Advanced Practice Provider Jobs in South Carolina
Advanced Practice Provider jobs in South Carolina are concentrated in hospital systems, federally qualified health centers, and outpatient specialty clinics, with demand running from newly credentialed nurse practitioners and physician assistants to experienced clinical leads. The largest hiring activity is in Columbia, Charleston, and Greenville, where anchor employers such as Prisma Health, MUSC Health, and Bon Secours St. Francis maintain deep and ongoing APP pipelines. The most in-demand specialties across the state are primary care, urgent care, and cardiology. Find a role that fits below and apply directly.
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Showing 5 of 27+ Advanced Practice Provider jobs
We’re building a world of health around every individual — shaping a more connected, convenient and compassionate health experience. At CVS Health®, you’ll be surrounded by passionate colleagues who care deeply, innovate with purpose, hold ourselves accountable and prioritize safety and quality in everything we do. Join us and be part of something bigger – helping to simplify health care one person, one family and one community at a time.
Title: Nurse Practitioner, Advanced Practice Provider
Company: Oak Street Health
Location: Greenville - 6119 White Horse Rd #14, Greenville, SC 29611
- Wider range available depending on experience and location
Role Description:
The purpose of a Nurse Practitioner at Oak Street Health is to provide effective and equitable value-based primary care to adults on medicare to keep them happy, healthy, and out of the hospital. Nurse Practitioners see patients independently and collaborate with physicians, depending on the patient’s specific situation. Nurse Practitioners provide longitudinal care and build meaningful patient relationships; this creates trust and helps our patients understand and feel connected to their care plan.
Nurse Practitioners practice in our outpatient practices on a collaborative care team composed of a physician, nurse practitioner or physician assistant, medical assistants, a dedicated medical scribe, and support from registered nurses and care managers. We partner with a network of elite specialists and hospitals for specialty and acute care. As such, our healthcare providers can focus on care within the clinic: primary care, care coordination, and population health.
Core Responsibilities:
- Provision of exceptional primary care.
- Conduct office visits for routine and acute issues.
- Administer Annual wellness visits and health risk assessments, which require a holistic view of health and a focus on thoughtful, accurate, and specific documentation.
- Care coordination with other providers, specialists, testing facilities, and agencies.
- Population health leadership, in coordination with the Care Team (e.g., making sure all eligible females get their evidence-based breast cancer screening every 2 years)
- Assisting the care team with phone triage and outreach.
- Educating patients on their health conditions, care plans, and treatments.
- Participating in Oak Street Health promotional activities.
- Conducting home visits as needed.
- Other duties, as assigned.
This role reports to the Center Medical Director and works closely with operational leadership.
Required Qualifications:
- Master of Science in Nursing, Doctor of Nursing Practice, or NP Certificate Program graduate
-
National certification in at least one of the following specialties:
- Family Nurse Practitioner
- Adult-Gerontology Primary Care Nurse Practitioner
- Adult Nurse Practitioner
- Gerontological Nurse Practitioner
- Active, non-probationary state Nurse Practitioner license
- Active DEA license
- US Work Authorization
Preferred Qualifications:
- Experience in primary care: internal medicine, geriatrics, or family medicine
- Understands HCC (Hierarchical Condition Categories) documentation, ICD-10 (International Classification of Diseases-10) Coding, and Health Risk Assessments (HRAs).
- Passion for teamwork and the opportunity to collaborate cross-functionally
- Desires to be a part of an innovative model focused on empirically-guided population health
- Bilingual proficiency in applicable areas
Anticipated Weekly Hours
40Time Type
Full timePay Range
The typical pay range for this role is:
$78,331.00 - $168,714.00This pay range represents the base hourly rate or base annual full-time salary for all positions in the job grade within which this position falls. The actual base salary offer will depend on a variety of factors including experience, education, geography and other relevant factors.
Our people fuel our future. Our teams reflect the customers, patients, members and communities we serve and we are committed to fostering a workplace where every colleague feels valued and that they belong.
