Medical Laboratory Technician Jobs in South Carolina
Medical Laboratory Technician jobs in South Carolina are in steady demand, concentrated across hospital systems, reference laboratories, and outpatient diagnostic centers, with openings at every level from entry-level technician to lead MLT. Most hiring is centered in Columbia, Charleston, and Greenville, where large employers such as Prisma Health, MUSC Health, and Bon Secours anchor the regional market. Hematology, microbiology, and blood banking are the most consistently sought specialties across the state. See the openings below and apply to the ones that match your experience.
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Showing 5 of 19+ Medical Laboratory Technician jobs
Thank you for considering a career at Roper St. Francis Healthcare!
*$7,500 SIGN ON BONUS*
HOURS: 8:30pm - 7:00am
NEW GRADUATES ENCOURAGED TO APPLY!
Primary Function/General Purpose of Position
Performs routine, and special diagnostic procedures requiring technical skill, judgment, and independent decision-making following established standards, policies and procedures. Performs phlebotomy and accessioning duties as needed. Assists the Laboratory Supervisor in the technical and administrative functions of the laboratory.
Essential Job Functions
Technical Procedures: Responsible for testing procedures, quality control, and proficiency testing to ensure that the test results meet the labs definition of quality – accurate, timely, appropriate, and useful. To this end verifies specimen integrity, sets priorities, evaluates and interprets data and take appropriate action per policy, performs appropriate documentation, assists in evaluation and implementation of new methods, assists with upkeep of policy/procedure manuals and CAP inspections. Is aware of resources and works efficiently to prevent waste.
Instrumentation: Responsible for the proper operation of instruments, preventive maintenance, and troubleshooting to enable test results to be timely and accurate. Operates lab instruments as assigned, performs instrument QC, documents results, and takes appropriate action. Performs preventive maintenance, troubleshoots instrument problems. Understands theory of instrument operations and mechanical functions. Seeks help when necessary.
Information Handling: Responsible for proper use of Cerner/STAR according to policy/procedure in ordering/receiving/ canceling tests, reviewing/verification of results. Responsible for review of pending lists and follow-up of pending tests. Documents all actions appropriately in computer. Documents all PMs, and QC appropriately. Maintains patient confidentiality per established policies.
Communication/Customer Service: Communicates information to supervisor/pathologist, coworkers or students, laboratory staff on other shifts, outside departments – accurately, timely, clearly, and professionally. Follows through on communications, responds as appropriate. Answers laboratory phones, directs parties or gives appropriate information. Communicates with physicians, nurses and patients to assist them with their needs. Maintains good rapport with peers, management, physicians and hospital staff.
Compliance/Safety: Is aware of and follows laboratory and hospital policies/procedures. Informs Supervisor of issues or problems involving laboratory or hospital safety. Maintains a safe work environment. Is knowledgeable of and follows regulations pertaining to medical necessity and billing as applicable to the job. Completes all mandatory education and participates in available continuing education programs. Works to meet department Performance Improvement Goals.
This document is not an exhaustive list of all responsibilities, skills, duties, requirements, or working conditions associated with the job. Employees may be required to perform other job-related duties as required by their supervisor, subject to reasonable accommodation.
Licensing/Certification
ASCP, ASCPI, NCA, or AMT registered as a MT, MLS, or IMLS.
Education
B.S. in Medical Technology, or Bachelors degree with prerequisite coursework and clinical training (required)
In lieu of a Bachelors degree, candidate must meet the alternate route requirements for education and training as set forth by ASCP, NCA, or AMT in order to be certified by ASCP, NCA, or AMT.
Work Experience
Not Required
Training
Language
Patient Population
The following must be included in all position descriptions that involve direct or indirect patient care. This is a Joint Commission requirement. Also, select the age of the patient population served:
X Demonstrates the knowledge and skills necessary to provide care appropriate to the age of the patients served on his or her assigned unit.
Demonstrates knowledge of the principles of growth and development of the life span and possesses the ability to assess data reflective of the patient's status and interprets the appropriate information needed to identify each patient's requirements relative to his or her age, specific needs and to provide the care needed as described in departmental policies and procedures.
Neonates (0-4 weeks)
Infant (1-12 months)
Pediatrics (1-12 years)
Adolescents (13-17 years)
Adults (18-64 years)
Geriatrics (65 years and older)
Not applicable to this position
Working Conditions/Physical Requirements
Frequent standing, walking, sitting, bending, stooping. May require lifting or moving items up to 50 lbs. Frequent use of finger/hand dexterity and eye/hand coordination. Frequent reaching with hands/arms. Corrected hearing and vision to normal range. Requires visual acuity and normal color perception needed for interpretation of lab orders and proper collection technique. Exposure to blood, body fluids or tissue. Possible exposure to communicable diseases, infections materials, toxic substances, biohazardous materials, and other conditions common to a laboratory environment. Normal laboratory environment. Ability to read and comprehend. Fast paced, high traffic work environment which may be interruptive and stressful. May be required to take call and/or work weekends/holidays based on the needs of the department.
