Pediatric Registered Nurse Jobs in South Carolina
Pediatric Registered Nurse jobs in South Carolina are consistently active, with demand concentrated in children's hospital units, pediatric outpatient clinics, and large academic health systems serving families statewide. The heaviest hiring is in Columbia, Charleston, and Greenville, where employers like MUSC Health, Prisma Health, and Spartanburg Regional Healthcare System maintain pediatric programs across multiple care settings. The most in-demand specialties are pediatric emergency nursing, neonatal intensive care, and pediatric oncology. See the openings below and apply to the ones that match your experience.
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- One-on-one, patient-centered pediatric care
- Flexible scheduling (full-time, part-time, PRN)
- Days, nights, and weekend shifts available
- 24/7 clinical and operational support
- Paid training, simulation lab experiences, and continuing education
- Weekly pay and reliable scheduling
- Supportive, mission-driven team culture
- Opportunities for career growth and advancement
What You’ll Do
- Provide skilled nursing care in a home health setting
- Perform ongoing patient assessments and clinical evaluations
- Administer prescribed medications, treatments, and therapies
- Deliver care in accordance with physician orders and plan of care
- Coordinate care with families, providers, and care teams
- Educate patients and family members to support improved outcomes
- Implement preventive measures to ensure patient safety and quality care
- Respond appropriately to changes in patient condition
Qualifications
- Active, unrestricted Registered Nurse (RN) or Licensed Practical Nurse (LPN) license (South Carolina)
- License acquired 1 year prior to application
- Ability to provide care in a home setting
- Strong communication and clinical decision-making skills
- Pediatric or home health experience
- Experience with high-acuity skills (trach, vent, G-tube)
Schedule & Flexibility
- Full-time, part-time, and PRN opportunities
- Flexible scheduling based on your availability
- 8, 10, 12, or 16-hour shifts available
- Major medical, dental, & vision plans with a generous portion of medical covered by AOC
- Group & voluntary life insurance
- 401K
- Paid time off
- Employee Assistance Program
- Supplemental Insurance Policies
- Patient Care Coordination Services
- Prescription Concierge Service
- Anytime Fitness gym discount
- Voluntary long-term & short-term disability
- Free life insurance
- Cellular discounts
- Health savings account
- Dependent care flexible spending account
- Wellness program & incentives
- Legal Shield & Identity Shield
- Flexible Spending Accounts (FSA)
- Annual car giveaway
- and many more!
Our Mission
- Heart – Patients come first in everything we do
- Advocacy – We champion our clients, clinicians, and industry
- Love – We care deeply about our employees and families
- Outreach – We engage and give back to our communities
- Speed – We act quickly to meet the needs of our patients
U.S. Equal Employment Opportunity/Affirmative Action Information
See All 35 Pediatric Registered Nurse Jobs in South Carolina
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Find JobsPediatric Registered Nurse Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Pediatric Registered Nurse Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring
- Angels of Care Pediatric Home Health12

- BAYADA Home Health Care10

- Prisma Health5

- Atrium Health1

Top Industries Hiring
- Healthcare & Medical Services
What South Carolina Employers Look For
The qualifications that appear most often in pediatric registered nurse jobs across South Carolina.
- Active South Carolina RN license or multistate Compact license recognized in South Carolina
- Current BLS certification required, with PALS certification strongly preferred
- Associate or Bachelor of Science in Nursing degree from an accredited program
- Minimum one to two years of experience in a pediatric inpatient or outpatient setting
- Demonstrated proficiency in pediatric assessment, IV placement, and age-appropriate patient education
- Strong communication and family-centered care skills across diverse pediatric populations
Pediatric Registered Nurse Jobs in South Carolina: Frequently Asked Questions
How do you become a pediatric registered nurse in South Carolina?
You become a pediatric registered nurse in South Carolina by earning an Associate or Bachelor of Science in Nursing, passing the NCLEX-RN, and obtaining an active RN license through the South Carolina Board of Nursing. South Carolina participates in the Nurse Licensure Compact, so nurses licensed in other Compact states can practice in South Carolina without a separate license. After licensure, most pediatric RN roles require hands-on clinical experience in a pediatric setting, and many nurses pursue Certified Pediatric Nurse credentialing to strengthen their candidacy.
How much do pediatric registered nurses make in South Carolina?
Pediatric registered nurses in South Carolina earn a median of about $82,360 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $66,860 for the lowest 10% to over $106,520 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire pediatric registered nurses in South Carolina?
Employers hiring pediatric registered nurses in South Carolina right now include Angels of Care Pediatric Home Health, BAYADA Home Health Care, and Prisma Health, based on current listings on Migrate Mate as of August 2026. South Carolina's larger academic and regional health systems tend to post the most consistent pediatric RN openings across inpatient, outpatient, and specialty care settings.
Which South Carolina cities have the most pediatric registered nurse jobs?
Columbia, Greenville, and Fort Mill have the most pediatric registered nurse openings in South Carolina. Columbia and Charleston anchor the highest volume of listings because they are home to major academic medical centers and children's specialty programs, while Greenville's growth as an Upstate economic hub has expanded Prisma Health's pediatric services, making it a consistently strong market for pediatric nursing candidates.
Are there remote pediatric registered nurse jobs in South Carolina?
Yes, but they're rare. Pediatric nursing is fundamentally a hands-on clinical role, so the large majority of positions require on-site presence in a hospital, clinic, or outpatient facility. About 17% of pediatric registered nurse openings tied to South Carolina are remote or hybrid as of August 2026, and those positions tend to fall in pediatric telephone triage, care coordination, or utilization review rather than direct bedside care.
How can I get hired as a pediatric registered nurse in South Carolina with little or no experience?
The most realistic entry path is a new graduate RN residency program, and several large South Carolina health systems run structured ones. MUSC Health and Prisma Health both offer nurse residency programs that include pediatric rotations and are specifically designed to bring newly licensed RNs into clinical practice. Candidates with pediatric clinical hours from nursing school, a PALS certification, or experience in adjacent roles such as pediatric medical assistant or pediatric patient care technician have a measurable advantage when competing for these positions.
Where can I find and apply to pediatric registered nurse jobs in South Carolina?
You can find and apply to pediatric registered nurse jobs in South Carolina on Migrate Mate, which lists current openings from employers actively hiring in the state. Search the listings to find roles that match your experience, specialty, and preferred location within South Carolina, then apply directly to the ones that fit.
See All 35 Pediatric Registered Nurse Jobs in South Carolina
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