Home Health Nurse Jobs in South Carolina

Home Health Nurse jobs in South Carolina are in strong and steady demand, concentrated in pediatric, geriatric, and post-acute care as the state's aging rural and suburban populations require more in-home clinical support. The largest hiring markets are Columbia, Greenville, and Charleston, where established employers like Amedisys, LHC Group, and Prisma Health maintain active home health divisions. Openings range from entry-level visiting nurse positions through senior case manager and specialty infusion roles. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles113+
Top employerAmedisys
Top cityColumbia, SC
Cities hiring48
Work type100% On-site
Top industryHealthcare

Showing 5 of 113+ Home Health Nurse jobs

Spartanburg Regional Healthcare System
Registered Nurse (RN) - Home Health
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Spartanburg Regional Healthcare System
Added 1d ago
Registered Nurse (RN) - Home Health
Spartanburg Regional Healthcare System
Spartanburg, South Carolina
Healthcare Administration
Patient Services & Wellbeing
Social Work & Counseling
CPR Certification

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Angels of Care Pediatric Home Health
Licensed Practical Nurse (LPN) / Registered Nurse (RN) – Pediatric Home Health
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Angels of Care Pediatric Home Health
Added 1d ago
Licensed Practical Nurse (LPN) / Registered Nurse (RN) – Pediatric Home Health
Angels of Care Pediatric Home Health
Summerville, South Carolina
Healthcare Administration
Nursing
Patient Services & Wellbeing
1,001-5,000

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PruittHealth
Registered Nurse RN Home Health
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PruittHealth
Added 1d ago
Registered Nurse RN Home Health
PruittHealth
Rock Hill, South Carolina
Program Management
Project Management
Quality Assurance & Testing (QA Testing)
CPR Certification
10,000+

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Amedisys
LPN Licensed Practical Nurse Home Health
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Amedisys
Added 1d ago
LPN Licensed Practical Nurse Home Health
Amedisys
Conway, South Carolina
Healthcare Administration
Nursing
Patient Services & Wellbeing
$28 - $33/hr
CPR Certification
10,000+

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CenterWell
Home Health Licensed Practical Nurse
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CenterWell
Added 1d ago
Home Health Licensed Practical Nurse
CenterWell
Florence, South Carolina
Customer Service
Customer Support
Hospitality & Guest Services
$53k - $73k/yr
CPR Certification
1,001-5,000

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Home Health Nurse Jobs by City in South Carolina

Where South Carolina roles are concentrated, by current openings.

Columbia
10 jobs
Rock Hill
7 jobs
Myrtle Beach
7 jobs
Aiken
6 jobs
Ladson
5 jobs
Bluffton
5 jobs
Florence
5 jobs
Greenville
5 jobs
Simpsonville
5 jobs

Home Health Nurse Job Market in South Carolina

A snapshot from current South Carolina openings, updated as new roles post.

Who's Hiring

  • Amedisys
    Amedisys18
  • CenterWell
    CenterWell17
  • PruittHealth
    PruittHealth11
  • Professional Case Management
    Professional Case Management10
  • BAYADA Home Health Care
    BAYADA Home Health Care8

Top Industries Hiring

  • Healthcare & Medical Services

What South Carolina Employers Look For

The qualifications that appear most often in home health nurse jobs across South Carolina.

  • Active Registered Nurse license issued or recognized by the South Carolina Board of Nursing
  • Current CPR and Basic Life Support certification required for all patient-facing assignments
  • Minimum one year of clinical nursing experience in a medical-surgical or post-acute setting
  • Valid driver's license and reliable personal vehicle for patient home visits
  • Proficiency with electronic health record systems such as Homecare Homebase or Epic
  • Demonstrated ability to work autonomously and manage a patient caseload independently

Home Health Nurse Jobs in South Carolina: Frequently Asked Questions

How do you become a home health nurse in South Carolina?

To become a home health nurse in South Carolina, you must first hold an active Registered Nurse license issued by the South Carolina Board of Nursing, which requires completing an accredited nursing program and passing the NCLEX-RN exam. Once licensed, most home health employers expect at least one year of clinical experience in a hospital or post-acute setting before placing nurses in independent home visit roles. A valid driver's license is also required.

How much do home health nurses make in South Carolina?

Home health nurses in South Carolina earn a median of about $82,360 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $66,860 for the lowest 10% to over $106,520 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire home health nurses in South Carolina?

Companies currently hiring home health nurses in South Carolina include Amedisys, CenterWell, and PruittHealth, per current listings on Migrate Mate as of August 2026. South Carolina's mix of large regional health systems and national home health chains means openings are distributed across urban centers like Columbia and Greenville as well as underserved rural counties.

Which South Carolina cities have the most home health nurse jobs?

Columbia, Rock Hill, and Myrtle Beach account for the highest concentration of home health nurse openings in South Carolina. Columbia's role as the state capital anchors large health systems and state-administered home care programs, while Greenville's expanding medical corridor and Charleston's growing retiree population drive consistent demand in those metros.

Are there remote home health nurse jobs in South Carolina?

Yes, but they're rare. About 0% of home health nurse openings tied to South Carolina are remote or hybrid as of August 2026, reflecting the hands-on nature of bedside and home visit care. The roles most likely to include a remote component are telephonic case management, care coordination, and utilization review positions attached to home health agencies.

How can I get hired as a home health nurse in South Carolina with little or no experience?

The most realistic entry path is completing a new graduate residency or clinical transition program at a South Carolina health system such as Prisma Health or MUSC, which place new nurses in supervised home health rotations. From there, lateral moves from med-surg, rehabilitation, or long-term care units into home health are common. Holding a current South Carolina Board of Nursing RN license and a home health aide or case management certificate strengthens an entry-level application considerably.

Where can I find and apply to home health nurse jobs in South Carolina?

You can find and apply to home health nurse jobs in South Carolina on Migrate Mate, which lists current openings across the state. Search the listings, identify the roles that match your credentials and preferred location, and apply directly to whichever ones fit your situation.

See All 113+ Home Health Nurse Jobs in South Carolina

Find roles in South Carolina that match your experience and apply in just a few clicks.

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