Skills
Hard/Tech/Clinical Skills:
Must be capable of operating laboratory instrumentation, performing patient phlebotomy, and making sound, well-informed decisions under stressful conditions and time constraints.
Must demonstrate superior work knowledge and ability to organize and communicate clearly.
Must be able to use office equipment such as telephones, fax machines, computer terminals, etc.
Soft/Interpersonal Skills:
Demonstrates excellent organizational, leadership, interpersonal, and communication skills.
Must maintain strict confidentiality of work-related information.
Summary of Primary Function/General Purpose of Position
Medical Lab Technicians (MLT) assist physicians and other specialists by performing all aspects of testing on blood, tissue, and other bodily fluids, the results of which can then be used to diagnose and treat patients. Confirms test results and provides the physician with data necessary to make appropriate determinations.
Essential Job Functions
- Performs routine, moderate, and highly complex laboratory diagnostic tests.
- Confirms test results and provides the physician with data necessary to determine the presence, extent, cause, and treatment of disease.
- Follows quality control programs, assuring the accuracy and reliability of test results.
- Performs, records, and evaluates Quality Control.
- Monitors, maintains, and troubleshoots laboratory instruments and equipment.
- Assist with training of new employees and students in the use of lab equipment and testing procedures.
- Performs computer function on both Lab Information Systems (LIS) and Hospital Information Systems (HIS).
- Participates in continuing education in respective areas of expertise.
- Assists with inventory control.
This document is not an exhaustive list of all responsibilities, skills, duties, requirements, or working conditions associated with the job. Employees may be required to perform other job-related duties as required by their supervisor, subject to reasonable accommodation.
Licensing/Certification
MLT Medical Laboratory Technician Certification or eligible by a nationally recognized certification agency (preferably ASCP) (required) for BSMH.
For RSFH (as of 3/27/25) if registry-eligible, must achieve certification within 12 months from hire date.
Education
Must have one of the following:
Associates, Medical Lab Technology
Completed at least 60 semester hours (including six hours of chemistry and six of biology) of academic credit from a college or university accredited by a recognized regional or national accreditation agency and have successfully completed a medical lab technician program by a nationally accredited agency
Completed a 50-week U.S. military medical laboratory training course within the past ten years
Work Experience
2 years of technical experience in a clinical laboratory setting (preferred)
Training
None
Skills
Active Listening
Service Orientation
Coordination
Verbal and Written Communication
Problem Solving
Customer Service
Organization
Time Management
Data Entry
Microsoft Office
Telephone Skills
Lab Information Systems
Laboratory Diagnostic Tests
Analyze data
Laboratory equipment
Quality assurance and control
Chemistry
Biology
Phlebotomy
Patient care
Working Conditions
Periods of high stress and fluctuating workloads may occur
May be exposed to physical altercations and verbal abuse
May be required to use physical restraints
May be exposed to high noise levels and bright lights
May be exposed to limited hazardous substances or body fluids*
May be exposed to human blood and other potentially infectious materials*
May have periods of constant interruptions
Required to car travel to off-site locations, occasionally in adverse weather conditions
Prolonged periods of working alone
- Individuals in this position are required to exercise universal precautions, use personal protective equipment and devices, and learn the policies concerning infection control.
Physical Requirements
Lifting/Carrying (0-50 lbs.) 1-33%
Lifting/Carrying (50-100 lbs.) 0%
Push/Pull (0-50 lbs.) 1-33%
Push/Pull (50-100 lbs.) 1-33%
Stoop/Kneel 1-33%
Crawling 0%
Climbing 0%
Balance 1-33%
Bending 1-33%
Sitting 34-66%
Walking 67-100%
Standing 67-100%
Additional Physical Requirements/Hazards
Manual dexterity (eye/hand coordination)
Perform shift work
Hear alarms/telephone/audio recorder
Reach above shoulder
Repetitive arm/hand movements
Finger Dexterity
Color Vision
Acuity - far
Acuity - near
Depth perception
Use of latex products
Exposure to toxic/caustic/chemicals/detergents
Exposure to moving mechanical parts
Exposure to dust/fumes
Exposure to potential electrical shock
Exposure to x ray/electromagnetic energy
Exposure to high pitched noises
Gaseous risk exposure
Patient Population
Neonates (0-4 weeks)
Infant (1-12 months)
Pediatrics (1-12 years)
Adolescents (13-17 years)
Adults (18-64 years)
Geriatrics (65 years and older)
As a Roper St. Francis Healthcare teammate, you're part of a Mission that matters. We support your well-being—personally and professionally. Our benefits are built to grow with you and meet your unique needs, every step of the way.
