Registered Nurse Supervisor Jobs in South Carolina
Registered Nurse Supervisor jobs in South Carolina are concentrated in acute care hospital systems, long-term care facilities, and behavioral health networks, with steady demand at every level from newly promoted charge nurses to senior nurse managers overseeing multi-unit departments. Columbia, Greenville, and Charleston are the largest hiring markets in the state, anchored by major systems such as MUSC Health, Prisma Health, and Tidelands Health. The most consistent openings are in medical-surgical, ICU, and emergency department supervision, with growing need in home health management. See the openings below and apply to the ones that match your experience.
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Overview
Are you a results-driven leader ready to make a meaningful impact to patients, caregivers, and your community? At Piedmont Medical Network - Rock Hill Hospital, were seeking an innovative and experienced healthcare leader to drive excellence and inspire our team towards exceptional patient outcomes and operational success.
At Piedmont Medical Network - Rock Hill Hospital, we understand that our greatest asset is our dedicated team of professionals. That’s why we offer more than a job – we provide a comprehensive benefit package that prioritizes your health, professional development, and work-life balance. The available plans and programs include:
- Medical, dental, vision, and life insurance
- 401(k) retirement savings plan with employer match
- Generous paid time off
- Career development and continuing education opportunities
- Health savings accounts, healthcare & dependent flexible spending accounts
- Voluntary benefits include pet insurance, legal insurance, accident and critical illness insurance, long term care, elder & childcare, auto & home insurance
Note: Eligibility for benefits may vary by location and is determined by employment status
Job Summary
***$20,000.00 Sign-On Bonus (Paid over 2 Years)***
The Clinical Supervisor in collaboration with the Director is responsible for the continuous safe operation of the assigned department including all aspects of patient care, staffing, fiscal responsibility and strategic goals of the unit. The Clinical Supervisor is a designated leader responsible for implementation, supervision, and evaluation of safe patient care while promoting a safe environment for employees, families, and visitors. The Clinical Supervisor maintains clinical and professional competency as appropriate to the ages, developmental stages, and special needs of the population. Service Excellence behavior is promoted at all times.
Responsibilities
- Demonstrates flexibility in responding to unpredicted situations, such as emergencies, assignment and staffing or schedule changes. Responds to crisis situations with confidence and clarity, delegating as appropriate to others on the team.
- Sets priorities independently, prepares assignments and duties at the beginning of each shift, adjusting and delegating as situations change on the unit as needed.
- Supports the growth and development of nursing personnel by facilitating assessment of educational needs on an ongoing basis. Takes an active role in educating staff when a need and/or opportunity is identified.
- Assists with evaluation and improvement of patient care by assuring an ongoing unit-based quality-monitoring program to include development and implementation of PI monitors and reports.
- Delegates shift duties appropriately including but not limited to chart checks, defib/refrigerator logs, abnormal lab follow up and documentation, cleaning and stocking rooms, checking rooms for outdated supplies, pulling trash/linen as needed
- Performs related duties as required.
Qualifications
- Required:
- Education: Associates degree in Nursing
-
Licensure/Certification:
- A valid Permanent Multi-State RN License from the state in which you reside is required
- Should you hold a RN license from another Compact state, you are required to apply for and obtain a Multi-State RN License from the state in which you reside within 30 days.
- American Heart Association BLS CPR
- must be obtained within 7 days of hire. CPI certification with orientation period.
- Other certifications required are determined by specific unit and is required within orientation period.
-
Preferred:
- Experience: 2-3 years of Acute Care or comparable experience with demonstrated leadership ability preferred.
Organization Description
Piedmont Medical Network has served the community of York County and beyond for more than 30 years. Piedmont Medical Network - Rock Hill Hospital is a 288-bed facility that has advanced equipment and experienced healthcare staff catering to the diverse needs of the community it serves. Services include preventive care, advanced heart and stroke care, maternity care and a Level III NICU. Piedmont Medical Network - Fort Mill Hospital opened in 2022 with 100-beds, advanced technology and a compassionate care team. The new hospital features a 24/7 Emergency Department, Intensive Care Unit, Medical/Surgical Unit, and a wide array of Surgical Services and Women's Services.
Piedmont Medical Network has been recognized for its elite level of safety by being awarded the Leapfrog Groups Hospital Safety Score and the Certified Zero Harm Award by SCHA (South Carolina Hospital Association) in collaboration with South Carolinas DHEC. The Cardiac Care program at PMC provides quality care and was designated as a Blue Distinction Center for Cardiac Care by BlueCross BlueShield and a Nationally Certified Cardiac Rehabilitation Program by the American Association of Cardiovascular and Pulmonary Rehabilitation. At Piedmont Medical Network, you can grow your career skills and be a vital member of our team dedicated to improving the health of the community. Join our team!
Employment practices will not be influenced or affected by an applicant’s or employee’s race, color, religion, sex (including pregnancy), national origin, age, disability, genetic information, sexual orientation, gender identity or expression, veteran status or any other legally protected status. Tenet will make reasonable accommodations for qualified individuals with disabilities unless doing so would result in an undue hardship.
