Clinical Research Jobs in South Carolina
Clinical research jobs in South Carolina are concentrated in academic medical centers, pharmaceutical contract research, and hospital-based trial units, with demand at every level from entry-level coordinators to principal investigators. The largest hiring activity is in Charleston, Columbia, and Greenville, where institutions like MUSC Health, Prisma Health, and Greenville Health System anchor a steady pipeline of openings. The most in-demand specialties are oncology trials, cardiovascular studies, and regulatory affairs coordination. Scan the live roles below and apply to whichever ones fit.
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Showing 5 of 12+ Clinical Research jobs
The START Center for Cancer Research (“START”) is the world’s largest early phase site network, fully dedicated to oncology clinical research. Throughout our history, START has provided hope to cancer patients in global community practices by offering "Hope Through Access” to cutting edge trials throughout the United States and Europe.
The Clinical Research Coordinator, RN will work under the guidance of senior research staff to support the daily activities of early and late phase oncology and urology clinical trials. The CRC, RN ensures the accurate and timely conduct of clinical research, adhering to protocols, regulatory requirements, and patient safety standards. This role involves direct patient interaction, data collection, and maintaining compliance with Good Clinical Practice (GCP). The Clinical Research Coordinator, RN will be assigned multiple protocols at any time for which they will oversee the aspects of assigned protocols with planning and coordinating patient participation in the trial. Also, this role is responsible for implementation as well as completion of protocol specific requirements, providing accurate, up to date information to all team members involved with any aspect of carrying out protocol specific requirements.
Work Schedule: Monday-Friday 8:00am-5:00pm
Location: 823 82nd Parkway, Suite B, Myrtle Beach, SC, 29572
Essential Responsibilities:
- Communicate on a regular basis with Study Sponsor’s, CRO’s, staff, etc. regarding questions, concerns, as well as status of the protocol.
- Monitor the overall day-to-day conduct of assigned studies in accordance with the specified protocol requirements, Standard Operating Procedures, and Good Clinical Practice to ensure integrity regarding all aspects of the study.
- Create/review forms created or revised for assigned trials to assure protocol compliance.
- Maintain files using standardized study document labeling and filing procedures.
- Implement initial protocol and amendments, training staff who will be involved in patient treatment and management.
- Maintain an up-to-date contact list.
- Assist with patient screening and determination of eligibility.
- Facilitate the informed consent process ensuring that consent is appropriately completed.
- Prepare and manage source documents according to standard operating procedures.
- Recognize deviations to the protocol and will work with leadership and staff to address corrective actions to prevent deviations.
- Assist data coordinator team with case report form completion and query resolution.
- Work with the Principal Investigator to complete and submit Serious Adverse Event reports.
- Perform protocol specific closeout related activities in conjunction with the data coordinator.
- Provide documentation for all deviations whether related to the protocol or a SOP.
- Ensure that all team members involved understand and adhere to assigned protocols.
- Perform telephone triage assessments of patients on trial when necessary.
- Provide patient education regarding participation in a clinical trial, chemotherapy/biotherapy/investigational agent administration and potential side effects.
Required Education and Experience:
Associate’s degree in Nursing.- RN license in state practicing.
- Clinical research experience strongly preferred but not required
- Basic understanding of early and late phase oncology and urology clinical trials
- Strong attention to detail and accuracy in data collection and documentation.
- Ability to manage multiple tasks and meet deadlines in a fast-paced environment.
- Excellent organizational and time-management skills.
- Strong communication skills, both written and verbal.
- Ability to interact professionally with patients, study staff, and external stakeholders.
- Working knowledge of GCP and regulatory requirements.
- Proficient in Microsoft Office Suite and clinical trial management software.
Preferred Education and Experience:
- Bachelor’s degree in Nursing.
- Experience working in an oncology setting.
Physical and Travel Requirements:
- Approximately 80% of time is spent sitting.
- Very fast-paced and ever-changing healthcare environment.
- Demanding deadlines and time frames.
- Constant demand for updating knowledge.
- Works closely with physicians and ancillary personnel in caring for and treating oncology/hematology patients.
Best-in-Class Benefits and Perks
We value the time, talent, and dedication our employees bring to START. Our commitment to your well-being and growth is reflected in a competitive compensation package—based on experience—along with comprehensive benefits designed to support you both personally and professionally:
- 401(k) retirement savings plan with employer match
- Eligibility for an annual performance bonus, based on role and company results
- Generous paid time off and paid holidays
- Comprehensive medical, dental, and vision coverage and optional insurance options
- Company paid life and disability insurance for added financial protection
- Employee Assistance Program (EAP) providing confidential, no ‑cost support for you and your family from day one
- Flexible FSA and HSA plans to support your financial wellness
- Commitment to a supportive environment that values balance, wellbeing, and flexibility
- We’re committed to fostering a collaborative, creative workplace where every team member is encouraged to contribute. At START, you’ll join a team that values continuous learning, professional growth, shared ideas, and a culture built on inclusivity and innovation.
