Nursing Supervisor Jobs in South Carolina

Nursing Supervisor jobs in South Carolina are concentrated in Columbia, Charleston, and Greenville, where major health systems such as MUSC Health, Prisma Health, and Bon Secours St. Francis maintain large inpatient and outpatient campuses that rely on experienced supervisory staff. Demand is strongest in med-surg, critical care, and behavioral health, with openings at every seniority level from charge nurse stepping into supervision to seasoned directors overseeing multi-unit teams. South Carolina's growing coastal and upstate populations have made it one of the Southeast's more active markets for clinical leadership talent. Find a role that fits below and apply directly.

Find Nursing Supervisor Jobs

Overview

Open roles13
Top employerMcLeod Health
Top cityUnion, SC
Cities hiring9
Work type100% On-site
Top industryHealthcare

Showing 5 of 13+ Nursing Supervisor jobs

Night Shift Nursing Supervisor, RN Registered Nurse
We won't show you this job again
Added 1d ago
Night Shift Nursing Supervisor, RN Registered Nurse
National HealthCare Corporation
Charleston, South Carolina
Healthcare Administration
Nursing
Patient Services & Wellbeing
10,000+

Have you applied for this role?

Emergency Critical Care Veterinary Nursing Supervisor
We won't show you this job again
Added 1w ago
Emergency Critical Care Veterinary Nursing Supervisor
Ethos Veterinary Health
Charleston, South Carolina
Clinical Support
Healthcare Administration
Mental & Behavioral Health
$34 - $40/hr
Veterinary Technician Certification
10,000+

Have you applied for this role?

Overnight Emergency Veterinary Nursing Supervisor
We won't show you this job again
Added 2w ago
Overnight Emergency Veterinary Nursing Supervisor
Ethos Veterinary Health
Greenville, South Carolina
Clinical Support
Healthcare Administration
Human Resources
Nursing
$30 - $35/hr
Managed Registered Nurses (RNs)
10,000+

Have you applied for this role?

Evening Nursing Supervisor
We won't show you this job again
Added 1mo ago
Evening Nursing Supervisor
Lila Doyle Post Acute
Seneca, South Carolina
Healthcare Administration
Nursing
Patient Services & Wellbeing
On-Site

Have you applied for this role?

Administrative Supervisor, PRN, DAYS, Nursing Administration, Clarendon
We won't show you this job again
Added 1mo ago
Administrative Supervisor, PRN, DAYS, Nursing Administration, Clarendon
McLeod Health
Manning, South Carolina
Customer Service
Customer Support
Hospitality & Guest Services
NRP Certification
10,000+

Have you applied for this role?

See All 13 Nursing Supervisor Jobs in South Carolina

Find roles in South Carolina that match your experience and apply in just a few clicks.

Find Nursing Supervisor Jobs

Nursing Supervisor Jobs by City in South Carolina

Where South Carolina roles are concentrated, by current openings.

Union
2 jobs
Charleston
2 jobs
Greenville
2 jobs
Spartanburg
2 jobs
Conway
1 job
Seneca
1 job
Manning
1 job
Florence
1 job
Rock Hill
1 job

Nursing Supervisor Job Market in South Carolina

A snapshot from current South Carolina openings, updated as new roles post.

Who's Hiring

McLeod Health2 open roles
Saber Healthcare2 open roles
Ethos Veterinary Health2 open roles

Top Industries Hiring

  • Healthcare & Medical Services

What South Carolina Employers Look For

The qualifications that appear most often in nursing supervisor jobs across South Carolina.

  • Active registered nurse license recognized by the South Carolina Board of Nursing
  • Minimum of three to five years of clinical nursing experience in an acute care setting
  • Prior charge nurse, team lead, or supervisory responsibility in a hospital or facility
  • Bachelor of Science in Nursing with a Master of Science in Nursing preferred for larger systems
  • Proficiency with electronic health record platforms such as Epic or Meditech
  • Strong knowledge of Joint Commission standards, staffing ratios, and regulatory compliance

Nursing Supervisor Jobs in South Carolina: Frequently Asked Questions

How do you become a nursing supervisor in South Carolina?

You must hold an active registered nurse license issued or recognized by the South Carolina Board of Nursing, which requires passing the NCLEX-RN exam. Most employers also expect a Bachelor of Science in Nursing and several years of direct clinical experience before moving into a supervisory role. Earning a certification such as Nurse Executive through the American Nurses Credentialing Center strengthens candidacy and is increasingly expected at larger South Carolina health systems.

Which companies hire nursing supervisors in South Carolina?

South Carolina nursing supervisor roles are posted by McLeod Health, Saber Healthcare, and Ethos Veterinary Health and others right now, based on current listings on Migrate Mate as of October 2026. South Carolina's largest hiring activity comes from integrated health systems with multiple campuses across Columbia, Charleston, and the Upstate region.

Which South Carolina cities have the most nursing supervisor jobs?

Union, Charleston, and Greenville have the most nursing supervisor openings in South Carolina right now. Columbia leads because it is home to large academic medical centers and state government health facilities, while Charleston's growth as a regional destination has expanded MUSC Health's footprint considerably, and Greenville's Upstate corridor has grown rapidly around Prisma Health and a cluster of specialty and rehabilitation facilities.

Are there remote nursing supervisor jobs in South Carolina?

Yes, but they're rare. About 0% of nursing supervisor openings tied to South Carolina are remote or hybrid as of October 2026, which reflects how hands-on the role is by nature. The portions most likely to allow remote or hybrid scheduling are administrative duties such as scheduling, compliance reporting, and staff education, while direct floor oversight remains on-site.

How can I get hired as a nursing supervisor in South Carolina with little or no experience?

The most realistic path is moving into a charge nurse or assistant nurse manager role first, which large South Carolina employers such as Prisma Health and MUSC Health routinely use as a pipeline for supervisory staff. Completing a nurse leadership residency or a unit-based preceptorship at one of these systems builds the competencies hospitals look for before promoting into full supervision. Holding a BSN and pursuing a Nurse Executive certification signals readiness even when formal supervisory hours are limited.

Where can I find and apply to nursing supervisor jobs in South Carolina?

You can find and apply to nursing supervisor jobs in South Carolina on Migrate Mate, which lists current openings from employers across the state. Find the roles that fit your experience and specialization and apply directly from each listing.

See All 13 Nursing Supervisor Jobs in South Carolina

Find roles in South Carolina that match your experience and apply in just a few clicks.

Find Nursing Supervisor Jobs