Mental Health Jobs in South Carolina
Mental Health jobs in South Carolina are open across Greenville, Columbia, and Charleston and other South Carolina metros, with employers like Prisma Health, Medical University of South Carolina, and LifeStance Health hiring at every experience level. Find a role that fits below and apply directly.
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Inspire health. Serve with compassion. Be the difference.
Job Summary
Performs direct patient care duties as assigned or delegated by the Charge Nurse to meet the physical, social, emotional, and behavioral needs of the psychiatric and/or chemically dependent patient. Delivers care to patients (voluntary and involuntary) of all ages and demonstrates knowledge of population-specific developmental tasks gained through training and experience. As delegated, performs basic nursing activities and additional clinical responsibilities as appropriate and necessary for patient population served.
Essential Functions
- All team members are expected to be knowledgeable and compliant with Prisma Health's purpose: Inspire health. Serve with compassion. Be the difference.
- Attends to mentally ill and/or chemically dependent patients with active and reflective listening, demonstrating a caring and therapeutic manner. Provides individualized care to both voluntary and involuntary patients in a manner that considers age-appropriateness, safety, comfort, and the therapeutic environment. Interacts and assesses assigned patients for level of functioning and mental status.
- Observes, collects, and communicates relevant patient information and communicates this verbally and via the medical record to other treatment team members. Provides timely documentation in the medical record on assigned patients in legible, accurate and appropriate format following hospital and unit procedures.
- Monitors patients' level of distress, anxiety, and/or agitation to reduce or prevent incidents. Responds to patient crisis and/or codes via utilization of de-escalation and de-stimulation techniques. Has routine encounters/interactions with patients that are in crisis or at high risk for self-harm or other destructive behavior.
- Attends and/or facilitates therapeutic groups and psycho-educational programs. Utilizes a variety of psycho-therapeutic techniques, demonstrating knowledge of mental health principles and practices.
- Upholds patient confidentiality at all times, using exceptional judgment to ensure patient privacy and dignity.
- Establishes positive relationships with team members and practices effective communication. Is aware of own communication style and stress response. Provides excellent customer service to patients, physicians, and other staff members by responding promptly and appropriately to inquiries and requests.
- Participates in the development, implementation, and evaluation of patient treatment programs. Provides input and suggestions for improvement in unit and facility processes. Maintains established departmental policies and procedures, objectives, quality assurance program, safety, environmental and infection control standards.
- Informs Charge Nurse or direct supervisor of any activities, issues, concerns that may impact patient safety or the therapeutic milieu.
- Collects and documents vital signs, weighs patients, and collects routine urine specimens, clean catch urine specimens, stool specimens, and sputum specimens, and other duties as assigned or requested. Performs point of care testing as trained and delegated by RN. Properly documents and maintains data on medical record and informs RN of activities performed.
- Attends staff meetings regularly, participates in annual in-services and mandatory educational experiences. Keeps abreast of current psychiatric issues and methods.
- Performs other duties as assigned.
Supervisory/Management Responsibilities
- This is a non-management job that will report to a supervisor, manager, director or executive.
Minimum Requirements
- Education - High School diploma or equivalent or post-secondary degree in a related field of study.
- Experience - No previous experience. Acute Inpatient Hospital Care or Long-Term Care experience - Preferred
In Lieu Of
- NA
Required Certifications, Registrations, Licenses
- NA
Knowledge, Skills and Abilities
- NA
Work Shift
Variable (United States of America)
Location
Marshall Pickens Hospital
Facility
1007 Marshall I Pickens Hospital
Department
10076104 Nursing Service Unit A
Share your talent with us! Our vision is simple: to transform healthcare for the benefits of the communities we serve. The transformation of healthcare requires talented individuals in every role here at Prisma Health.
See All 177+ Mental Health Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find Mental Health JobsMental Health Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Mental Health Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring
- Prisma Health42

- Medical University of South Carolina35

- LifeStance Health29

- Aspen Dental26

- Self Regional Healthcare12

Top Industries Hiring
- Healthcare & Medical Services148
- Education23
- Consulting & Professional Services18
- Insurance3
- Agriculture & Farming2
What South Carolina Employers Look For
The qualifications that appear most often in mental health jobs across South Carolina.
- Master's degree in counseling, social work, psychology, or a related clinical field
- Active state licensure such as LCSW, LPC, LMFT, or equivalent credential
- Experience conducting individual, group, or family therapy sessions
- Proficiency with electronic health record systems for documentation and treatment planning
- Knowledge of evidence-based modalities such as CBT, DBT, or trauma-informed care
- Ability to complete clinical assessments, crisis evaluations, and progress notes on deadline
Mental Health Jobs in South Carolina: Frequently Asked Questions
How many mental health jobs are there in South Carolina?
There are 177+ mental health openings in South Carolina on Migrate Mate as of June 2026, with the most roles in Greenville, Columbia, and Charleston. New positions post regularly as employers across South Carolina hire.
Which South Carolina cities have the most mental health jobs?
Greenville, Columbia, and Charleston have the most mental health openings in South Carolina right now, with additional roles spread across smaller metros statewide.
Which companies hire mental healths in South Carolina?
Employers hiring mental healths in South Carolina include Prisma Health, Medical University of South Carolina, and LifeStance Health, based on current listings on Migrate Mate as of June 2026.
Are there remote mental health jobs in South Carolina?
Yes. About 17% of mental health openings tied to South Carolina are remote or hybrid as of June 2026. The rest are on-site roles based in South Carolina metros.
How do I apply for mental health jobs in South Carolina?
You can apply to mental health jobs in South Carolina directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred South Carolina location, then apply to each one that fits.
See All 177+ Mental Health Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find Mental Health Jobs