Registered Nurse Med Surg Jobs in South Carolina
Registered Nurse Med Surg jobs in South Carolina are concentrated in Charleston, Columbia, and Greenville, where systems like MUSC Health, Prisma Health, and Bon Secours operate large acute-care facilities with consistent med-surg units. Demand runs from new-graduate nurses to experienced charge nurses, with the strongest openings in post-surgical care, orthopedics, and cardiac step-down. South Carolina's growing retiree population and expanding suburban hospital campuses keep this one of the more active hiring markets in the Southeast. Find a role that fits below and apply directly.
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Showing 4 of 62+ Registered Nurse Med Surg jobs
Thank you for considering a career at Roper St. Francis Healthcare!
Shift Schedule
Every other weekend
Delivers patient care utilizing the nursing process through data collection and assessment, identifies and determines the priority of patient’s problems/needs, and evaluates the process and outcome of nursing care; coordinates, provides and directs patient teaching activities and coordinates the care provided by health team members.
Essential Job Functions
In collaboration with the interdisciplinary care team, conducts initial and ongoing patient assessment, analyzes assessment data, creates a plan of care, implements treatment and evaluates treatment effectiveness; administers medications in a safe manner consistent with the State of Practice and organization policies and procedures; serves as point of contact for patients' care coordination throughout hospital departments. Acts as a patient safety advocate by participating in ongoing quality improvement in the department. Incorporates the professional practice model into care delivery
Skills
- Knowledge of contemporary nursing practice and future innovations
- Nursing judgment and skill based on principles of the biological, physical, behavioral, and social sciences
- Application of the nursing process in patient care delivery
- Coordination of patient care delivery
- Evaluation of professional nursing practice to optimize goals and outcomes
- Health teaching and health promotion
- Patient advocacy and partnership
- Interprofessional collaboration and leadership
- Understanding and utilization of office and clinical technologies
- Compassionate, relationship-based approach to help find meaning in illness, suffering, pain, and existence
- Integration of quality improvement, evidence based practices and research in practice
- Accountability for professional actions
- Effective stewardship of available resources
- Conflict management and resilience
- Authority for delegating activities to others, while remaining responsible and accountable for outcomes
Certifications
BLS Basic Life Support, American Heart Association (required at hire for Roper St Francis Healthcare locations; preferred at hire, required prior to independent patient care at BSMH)
Valid nursing license from the state of practice (required)
Education
Associate of Nursing, nursing (required)
OR
Diploma in Nursing (required)
Bachelors of Science, nursing (preferred)
As a Roper St. Francis Healthcare teammate, you're part of a Mission that matters. We support your well-being—personally and professionally. Our benefits are built to grow with you and meet your unique needs, every step of the way.
What we offer
- Competitive pay, incentives, referral bonuses and 403(b) with employer contributions (when eligible)
- Medical, dental, vision, prescription coverage, HSA/FSA options, life insurance, mental health resources and discounts
- Paid time off, parental and FMLA leave, short- and long-term disability
- Tuition assistance, professional development and continuing education support
Benefits may vary based on the market and employment status
Roper St. Francis Healthcare is an equal opportunity employer.
It is our policy to abide by all Federal and State laws, as well as, the requirements of 41 CFR 60-1.4(a), 60-300.5(a) and 60-741.5(a).Accordingly, all applicants will receive consideration for employment without regard to race, color, national origin, religion, sex, sexual orientation, gender identity, age, genetic information, or protected veteran status, and will not be discriminated against on the basis of disability. If you are an individual with a disability and would like to request a reasonable accommodation as part of the employment selection process, please contact The Talent Acquisition Team at recruitment@RSFH.com
Thank you for considering a career at Roper St. Francis Healthcare!
Shift Schedule
Every other weekend
Delivers patient care utilizing the nursing process through data collection and assessment, identifies and determines the priority of patient’s problems/needs, and evaluates the process and outcome of nursing care; coordinates, provides and directs patient teaching activities and coordinates the care provided by health team members.
Essential Job Functions
In collaboration with the interdisciplinary care team, conducts initial and ongoing patient assessment, analyzes assessment data, creates a plan of care, implements treatment and evaluates treatment effectiveness; administers medications in a safe manner consistent with the State of Practice and organization policies and procedures; serves as point of contact for patients' care coordination throughout hospital departments. Acts as a patient safety advocate by participating in ongoing quality improvement in the department. Incorporates the professional practice model into care delivery
Skills
- Knowledge of contemporary nursing practice and future innovations
- Nursing judgment and skill based on principles of the biological, physical, behavioral, and social sciences
- Application of the nursing process in patient care delivery
- Coordination of patient care delivery
- Evaluation of professional nursing practice to optimize goals and outcomes
- Health teaching and health promotion
- Patient advocacy and partnership
- Interprofessional collaboration and leadership
- Understanding and utilization of office and clinical technologies
- Compassionate, relationship-based approach to help find meaning in illness, suffering, pain, and existence
- Integration of quality improvement, evidence based practices and research in practice
- Accountability for professional actions
- Effective stewardship of available resources
- Conflict management and resilience
- Authority for delegating activities to others, while remaining responsible and accountable for outcomes
Certifications
BLS Basic Life Support, American Heart Association (required at hire for Roper St Francis Healthcare locations; preferred at hire, required prior to independent patient care at BSMH)
Valid nursing license from the state of practice (required)
Education
Associate of Nursing, nursing (required)
OR
Diploma in Nursing (required)
Bachelors of Science, nursing (preferred)
As a Roper St. Francis Healthcare teammate, you're part of a Mission that matters. We support your well-being—personally and professionally. Our benefits are built to grow with you and meet your unique needs, every step of the way.