What we offer
- Competitive pay, incentives, referral bonuses and 403(b) with employer contributions (when eligible)
- Medical, dental, vision, prescription coverage, HSA/FSA options, life insurance, mental health resources and discounts
- Paid time off, parental and FMLA leave, short- and long-term disability
- Tuition assistance, professional development and continuing education support
Benefits may vary based on the market and employment status
Roper St. Francis Healthcare is an equal opportunity employer.
It is our policy to abide by all Federal and State laws, as well as, the requirements of 41 CFR 60-1.4(a), 60-300.5(a) and 60-741.5(a).Accordingly, all applicants will receive consideration for employment without regard to race, color, national origin, religion, sex, sexual orientation, gender identity, age, genetic information, or protected veteran status, and will not be discriminated against on the basis of disability. If you are an individual with a disability and would like to request a reasonable accommodation as part of the employment selection process, please contact The Talent Acquisition Team at recruitment@RSFH.com
Thank you for considering a career at Roper St. Francis Healthcare!
*$7,500 SIGN ON BONUS*
HOURS: 8:30pm - 7:00am
NEW GRADUATES ENCOURAGED TO APPLY!
Primary Function/General Purpose of Position
Performs routine, and special diagnostic procedures requiring technical skill, judgment, and independent decision-making following established standards, policies and procedures. Performs phlebotomy and accessioning duties as needed. Assists the Laboratory Supervisor in the technical and administrative functions of the laboratory.
Essential Job Functions
Technical Procedures: Responsible for testing procedures, quality control, and proficiency testing to ensure that the test results meet the labs definition of quality – accurate, timely, appropriate, and useful. To this end verifies specimen integrity, sets priorities, evaluates and interprets data and take appropriate action per policy, performs appropriate documentation, assists in evaluation and implementation of new methods, assists with upkeep of policy/procedure manuals and CAP inspections. Is aware of resources and works efficiently to prevent waste.
Instrumentation: Responsible for the proper operation of instruments, preventive maintenance, and troubleshooting to enable test results to be timely and accurate. Operates lab instruments as assigned, performs instrument QC, documents results, and takes appropriate action. Performs preventive maintenance, troubleshoots instrument problems. Understands theory of instrument operations and mechanical functions. Seeks help when necessary.
Information Handling: Responsible for proper use of Cerner/STAR according to policy/procedure in ordering/receiving/ canceling tests, reviewing/verification of results. Responsible for review of pending lists and follow-up of pending tests. Documents all actions appropriately in computer. Documents all PMs, and QC appropriately. Maintains patient confidentiality per established policies.
Communication/Customer Service: Communicates information to supervisor/pathologist, coworkers or students, laboratory staff on other shifts, outside departments – accurately, timely, clearly, and professionally. Follows through on communications, responds as appropriate. Answers laboratory phones, directs parties or gives appropriate information. Communicates with physicians, nurses and patients to assist them with their needs. Maintains good rapport with peers, management, physicians and hospital staff.
Compliance/Safety: Is aware of and follows laboratory and hospital policies/procedures. Informs Supervisor of issues or problems involving laboratory or hospital safety. Maintains a safe work environment. Is knowledgeable of and follows regulations pertaining to medical necessity and billing as applicable to the job. Completes all mandatory education and participates in available continuing education programs. Works to meet department Performance Improvement Goals.
This document is not an exhaustive list of all responsibilities, skills, duties, requirements, or working conditions associated with the job. Employees may be required to perform other job-related duties as required by their supervisor, subject to reasonable accommodation.
Licensing/Certification
ASCP, ASCPI, NCA, or AMT registered as a MT, MLS, or IMLS.
Education
B.S. in Medical Technology, or Bachelors degree with prerequisite coursework and clinical training (required)
In lieu of a Bachelors degree, candidate must meet the alternate route requirements for education and training as set forth by ASCP, NCA, or AMT in order to be certified by ASCP, NCA, or AMT.
Work Experience
Not Required
Training
Language
Patient Population
The following must be included in all position descriptions that involve direct or indirect patient care. This is a Joint Commission requirement. Also, select the age of the patient population served:
X Demonstrates the knowledge and skills necessary to provide care appropriate to the age of the patients served on his or her assigned unit.
