Primary Care Physician Jobs in South Carolina

Primary Care Physician jobs in South Carolina represent one of the most consistently active hiring markets in the Southeast, concentrated heavily in community health centers, hospital-employed primary care practices, and rural health clinics serving underserved populations across the state. The greatest volume of openings clusters in Columbia, Greenville, and Charleston, where major systems like Prisma Health, MUSC Health, and Bon Secours anchor a substantial share of the physician workforce. Family medicine, internal medicine, and preventive care remain the most in-demand sub-specialties. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles29
Top employerCenterWell
Top cityColumbia, SC
Cities hiring19
Work type100% On-site
Top industryHealthcare

Showing 5 of 29+ Primary Care Physician jobs

Physician - Primary Care
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Added 3d ago
Physician - Primary Care
US Department of Veterans Affairs
Charleston, South Carolina
Healthcare Administration
Patient Services & Wellbeing
Physicians
$245k - $315k/yr
On-Site
Military encouraged
10,000+

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SOB $75,000 Primary Care Physician - Sumter, SC - Optum Colonial Healthcare
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Added 5d ago
SOB $75,000 Primary Care Physician - Sumter, SC - Optum Colonial Healthcare
Optum
Sumter, South Carolina
Healthcare Administration
Patient Services & Wellbeing
Physicians
$226k - $366k/yr
10,000+

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Nurse Practitioner / Physician Assistant – Primary Care (Full Time)
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Added 2w ago
Nurse Practitioner / Physician Assistant – Primary Care (Full Time)
PIMandPC
Mauldin, South Carolina
Healthcare Administration
Nursing
Patient Services & Wellbeing
On-Site
Doctoral degree

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Primary Care Physician
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Added 3w ago
Primary Care Physician
CenterWell
Seneca, South Carolina
Customer Service
Customer Support
Hospitality & Guest Services
$255k - $299k/yr
1,001-5,000

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Primary Care Physician
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Added 3w ago
Primary Care Physician
CenterWell
Anderson, South Carolina
Customer Service
Customer Support
Hospitality & Guest Services
$255k - $299k/yr
1,001-5,000

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See All 29 Primary Care Physician Jobs in South Carolina

Find roles in South Carolina that match your experience and apply in just a few clicks.

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Primary Care Physician Jobs by City in South Carolina

Where South Carolina roles are concentrated, by current openings.

Columbia
4 jobs
Sumter
3 jobs
Anderson
2 jobs
Ridgeland
2 jobs
Charleston
2 jobs
Greenville
2 jobs
Myrtle Beach
2 jobs
Aiken
1 job
Greer
1 job

Primary Care Physician Job Market in South Carolina

A snapshot from current South Carolina openings, updated as new roles post.

Who's Hiring

CenterWell7 open roles
Optum6 open roles
Oak Street Health, part of CVS Health5 open roles

Top Industries Hiring

  • Healthcare & Medical Services

What South Carolina Employers Look For

The qualifications that appear most often in primary care physician jobs across South Carolina.

  • Active South Carolina medical license issued by the South Carolina Board of Medical Examiners
  • Board certification or board eligibility in family medicine or internal medicine
  • Completion of an accredited residency program in a primary care specialty
  • Valid DEA registration and current South Carolina controlled substances license
  • Experience managing chronic disease panels including diabetes, hypertension, and cardiovascular conditions
  • Proficiency with electronic health record systems such as Epic or Cerner

Primary Care Physician Jobs in South Carolina: Frequently Asked Questions

How do you become a primary care physician in South Carolina?

To practice as a primary care physician in South Carolina, you must obtain a medical license from the South Carolina Board of Medical Examiners after completing medical school, residency training in a primary care specialty such as family medicine or internal medicine, and passing the USMLE or COMLEX licensing exams. South Carolina also requires a separate controlled substances registration for physicians who prescribe scheduled medications. Many candidates pursue board certification before applying to strengthen their candidacy with hospital-employed practices.

Which companies hire primary care physicians in South Carolina?

Employers hiring primary care physicians in South Carolina right now include CenterWell, Optum, and Oak Street Health, part of CVS Health, based on current listings on Migrate Mate as of October 2026. South Carolina's largest health systems, including Prisma Health and MUSC Health, consistently maintain open primary care physician positions across their employed medical group networks throughout the state.

Which South Carolina cities have the most primary care physician jobs?

Columbia, Sumter, and Anderson account for the greatest concentration of primary care physician openings in South Carolina. Columbia and Greenville drive demand through large hospital-employed group practices tied to Prisma Health and Bon Secours, while Charleston's market is anchored by MUSC Health and a growing number of outpatient and concierge primary care groups serving a rapidly expanding coastal population.

Are there remote primary care physician jobs in South Carolina?

Yes, but they're rare. About 0% of primary care physician openings tied to South Carolina are remote or hybrid as of October 2026, reflecting the hands-on, patient-facing nature of most primary care roles. The exceptions tend to be telehealth-specific physician positions, where providers conduct virtual urgent care or chronic disease management visits without requiring a physical clinic presence.

How can I get hired as a primary care physician in South Carolina with little or no experience?

The most realistic path for physicians without independent practice experience is applying through residency-to-employment pipelines at Prisma Health or MUSC Health, both of which maintain structured new-physician onboarding programs and regularly recruit graduating residents into employed primary care roles. Federally Qualified Health Centers operating across South Carolina's rural and underserved counties also hire physicians new to independent practice, often offering loan repayment incentives. Demonstrating board eligibility, rural medicine interest, and EHR familiarity gives candidates a concrete edge in the South Carolina market.

Where can I find and apply to primary care physician jobs in South Carolina?

You can find and apply to primary care physician jobs in South Carolina on Migrate Mate, which lists current openings from employers hiring in the state right now. Search the available roles, identify the ones that match your specialty and preferred location, and apply directly to whichever positions fit your background and goals.

See All 29 Primary Care Physician Jobs in South Carolina

Find roles in South Carolina that match your experience and apply in just a few clicks.

Find Primary Care Physician Jobs