More About START
START clinical trial sites have conducted more than 1,000 early-phase clinical trials, including dozens of therapies that were approved by the FDA or EMA. START represents the world’s largest roster of early-phase principal investigators across its Network of clinical trial sites.
Learn more at STARTresearch.com.
Ready to be part of a team changing the future of cancer treatment?
Join us in our mission to conquer cancer, one clinical trial at a time. Your expertise and dedication can help us bring hope and healing to patients worldwide. Please submit your application online.
We are an equal opportunity employer that welcomes and encourages diversity in the workplace. We do not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law.
The START Center for Cancer Research (“START”) is the world’s largest early phase site network, fully dedicated to oncology clinical research. Throughout our history, START has provided hope to cancer patients in global community practices by offering "Hope Through Access” to cutting edge trials throughout the United States and Europe.
The Clinical Research Coordinator, RN will work under the guidance of senior research staff to support the daily activities of early and late phase oncology and urology clinical trials. The CRC, RN ensures the accurate and timely conduct of clinical research, adhering to protocols, regulatory requirements, and patient safety standards. This role involves direct patient interaction, data collection, and maintaining compliance with Good Clinical Practice (GCP). The Clinical Research Coordinator, RN will be assigned multiple protocols at any time for which they will oversee the aspects of assigned protocols with planning and coordinating patient participation in the trial. Also, this role is responsible for implementation as well as completion of protocol specific requirements, providing accurate, up to date information to all team members involved with any aspect of carrying out protocol specific requirements.
Work Schedule: Monday-Friday 8:00am-5:00pm
Location: 823 82nd Parkway, Suite B, Myrtle Beach, SC, 29572
Essential Responsibilities:
- Communicate on a regular basis with Study Sponsor’s, CRO’s, staff, etc. regarding questions, concerns, as well as status of the protocol.
- Monitor the overall day-to-day conduct of assigned studies in accordance with the specified protocol requirements, Standard Operating Procedures, and Good Clinical Practice to ensure integrity regarding all aspects of the study.
- Create/review forms created or revised for assigned trials to assure protocol compliance.
- Maintain files using standardized study document labeling and filing procedures.
- Implement initial protocol and amendments, training staff who will be involved in patient treatment and management.
- Maintain an up-to-date contact list.
- Assist with patient screening and determination of eligibility.
- Facilitate the informed consent process ensuring that consent is appropriately completed.
- Prepare and manage source documents according to standard operating procedures.
- Recognize deviations to the protocol and will work with leadership and staff to address corrective actions to prevent deviations.
- Assist data coordinator team with case report form completion and query resolution.
- Work with the Principal Investigator to complete and submit Serious Adverse Event reports.
- Perform protocol specific closeout related activities in conjunction with the data coordinator.
- Provide documentation for all deviations whether related to the protocol or a SOP.
- Ensure that all team members involved understand and adhere to assigned protocols.
- Perform telephone triage assessments of patients on trial when necessary.
- Provide patient education regarding participation in a clinical trial, chemotherapy/biotherapy/investigational agent administration and potential side effects.
Required Education and Experience:
Associate’s degree in Nursing.- RN license in state practicing.
- Clinical research experience strongly preferred but not required
- Basic understanding of early and late phase oncology and urology clinical trials
- Strong attention to detail and accuracy in data collection and documentation.
- Ability to manage multiple tasks and meet deadlines in a fast-paced environment.
- Excellent organizational and time-management skills.
- Strong communication skills, both written and verbal.
- Ability to interact professionally with patients, study staff, and external stakeholders.
- Working knowledge of GCP and regulatory requirements.
- Proficient in Microsoft Office Suite and clinical trial management software.
Preferred Education and Experience:
- Bachelor’s degree in Nursing.
- Experience working in an oncology setting.
Physical and Travel Requirements:
- Approximately 80% of time is spent sitting.
- Very fast-paced and ever-changing healthcare environment.
- Demanding deadlines and time frames.
- Constant demand for updating knowledge.
- Works closely with physicians and ancillary personnel in caring for and treating oncology/hematology patients.
