Nursing Supervisor Jobs in South Carolina
Nursing Supervisor jobs in South Carolina are concentrated in Columbia, Charleston, and Greenville, where major health systems such as MUSC Health, Prisma Health, and Bon Secours St. Francis maintain large inpatient and outpatient campuses that rely on experienced supervisory staff. Demand is strongest in med-surg, critical care, and behavioral health, with openings at every seniority level from charge nurse stepping into supervision to seasoned directors overseeing multi-unit teams. South Carolina's growing coastal and upstate populations have made it one of the Southeast's more active markets for clinical leadership talent. Find a role that fits below and apply directly.
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Position: Night Shift Supervisor, Registered Nurse (RN)
Are you looking to make a difference in the lives of others by sharing your care and compassion? Do you enjoy connecting with your patients while getting to know them and their families? Do you enjoy working in a family-oriented atmosphere? Come join our family-oriented team at NHC HealthCare Charleston! NHC fosters an environment of teamwork and provides opportunities to use your comprehensive Nursing Tools.
Position Highlights:
- Is responsible for maintaining clinical competency as evidenced by the application of integrated nursing knowledge and skills, leadership and communication skills.
- Utilizes the nursing process in assessment, planning, and implementing care.
- Exhibits organizational ability related to workflow, prioritizing to meet the patient care needs
- Integrates current standards of practice as well as local, state, and federal regulations related to nursing services in the care of patients.
- Practices continuous quality improvement thinking and problem-solving skills.
Why NHC?
We offer a culture of recognition, empowerment, and fun. At NHC, we are all partners (employees) in a family-oriented work atmosphere where growth and opportunities are promoted. We provide competitive compensation with performance wage rate increases.
Work Schedule: PM Shift
Job Type: Full Time
Experience
South Carolina RN Nursing license
Benefits
Earned Time Off
Holiday Incentive Pay
Health, Dental, Vision, Disability and Life insurance
401k with generous company contributions
Competitive Pay
Uniforms
Tuition Reimbursement Opportunities
Advancement Opportunities
Work Location:
NHC HealthCare Charleston
2230 Ashley Crossing Drive
Charleston, SC 29414
If you are interested in working for a leader in senior care, share NHC's values of honesty and integrity, and have a heart for the geriatric patient, please apply today and find out more about us at nhccare.com/locations/charleston/ (https://nhccare.com/locations/charleston/)
EOE
Equal Opportunity Employer
This employer is required to notify all applicants of their rights pursuant to federal employment laws. For further information, please review the Know Your Rights (https://www.eeoc.gov/poster) notice from the Department of Labor.
See All 13 Nursing Supervisor Jobs in South Carolina
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Find Nursing Supervisor JobsNursing Supervisor Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Nursing Supervisor Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Healthcare & Medical Services
What South Carolina Employers Look For
The qualifications that appear most often in nursing supervisor jobs across South Carolina.
- Active registered nurse license recognized by the South Carolina Board of Nursing
- Minimum of three to five years of clinical nursing experience in an acute care setting
- Prior charge nurse, team lead, or supervisory responsibility in a hospital or facility
- Bachelor of Science in Nursing with a Master of Science in Nursing preferred for larger systems
- Proficiency with electronic health record platforms such as Epic or Meditech
- Strong knowledge of Joint Commission standards, staffing ratios, and regulatory compliance
Nursing Supervisor Jobs in South Carolina: Frequently Asked Questions
How do you become a nursing supervisor in South Carolina?
You must hold an active registered nurse license issued or recognized by the South Carolina Board of Nursing, which requires passing the NCLEX-RN exam. Most employers also expect a Bachelor of Science in Nursing and several years of direct clinical experience before moving into a supervisory role. Earning a certification such as Nurse Executive through the American Nurses Credentialing Center strengthens candidacy and is increasingly expected at larger South Carolina health systems.
Which companies hire nursing supervisors in South Carolina?
South Carolina nursing supervisor roles are posted by McLeod Health, Saber Healthcare, and Ethos Veterinary Health and others right now, based on current listings on Migrate Mate as of October 2026. South Carolina's largest hiring activity comes from integrated health systems with multiple campuses across Columbia, Charleston, and the Upstate region.
Which South Carolina cities have the most nursing supervisor jobs?
Union, Charleston, and Greenville have the most nursing supervisor openings in South Carolina right now. Columbia leads because it is home to large academic medical centers and state government health facilities, while Charleston's growth as a regional destination has expanded MUSC Health's footprint considerably, and Greenville's Upstate corridor has grown rapidly around Prisma Health and a cluster of specialty and rehabilitation facilities.
Are there remote nursing supervisor jobs in South Carolina?
Yes, but they're rare. About 0% of nursing supervisor openings tied to South Carolina are remote or hybrid as of October 2026, which reflects how hands-on the role is by nature. The portions most likely to allow remote or hybrid scheduling are administrative duties such as scheduling, compliance reporting, and staff education, while direct floor oversight remains on-site.
How can I get hired as a nursing supervisor in South Carolina with little or no experience?
The most realistic path is moving into a charge nurse or assistant nurse manager role first, which large South Carolina employers such as Prisma Health and MUSC Health routinely use as a pipeline for supervisory staff. Completing a nurse leadership residency or a unit-based preceptorship at one of these systems builds the competencies hospitals look for before promoting into full supervision. Holding a BSN and pursuing a Nurse Executive certification signals readiness even when formal supervisory hours are limited.
Where can I find and apply to nursing supervisor jobs in South Carolina?
You can find and apply to nursing supervisor jobs in South Carolina on Migrate Mate, which lists current openings from employers across the state. Find the roles that fit your experience and specialization and apply directly from each listing.
See All 13 Nursing Supervisor Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find Nursing Supervisor Jobs