Dental Assistant Jobs in South Carolina
Dental assistant jobs in South Carolina are concentrated in private dental practices, community health centers, and multi-specialty group practices, with steady demand from entry-level chair-side roles through experienced expanded-duty positions. The busiest hiring markets are Columbia, Greenville, and Charleston, where established groups such as Prisma Health, Greenville Health System, and Aspen Dental maintain active rosters across multiple locations. Expanded-duty dental assisting and orthodontic assisting are the most in-demand specialties statewide. Scan the live roles below and apply to whichever ones fit.
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- Perform functions in accordance with the applicable state’s Dental Auxiliaries Table of Permitted Duties and actively participate in attempting to achieve the Perfect Patient Experience® by striving to keep your patients focused on the best possible treatment with urgency
- Attend to the patient’s individual concerns and expectations.
- Maintain a clean, sterile, and cheerful environment where your patients feel comfortable; prepare patients for treatment, and assist the doctors - thereby enabling them to provide efficient, quality dental treatment
- At the direction of the dentist, obtain dental history and/or records from patient (review patient health history and careslips), complete x-rays and intra-oral pictures of patients as appropriate, instruct patients on postoperative and general oral health care, and record patient charting and all doctor notes on treatment record
- Prepare tray setups for dental procedures, present instruments and materials to dentists and keep patients' mouths dry and clear by using suction or other devices and sterilize and disinfect instruments, equipment, and operatories in accordance with the American Dental Association guidelines
- Escort patients to/from the front desk and introduce them to the Continuing Care Clerk
- Maintain adequate supply levels in each operatory, replenishing as needed, an appropriate professional appearance and demeanor in accordance with Company policy, strict compliance with State, Federal, and other regulations, (e.g., OSHA, WC, Dental Board, HIPAA, ADA, FEHA, DOL, HR policies and practices)
- Equivalent to high school diploma or general education degree (GED), and specified training courses as mandated by state for certification, licensure, or registrationrequired
- Associate degree or one-year certificate from an accredited college or technical school, or equivalent combination of education and experience preferred
- Certificates, Licenses and registrations as mandated by applicable state (e.g. coronal polish, x-ray exposure, ultrasonic scaling for orthodontic procedures, pit and fissure sealant application, etc.)
- While performing the duties of this job, the employee is regularly required to use hands to finger, handle, or feel; reach with hands and arms; talk, hear, and smell. The employee is frequently required to stand, walk, and sit. The employee is occasionally required to stoop, kneel, or crouch. The employee must frequently lift and/or move up to 10 pounds. Specific vision abilities required by this job include close vision, peripheral vision, and depth perception. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
- Medical, dental and vision insurance
- Paid time off
- Tuition Reimbursement
- Child care assistance
- 401K
- Paid time to volunteer in your local community
- Shift premium pay for eligible roles who work weekends
See All 50 Dental Assistant Jobs in South Carolina
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Find Dental Assistant JobsDental Assistant Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Dental Assistant Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring
- Heartland Dental13

- Aspen Dental7

- PDS Health4

- Lone Peak Dental3

- D4C Dental Brands3

Top Industries Hiring
- Healthcare & Medical Services
What South Carolina Employers Look For
The qualifications that appear most often in dental assistant jobs across South Carolina.
- Active South Carolina dental assistant registration or exemption status as required by the State Board of Dentistry
- Completion of an accredited dental assisting program or equivalent on-the-job training hours
- Current radiography certification to take and process dental X-rays independently
- CPR and basic life support certification maintained at the time of hire
- Experience with dental practice management software such as Dentrix or Eaglesoft
- Strong chairside assisting skills including four-handed dentistry and instrument sterilization
Dental Assistant Jobs in South Carolina: Frequently Asked Questions
How do you become a dental assistant in South Carolina?
South Carolina dental assistants who perform certain clinical functions, including coronal polishing and sealant placement, must register with the South Carolina Board of Dentistry after completing an approved training program and meeting the board's competency requirements. General chairside assistants without expanded duties may work without state registration, but most employers prefer or require completion of an accredited dental assisting program. Radiography certification is a near-universal hiring requirement across the state.
Which companies hire dental assistants in South Carolina?
Employers hiring dental assistants in South Carolina right now include Heartland Dental, Aspen Dental, and PDS Health, based on current listings on Migrate Mate as of August 2026. South Carolina's mix of large health system-affiliated dental clinics and independently owned multi-location group practices means openings appear regularly across both corporate and community-focused settings statewide.
Which South Carolina cities have the most dental assistant jobs?
The South Carolina cities with the most dental assistant openings are Columbia, Charleston, and Spartanburg. Columbia leads as the state capital and home to major health systems, Greenville draws volume from its fast-growing Upstate corridor anchored by large group practices and hospital-affiliated clinics, and Charleston's expanding coastal population supports a dense concentration of private practices and specialty offices.
Are there remote dental assistant jobs in South Carolina?
Yes, but they're rare. About 0% of dental assistant openings tied to South Carolina are remote or hybrid as of August 2026, reflecting that most duties require direct patient contact and in-office equipment. The small share of remote work in this field typically involves dental insurance coordination, treatment plan consulting, or administrative support roles attached to larger group practices.
How can I get hired as a dental assistant in South Carolina with little or no experience?
The most realistic entry path is enrolling in an accredited dental assisting program at a South Carolina technical college, such as Midlands Technical College or Trident Technical College, which combine hands-on clinical hours with classroom instruction and often connect graduates directly to local practices. Community health centers affiliated with Federally Qualified Health Centers across the state frequently hire new graduates for entry-level chairside roles. Completing radiography certification before applying gives candidates a measurable edge over others without clinical credentials.
Where can I find and apply to dental assistant jobs in South Carolina?
You can find and apply to dental assistant jobs in South Carolina on Migrate Mate, which lists current openings across the state. Search the available roles, find the ones that match your experience and location, and apply directly to the employers that interest you.
See All 50 Dental Assistant Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
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