Occupational Therapy Assistant Jobs in South Carolina
Occupational Therapy Assistant jobs in South Carolina concentrate heavily in skilled nursing facilities, inpatient rehabilitation centers, pediatric clinics, and school-based settings, with active hiring from entry-level to senior clinician roles. Columbia, Greenville, and Charleston lead in openings, anchored by large employers such as Prisma Health, Roper St. Francis Healthcare, and Encompass Health. The most in-demand specialties in South Carolina are pediatric therapy, geriatric rehabilitation, and hand therapy. Find a role that fits below and apply directly.
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Join PruittHealth as a licensed Certified Occupational Therapist Assistant and make a meaningful impact in patient care. We’re committed to delivering exceptional healthcare services while creating a supportive environment where our professionals can thrive. This role offers competitive compensation up to $100,000 annually, based on experience, schedule, and location, along with comprehensive benefits and a collaborative culture focused on growth and excellence.
PruittHealth will help you conquer your career goals. At PruittHealth, we are searching for therapists who are committed to serving our residents with care and compassion, and in return, we are committed to supporting your therapy career through annual merit increases, career growth programs, preceptorship, and more.
Investing in Our Employee-Partners with Benefits
- Advanced pay option
- Annual merit increases
- Relocation opportunities
- Paid onboarding & orientation
- Preceptorship Program & hands-on training
- 24 / 7 direct hotline support
- Employee Referral Bonus Program
- Access to PruittHealth Foundation & PruittHealth University resources
- Comprehensive health plans
- Assist in the execution of the occupational therapy care plan and treatment to patients as prescribed by the evaluating therapist and physician according to the State Practice Acts
- Perform clinical tasks, and communicate and document tasks in a timely and accurate manner
- Follow established policies and procedures as related to the scope of practice
- Recognize and respond to priorities in patient care
- Complete all required orientation, in-services, and trainings successfully
- Perform other related duties as necessary and as directed by supervisor
- Valid professional license in the state of practice
- Graduate of ACOTE accredited school and eligible to take or has passed the NBCOT exam. If foreign-trained, must meet the same qualifications as U.S. educational program requirements
We are eager to connect with you! Apply Now to get started at PruittHealth!
As an Equal Employment Opportunity employer, all qualified applicants will receive consideration without regard to race, color, religion, sex, national origin, disability, or veteran status.
For Florida Job Postings Only:
For more information regarding Florida’s Care Provider Background Screening Clearinghouse Education and Awareness, please visit https://info.flclearinghouse.com
See All 66 Occupational Therapy Assistant Jobs in South Carolina
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Find JobsOccupational Therapy Assistant Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Occupational Therapy Assistant Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Healthcare & Medical Services
- Education
- Sports & Recreation
What South Carolina Employers Look For
The qualifications that appear most often in occupational therapy assistant jobs across South Carolina.
- Active South Carolina occupational therapy assistant license issued by the SC Board of Occupational Therapy
- Associate degree from an ACOTE-accredited occupational therapy assistant program
- Certified Occupational Therapy Assistant credential from the National Board for Certification in Occupational Therapy
- Current CPR and Basic Life Support certification from an approved provider
- Experience documenting patient progress in electronic health records systems
- Ability to implement treatment plans under a licensed occupational therapist's supervision
Occupational Therapy Assistant Jobs in South Carolina: Frequently Asked Questions
How do you become a occupational therapy assistant in South Carolina?
You must hold an active occupational therapy assistant license issued by the South Carolina Board of Occupational Therapy, which operates under the South Carolina Department of Labor, Licensing and Regulation. To qualify, complete an associate degree from an ACOTE-accredited program, pass the NBCOT Certified Occupational Therapy Assistant examination, and submit a licensure application to the board. South Carolina also requires that you practice under the supervision of a licensed occupational therapist.
How much do occupational therapy assistants make in South Carolina?
Occupational therapy assistants in South Carolina earn a median of about $73,740 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $52,050 for the lowest 10% to over $87,860 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire occupational therapy assistants in South Carolina?
Companies currently hiring occupational therapy assistants in South Carolina include Broad River Rehab, Your Health Organization, and National HealthCare Corporation, per current listings on Migrate Mate as of August 2026. South Carolina's concentration of skilled nursing facilities, hospital-based rehabilitation units, and pediatric outpatient clinics means openings appear across both large health systems and independent specialty practices throughout the state.
Which South Carolina cities have the most occupational therapy assistant jobs?
Spartanburg, Columbia, and Sumter have the most occupational therapy assistant openings in South Carolina. Columbia's density of hospital systems and state government healthcare facilities drives the highest volume, while Greenville and Charleston generate strong demand through their expanding health system campuses, rehabilitation hospitals, and growing suburban pediatric clinic networks that serve rapidly increasing populations.
Are there remote occupational therapy assistant jobs in South Carolina?
Yes, but they're rare. Occupational therapy assistants work hands-on with patients, making the role inherently on-site by nature. About 20% of occupational therapy assistant openings tied to South Carolina are remote or hybrid as of August 2026, and those positions typically involve documentation review, telehealth-assisted care coordination, or supervisory consultation rather than direct patient treatment.
How can I get hired as a occupational therapy assistant in South Carolina with little or no experience?
The most realistic entry path is applying to new-graduate positions at South Carolina's larger rehabilitation hospital networks and skilled nursing facilities, which regularly hire candidates immediately after NBCOT certification. Prisma Health and Encompass Health operate structured clinical onboarding programs for newly licensed COTAs. Candidates who worked as occupational therapy aides or rehabilitation technicians during school carry an advantage, and completing your fieldwork rotations at South Carolina facilities often leads directly to a job offer.
Where can I find and apply to occupational therapy assistant jobs in South Carolina?
You can find and apply to occupational therapy assistant jobs in South Carolina on Migrate Mate, which lists current openings across the state. Find roles that fit your experience and location and apply directly to the employers posting them.
See All 66 Occupational Therapy Assistant Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
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