Pharmacy Manager Jobs in South Carolina

Pharmacy Manager jobs in South Carolina are concentrated in retail pharmacy chains, health system outpatient pharmacies, and long-term care settings, with demand steady at every level from bench-experienced staff pharmacists stepping into leadership to seasoned multi-site directors. Columbia, Charleston, and Greenville account for the largest share of openings, anchored by employers such as Prisma Health, MUSC Health, and Walmart's extensive South Carolina retail footprint. Clinical pharmacy management, specialty pharmacy oversight, and PBM compliance expertise are the most sought-after areas across the state. Find a role that fits below and apply directly.

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Overview

Open roles38
Top employerWalgreens
Top cityColumbia, SC
Cities hiring26
Work type100% On-site
Top industryRetail

Showing 4 of 38+ Pharmacy Manager jobs

Clinical Pharmacy Manager
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Added 5d ago
Clinical Pharmacy Manager
HOPEHEALTH INC
Florence, South Carolina
Customer Service
Healthcare Administration
Human Resources
Overseeing health insurance pre-certification

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Pharmacy Operations Manager
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Added 5d ago
Pharmacy Operations Manager
Walgreens
Charleston, South Carolina
Customer Service
Customer Support
$22.5 - $35.75/hr
PTCB Certification
10,000+

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Full Time Assistant Pharmacy Manager
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Added 1w ago
Full Time Assistant Pharmacy Manager
Harris Teeter
Greenville, South Carolina
Business Development
Program Management
Project Management
CPR Certification

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Pharmacy Manager
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Added 1w ago
Pharmacy Manager
CVS Health
Orangeburg, South Carolina
Healthcare Administration
Human Resources
Pharmacy
$65 - $81/hr
10,000+

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See All 38 Pharmacy Manager Jobs in South Carolina

Find roles in South Carolina that match your experience and apply in just a few clicks.

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Pharmacy Manager Jobs by City in South Carolina

Where South Carolina roles are concentrated, by current openings.

Columbia
5 jobs
Charleston
4 jobs
Greenville
3 jobs
Clemson
2 jobs
Anderson
2 jobs
Florence
2 jobs
Irmo
1 job
Clover
1 job
Dillon
1 job

Pharmacy Manager Job Market in South Carolina

A snapshot from current South Carolina openings, updated as new roles post.

Who's Hiring

  • Walgreens15
  • Harris Teeter6
  • Walmart5
  • Prisma Health5
  • CVS Health4

Top Industries Hiring

  • Retail
  • Education
  • Healthcare & Medical Services

What South Carolina Employers Look For

The qualifications that appear most often in pharmacy manager jobs across South Carolina.

  • Active South Carolina pharmacist license issued by the South Carolina Board of Pharmacy required
  • Doctor of Pharmacy degree from an ACPE-accredited college of pharmacy
  • Minimum two years of staff pharmacist experience in a retail or clinical setting
  • Proven ability to manage pharmacy technicians, scheduling, and daily operations
  • Working knowledge of state and federal dispensing regulations and DEA compliance
  • Experience with pharmacy management software and inventory control systems

Pharmacy Manager Jobs in South Carolina: Frequently Asked Questions

How do you become a pharmacy manager in South Carolina?

You must hold an active pharmacist license issued by the South Carolina Board of Pharmacy, which requires graduating from an ACPE-accredited Doctor of Pharmacy program, completing an internship, and passing both the NAPLEX and MPJE exams. Most employers also expect several years of staff pharmacist experience before moving into a management role, and larger health systems may require completion of a pharmacy leadership development program or an administrative residency.

Which companies hire pharmacy managers in South Carolina?

Employers hiring pharmacy managers in South Carolina right now include Walgreens, Harris Teeter, and Walmart, based on current listings on Migrate Mate as of October 2026. Health systems, national retail chains, and specialty pharmacy operators all maintain ongoing pharmacy manager needs across the state's major metros.

Which South Carolina cities have the most pharmacy manager jobs?

Columbia, Charleston, and Greenville lead South Carolina in pharmacy manager openings. Columbia's concentration of large health systems and state government facilities drives volume in the Midlands, while Charleston's growth as a medical and academic hub anchors demand along the coast, and Greenville's expanding Upstate hospital corridor supports consistent hiring for both retail and clinical pharmacy leadership roles.

Are there remote pharmacy manager jobs in South Carolina?

Yes, but they're rare. About 0% of pharmacy manager openings tied to South Carolina are remote or hybrid as of October 2026, reflecting that most management duties require on-site oversight of dispensing operations, staff, and regulatory compliance. The exceptions tend to be roles in PBM operations, telepharmacy program management, and corporate pharmacy policy positions where supervision is handled digitally.

How can I get hired as a pharmacy manager in South Carolina with little or no experience?

The most realistic path is completing a pharmacy administration or leadership residency, which Prisma Health and MUSC Health both offer for recent PharmD graduates in South Carolina. Candidates without residency experience often move into management from senior staff pharmacist or pharmacy supervisor roles at retail chains or health system outpatient locations. Obtaining Board of Pharmacy Specialties certification in a clinical area strengthens any application and signals readiness for leadership responsibilities.

Where can I find and apply to pharmacy manager jobs in South Carolina?

You can find and apply to pharmacy manager jobs in South Carolina on Migrate Mate, which lists current South Carolina openings across retail, health system, specialty, and long-term care settings. Search the listings for roles that match your experience level and preferred location, then apply directly to the ones that fit.

See All 38 Pharmacy Manager Jobs in South Carolina

Find roles in South Carolina that match your experience and apply in just a few clicks.

Find Pharmacy Manager Jobs