Demonstrates knowledge of the principles of growth and development of the life span and possesses the ability to assess data reflective of the patient's status and interprets the appropriate information needed to identify each patient's requirements relative to his or her age, specific needs and to provide the care needed as described in departmental policies and procedures.
Neonates (0-4 weeks)
Infant (1-12 months)
Pediatrics (1-12 years)
Adolescents (13-17 years)
Adults (18-64 years)
Geriatrics (65 years and older)
Not applicable to this position
Working Conditions/Physical Requirements
Frequent standing, walking, sitting, bending, stooping. May require lifting or moving items up to 50 lbs. Frequent use of finger/hand dexterity and eye/hand coordination. Frequent reaching with hands/arms. Corrected hearing and vision to normal range. Requires visual acuity and normal color perception needed for interpretation of lab orders and proper collection technique. Exposure to blood, body fluids or tissue. Possible exposure to communicable diseases, infections materials, toxic substances, biohazardous materials, and other conditions common to a laboratory environment. Normal laboratory environment. Ability to read and comprehend. Fast paced, high traffic work environment which may be interruptive and stressful. May be required to take call and/or work weekends/holidays based on the needs of the department.
Skills
Hard/Tech/Clinical Skills:
Must be capable of operating laboratory instrumentation, performing patient phlebotomy, and making sound, well-informed decisions under stressful conditions and time constraints.
Must demonstrate superior work knowledge and ability to organize and communicate clearly.
Must be able to use office equipment such as telephones, fax machines, computer terminals, etc.
Soft/Interpersonal Skills:
Demonstrates excellent organizational, leadership, interpersonal, and communication skills.
Must maintain strict confidentiality of work-related information.
Summary of Primary Function/General Purpose of Position
Medical Lab Technicians (MLT) assist physicians and other specialists by performing all aspects of testing on blood, tissue, and other bodily fluids, the results of which can then be used to diagnose and treat patients. Confirms test results and provides the physician with data necessary to make appropriate determinations.
Essential Job Functions
- Performs routine, moderate, and highly complex laboratory diagnostic tests.
- Confirms test results and provides the physician with data necessary to determine the presence, extent, cause, and treatment of disease.
- Follows quality control programs, assuring the accuracy and reliability of test results.
- Performs, records, and evaluates Quality Control.
- Monitors, maintains, and troubleshoots laboratory instruments and equipment.
- Assist with training of new employees and students in the use of lab equipment and testing procedures.
- Performs computer function on both Lab Information Systems (LIS) and Hospital Information Systems (HIS).
- Participates in continuing education in respective areas of expertise.
- Assists with inventory control.
This document is not an exhaustive list of all responsibilities, skills, duties, requirements, or working conditions associated with the job. Employees may be required to perform other job-related duties as required by their supervisor, subject to reasonable accommodation.
Licensing/Certification
MLT Medical Laboratory Technician Certification or eligible by a nationally recognized certification agency (preferably ASCP) (required) for BSMH.
For RSFH (as of 3/27/25) if registry-eligible, must achieve certification within 12 months from hire date.
Education
Must have one of the following:
Associates, Medical Lab Technology
Completed at least 60 semester hours (including six hours of chemistry and six of biology) of academic credit from a college or university accredited by a recognized regional or national accreditation agency and have successfully completed a medical lab technician program by a nationally accredited agency
Completed a 50-week U.S. military medical laboratory training course within the past ten years
Work Experience
2 years of technical experience in a clinical laboratory setting (preferred)
Training
None
Skills
Active Listening
Service Orientation
Coordination
Verbal and Written Communication
Problem Solving
Customer Service
Organization
Time Management
Data Entry
Microsoft Office
Telephone Skills
Lab Information Systems
Laboratory Diagnostic Tests
Analyze data
Laboratory equipment
Quality assurance and control
Chemistry
Biology
Phlebotomy
Patient care
Working Conditions
Periods of high stress and fluctuating workloads may occur
May be exposed to physical altercations and verbal abuse
May be required to use physical restraints
May be exposed to high noise levels and bright lights
May be exposed to limited hazardous substances or body fluids*
May be exposed to human blood and other potentially infectious materials*
May have periods of constant interruptions
Required to car travel to off-site locations, occasionally in adverse weather conditions
Prolonged periods of working alone
- Individuals in this position are required to exercise universal precautions, use personal protective equipment and devices, and learn the policies concerning infection control.
