Clinical Medical Assistant Jobs in South Carolina
Clinical Medical Assistant jobs in South Carolina concentrate in outpatient clinics, primary care practices, and specialty physician offices, with steady demand from entry-level through senior clinical roles across the state. The most active hiring markets are Columbia, Greenville, and Charleston, where established systems like Prisma Health, MUSC Health, and Bon Secours are among the largest and most consistent employers. The most in-demand specialties include family medicine, pediatrics, and cardiology support. See the openings below and apply to the ones that match your experience.
Find JobsOverview
Showing 5 of 15+ Clinical Medical Assistant jobs
Prisma Health Urgent Care - Delivering Quality Care with Purpose
Are you a passionate Medical Assistant looking for a dynamic and rewarding career? Join Prisma Health Urgent Care, where you'll make a meaningful impact in a fast-paced clinical environment while enjoying work-life balance and professional growth opportunities.
As a Medical Assistant, you will be a key part of our healthcare team, providing hands-on patient care and ensuring smooth clinic operations. This role is ideal for those who thrive in a high-energy, team-oriented setting and are committed to delivering exceptional care.
Why You'll Love Working Here:
- LIFE-Work Balance & Flexible Schedule: Full-time (3-day/12-hour shifts, 8 AM - 8 PM) – No overnight shifts, so you can prioritize both your career and personal life!
- Competitive Pay & Benefits: Medical, Dental, Vision, Prescription, Pet Insurance & more
- Paid Time Off & Holidays: Recharge and take care of yourself
- 401K with Company Match: Plan for your future
- Professional Growth: Certification reimbursement, leadership opportunities & professional development
- Wellness Support: Employee Assistance Program (EAP) & Wellness Initiatives
Key Responsibilities:
- Patient Preparation: Assist with preparing patients for examinations and treatments, ensuring they are comfortable and well-informed.
- Triage & Vital Signs: Perform triage and take vital signs accurately.
- Documenting Patient History: Obtain and document detailed patient history in our Electronic Medical Record (EMR) system in a timely manner.
- Lab Specimens: Collect routine laboratory specimens, including blood, urine, and oral swabs.
- Medication & Injections: Administer medications and non-intravenous injections, including intramuscular, subcutaneous, and intradermal injections.
- Clinical Procedures: Start IVs, place catheters, and perform splinting when necessary.
- Clinical & Laboratory Procedures: Perform basic clinical, aseptic, and laboratory procedures to support patient care.
- Occupational Medicine: Assist with our Occupational Medicine services, including drug screening, breath alcohol testing, audiograms, and pulmonary function testing, while adhering to company protocols.
- Compliance: Enforce and maintain healthcare regulatory requirements, including HIPAA and OSHA compliance.
- Administrative Duties: Perform office procedures and general administrative tasks; proficiently operate office medical equipment.
- Quality Assurance: Oversee compliance with quality assurance programs, CLIA waived laboratory requirements, and patient result trackers.
- Travel Requirement: Support staffing and operational needs by traveling to other Prisma Health Urgent Care locations as required.
Required Qualifications:
- Certification: Must be certified or registered as a Medical Assistant through an accredited organization (e.g., AMT for RMA/NHA or AAMA for CMA).
- Experience: 1+ year of healthcare experience preferred (urgent care or ER a plus); willing to train outstanding new graduates
- Skills: Proficiency in venipuncture, injections, and clinical procedures
- Technical Skills: Experience using Electronic Medical Records (EMR) software, EPIC preferred
- Flexibility: Ability to work 12-hour shifts, weekends, and holidays
- Team Player: A positive, proactive approach to patient care and collaboration
At Prisma Health Urgent Care, we believe in kindness, excellence, empowerment, resilience, and proactive service. If you’re looking for a career where your contributions truly matter, apply today and be part of something bigger!
INDMA
Licenses & Certifications
Preferred- Paramedic Certification
- EMT Certification
- Medical Assistant Cert
Equal Opportunity Employer
This employer is required to notify all applicants of their rights pursuant to federal employment laws. For further information, please review the Know Your Rights (https://www.eeoc.gov/poster) notice from the Department of Labor.
See All 15 Clinical Medical Assistant Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find JobsClinical Medical Assistant Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Clinical Medical Assistant Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring
Top Industries Hiring
- Healthcare & Medical Services
What South Carolina Employers Look For
The qualifications that appear most often in clinical medical assistant jobs across South Carolina.
- Certified Medical Assistant (CMA) or Registered Medical Assistant (RMA) credential preferred by most South Carolina employers
- Completion of an accredited medical assisting program from a South Carolina community college or technical school
- Hands-on experience with electronic health records, particularly Epic or Athenahealth platforms used in South Carolina practices
- Proficiency in clinical duties including phlebotomy, vital signs, EKG administration, and medication administration
- Strong knowledge of HIPAA compliance and South Carolina patient privacy standards
- Current CPR and Basic Life Support (BLS) certification required by most clinical employers
Clinical Medical Assistant Jobs in South Carolina: Frequently Asked Questions
How do you become a clinical medical assistant in South Carolina?
South Carolina does not require a state-issued license for clinical medical assistants, but most employers strongly prefer nationally recognized credentials such as the Certified Medical Assistant (CMA) through the AAMA or the Registered Medical Assistant (RMA) through AMT. Candidates typically complete an accredited medical assisting program at a South Carolina technical college, such as Trident Technical College or Midlands Technical College, before sitting for a national certification exam.
Which companies hire clinical medical assistants in South Carolina?
South Carolina clinical medical assistant roles are posted by Prisma Health Urgent Care, AnMed Health, and McLeod Health and others right now, based on current listings on Migrate Mate as of August 2026. Large integrated health systems anchored in South Carolina, including academic medical centers and regional multispecialty groups, generate the most consistent volume of openings across the state.
Which South Carolina cities have the most clinical medical assistant jobs?
Anderson, Greenville, and Conway have the most clinical medical assistant openings in South Carolina. Columbia leads as the state capital and home to major health systems, Greenville's rapid population growth has fueled expansion of outpatient and specialty clinics, and Charleston's concentration of academic medicine and military health facilities drives steady demand in the Lowcountry.
Are there remote clinical medical assistant jobs in South Carolina?
Yes, but they're rare. Clinical medical assistants primarily perform hands-on patient care tasks that require an in-person presence, so most roles are fully on-site. About 0% of clinical medical assistant openings tied to South Carolina are remote or hybrid as of August 2026, and those positions typically involve administrative or care coordination duties rather than direct patient-facing clinical work.
How can I get hired as a clinical medical assistant in South Carolina with little or no experience?
The most realistic entry path is completing a medical assisting program at one of South Carolina's technical colleges, such as Spartanburg Community College or Piedmont Technical College, which include clinical externship placements that often lead directly to job offers. Prisma Health and MUSC Health both offer new graduate and externship pathways for candidates without prior clinical experience. Candidates transitioning from roles like patient care technician, medical receptionist, or certified nursing assistant frequently move into clinical medical assistant positions with existing employers.
Where can I find and apply to clinical medical assistant jobs in South Carolina?
You can find and apply to clinical medical assistant jobs in South Carolina on Migrate Mate, which lists current openings from employers across the state. Search for roles that match your credentials, experience level, and preferred location, then apply directly to the ones that fit. No sign-up is required to see the listings.
See All 15 Clinical Medical Assistant Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find Jobs