Dental Assistant Jobs in South Carolina

Dental assistant jobs in South Carolina are concentrated in private dental practices, community health centers, and multi-specialty group practices, with steady demand from entry-level chair-side roles through experienced expanded-duty positions. The busiest hiring markets are Columbia, Greenville, and Charleston, where established groups such as Prisma Health, Greenville Health System, and Aspen Dental maintain active rosters across multiple locations. Expanded-duty dental assisting and orthodontic assisting are the most in-demand specialties statewide. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles50
Top employerHeartland Dental
Top cityColumbia, SC
Cities hiring27
Work type100% On-site
Top industryHealthcare

Showing 5 of 50+ Dental Assistant jobs

PDS Health
Registered Dental Assistant
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PDS Health
New 3h ago
Registered Dental Assistant
PDS Health
Indian Land, South Carolina
Business Operations
Compliance & Legal
Compliance & Risk
$20 - $27.75/hr
Coronal Polish Certificate
5,001-10,000

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Heartland Dental
Dental Assistant
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Heartland Dental
New 9h ago
Dental Assistant
Heartland Dental
Boiling Springs, South Carolina
Customer Service
Customer Support
Hospitality & Guest Services
X-Ray Certification
10,000+

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Aspen Dental
Dental Assistant - Entry Level
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Aspen Dental
New 16h ago
Dental Assistant - Entry Level
Aspen Dental
Easley, South Carolina
Customer Service
Customer Support
Hospitality & Guest Services
$17 - $20/hr
High school diploma or GED
10,000+

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Aspen Dental
Dental Assistant
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Aspen Dental
New 16h ago
Dental Assistant
Aspen Dental
Summerville, South Carolina
Customer Service
Customer Support
Hospitality & Guest Services
$18 - $21/hr
High school diploma or GED
10,000+

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Premise Health
Dental Assistant
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Premise Health
Added 1d ago
Dental Assistant
Premise Health
Greer, South Carolina
Healthcare Administration
Medical Assistant
Patient Services & Wellbeing
CPR Certification
5,001-10,000

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See All 50 Dental Assistant Jobs in South Carolina

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Dental Assistant Jobs by City in South Carolina

Where South Carolina roles are concentrated, by current openings.

Columbia
9 jobs
Charleston
3 jobs
Spartanburg
3 jobs
Summerville
3 jobs
Myrtle Beach
3 jobs
Bluffton
2 jobs
Fort Mill
2 jobs
Lexington
2 jobs
Greenville
2 jobs

Dental Assistant Job Market in South Carolina

A snapshot from current South Carolina openings, updated as new roles post.

Who's Hiring

  • Heartland Dental
    Heartland Dental13
  • Aspen Dental
    Aspen Dental7
  • PDS Health
    PDS Health4
  • Lone Peak Dental
    Lone Peak Dental3
  • D4C Dental Brands
    D4C Dental Brands3

Top Industries Hiring

  • Healthcare & Medical Services

What South Carolina Employers Look For

The qualifications that appear most often in dental assistant jobs across South Carolina.

  • Active South Carolina dental assistant registration or exemption status as required by the State Board of Dentistry
  • Completion of an accredited dental assisting program or equivalent on-the-job training hours
  • Current radiography certification to take and process dental X-rays independently
  • CPR and basic life support certification maintained at the time of hire
  • Experience with dental practice management software such as Dentrix or Eaglesoft
  • Strong chairside assisting skills including four-handed dentistry and instrument sterilization

Dental Assistant Jobs in South Carolina: Frequently Asked Questions

How do you become a dental assistant in South Carolina?

South Carolina dental assistants who perform certain clinical functions, including coronal polishing and sealant placement, must register with the South Carolina Board of Dentistry after completing an approved training program and meeting the board's competency requirements. General chairside assistants without expanded duties may work without state registration, but most employers prefer or require completion of an accredited dental assisting program. Radiography certification is a near-universal hiring requirement across the state.

Which companies hire dental assistants in South Carolina?

Employers hiring dental assistants in South Carolina right now include Heartland Dental, Aspen Dental, and PDS Health, based on current listings on Migrate Mate as of August 2026. South Carolina's mix of large health system-affiliated dental clinics and independently owned multi-location group practices means openings appear regularly across both corporate and community-focused settings statewide.

Which South Carolina cities have the most dental assistant jobs?

The South Carolina cities with the most dental assistant openings are Columbia, Charleston, and Spartanburg. Columbia leads as the state capital and home to major health systems, Greenville draws volume from its fast-growing Upstate corridor anchored by large group practices and hospital-affiliated clinics, and Charleston's expanding coastal population supports a dense concentration of private practices and specialty offices.

Are there remote dental assistant jobs in South Carolina?

Yes, but they're rare. About 0% of dental assistant openings tied to South Carolina are remote or hybrid as of August 2026, reflecting that most duties require direct patient contact and in-office equipment. The small share of remote work in this field typically involves dental insurance coordination, treatment plan consulting, or administrative support roles attached to larger group practices.

How can I get hired as a dental assistant in South Carolina with little or no experience?

The most realistic entry path is enrolling in an accredited dental assisting program at a South Carolina technical college, such as Midlands Technical College or Trident Technical College, which combine hands-on clinical hours with classroom instruction and often connect graduates directly to local practices. Community health centers affiliated with Federally Qualified Health Centers across the state frequently hire new graduates for entry-level chairside roles. Completing radiography certification before applying gives candidates a measurable edge over others without clinical credentials.

Where can I find and apply to dental assistant jobs in South Carolina?

You can find and apply to dental assistant jobs in South Carolina on Migrate Mate, which lists current openings across the state. Search the available roles, find the ones that match your experience and location, and apply directly to the employers that interest you.

See All 50 Dental Assistant Jobs in South Carolina

Find roles in South Carolina that match your experience and apply in just a few clicks.

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