Dental Assistant Jobs in South Carolina

Dental assistant jobs in South Carolina are concentrated in private dental practices, community health centers, and multi-specialty group practices, with steady demand from entry-level chair-side roles through experienced expanded-duty positions. The busiest hiring markets are Columbia, Greenville, and Charleston, where established groups such as Prisma Health, Greenville Health System, and Aspen Dental maintain active rosters across multiple locations. Expanded-duty dental assisting and orthodontic assisting are the most in-demand specialties statewide. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles59
Top employerAspen Dental
Top cityColumbia, SC
Cities hiring29
Work type100% On-site
Top industryHealthcare

Showing 5 of 59+ Dental Assistant jobs

Dental Assistant
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New 23h ago
Dental Assistant
Flossy Pediatric Dentistry
Myrtle Beach, South Carolina
Higher Education
K-12 Teaching
Teaching & Instruction
On-Site

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Certified Dental Assistant
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Added 1d ago
Certified Dental Assistant
Carimi Dental and Sedation
Daniel Island, South Carolina
Clinical Support
Healthcare Administration
Patient Services & Wellbeing
$25 - $30/hr

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Dental Assistant
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Added 1d ago
Dental Assistant
Pediatric Dentistry, PA
Greer, South Carolina
Clinical Support
Healthcare Administration
Patient Services & Wellbeing
$20 - $22/hr
On-Site

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Part-time Dental Assistant
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Added 3d ago
Part-time Dental Assistant
Armor Health
Columbia, South Carolina
Higher Education
Research & Academia
Teaching & Instruction
CPR Certification
1,001-5,000

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Dental Assistant
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Added 3d ago
Dental Assistant
LITTLE RIVER MEDICAL CENTER
Aynor, South Carolina
Account Management
Customer Service
Customer Success
X-Ray Certification
51-200

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Dental Assistant Jobs by City in South Carolina

Where South Carolina roles are concentrated, by current openings.

Columbia
7 jobs
Charleston
6 jobs
North Charleston
4 jobs
Greer
3 jobs
Conway
3 jobs
Bluffton
3 jobs
West Columbia
3 jobs
Anderson
2 jobs
Fort Mill
2 jobs

Dental Assistant Job Market in South Carolina

A snapshot from current South Carolina openings, updated as new roles post.

Who's Hiring

Aspen Dental8 open roles
Heartland Dental7 open roles
PDS Health2 open roles

Top Industries Hiring

  • Healthcare & Medical Services

What South Carolina Employers Look For

The qualifications that appear most often in dental assistant jobs across South Carolina.

  • Active South Carolina dental assistant registration or exemption status as required by the State Board of Dentistry
  • Completion of an accredited dental assisting program or equivalent on-the-job training hours
  • Current radiography certification to take and process dental X-rays independently
  • CPR and basic life support certification maintained at the time of hire
  • Experience with dental practice management software such as Dentrix or Eaglesoft
  • Strong chairside assisting skills including four-handed dentistry and instrument sterilization

Dental Assistant Jobs in South Carolina: Frequently Asked Questions

How do you become a dental assistant in South Carolina?

South Carolina dental assistants who perform certain clinical functions, including coronal polishing and sealant placement, must register with the South Carolina Board of Dentistry after completing an approved training program and meeting the board's competency requirements. General chairside assistants without expanded duties may work without state registration, but most employers prefer or require completion of an accredited dental assisting program. Radiography certification is a near-universal hiring requirement across the state.

Which companies hire dental assistants in South Carolina?

Employers hiring dental assistants in South Carolina right now include Aspen Dental, Heartland Dental, and PDS Health, based on current listings on Migrate Mate as of October 2026. South Carolina's mix of large health system-affiliated dental clinics and independently owned multi-location group practices means openings appear regularly across both corporate and community-focused settings statewide.

Which South Carolina cities have the most dental assistant jobs?

The South Carolina cities with the most dental assistant openings are Columbia, Charleston, and North Charleston. Columbia leads as the state capital and home to major health systems, Greenville draws volume from its fast-growing Upstate corridor anchored by large group practices and hospital-affiliated clinics, and Charleston's expanding coastal population supports a dense concentration of private practices and specialty offices.

Are there remote dental assistant jobs in South Carolina?

Yes, but they're rare. About 0% of dental assistant openings tied to South Carolina are remote or hybrid as of October 2026, reflecting that most duties require direct patient contact and in-office equipment. The small share of remote work in this field typically involves dental insurance coordination, treatment plan consulting, or administrative support roles attached to larger group practices.

How can I get hired as a dental assistant in South Carolina with little or no experience?

The most realistic entry path is enrolling in an accredited dental assisting program at a South Carolina technical college, such as Midlands Technical College or Trident Technical College, which combine hands-on clinical hours with classroom instruction and often connect graduates directly to local practices. Community health centers affiliated with Federally Qualified Health Centers across the state frequently hire new graduates for entry-level chairside roles. Completing radiography certification before applying gives candidates a measurable edge over others without clinical credentials.

Where can I find and apply to dental assistant jobs in South Carolina?

You can find and apply to dental assistant jobs in South Carolina on Migrate Mate, which lists current openings across the state. Search the available roles, find the ones that match your experience and location, and apply directly to the employers that interest you.

See All 59 Dental Assistant Jobs in South Carolina

Find roles in South Carolina that match your experience and apply in just a few clicks.

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