Dental Assistant Jobs in South Carolina
Dental assistant jobs in South Carolina are concentrated in private dental practices, community health centers, and multi-specialty group practices, with steady demand from entry-level chair-side roles through experienced expanded-duty positions. The busiest hiring markets are Columbia, Greenville, and Charleston, where established groups such as Prisma Health, Greenville Health System, and Aspen Dental maintain active rosters across multiple locations. Expanded-duty dental assisting and orthodontic assisting are the most in-demand specialties statewide. Scan the live roles below and apply to whichever ones fit.
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Rare opportunity to join an award winning pediatric practice !
Now Hiring: Dental Assistant
Flossy Pediatric Dentistry is looking for a dedicated, enthusiastic Dental Assistant to join our team!
What We’re Looking For: Kid-Friendly Personality: Someone who connects with kids, helping them feel comfortable and excited about dental care.
Educator at Heart: Passionate about teaching kids and parents the importance of dental hygiene in a way that’s engaging and easy to understand.
Team Player: Thrives in a collaborative environment, supporting colleagues and contributing to our practice’s positive atmosphere.
Patient-Centered: Committed to making children’s oral health a priority and dedicated to providing the highest level of care.
Why Join Flossy Pediatric Dentistry? Be part of a fun, family-oriented practice that’s focused on growth and innovation. Work with a team that values compassion, professionalism, and patient education. Make a lasting impact on children’s lives by fostering a love for dental health!
If you’re ready to join a practice that’s as passionate about kids’ smiles as you are, apply today!
Email Resume to: kelsea@flossypediatricdentistry.com
Pay: Up to $27.00 per hour
Benefits:
- 401(k)
- Paid time off
Work Location: In person
See All 59 Dental Assistant Jobs in South Carolina
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Find Dental Assistant JobsDental Assistant Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Dental Assistant Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Healthcare & Medical Services
What South Carolina Employers Look For
The qualifications that appear most often in dental assistant jobs across South Carolina.
- Active South Carolina dental assistant registration or exemption status as required by the State Board of Dentistry
- Completion of an accredited dental assisting program or equivalent on-the-job training hours
- Current radiography certification to take and process dental X-rays independently
- CPR and basic life support certification maintained at the time of hire
- Experience with dental practice management software such as Dentrix or Eaglesoft
- Strong chairside assisting skills including four-handed dentistry and instrument sterilization
Dental Assistant Jobs in South Carolina: Frequently Asked Questions
How do you become a dental assistant in South Carolina?
South Carolina dental assistants who perform certain clinical functions, including coronal polishing and sealant placement, must register with the South Carolina Board of Dentistry after completing an approved training program and meeting the board's competency requirements. General chairside assistants without expanded duties may work without state registration, but most employers prefer or require completion of an accredited dental assisting program. Radiography certification is a near-universal hiring requirement across the state.
Which companies hire dental assistants in South Carolina?
Employers hiring dental assistants in South Carolina right now include Aspen Dental, Heartland Dental, and PDS Health, based on current listings on Migrate Mate as of October 2026. South Carolina's mix of large health system-affiliated dental clinics and independently owned multi-location group practices means openings appear regularly across both corporate and community-focused settings statewide.
Which South Carolina cities have the most dental assistant jobs?
The South Carolina cities with the most dental assistant openings are Columbia, Charleston, and North Charleston. Columbia leads as the state capital and home to major health systems, Greenville draws volume from its fast-growing Upstate corridor anchored by large group practices and hospital-affiliated clinics, and Charleston's expanding coastal population supports a dense concentration of private practices and specialty offices.
Are there remote dental assistant jobs in South Carolina?
Yes, but they're rare. About 0% of dental assistant openings tied to South Carolina are remote or hybrid as of October 2026, reflecting that most duties require direct patient contact and in-office equipment. The small share of remote work in this field typically involves dental insurance coordination, treatment plan consulting, or administrative support roles attached to larger group practices.
How can I get hired as a dental assistant in South Carolina with little or no experience?
The most realistic entry path is enrolling in an accredited dental assisting program at a South Carolina technical college, such as Midlands Technical College or Trident Technical College, which combine hands-on clinical hours with classroom instruction and often connect graduates directly to local practices. Community health centers affiliated with Federally Qualified Health Centers across the state frequently hire new graduates for entry-level chairside roles. Completing radiography certification before applying gives candidates a measurable edge over others without clinical credentials.
Where can I find and apply to dental assistant jobs in South Carolina?
You can find and apply to dental assistant jobs in South Carolina on Migrate Mate, which lists current openings across the state. Search the available roles, find the ones that match your experience and location, and apply directly to the employers that interest you.
See All 59 Dental Assistant Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
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