Tenet participates in the E-Verify program. Follow the link below for additional information.
E-Verify: http://www.uscis.gov/e-verify
The employment practices of Tenet Healthcare and its companies comply with all applicable laws and regulations.
- Demonstrates flexibility in responding to unpredicted situations, such as emergencies, assignment and staffing or schedule changes. Responds to crisis situations with confidence and clarity, delegating as appropriate to others on the team.
- Sets priorities independently, prepares assignments and duties at the beginning of each shift, adjusting and delegating as situations change on the unit as needed.
- Supports the growth and development of nursing personnel by facilitating assessment of educational needs on an ongoing basis. Takes an active role in educating staff when a need and/or opportunity is identified.
- Assists with evaluation and improvement of patient care by assuring an ongoing unit-based quality-monitoring program to include development and implementation of PI monitors and reports.
- Delegates shift duties appropriately including but not limited to chart checks, defib/refrigerator logs, abnormal lab follow up and documentation, cleaning and stocking rooms, checking rooms for outdated supplies, pulling trash/linen as needed
- Performs related duties as required.
- Required:
- Education: Associates degree in Nursing
-
Licensure/Certification:
- A valid Permanent Multi-State RN License from the state in which you reside is required
- Should you hold a RN license from another Compact state, you are required to apply for and obtain a Multi-State RN License from the state in which you reside within 30 days.
- American Heart Association BLS CPR
- must be obtained within 7 days of hire. CPI certification with orientation period.
- Other certifications required are determined by specific unit and is required within orientation period.
-
Preferred:
- Experience: 2-3 years of Acute Care or comparable experience with demonstrated leadership ability preferred.
See All 37 Registered Nurse Supervisor Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find JobsRegistered Nurse Supervisor Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Registered Nurse Supervisor Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring


Top Industries Hiring
- Healthcare & Medical Services
What South Carolina Employers Look For
The qualifications that appear most often in registered nurse supervisor jobs across South Carolina.
- Active Registered Nurse license issued or recognized by the South Carolina Board of Nursing
- Minimum of three to five years of clinical nursing experience in an acute or post-acute setting
- Prior supervisory or charge nurse experience leading a team of nursing staff
- Bachelor of Science in Nursing preferred, with some positions requiring a master's degree
- Current BLS certification and, depending on unit, ACLS or other specialty certifications
- Strong competency in staff scheduling, performance evaluation, and regulatory compliance
Registered Nurse Supervisor Jobs in South Carolina: Frequently Asked Questions
How do you become a registered nurse supervisor in South Carolina?
You become a registered nurse supervisor in South Carolina by first holding an active RN license from the South Carolina Board of Nursing, earned after completing an accredited nursing program and passing the NCLEX-RN exam. From there, most employers require several years of clinical bedside experience before moving into a supervisory role. Completing a BSN or MSN strengthens your candidacy, and pursuing nursing leadership certifications adds a competitive edge.
Which companies hire registered nurse supervisors in South Carolina?
South Carolina registered nurse supervisor roles are posted by Tenet Healthcare, McLeod Health, and Saber Healthcare and others right now, based on current listings on Migrate Mate as of August 2026. South Carolina's large integrated health systems and regional medical centers account for the bulk of these openings, particularly in the Columbia, Greenville, and Charleston corridors.
Which South Carolina cities have the most registered nurse supervisor jobs?
Rock Hill, Fort Mill, and South Carolina have the highest concentration of registered nurse supervisor openings in South Carolina. Columbia leads as the state capital with a dense cluster of large hospital systems and veterans' health facilities, while Greenville's growth as a regional medical hub drives volume there, and Charleston's academic medical center environment at MUSC Health sustains consistent supervisor-level demand.
Are there remote registered nurse supervisor jobs in South Carolina?
Yes, but they're rare. Registered nurse supervisor roles are fundamentally hands-on positions that require physical presence to lead staff, conduct rounding, and manage patient-care operations. About 20% of registered nurse supervisor openings tied to South Carolina are remote or hybrid as of August 2026, and those positions tend to be in utilization review, case management oversight, or telehealth program coordination rather than direct unit supervision.
How can I get hired as a registered nurse supervisor in South Carolina with little or no experience?
The most realistic entry path is to move into a charge nurse or assistant nurse manager role first, which most large South Carolina hospital systems use as a feeder track to formal supervision. Prisma Health and MUSC Health both run structured nurse leadership development programs that give clinical nurses exposure to scheduling, compliance, and staff mentorship before a full promotion. Holding a current BLS certification, completing a leadership-focused nursing course, and working in a high-acuity unit such as ICU or emergency shorten the typical timeline considerably.
Where can I find and apply to registered nurse supervisor jobs in South Carolina?
You can find and apply to registered nurse supervisor jobs in South Carolina on Migrate Mate, which lists current openings across the state updated in real time. Search for roles that match your clinical background, experience level, and preferred location, then apply directly to the ones that fit.
See All 37 Registered Nurse Supervisor Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
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