What we offer
- Competitive pay, incentives, referral bonuses and 403(b) with employer contributions (when eligible)
- Medical, dental, vision, prescription coverage, HSA/FSA options, life insurance, mental health resources and discounts
- Paid time off, parental and FMLA leave, short- and long-term disability
- Tuition assistance, professional development and continuing education support
Benefits may vary based on the market and employment status
Roper St. Francis Healthcare is an equal opportunity employer.
It is our policy to abide by all Federal and State laws, as well as, the requirements of 41 CFR 60-1.4(a), 60-300.5(a) and 60-741.5(a).Accordingly, all applicants will receive consideration for employment without regard to race, color, national origin, religion, sex, sexual orientation, gender identity, age, genetic information, or protected veteran status, and will not be discriminated against on the basis of disability. If you are an individual with a disability and would like to request a reasonable accommodation as part of the employment selection process, please contact The Talent Acquisition Team at recruitment@RSFH.com
See All 62 Registered Nurse Med Surg Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find JobsRegistered Nurse Med Surg Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Registered Nurse Med Surg Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring
- Roper St. Francis Healthcare16
- Prisma Health9
- Bon Secours8
- HCA Healthcare Trident Hospital5
- McLeod Health4
Top Industries Hiring
- Healthcare & Medical Services
- Consulting & Professional Services
What South Carolina Employers Look For
The qualifications that appear most often in registered nurse med surg jobs across South Carolina.
- Active South Carolina RN license or multistate Compact license recognized in South Carolina
- Associate or Bachelor of Science in Nursing degree from an accredited program
- Current BLS certification required, ACLS preferred for higher-acuity assignments
- Minimum one year of med-surg or acute-care clinical experience for most positions
- Demonstrated ability to manage a patient load of four to six on a medical-surgical floor
- Proficiency with electronic health record systems such as Epic or Meditech
Registered Nurse Med Surg Jobs in South Carolina: Frequently Asked Questions
How do you become a registered nurse med surg in South Carolina?
You must hold an active registered nurse license issued by the South Carolina Board of Nursing, which requires completing an accredited ADN or BSN program and passing the NCLEX-RN exam. After licensure, most South Carolina hospitals place new nurses in a med-surg unit as a starting assignment, and many systems offer structured new-graduate residency programs to build clinical confidence before independent patient assignment.
How much do registered nurse med surgs make in South Carolina?
Registered nurse med surgs in South Carolina earn a median of about $82,360 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $66,860 for the lowest 10% to over $106,520 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire registered nurse med surgs in South Carolina?
South Carolina registered nurse med surg roles are posted by Roper St. Francis Healthcare, Prisma Health, and Bon Secours and others right now, based on current listings on Migrate Mate as of August 2026. South Carolina's largest health systems, including those anchored in the Midlands and Lowcountry regions, account for the majority of consistent med-surg postings across the state.
Which South Carolina cities have the most registered nurse med surg jobs?
Charleston, Columbia, and Greenville lead South Carolina for registered nurse med surg openings. Charleston's concentration of MUSC Health campuses and Roper St. Francis facilities drives volume in the Lowcountry, Columbia anchors hiring in the Midlands through Prisma Health and Lexington Medical Center, and Greenville's expanding Bon Secours system fuels demand in the Upstate.
Are there remote registered nurse med surg jobs in South Carolina?
Yes, but they're rare. Bedside med-surg nursing requires hands-on patient care, so fully remote roles are uncommon in this specialty. About 0% of registered nurse med surg openings tied to South Carolina are remote or hybrid as of August 2026, and those positions are typically in utilization review, case management, or telephonic triage rather than direct floor nursing.
How can I get hired as a registered nurse med surg in South Carolina with little or no experience?
The most realistic path is applying to a new-graduate nurse residency program, which Prisma Health, MUSC Health, and Bon Secours Mercy Health all run at their South Carolina facilities for nurses within their first year of licensure. Starting in a patient care technician or nursing assistant role at the same hospital is another common route, as internal candidates with floor familiarity are frequently prioritized when RN positions open on that unit.
Where can I find and apply to registered nurse med surg jobs in South Carolina?
You can find and apply to registered nurse med surg jobs in South Carolina on Migrate Mate, which lists current openings across the state. Search the available roles, identify the ones that fit your experience and preferred location, and apply directly to the positions that match.
See All 62 Registered Nurse Med Surg Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
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