Great benefits for great people
We take pride in offering a comprehensive and competitive mix of pay and benefits that reflects our commitment to our colleagues and their families.
This full‑time position is eligible for a comprehensive benefits package designed to support the physical, emotional, and financial well‑being of colleagues and their families. The benefits for this position include medical, dental, and vision coverage, paid time off, retirement savings options, wellness programs, and other resources, based on eligibility.
Additional details about available benefits are provided during the application process and on Benefits Moments.
We anticipate the application window for this opening will close on: 08/19/2027
Qualified applicants with arrest or conviction records will be considered for employment in accordance with all federal, state and local laws.
We’re building a world of health around every individual — shaping a more connected, convenient and compassionate health experience. At CVS Health®, you’ll be surrounded by passionate colleagues who care deeply, innovate with purpose, hold ourselves accountable and prioritize safety and quality in everything we do. Join us and be part of something bigger – helping to simplify health care one person, one family and one community at a time.
Title: Nurse Practitioner, Advanced Practice Provider
Company: Oak Street Health
Location: Greenville - 6119 White Horse Rd #14, Greenville, SC 29611
- Wider range available depending on experience and location
Role Description:
The purpose of a Nurse Practitioner at Oak Street Health is to provide effective and equitable value-based primary care to adults on medicare to keep them happy, healthy, and out of the hospital. Nurse Practitioners see patients independently and collaborate with physicians, depending on the patient’s specific situation. Nurse Practitioners provide longitudinal care and build meaningful patient relationships; this creates trust and helps our patients understand and feel connected to their care plan.
Nurse Practitioners practice in our outpatient practices on a collaborative care team composed of a physician, nurse practitioner or physician assistant, medical assistants, a dedicated medical scribe, and support from registered nurses and care managers. We partner with a network of elite specialists and hospitals for specialty and acute care. As such, our healthcare providers can focus on care within the clinic: primary care, care coordination, and population health.
Core Responsibilities:
- Provision of exceptional primary care.
- Conduct office visits for routine and acute issues.
- Administer Annual wellness visits and health risk assessments, which require a holistic view of health and a focus on thoughtful, accurate, and specific documentation.
- Care coordination with other providers, specialists, testing facilities, and agencies.
- Population health leadership, in coordination with the Care Team (e.g., making sure all eligible females get their evidence-based breast cancer screening every 2 years)
- Assisting the care team with phone triage and outreach.
- Educating patients on their health conditions, care plans, and treatments.
- Participating in Oak Street Health promotional activities.
- Conducting home visits as needed.
- Other duties, as assigned.
This role reports to the Center Medical Director and works closely with operational leadership.
Required Qualifications:
- Master of Science in Nursing, Doctor of Nursing Practice, or NP Certificate Program graduate
-
National certification in at least one of the following specialties:
- Family Nurse Practitioner
- Adult-Gerontology Primary Care Nurse Practitioner
- Adult Nurse Practitioner
- Gerontological Nurse Practitioner
- Active, non-probationary state Nurse Practitioner license
- Active DEA license
- US Work Authorization
Preferred Qualifications:
- Experience in primary care: internal medicine, geriatrics, or family medicine
- Understands HCC (Hierarchical Condition Categories) documentation, ICD-10 (International Classification of Diseases-10) Coding, and Health Risk Assessments (HRAs).
- Passion for teamwork and the opportunity to collaborate cross-functionally
- Desires to be a part of an innovative model focused on empirically-guided population health
- Bilingual proficiency in applicable areas
Anticipated Weekly Hours
40Time Type
Full timePay Range
The typical pay range for this role is:
$78,331.00 - $168,714.00This pay range represents the base hourly rate or base annual full-time salary for all positions in the job grade within which this position falls. The actual base salary offer will depend on a variety of factors including experience, education, geography and other relevant factors.
Our people fuel our future. Our teams reflect the customers, patients, members and communities we serve and we are committed to fostering a workplace where every colleague feels valued and that they belong.
