Clinic Registered Nurse Jobs in Missouri

Clinic Registered Nurse jobs in Missouri are consistently in demand, with strong hiring across primary care clinics, federally qualified health centers, and specialty outpatient practices. Kansas City and St. Louis anchor most of the volume, with Columbia also an active market, and major systems like BJC HealthCare, Saint Luke's Health System, and Mercy Health drive a significant share of openings statewide. Family practice, chronic disease management, and pediatric clinic nursing are the sub-areas seeing the steadiest flow of new postings. Find a role that fits below and apply directly.

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Overview

Open roles60
Top employerSSM Health
Top cityKansas City, MO
Cities hiring28
Work type80% On-site
Top industryHealthcare

Showing 5 of 60+ Clinic Registered Nurse jobs

Mercy
RN Specialty Clinic - ENT Clinic (F/T Days Pratt Cancer Center)
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Mercy
New 11h ago
RN Specialty Clinic - ENT Clinic (F/T Days Pratt Cancer Center)
Mercy
Creve Coeur, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
CPR Certification
10,000+

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University of Missouri Health Care
RN - Clinic Core Charge Nurse - Ashland Family Medicine
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University of Missouri Health Care
Added 1d ago
RN - Clinic Core Charge Nurse - Ashland Family Medicine
University of Missouri Health Care
Ashland, Missouri
Executive Leadership & C-Suite
Program Management
Project Management
$29.77 - $43.93/hr
Managed Registered Nurses (RNs)
5,001-10,000

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Community Hospital - Fairfax
Outpatient Clinic Registered Nurse
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Community Hospital - Fairfax
Added 1d ago
Outpatient Clinic Registered Nurse
Community Hospital - Fairfax
Fairfax, Missouri
Customer Service
Customer Support
Hospitality & Guest Services
$31.72 - $40/hr
BLS Certification
51-200

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SSM Health
Registered Nurse - Urology Clinic
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SSM Health
Added 1d ago
Registered Nurse - Urology Clinic
SSM Health
Lake Saint Louis, Missouri
Customer Service
Customer Support
Hospitality & Guest Services
BLS Certification
10,000+

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Saint Luke's
Registered Nurse - Clinic Float
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Saint Luke's
Added 1d ago
Registered Nurse - Clinic Float
Saint Luke's
Kansas City, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
BLS Certification
10,000+

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See All 60 Clinic Registered Nurse Jobs in Missouri

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Clinic Registered Nurse Jobs by City in Missouri

Where Missouri roles are concentrated, by current openings.

Kansas City
14 jobs
St. Louis
9 jobs
Liberty
4 jobs
Columbia
4 jobs
Eureka
2 jobs
Fenton
2 jobs
Bridgeton
2 jobs
Springfield
2 jobs
Fulton
1 job

Clinic Registered Nurse Job Market in Missouri

A snapshot from current Missouri openings, updated as new roles post.

Who's Hiring

  • SSM Health
    SSM Health11
  • Saint Luke's
    Saint Luke's8
  • The University of Kansas Health System
    The University of Kansas Health System7
  • Mercy
    Mercy5
  • University of Missouri Health Care
    University of Missouri Health Care5

Top Industries Hiring

  • Healthcare & Medical Services

What Missouri Employers Look For

The qualifications that appear most often in clinic registered nurse jobs across Missouri.

  • Active registered nurse license issued or recognized by the Missouri State Board of Nursing
  • Associate or Bachelor of Science in Nursing degree from an accredited program
  • Current BLS certification required prior to patient care start date
  • One or more years of clinical nursing experience in an outpatient or ambulatory setting
  • Proficiency with electronic health record systems such as Epic or Cerner
  • Strong patient assessment and care coordination skills for high-volume clinic environments

Clinic Registered Nurse Jobs in Missouri: Frequently Asked Questions

How do you become a clinic registered nurse in Missouri?

You become a clinic registered nurse in Missouri by earning an Associate Degree in Nursing or a Bachelor of Science in Nursing from an accredited program, passing the NCLEX-RN, and obtaining a license through the Missouri State Board of Nursing. Missouri participates in the Nurse Licensure Compact, so nurses licensed in other compact states can work in Missouri without a separate state license. Most clinic employers also expect current BLS certification before the first day.

How much do clinic registered nurses make in Missouri?

Clinic registered nurses in Missouri earn a median of about $81,780 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $63,230 for the lowest 10% to over $104,390 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire clinic registered nurses in Missouri?

Missouri clinic registered nurse roles are posted by SSM Health, Saint Luke's, and The University of Kansas Health System and others right now, based on current listings on Migrate Mate as of August 2026. Missouri's mix of large integrated health systems, independent specialty clinics, and federally qualified health centers means openings are distributed across both major metros and smaller regional communities statewide.

Which Missouri cities have the most clinic registered nurse jobs?

Kansas City, St. Louis, and Liberty are the Missouri cities with the most clinic registered nurse openings. St. Louis and Kansas City lead because of the large hospital systems and specialty clinic networks headquartered there, while Columbia's concentration of academic medicine and University of Missouri Health Care drives a disproportionately large number of openings relative to its population.

Are there remote clinic registered nurse jobs in Missouri?

Yes, but they're rare. Clinic nursing is inherently hands-on, so most roles require on-site patient care. About 20% of clinic registered nurse openings tied to Missouri are remote or hybrid as of August 2026, and those positions tend to be in telephone triage, care management, or chronic disease coaching rather than direct patient examination.

How can I get hired as a clinic registered nurse in Missouri with little or no experience?

The most realistic entry path is a new-graduate residency or transition-to-practice program at a large Missouri health system. BJC HealthCare, Mercy Health, and Saint Luke's Health System run structured new-grad programs that include outpatient and clinic rotations. Candidates coming from medical assistant, licensed practical nurse, or patient care technician roles have a strong advantage because those lateral moves demonstrate clinic workflow familiarity. Holding an active Missouri nursing license or Nurse Licensure Compact license before applying, combined with BLS certification, is the credential combination that most quickly moves a new-grad application forward.

Where can I find and apply to clinic registered nurse jobs in Missouri?

You can find and apply to clinic registered nurse jobs in Missouri on Migrate Mate, which lists current Missouri openings across health systems, specialty clinics, and community health centers. Find the roles that fit your experience and location and apply directly.

See All 60 Clinic Registered Nurse Jobs in Missouri

Find roles in Missouri that match your experience and apply in just a few clicks.

Find Clinic Registered Nurse Jobs