Home Health Nurse Jobs in South Carolina
Home Health Nurse jobs in South Carolina are in strong and steady demand, concentrated in pediatric, geriatric, and post-acute care as the state's aging rural and suburban populations require more in-home clinical support. The largest hiring markets are Columbia, Greenville, and Charleston, where established employers like Amedisys, LHC Group, and Prisma Health maintain active home health divisions. Openings range from entry-level visiting nurse positions through senior case manager and specialty infusion roles. Scan the live roles below and apply to whichever ones fit.
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Showing 5 of 122+ Home Health Nurse jobs
- $32.05-$40.06
- Choice of PPO or HSA medical plans with free telehealth.
- Paid time off.
- Up to $1,000 in free healthcare services with Amedisys HSA plan.
- Up to $500 in wellness rewards for activities-use for spa, gym, sports, hobbies, pets and more.*
- Mental health support with up to five free counseling sessions through the Employee Assistance program.
- 401(k) with a company match.
- Family support with infertility treatment coverage*, adoption reimbursement, paid parental and family caregiver leave.
- Fleet vehicle program (restrictions apply) and mileage reimbursement.
- And more.
- Benefit eligibility can vary by position and shift status.
- Participation requires enrollment in an Amedisys medical plan.
- Verify plan of care with the RN prior to each visit.
- Collaborate with physician and RN frequently to ensure patient needs are being met; Notify them as soon as possible when patient condition changes.
- Teach patients and caregivers self-care techniques.
- Check vital signs.
- Review all medications and perform a medication reconciliation at each visit.
- Perform specialized procedures ordered by physician (i.e. foley catheter change).
- Prepare equipment and materials for treatments using the aseptic technique.
- Complete documentation timely and accurately.
- One year of clinical LPN experience.
- Current LPN license, specific to the state(s) you are assigned to work.
- Current CPR certification.
- Valid driver's license, reliable transportation and liability insurance.
Amedisys is an equal opportunity employer. All qualified employees and applicants will receive consideration for employment without regard to race, color, religion, sex, age, pregnancy, marital status, national origin, citizenship status, disability, military status, sexual orientation, genetic predisposition or carrier status or any other legally protected characteristic.
- $32.05-$40.06
- Choice of PPO or HSA medical plans with free telehealth.
- Paid time off.
- Up to $1,000 in free healthcare services with Amedisys HSA plan.
- Up to $500 in wellness rewards for activities-use for spa, gym, sports, hobbies, pets and more.*
- Mental health support with up to five free counseling sessions through the Employee Assistance program.
- 401(k) with a company match.
- Family support with infertility treatment coverage*, adoption reimbursement, paid parental and family caregiver leave.
- Fleet vehicle program (restrictions apply) and mileage reimbursement.
- And more.
- Benefit eligibility can vary by position and shift status.
- Participation requires enrollment in an Amedisys medical plan.
- Verify plan of care with the RN prior to each visit.
- Collaborate with physician and RN frequently to ensure patient needs are being met; Notify them as soon as possible when patient condition changes.
- Teach patients and caregivers self-care techniques.
- Check vital signs.
- Review all medications and perform a medication reconciliation at each visit.
- Perform specialized procedures ordered by physician (i.e. foley catheter change).
- Prepare equipment and materials for treatments using the aseptic technique.
- Complete documentation timely and accurately.
- One year of clinical LPN experience.
- Current LPN license, specific to the state(s) you are assigned to work.
- Current CPR certification.
- Valid driver's license, reliable transportation and liability insurance.
Amedisys is an equal opportunity employer. All qualified employees and applicants will receive consideration for employment without regard to race, color, religion, sex, age, pregnancy, marital status, national origin, citizenship status, disability, military status, sexual orientation, genetic predisposition or carrier status or any other legally protected characteristic.
See All 122+ Home Health Nurse Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find Home Health Nurse JobsHome Health Nurse Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Home Health Nurse Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring
- Amedisys17
- CenterWell16
- Matrix Medical Network13
- Professional Case Management13
- Medical Services of America12
Top Industries Hiring
- Healthcare & Medical Services
- Insurance
What South Carolina Employers Look For
The qualifications that appear most often in home health nurse jobs across South Carolina.
- Active Registered Nurse license issued or recognized by the South Carolina Board of Nursing
- Current CPR and Basic Life Support certification required for all patient-facing assignments
- Minimum one year of clinical nursing experience in a medical-surgical or post-acute setting
- Valid driver's license and reliable personal vehicle for patient home visits
- Proficiency with electronic health record systems such as Homecare Homebase or Epic
- Demonstrated ability to work autonomously and manage a patient caseload independently
Home Health Nurse Jobs in South Carolina: Frequently Asked Questions
How do you become a home health nurse in South Carolina?
To become a home health nurse in South Carolina, you must first hold an active Registered Nurse license issued by the South Carolina Board of Nursing, which requires completing an accredited nursing program and passing the NCLEX-RN exam. Once licensed, most home health employers expect at least one year of clinical experience in a hospital or post-acute setting before placing nurses in independent home visit roles. A valid driver's license is also required.
How much do home health nurses make in South Carolina?
Home health nurses in South Carolina earn a median of about $82,360 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $66,860 for the lowest 10% to over $106,520 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire home health nurses in South Carolina?
Companies currently hiring home health nurses in South Carolina include Amedisys, CenterWell, and Matrix Medical Network, per current listings on Migrate Mate as of October 2026. South Carolina's mix of large regional health systems and national home health chains means openings are distributed across urban centers like Columbia and Greenville as well as underserved rural counties.
Which South Carolina cities have the most home health nurse jobs?
Aiken, Columbia, and Rock Hill account for the highest concentration of home health nurse openings in South Carolina. Columbia's role as the state capital anchors large health systems and state-administered home care programs, while Greenville's expanding medical corridor and Charleston's growing retiree population drive consistent demand in those metros.
Are there remote home health nurse jobs in South Carolina?
Yes, but they're rare. About 81% of home health nurse openings tied to South Carolina are remote or hybrid as of October 2026, reflecting the hands-on nature of bedside and home visit care. The roles most likely to include a remote component are telephonic case management, care coordination, and utilization review positions attached to home health agencies.
How can I get hired as a home health nurse in South Carolina with little or no experience?
The most realistic entry path is completing a new graduate residency or clinical transition program at a South Carolina health system such as Prisma Health or MUSC, which place new nurses in supervised home health rotations. From there, lateral moves from med-surg, rehabilitation, or long-term care units into home health are common. Holding a current South Carolina Board of Nursing RN license and a home health aide or case management certificate strengthens an entry-level application considerably.
Where can I find and apply to home health nurse jobs in South Carolina?
You can find and apply to home health nurse jobs in South Carolina on Migrate Mate, which lists current openings across the state. Search the listings, identify the roles that match your credentials and preferred location, and apply directly to whichever ones fit your situation.
See All 122+ Home Health Nurse Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find Home Health Nurse Jobs