Clinic Registered Nurse Jobs in Missouri
Clinic Registered Nurse jobs in Missouri are consistently in demand, with strong hiring across primary care clinics, federally qualified health centers, and specialty outpatient practices. Kansas City and St. Louis anchor most of the volume, with Columbia also an active market, and major systems like BJC HealthCare, Saint Luke's Health System, and Mercy Health drive a significant share of openings statewide. Family practice, chronic disease management, and pediatric clinic nursing are the sub-areas seeing the steadiest flow of new postings. Find a role that fits below and apply directly.
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- Creve Coeur, Missouri
- Nursing
- Nursing
- Regular
- Full-time
- Mercy Hospital St Louis
- JR266204
Job Description
Find your calling at Mercy!
OverviewProvides professional nursing care to patients within the medical practice in support of, and as directed by, the physicians. Assists the physician in the treatment of patients and completes related clinical paperwork. The incumbent in this position shall carry out his or her responsibilities and integrate into his or her work ethic the Mercy Philosophy of caring for the sick and suffering, respect for human life and the dignity of each person, applying Christian values to all crucial human issues in the area over which he or she has responsibility. In communicating with patients, families, visitors and employees, a caring, friendly, personal and professional approach is expected. Performs related duties as assigned. All the duties, responsibilities and qualification documented in this job description are subject to reasonable accommodation. This job description is not to be construed as a detailed statement of duties, responsibilities or requirements. Employees of St. Johns Health System are expected to comply with all federal, state and local regulations in addition to organization policy and procedures.
Position Details:
Qualifications
Education: Graduation from an accredited school of nursing. Knowledge of the principles and skills needed for nursing, care, examination, diagnostic and treatment room procedures. Knowledge of medications and their effects, patient education, principles to develop a self-care program, instruments and common safety practices.
Licensure: Current valid state license.
Experience: Not required.
Certifications: CPR certification or obtain within 90 days of employment.
Other: Skills, Knowledge, and Abilities: Skill in assisting and performing a variety of medical treatments and procedures. Ability to react calmly and effectively in emergency situations. Must be able to interpret, adapt and apply guidelines and policies. Must be able to communicate clearly and establish and maintain effective working relationships with patients, staff and the public. Basic computer terminal and keyboard skills, or the ability to learn these skills, in order to access information and enter clinical data. Equipment Used: Must be able to operate equipment normally related to the specialty of the clinic.
Why Mercy?
From day one, Mercy offers outstanding benefits - including medical, dental, and vision coverage, paid time off, tuition support, and matched retirement plans for team members working 32+ hours per pay period.
Join a caring, collaborative team where your voice matters. At Mercy, you'll help shape the future of healthcare through innovation, technology, and compassion. As we grow, you'll grow with us.
See All 60 Clinic Registered Nurse Jobs in Missouri
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Find Clinic Registered Nurse JobsClinic Registered Nurse Jobs by City in Missouri
Where Missouri roles are concentrated, by current openings.
Clinic Registered Nurse Job Market in Missouri
A snapshot from current Missouri openings, updated as new roles post.
Who's Hiring
- SSM Health11

- Saint Luke's8

- The University of Kansas Health System7

- Mercy5

- University of Missouri Health Care5

Top Industries Hiring
- Healthcare & Medical Services
What Missouri Employers Look For
The qualifications that appear most often in clinic registered nurse jobs across Missouri.
- Active registered nurse license issued or recognized by the Missouri State Board of Nursing
- Associate or Bachelor of Science in Nursing degree from an accredited program
- Current BLS certification required prior to patient care start date
- One or more years of clinical nursing experience in an outpatient or ambulatory setting
- Proficiency with electronic health record systems such as Epic or Cerner
- Strong patient assessment and care coordination skills for high-volume clinic environments
Clinic Registered Nurse Jobs in Missouri: Frequently Asked Questions
How do you become a clinic registered nurse in Missouri?
You become a clinic registered nurse in Missouri by earning an Associate Degree in Nursing or a Bachelor of Science in Nursing from an accredited program, passing the NCLEX-RN, and obtaining a license through the Missouri State Board of Nursing. Missouri participates in the Nurse Licensure Compact, so nurses licensed in other compact states can work in Missouri without a separate state license. Most clinic employers also expect current BLS certification before the first day.
How much do clinic registered nurses make in Missouri?
Clinic registered nurses in Missouri earn a median of about $81,780 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $63,230 for the lowest 10% to over $104,390 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire clinic registered nurses in Missouri?
Missouri clinic registered nurse roles are posted by SSM Health, Saint Luke's, and The University of Kansas Health System and others right now, based on current listings on Migrate Mate as of August 2026. Missouri's mix of large integrated health systems, independent specialty clinics, and federally qualified health centers means openings are distributed across both major metros and smaller regional communities statewide.
Which Missouri cities have the most clinic registered nurse jobs?
Kansas City, St. Louis, and Liberty are the Missouri cities with the most clinic registered nurse openings. St. Louis and Kansas City lead because of the large hospital systems and specialty clinic networks headquartered there, while Columbia's concentration of academic medicine and University of Missouri Health Care drives a disproportionately large number of openings relative to its population.
Are there remote clinic registered nurse jobs in Missouri?
Yes, but they're rare. Clinic nursing is inherently hands-on, so most roles require on-site patient care. About 20% of clinic registered nurse openings tied to Missouri are remote or hybrid as of August 2026, and those positions tend to be in telephone triage, care management, or chronic disease coaching rather than direct patient examination.
How can I get hired as a clinic registered nurse in Missouri with little or no experience?
The most realistic entry path is a new-graduate residency or transition-to-practice program at a large Missouri health system. BJC HealthCare, Mercy Health, and Saint Luke's Health System run structured new-grad programs that include outpatient and clinic rotations. Candidates coming from medical assistant, licensed practical nurse, or patient care technician roles have a strong advantage because those lateral moves demonstrate clinic workflow familiarity. Holding an active Missouri nursing license or Nurse Licensure Compact license before applying, combined with BLS certification, is the credential combination that most quickly moves a new-grad application forward.
Where can I find and apply to clinic registered nurse jobs in Missouri?
You can find and apply to clinic registered nurse jobs in Missouri on Migrate Mate, which lists current Missouri openings across health systems, specialty clinics, and community health centers. Find the roles that fit your experience and location and apply directly.
See All 60 Clinic Registered Nurse Jobs in Missouri
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