Respiratory Therapist Jobs in South Carolina

Respiratory Therapist jobs in South Carolina are concentrated in acute care hospitals, cardiopulmonary units, and long-term acute care facilities, with steady demand from new-graduate to senior clinician level. The largest hiring activity is in Columbia, Greenville, and Charleston, where systems like Prisma Health, Bon Secours, and MUSC Health maintain consistent openings. The most in-demand specialties in the state are neonatal and pediatric respiratory care, critical care ventilator management, and pulmonary rehabilitation. See the openings below and apply to the ones that match your experience.

Find Respiratory Therapist Jobs

Overview

Open roles67
Top employerPrisma Health
Top cityGreenville, SC
Cities hiring25
Work type100% On-site
Top industryHealthcare

Showing 5 of 67+ Respiratory Therapist jobs

Tenet Healthcare
Lead Respiratory Therapist
We won't show you this job again
Tenet Healthcare
New 18h ago
Lead Respiratory Therapist
Tenet Healthcare
Rock Hill, South Carolina
Healthcare Administration
Patient Services & Wellbeing
Public Health
NRP Certification
10,000+

Have you applied for this role?

Spartanburg Regional Healthcare System
Respiratory Therapist (RRT) NICU
We won't show you this job again
Spartanburg Regional Healthcare System
Added 1d ago
Respiratory Therapist (RRT) NICU
Spartanburg Regional Healthcare System
Spartanburg, South Carolina
Healthcare Administration
Patient Services & Wellbeing
Social Work & Counseling
NRP Certification

Have you applied for this role?

Prisma Health
Respiratory Therapist PT Variable NICU
We won't show you this job again
Prisma Health
Added 2d ago
Respiratory Therapist PT Variable NICU
Prisma Health
Greenville, South Carolina
Healthcare Administration
Human Resources
Patient Services & Wellbeing
NRP Certification
10,000+

Have you applied for this role?

Prisma Health
Respiratory Therapist FT Nights NICU
We won't show you this job again
Prisma Health
Added 2d ago
Respiratory Therapist FT Nights NICU
Prisma Health
Greenville, South Carolina
Healthcare Administration
Human Resources
Patient Services & Wellbeing
NRP Certification
10,000+

Have you applied for this role?

V
Travel Respiratory Therapist
We won't show you this job again
V
Added 2d ago
Travel Respiratory Therapist
Voyage Health
Columbia, South Carolina
Healthcare Administration
Mental & Behavioral Health
Social Work & Counseling
$1,789 - $1,883/yr

Have you applied for this role?

See All 67 Respiratory Therapist Jobs in South Carolina

Find roles in South Carolina that match your experience and apply in just a few clicks.

Find Respiratory Therapist Jobs

Respiratory Therapist Jobs by City in South Carolina

Where South Carolina roles are concentrated, by current openings.

Greenville
9 jobs
Columbia
6 jobs
Florence
6 jobs
Charleston
6 jobs
Spartanburg
6 jobs
Walterboro
4 jobs
Greer
3 jobs
Myrtle Beach
3 jobs
Aiken
2 jobs

Respiratory Therapist Job Market in South Carolina

A snapshot from current South Carolina openings, updated as new roles post.

Who's Hiring

  • Prisma Health
    Prisma Health13
  • V
    Voyage Health12
  • Spartanburg Regional Healthcare System
    Spartanburg Regional Healthcare System9
  • McLeod Health
    McLeod Health5
  • American Traveler
    American Traveler3

Top Industries Hiring

  • Healthcare & Medical Services

What South Carolina Employers Look For

The qualifications that appear most often in respiratory therapist jobs across South Carolina.

  • Active South Carolina respiratory care practitioner license issued by the South Carolina Board of Medical Examiners
  • Registered Respiratory Therapist credential from the National Board for Respiratory Care
  • Associate or bachelor's degree in respiratory care from a CAAHEP-accredited program
  • Current BLS certification and ACLS certification for critical care or ICU settings
  • Hands-on experience with mechanical ventilation, arterial blood gas interpretation, and airway management
  • Ability to work rotating shifts including nights, weekends, and holidays in hospital environments

Respiratory Therapist Jobs in South Carolina: Frequently Asked Questions

How do you become a respiratory therapist in South Carolina?

You must hold an active respiratory care practitioner license issued by the South Carolina Board of Medical Examiners to practice in the state. The path starts with completing an accredited respiratory care program, then passing the Therapist Multiple-Choice and Clinical Simulation exams administered by the National Board for Respiratory Care to earn the Registered Respiratory Therapist credential. Once credentialed, you apply for a South Carolina license before beginning employment.

How much do respiratory therapists make in South Carolina?

Respiratory therapists in South Carolina earn a median of about $77,740 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $63,700 for the lowest 10% to over $90,670 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire respiratory therapists in South Carolina?

South Carolina respiratory therapist roles are posted by Prisma Health, Voyage Health, and Spartanburg Regional Healthcare System and others right now, based on current listings on Migrate Mate as of August 2026. Large integrated health systems with multiple campuses across the state, including rural and community hospitals, tend to post the most consistent volume of openings.

Which South Carolina cities have the most respiratory therapist jobs?

Greenville, Columbia, and Florence have the most respiratory therapist openings in South Carolina. Columbia anchors hiring as the state capital and home to major academic medical centers, Greenville drives demand through its large and expanding Upstate hospital corridor, and Charleston's concentration of teaching hospitals and specialty care facilities, including MUSC Health, sustains strong ongoing recruitment.

Are there remote respiratory therapist jobs in South Carolina?

Yes, but they're rare. Respiratory therapy is a hands-on clinical role that requires direct patient contact, so the large majority of positions are fully on-site. About 0% of respiratory therapist openings tied to South Carolina are remote or hybrid as of August 2026, and those tend to be in telehealth respiratory monitoring or case management roles rather than direct bedside care.

How can I get hired as a respiratory therapist in South Carolina with little or no experience?

The most realistic entry point is a new-graduate staff position at a large health system that offers structured orientation programs, such as those at Prisma Health or MUSC Health, which regularly onboard candidates directly from accredited programs. Completing a clinical rotation at a South Carolina facility during your program gives you a direct hiring advantage. Candidates moving from roles like respiratory therapy technician or emergency medical technician can also transition into staff therapist openings, especially at community hospitals with higher turnover.

Where can I find and apply to respiratory therapist jobs in South Carolina?

You can find and apply to respiratory therapist jobs in South Carolina on Migrate Mate, which lists current openings across the state. Search the listings to find roles that fit your credentials, experience level, and preferred location, then apply directly to the ones that match.

See All 67 Respiratory Therapist Jobs in South Carolina

Find roles in South Carolina that match your experience and apply in just a few clicks.

Find Respiratory Therapist Jobs