Clinical Medical Assistant Jobs in South Carolina
Clinical Medical Assistant jobs in South Carolina are open across Columbia, Charleston, and Greenville and other South Carolina metros, with employers like Medical University of South Carolina, Prisma Health, and McLeod Health hiring at every experience level. Find a role that fits below and apply directly.
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Showing 5 of 278+ Clinical Medical Assistant jobs











Essential Functions
JOB DESCRIPTION
As a Medical Assistant working closely with physicians, you'll assess patient needs through history, observation, and analysis of diagnostic data. This includes performing direct patient care, preparing patients for examinations, and conducting specialized tests and procedures. Your role involves administering medications, providing patient education, scheduling appointments, and handling telephone consultations. Beyond nursing duties, you'll ensure clean and well-equipped examination rooms, manage medical supplies, and contribute to departmental QA projects. Your commitment to continuous learning and teamwork fosters a positive practice environment and supports multifaceted responsibilities.
Required Education/Experience
- High School Diploma/GED equivalent from an accredited school.
- At least one year experience in a physician’s office or other clinical setting.
- Must be Registered or State Certified as a Medical Assistant with an accrediting board.
About us
Founded in 1906, McLeod Health is a locally owned and managed, not for profit organization supported by the strength of more than 900 members on its medical staff and more than 2,900 licensed nurses. McLeod Health is also composed of approximately 15,000 team members and more than 90 physician practices throughout its 18-county service area. With seven hospitals, McLeod Health operates three Health and Fitness Centers, a Sports Medicine and Outpatient Rehabilitation Center, Hospice and Home Health Services. The system currently has 988 licensed beds, including Hospice and Behavioral Health. The hospitals within McLeod Health include: McLeod Regional Medical Center, McLeod Health Dillon, McLeod Health Loris, McLeod Health Seacoast, McLeod Health Cheraw, McLeod Health Clarendon and McLeod Behavioral Health.
About The Team
If you would enjoy working in a dynamic environment and are looking for an opportunity to become part of a stellar team of professionals, we invite you to apply online today. We are an equal opportunity employer.
See All 278+ Clinical Medical Assistant Jobs in South Carolina
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Find JobsClinical Medical Assistant Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Clinical Medical Assistant Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring
- Medical University of South Carolina92

- Prisma Health67

- McLeod Health33

- Lexington Health30

- Self Regional Healthcare20

Top Industries Hiring
- Healthcare & Medical Services217
- Education55
- Consulting & Professional Services7
- Biotechnology & Pharmaceuticals4
- Insurance1
What South Carolina Employers Look For
The qualifications that appear most often in clinical medical assistant jobs across South Carolina.
- Certified Medical Assistant (CMA) or Registered Medical Assistant (RMA) credential preferred
- Current CPR and Basic Life Support (BLS) certification required
- Experience with electronic health record systems such as Epic or eClinicalWorks
- Ability to perform phlebotomy, injections, and basic clinical procedures
- High school diploma or equivalent plus completion of an accredited medical assistant program
- Strong patient communication skills and ability to work in a fast-paced clinical environment
Clinical Medical Assistant Jobs in South Carolina: Frequently Asked Questions
How many clinical medical assistant jobs are there in South Carolina?
There are 278+ clinical medical assistant openings in South Carolina on Migrate Mate as of June 2026, with the most roles in Columbia, Charleston, and Greenville. New positions post regularly as employers across South Carolina hire.
How much do clinical medical assistants make in South Carolina?
Clinical medical assistants in South Carolina earn a median of about $41,160 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $34,730 for the lowest 10% to over $49,110 for the top 10%. Pay rises with experience, specialty, and employer.
Which South Carolina cities have the most clinical medical assistant jobs?
Columbia, Charleston, and Greenville have the most clinical medical assistant openings in South Carolina right now, with additional roles spread across smaller metros statewide.
Which companies hire clinical medical assistants in South Carolina?
Employers hiring clinical medical assistants in South Carolina include Medical University of South Carolina, Prisma Health, and McLeod Health, based on current listings on Migrate Mate as of June 2026.
Are there remote clinical medical assistant jobs in South Carolina?
Yes. About 0% of clinical medical assistant openings tied to South Carolina are remote or hybrid as of June 2026. The rest are on-site roles based in South Carolina metros.
How do I apply for clinical medical assistant jobs in South Carolina?
You can apply to clinical medical assistant jobs in South Carolina directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred South Carolina location, then apply to each one that fits.
See All 278+ Clinical Medical Assistant Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
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