Registered Nurse Supervisor Jobs in South Carolina

Registered Nurse Supervisor jobs in South Carolina are concentrated in acute care hospital systems, long-term care facilities, and behavioral health networks, with steady demand at every level from newly promoted charge nurses to senior nurse managers overseeing multi-unit departments. Columbia, Greenville, and Charleston are the largest hiring markets in the state, anchored by major systems such as MUSC Health, Prisma Health, and Tidelands Health. The most consistent openings are in medical-surgical, ICU, and emergency department supervision, with growing need in home health management. See the openings below and apply to the ones that match your experience.

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Overview

Open roles37
Top employerTenet Healthcare
Top cityRock Hill, SC
Cities hiring19
Work type80% On-site
Top industryHealthcare

Showing 5 of 37+ Registered Nurse Supervisor jobs

Tenet Healthcare
Registered Nurse (RN) Supervisor - Behavioral Health
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Tenet Healthcare
New 18h ago
Registered Nurse (RN) Supervisor - Behavioral Health
Tenet Healthcare
Rock Hill, South Carolina
Compliance & Legal
Executive Leadership & C-Suite
Legal Counsel
Managed Registered Nurses (RNs)
10,000+

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PruittHealth
RN Weekend Supervisor
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PruittHealth
Added 1d ago
RN Weekend Supervisor
PruittHealth
Rock Hill, South Carolina
Healthcare Administration
Nursing
Patient Services & Wellbeing
10,000+

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PruittHealth
Registered Nurse Supervisor
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PruittHealth
Added 2d ago
Registered Nurse Supervisor
PruittHealth
North Augusta, South Carolina
Nursing
Healthcare Administration
Patient Services & Wellbeing
On-Site
None
10,000+

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Lighthouse Behavioral Health Hospital
Registered Nurse Supervisor- Nights
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Lighthouse Behavioral Health Hospital
Added 5d ago
Registered Nurse Supervisor- Nights
Lighthouse Behavioral Health Hospital
Conway, South Carolina
Healthcare Administration
Nursing
Patient Services & Wellbeing
Managed Registered Nurses (RNs)

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Blue Cross Blue Shield
RN Case Management Supervisor
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Blue Cross Blue Shield
Added 5d ago
RN Case Management Supervisor
Blue Cross Blue Shield
South Carolina
Customer Service
Customer Support
Hospitality & Guest Services
Remote (US)
Managed Registered Nurses (RNs)
1,001-5,000

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See All 37 Registered Nurse Supervisor Jobs in South Carolina

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Registered Nurse Supervisor Jobs by City in South Carolina

Where South Carolina roles are concentrated, by current openings.

Rock Hill
5 jobs
Fort Mill
3 jobs
Aiken
2 jobs
Greer
2 jobs
Sumter
2 jobs
Columbia
2 jobs
Florence
2 jobs
Greenville
2 jobs
Spartanburg
2 jobs

Registered Nurse Supervisor Job Market in South Carolina

A snapshot from current South Carolina openings, updated as new roles post.

Who's Hiring

Tenet Healthcare
Tenet Healthcare7 open roles
McLeod Health
McLeod Health3 open roles
S
Saber Healthcare3 open roles

Top Industries Hiring

  • Healthcare & Medical Services

What South Carolina Employers Look For

The qualifications that appear most often in registered nurse supervisor jobs across South Carolina.

  • Active Registered Nurse license issued or recognized by the South Carolina Board of Nursing
  • Minimum of three to five years of clinical nursing experience in an acute or post-acute setting
  • Prior supervisory or charge nurse experience leading a team of nursing staff
  • Bachelor of Science in Nursing preferred, with some positions requiring a master's degree
  • Current BLS certification and, depending on unit, ACLS or other specialty certifications
  • Strong competency in staff scheduling, performance evaluation, and regulatory compliance

Registered Nurse Supervisor Jobs in South Carolina: Frequently Asked Questions

How do you become a registered nurse supervisor in South Carolina?

You become a registered nurse supervisor in South Carolina by first holding an active RN license from the South Carolina Board of Nursing, earned after completing an accredited nursing program and passing the NCLEX-RN exam. From there, most employers require several years of clinical bedside experience before moving into a supervisory role. Completing a BSN or MSN strengthens your candidacy, and pursuing nursing leadership certifications adds a competitive edge.

Which companies hire registered nurse supervisors in South Carolina?

South Carolina registered nurse supervisor roles are posted by Tenet Healthcare, McLeod Health, and Saber Healthcare and others right now, based on current listings on Migrate Mate as of August 2026. South Carolina's large integrated health systems and regional medical centers account for the bulk of these openings, particularly in the Columbia, Greenville, and Charleston corridors.

Which South Carolina cities have the most registered nurse supervisor jobs?

Rock Hill, Fort Mill, and South Carolina have the highest concentration of registered nurse supervisor openings in South Carolina. Columbia leads as the state capital with a dense cluster of large hospital systems and veterans' health facilities, while Greenville's growth as a regional medical hub drives volume there, and Charleston's academic medical center environment at MUSC Health sustains consistent supervisor-level demand.

Are there remote registered nurse supervisor jobs in South Carolina?

Yes, but they're rare. Registered nurse supervisor roles are fundamentally hands-on positions that require physical presence to lead staff, conduct rounding, and manage patient-care operations. About 20% of registered nurse supervisor openings tied to South Carolina are remote or hybrid as of August 2026, and those positions tend to be in utilization review, case management oversight, or telehealth program coordination rather than direct unit supervision.

How can I get hired as a registered nurse supervisor in South Carolina with little or no experience?

The most realistic entry path is to move into a charge nurse or assistant nurse manager role first, which most large South Carolina hospital systems use as a feeder track to formal supervision. Prisma Health and MUSC Health both run structured nurse leadership development programs that give clinical nurses exposure to scheduling, compliance, and staff mentorship before a full promotion. Holding a current BLS certification, completing a leadership-focused nursing course, and working in a high-acuity unit such as ICU or emergency shorten the typical timeline considerably.

Where can I find and apply to registered nurse supervisor jobs in South Carolina?

You can find and apply to registered nurse supervisor jobs in South Carolina on Migrate Mate, which lists current openings across the state updated in real time. Search for roles that match your clinical background, experience level, and preferred location, then apply directly to the ones that fit.

See All 37 Registered Nurse Supervisor Jobs in South Carolina

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