Pediatric Registered Nurse Jobs in South Carolina

Pediatric Registered Nurse jobs in South Carolina are consistently active, with demand concentrated in children's hospital units, pediatric outpatient clinics, and large academic health systems serving families statewide. The heaviest hiring is in Columbia, Charleston, and Greenville, where employers like MUSC Health, Prisma Health, and Spartanburg Regional Healthcare System maintain pediatric programs across multiple care settings. The most in-demand specialties are pediatric emergency nursing, neonatal intensive care, and pediatric oncology. See the openings below and apply to the ones that match your experience.

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Overview

Open roles35
Top employerAngels of Care Pediatric Home Health
Top cityColumbia, SC
Cities hiring21
Work type83% On-site
Top industryHealthcare

Showing 5 of 35+ Pediatric Registered Nurse jobs

Angels of Care Pediatric Home Health
Licensed Practical Nurse (LPN) / Registered Nurse (RN) – Pediatric Home Health
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Angels of Care Pediatric Home Health
Added 1d ago
Licensed Practical Nurse (LPN) / Registered Nurse (RN) – Pediatric Home Health
Angels of Care Pediatric Home Health
Summerville, South Carolina
Healthcare Administration
Nursing
Patient Services & Wellbeing
1,001-5,000

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Spartanburg Regional Healthcare System
Registered Nurse (RN) - Pediatric ICU (PICU)
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Spartanburg Regional Healthcare System
Added 1d ago
Registered Nurse (RN) - Pediatric ICU (PICU)
Spartanburg Regional Healthcare System
Spartanburg, South Carolina
Healthcare Administration
Nursing
Patient Services & Wellbeing

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Mount Pleasant Pediatrics
Pediatric Nurse LPN RN
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Mount Pleasant Pediatrics
Added 1d ago
Pediatric Nurse LPN RN
Mount Pleasant Pediatrics
Mount Pleasant, South Carolina
Healthcare Administration
Nursing
Patient Services & Wellbeing
$25 - $28/hr
On-Site

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Advocate Aurora Health
RN Levine Children's Pediatric Outpatient- Evenings/Weekends-Fort Mill Full Time Hybrid
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Advocate Aurora Health
Added 2d ago
RN Levine Children's Pediatric Outpatient- Evenings/Weekends-Fort Mill Full Time Hybrid
Advocate Aurora Health
Fort Mill, South Carolina
Healthcare Administration
Nursing
Patient Services & Wellbeing
$35.5 - $53.25/hr
Hybrid
BLS Certification
10,000+

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Prisma Health
Registered Nurse (RN)-Acute Care, Pediatric ICU, FT, Night
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Prisma Health
Added 2d ago
Registered Nurse (RN)-Acute Care, Pediatric ICU, FT, Night
Prisma Health
Greenville, South Carolina
Business Operations
Compliance & Legal
Compliance & Risk
Nursing Diploma
10,000+

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Pediatric Registered Nurse Jobs by City in South Carolina

Where South Carolina roles are concentrated, by current openings.

Columbia
5 jobs
Greenville
5 jobs
Fort Mill
4 jobs
Charleston
2 jobs
Summerville
2 jobs
Mount Pleasant
2 jobs
Easley
1 job
Clinton
1 job
Gaffney
1 job

Pediatric Registered Nurse Job Market in South Carolina

A snapshot from current South Carolina openings, updated as new roles post.

Who's Hiring

  • Angels of Care Pediatric Home Health
    Angels of Care Pediatric Home Health12
  • BAYADA Home Health Care
    BAYADA Home Health Care10
  • Prisma Health
    Prisma Health5
  • Atrium Health
    Atrium Health1

Top Industries Hiring

  • Healthcare & Medical Services

What South Carolina Employers Look For

The qualifications that appear most often in pediatric registered nurse jobs across South Carolina.

  • Active South Carolina RN license or multistate Compact license recognized in South Carolina
  • Current BLS certification required, with PALS certification strongly preferred
  • Associate or Bachelor of Science in Nursing degree from an accredited program
  • Minimum one to two years of experience in a pediatric inpatient or outpatient setting
  • Demonstrated proficiency in pediatric assessment, IV placement, and age-appropriate patient education
  • Strong communication and family-centered care skills across diverse pediatric populations

Pediatric Registered Nurse Jobs in South Carolina: Frequently Asked Questions

How do you become a pediatric registered nurse in South Carolina?

You become a pediatric registered nurse in South Carolina by earning an Associate or Bachelor of Science in Nursing, passing the NCLEX-RN, and obtaining an active RN license through the South Carolina Board of Nursing. South Carolina participates in the Nurse Licensure Compact, so nurses licensed in other Compact states can practice in South Carolina without a separate license. After licensure, most pediatric RN roles require hands-on clinical experience in a pediatric setting, and many nurses pursue Certified Pediatric Nurse credentialing to strengthen their candidacy.

How much do pediatric registered nurses make in South Carolina?

Pediatric registered nurses in South Carolina earn a median of about $82,360 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $66,860 for the lowest 10% to over $106,520 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire pediatric registered nurses in South Carolina?

Employers hiring pediatric registered nurses in South Carolina right now include Angels of Care Pediatric Home Health, BAYADA Home Health Care, and Prisma Health, based on current listings on Migrate Mate as of August 2026. South Carolina's larger academic and regional health systems tend to post the most consistent pediatric RN openings across inpatient, outpatient, and specialty care settings.

Which South Carolina cities have the most pediatric registered nurse jobs?

Columbia, Greenville, and Fort Mill have the most pediatric registered nurse openings in South Carolina. Columbia and Charleston anchor the highest volume of listings because they are home to major academic medical centers and children's specialty programs, while Greenville's growth as an Upstate economic hub has expanded Prisma Health's pediatric services, making it a consistently strong market for pediatric nursing candidates.

Are there remote pediatric registered nurse jobs in South Carolina?

Yes, but they're rare. Pediatric nursing is fundamentally a hands-on clinical role, so the large majority of positions require on-site presence in a hospital, clinic, or outpatient facility. About 17% of pediatric registered nurse openings tied to South Carolina are remote or hybrid as of August 2026, and those positions tend to fall in pediatric telephone triage, care coordination, or utilization review rather than direct bedside care.

How can I get hired as a pediatric registered nurse in South Carolina with little or no experience?

The most realistic entry path is a new graduate RN residency program, and several large South Carolina health systems run structured ones. MUSC Health and Prisma Health both offer nurse residency programs that include pediatric rotations and are specifically designed to bring newly licensed RNs into clinical practice. Candidates with pediatric clinical hours from nursing school, a PALS certification, or experience in adjacent roles such as pediatric medical assistant or pediatric patient care technician have a measurable advantage when competing for these positions.

Where can I find and apply to pediatric registered nurse jobs in South Carolina?

You can find and apply to pediatric registered nurse jobs in South Carolina on Migrate Mate, which lists current openings from employers actively hiring in the state. Search the listings to find roles that match your experience, specialty, and preferred location within South Carolina, then apply directly to the ones that fit.

See All 35 Pediatric Registered Nurse Jobs in South Carolina

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