Home Health Nurse Jobs in South Carolina
Home Health Nurse jobs in South Carolina are in strong and steady demand, concentrated in pediatric, geriatric, and post-acute care as the state's aging rural and suburban populations require more in-home clinical support. The largest hiring markets are Columbia, Greenville, and Charleston, where established employers like Amedisys, LHC Group, and Prisma Health maintain active home health divisions. Openings range from entry-level visiting nurse positions through senior case manager and specialty infusion roles. Scan the live roles below and apply to whichever ones fit.
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SIGN ON BONUS $10,000.00 Eligible Experienced RN
We are hiring a Registered Nurse to join our Home Health team!
- Full-Time; 8:30 am- 5:00 pm
We are proud of our skilled, caring, trustworthy and compassionate Home Health experts. Our clinicians visit patient homes to deliver customized, physician-prescribed care after a hospital stay, illness or injury to rehabilitate and achieve optimal level of independence. Home Health is an alternative to repeated hospitalizations or an extended hospital stay. Nurses and medical professionals work closely with primary care physicians and ensure patients are receiving optimum care tailored to individual needs.
Our Registered Nurses enjoy autonomy while caring for patients in their home environment. The team works with a wide variety of cases such as: Wound Care, Cardiac, Diabetes, Endocrine, Musculosketal, Pressure Ulcers, Infusion, etc. The average length of patient care is 47 days.
The Registered Nurse provides skilled nursing services within the home care setting in accordance with the orders of a physician and under a plan of care. Through use of the nursing process, utilizes knowledge and skills at a competent level to provide direct age-specific and culturally appropriate patient care management in the homecare setting. The RN also serves as a clinical resource, participates in patient and staff education, demonstrates the use of independent nursing judgment, and serves as a preceptor. Develops and coordinates the plan of care and provides case management. Performs other duties as assigned.
Minimum Requirements
Education
- Graduate of an approved nursing program
Experience
- One (1) year of recent clinical nursing experience
License/Registration/Certifications
- Current license to practice as a Registered Nurse in South Carolina
- Valid SC driver's license with good driving record
- CPR certification
Core Job Responsibilities
- Responsible for continuous review of all aspects of patients on his/her caseload to include but not limited to: appropriate utilization of services; review of documentation in the medical record; maintenance of interdisciplinary communication and discharge planning.
- Completes an initial assessment of patient and family to determine home care needs. Provides a complete physical assessment and history of current and previous illness(es) and medication reconciliation.
- Collaborates with patients, families, and other members of the interdisciplinary care team to establish appropriate treatment plan and develop a plan of care.
- Initiates the plan of care, makes necessary revisions as patient status, and needs change. Regularly re-evaluates patient nursing needs.
- Initiates and facilitates interdisciplinary collaboration to enhance outcomes.
- Initiates appropriate nursing interventions. Provides treatments as prescribed by the physician.
- Provides health care instructions to the patient as appropriate per assessment and plan. Educates the patient and family/caregiver on self-care techniques medications, diet and other instructions as ordered.
- Recognizes and utilizes opportunities for health counseling with patients and families/ caregivers.
- Communicates with the physician regarding the patient's needs and reports changes in the patient's condition; communicates regularly with the interdisciplinary team; communicates with community health related persons to coordinate the plan of care; and communicates on a regular basis with manager.
- Provides supervision of home health aides per regulatory requirements.
- Complies with established policies and procedures.
- Knowledge of and compliance with state, federal, and local regulations for the delivery of home care services.
- Performs other duties as assigned.
See All 113+ Home Health Nurse Jobs in South Carolina
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Find Home Health Nurse JobsHome Health Nurse Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Home Health Nurse Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring
- Amedisys18

- CenterWell17

- PruittHealth11

- Professional Case Management10

- BAYADA Home Health Care8

Top Industries Hiring
- Healthcare & Medical Services
What South Carolina Employers Look For
The qualifications that appear most often in home health nurse jobs across South Carolina.
- Active Registered Nurse license issued or recognized by the South Carolina Board of Nursing
- Current CPR and Basic Life Support certification required for all patient-facing assignments
- Minimum one year of clinical nursing experience in a medical-surgical or post-acute setting
- Valid driver's license and reliable personal vehicle for patient home visits
- Proficiency with electronic health record systems such as Homecare Homebase or Epic
- Demonstrated ability to work autonomously and manage a patient caseload independently
Home Health Nurse Jobs in South Carolina: Frequently Asked Questions
How do you become a home health nurse in South Carolina?
To become a home health nurse in South Carolina, you must first hold an active Registered Nurse license issued by the South Carolina Board of Nursing, which requires completing an accredited nursing program and passing the NCLEX-RN exam. Once licensed, most home health employers expect at least one year of clinical experience in a hospital or post-acute setting before placing nurses in independent home visit roles. A valid driver's license is also required.
How much do home health nurses make in South Carolina?
Home health nurses in South Carolina earn a median of about $82,360 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $66,860 for the lowest 10% to over $106,520 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire home health nurses in South Carolina?
Companies currently hiring home health nurses in South Carolina include Amedisys, CenterWell, and PruittHealth, per current listings on Migrate Mate as of August 2026. South Carolina's mix of large regional health systems and national home health chains means openings are distributed across urban centers like Columbia and Greenville as well as underserved rural counties.
Which South Carolina cities have the most home health nurse jobs?
Columbia, Rock Hill, and Myrtle Beach account for the highest concentration of home health nurse openings in South Carolina. Columbia's role as the state capital anchors large health systems and state-administered home care programs, while Greenville's expanding medical corridor and Charleston's growing retiree population drive consistent demand in those metros.
Are there remote home health nurse jobs in South Carolina?
Yes, but they're rare. About 0% of home health nurse openings tied to South Carolina are remote or hybrid as of August 2026, reflecting the hands-on nature of bedside and home visit care. The roles most likely to include a remote component are telephonic case management, care coordination, and utilization review positions attached to home health agencies.
How can I get hired as a home health nurse in South Carolina with little or no experience?
The most realistic entry path is completing a new graduate residency or clinical transition program at a South Carolina health system such as Prisma Health or MUSC, which place new nurses in supervised home health rotations. From there, lateral moves from med-surg, rehabilitation, or long-term care units into home health are common. Holding a current South Carolina Board of Nursing RN license and a home health aide or case management certificate strengthens an entry-level application considerably.
Where can I find and apply to home health nurse jobs in South Carolina?
You can find and apply to home health nurse jobs in South Carolina on Migrate Mate, which lists current openings across the state. Search the listings, identify the roles that match your credentials and preferred location, and apply directly to whichever ones fit your situation.
See All 113+ Home Health Nurse Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
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