Best-in-Class Benefits and Perks
We value the time, talent, and dedication our employees bring to START. Our commitment to your well-being and growth is reflected in a competitive compensation package—based on experience—along with comprehensive benefits designed to support you both personally and professionally:
- 401(k) retirement savings plan with employer match
- Eligibility for an annual performance bonus, based on role and company results
- Generous paid time off and paid holidays
- Comprehensive medical, dental, and vision coverage and optional insurance options
- Company paid life and disability insurance for added financial protection
- Employee Assistance Program (EAP) providing confidential, no ‑cost support for you and your family from day one
- Flexible FSA and HSA plans to support your financial wellness
- Commitment to a supportive environment that values balance, wellbeing, and flexibility
- We’re committed to fostering a collaborative, creative workplace where every team member is encouraged to contribute. At START, you’ll join a team that values continuous learning, professional growth, shared ideas, and a culture built on inclusivity and innovation.
More About START
START clinical trial sites have conducted more than 1,000 early-phase clinical trials, including dozens of therapies that were approved by the FDA or EMA. START represents the world’s largest roster of early-phase principal investigators across its Network of clinical trial sites.
Learn more at STARTresearch.com.
Ready to be part of a team changing the future of cancer treatment?
Join us in our mission to conquer cancer, one clinical trial at a time. Your expertise and dedication can help us bring hope and healing to patients worldwide. Please submit your application online.
We are an equal opportunity employer that welcomes and encourages diversity in the workplace. We do not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law.
See All 12 Clinical Research Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find Clinical Research JobsClinical Research Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Clinical Research Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring
What South Carolina Employers Look For
The qualifications that appear most often in clinical research jobs across South Carolina.
- Relevant clinical research certification such as ACRP CCRC or SOCRA CCRP preferred or required
- Bachelor's degree in life sciences, nursing, pharmacy, or a related health discipline
- Minimum one to two years of direct clinical trial coordination or research experience
- Demonstrated knowledge of GCP guidelines, FDA regulations, and IRB submission processes
- Experience with electronic data capture systems such as Medidata Rave or REDCap
- Strong written communication skills for protocol documentation, adverse event reporting, and sponsor correspondence
Clinical Research Jobs in South Carolina: Frequently Asked Questions
How do you become a clinical research in South Carolina?
South Carolina does not require a state-issued license to work as a clinical research coordinator, so the path runs through education and nationally recognized certification. Most positions require at least a bachelor's degree in a life sciences or health-related field. From there, earning the ACRP Certified Clinical Research Coordinator credential or the SOCRA CCRP designation strengthens candidacy significantly. Many South Carolina academic medical centers, including MUSC Health and Prisma Health, post entry-level coordinator roles that serve as the standard starting point.
Which companies hire clinical researchs in South Carolina?
Employers hiring clinical researchs in South Carolina right now include Tribe Clinical Research, The START Center for Cancer Research, and Prisma Health, based on current listings on Migrate Mate as of October 2026. South Carolina's academic medical centers and contract research organizations tied to the state's pharmaceutical and biotech activity in the Charleston and Columbia corridors tend to post the most consistent volume.
Which South Carolina cities have the most clinical research jobs?
Charleston, Greenville, and Myrtle Beach have the most clinical research openings in South Carolina. Charleston leads because MUSC Health operates one of the Southeast's largest academic research programs, while Columbia's concentration of Prisma Health facilities and the University of South Carolina drives strong trial activity, and Greenville's growth as a regional medical hub has brought increasing research infrastructure to the Upstate.
Are there remote clinical research jobs in South Carolina?
Yes, but they're limited. About 100% of clinical research openings tied to South Carolina are remote or hybrid as of October 2026, reflecting the hands-on nature of most trial work. The roles most likely to offer remote or hybrid arrangements are regulatory affairs positions, data management roles, and sponsor-side monitoring jobs that do not require direct patient contact or on-site protocol execution.
How can I get hired as a clinical research in South Carolina with little or no experience?
The most realistic entry path is applying for a clinical research coordinator I or research assistant role at one of South Carolina's academic medical centers, which regularly hire candidates with a relevant bachelor's degree and no prior trial experience. MUSC Health and Prisma Health both run research departments that onboard new coordinators and provide GCP training internally. Candidates coming from adjacent roles such as medical assistant, phlebotomist, or clinical data specialist have a strong lateral case, and completing the ACRP Essentials certificate before applying gives an additional edge.
Where can I find and apply to clinical research jobs in South Carolina?
You can find and apply to clinical research jobs in South Carolina on Migrate Mate, which lists current openings from employers actively hiring in the state. Search the listings, identify the roles that match your experience and target area, and apply directly to the ones that fit.
See All 12 Clinical Research Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find Clinical Research Jobs