient education, triage, and care coordination skills in a high-volume setting
Clinic Registered Nurse Jobs in South Carolina: Frequently Asked Questions
How many clinic registered nurse jobs are there in South Carolina?
There are 17+ clinic registered nurse openings in South Carolina on Migrate Mate as of June 2026, with the most roles in Spartanburg, Charleston, and Conway. New positions post regularly as employers across South Carolina hire.
How much do clinic registered nurses make in South Carolina?
Clinic registered nurses in South Carolina earn a median of about $82,360 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $66,860 for the lowest 10% to over $106,520 for the top 10%. Pay rises with experience, specialty, and employer.
Which South Carolina cities have the most clinic registered nurse jobs?
Spartanburg, Charleston, and Conway have the most clinic registered nurse openings in South Carolina right now, with additional roles spread across smaller metros statewide.
Which companies hire clinic registered nurses in South Carolina?
Employers hiring clinic registered nurses in South Carolina include Dialysis Clinic, Medical University of South Carolina, and Prisma Health, based on current listings on Migrate Mate as of June 2026.
Are there remote clinic registered nurse jobs in South Carolina?
Yes. About 0% of clinic registered nurse openings tied to South Carolina are remote or hybrid as of June 2026. The rest are on-site roles based in South Carolina metros.
How do I apply for clinic registered nurse jobs in South Carolina?
You can apply to clinic registered nurse jobs in South Carolina directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred South Carolina location, then apply to each one that fits.
See All 17 Clinic Registered Nurse Jobs in South Carolina
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