Great benefits for great people
We take pride in offering a comprehensive and competitive mix of pay and benefits that reflects our commitment to our colleagues and their families.
This full‑time position is eligible for a comprehensive benefits package designed to support the physical, emotional, and financial well‑being of colleagues and their families. The benefits for this position include medical, dental, and vision coverage, paid time off, retirement savings options, wellness programs, and other resources, based on eligibility.
Additional details about available benefits are provided during the application process and on Benefits Moments.
We anticipate the application window for this opening will close on: 08/19/2027
Qualified applicants with arrest or conviction records will be considered for employment in accordance with all federal, state and local laws.
See All 27 Advanced Practice Provider Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find JobsAdvanced Practice Provider Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Advanced Practice Provider Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring
Top Industries Hiring
- Healthcare & Medical Services
- Insurance
What South Carolina Employers Look For
The qualifications that appear most often in advanced practice provider jobs across South Carolina.
- Active South Carolina advanced practice registered nurse license or physician assistant license required
- Master's degree or doctorate in a relevant clinical field from an accredited program
- National board certification such as NCCPA, AANP, or ANCC in applicable specialty
- Current DEA registration and South Carolina prescriptive authority for roles requiring medication management
- Minimum one to three years of clinical experience in a relevant specialty or care setting
- Active BLS certification with ACLS required for acute care and emergency department positions
Advanced Practice Provider Jobs in South Carolina: Frequently Asked Questions
How do you become a advanced practice provider in South Carolina?
To practice as an advanced practice provider in South Carolina, nurse practitioners must obtain licensure through the South Carolina Board of Nursing after completing an accredited graduate-level NP program and passing a national certification exam such as the AANP or ANCC. Physician assistants are licensed through the South Carolina Board of Medical Examiners following graduation from an accredited PA program and passage of the PANCE. Both roles require separate application for prescriptive authority with the appropriate board.
How much do advanced practice providers make in South Carolina?
Advanced practice providers in South Carolina earn a median of about $123,290 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $97,080 for the lowest 10% to over $160,170 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire advanced practice providers in South Carolina?
Companies currently hiring advanced practice providers in South Carolina include CVS Health, Oak Street Health, part of CVS Health, and Prisma Health, per current listings on Migrate Mate as of August 2026. South Carolina's largest health systems, including Prisma Health and MUSC Health, consistently maintain some of the most active APP recruitment pipelines in the state.
Which South Carolina cities have the most advanced practice provider jobs?
Greenville, Myrtle Beach, and Bluffton have the most advanced practice provider openings in South Carolina. Columbia and Charleston lead because they are home to major academic medical centers and large regional health systems, while Greenville's rapid population growth has driven expansion at Prisma Health's Upstate campuses and a growing network of specialty and urgent care practices.
Are there remote advanced practice provider jobs in South Carolina?
Yes, but they're rare. Advanced practice provider work is primarily hands-on and clinic or hospital-based, so fully remote roles represent a small share of total openings. About 14% of advanced practice provider openings tied to South Carolina are remote or hybrid as of August 2026, and those positions are mostly in telehealth primary care, behavioral health consultation, and utilization review rather than direct procedural or acute care roles.
How can I get hired as a advanced practice provider in South Carolina with little or no experience?
The most realistic entry path is applying directly to new-graduate APP residency or fellowship programs, such as those run by MUSC Health and Prisma Health, which are specifically structured for candidates without post-graduate clinical experience. Roles in primary care, urgent care, and retail clinic settings tend to have the lowest experience thresholds and serve as a common first placement for new APPs. Having a South Carolina license in hand before applying and a specialty certification aligned to the posting gives candidates a meaningful edge over unlicensed applicants.
Where can I find and apply to advanced practice provider jobs in South Carolina?
You can find and apply to advanced practice provider jobs in South Carolina on Migrate Mate, which lists current openings across the state. Search the listings for roles that match your specialty, experience level, and preferred location, then apply directly to the ones that fit.
See All 27 Advanced Practice Provider Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
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