Physical Requirements
Lifting/Carrying (0-50 lbs.) 1-33%
Lifting/Carrying (50-100 lbs.) 0%
Push/Pull (0-50 lbs.) 1-33%
Push/Pull (50-100 lbs.) 1-33%
Stoop/Kneel 1-33%
Crawling 0%
Climbing 0%
Balance 1-33%
Bending 1-33%
Sitting 34-66%
Walking 67-100%
Standing 67-100%
Additional Physical Requirements/Hazards
Manual dexterity (eye/hand coordination)
Perform shift work
Hear alarms/telephone/audio recorder
Reach above shoulder
Repetitive arm/hand movements
Finger Dexterity
Color Vision
Acuity - far
Acuity - near
Depth perception
Use of latex products
Exposure to toxic/caustic/chemicals/detergents
Exposure to moving mechanical parts
Exposure to dust/fumes
Exposure to potential electrical shock
Exposure to x ray/electromagnetic energy
Exposure to high pitched noises
Gaseous risk exposure
Patient Population
Neonates (0-4 weeks)
Infant (1-12 months)
Pediatrics (1-12 years)
Adolescents (13-17 years)
Adults (18-64 years)
Geriatrics (65 years and older)
As a Roper St. Francis Healthcare teammate, you're part of a Mission that matters. We support your well-being—personally and professionally. Our benefits are built to grow with you and meet your unique needs, every step of the way.
What we offer
- Competitive pay, incentives, referral bonuses and 403(b) with employer contributions (when eligible)
- Medical, dental, vision, prescription coverage, HSA/FSA options, life insurance, mental health resources and discounts
- Paid time off, parental and FMLA leave, short- and long-term disability
- Tuition assistance, professional development and continuing education support
Benefits may vary based on the market and employment status
Roper St. Francis Healthcare is an equal opportunity employer.
It is our policy to abide by all Federal and State laws, as well as, the requirements of 41 CFR 60-1.4(a), 60-300.5(a) and 60-741.5(a).Accordingly, all applicants will receive consideration for employment without regard to race, color, national origin, religion, sex, sexual orientation, gender identity, age, genetic information, or protected veteran status, and will not be discriminated against on the basis of disability. If you are an individual with a disability and would like to request a reasonable accommodation as part of the employment selection process, please contact The Talent Acquisition Team at recruitment@RSFH.com
See All 19 Medical Laboratory Technician Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find JobsMedical Laboratory Technician Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Medical Laboratory Technician Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring
Top Industries Hiring
- Healthcare & Medical Services
What South Carolina Employers Look For
The qualifications that appear most often in medical laboratory technician jobs across South Carolina.
- Associate degree in clinical laboratory science or medical laboratory technology required
- ASCP, AMT, or equivalent national certification strongly preferred or required
- South Carolina laboratory personnel registration with DHEC or equivalent recognized credential
- Proficiency with laboratory information systems such as Epic Beaker or Meditech
- Experience in phlebotomy and specimen processing for high-volume laboratory settings
- Ability to work rotating shifts including nights, weekends, and on-call coverage
Medical Laboratory Technician Jobs in South Carolina: Frequently Asked Questions
How do you become a medical laboratory technician in South Carolina?
You become a medical laboratory technician in South Carolina by completing an accredited associate degree program in clinical laboratory technology and obtaining national certification through ASCP or AMT. South Carolina's Department of Health and Environmental Control requires laboratory personnel to register before working in a licensed clinical laboratory. Most employers accept candidates who hold a current ASCP MLT certification as meeting state registration requirements. Clinical externships completed during your degree are the primary route into your first position.
Which companies hire medical laboratory technicians in South Carolina?
Employers hiring medical laboratory technicians in South Carolina right now include McLeod Health, Beaufort Memorial Hospital, and Prisma Health, based on current listings on Migrate Mate as of August 2026. Large integrated health systems and reference laboratory networks account for the majority of open positions across the state.
Which South Carolina cities have the most medical laboratory technician jobs?
Hilton Head Island, Manning, and Columbia lead South Carolina in medical laboratory technician openings. Columbia and Charleston generate the largest volume because they anchor the state's two biggest health systems, Prisma Health and MUSC Health, while Greenville's growing hospital corridor driven by Prisma Health Upstate and Bon Secours Pelham Medical Center keeps demand strong in the Upstate region as well.
How can I get hired as a medical laboratory technician in South Carolina with little or no experience?
The most realistic entry path is applying to laboratory aide or specimen processor positions at major South Carolina health systems such as Prisma Health or MUSC Health, which regularly hire candidates without full MLT experience and provide on-the-job exposure alongside credentialed staff. Completing an NAACLS-accredited MLT program at Midlands Technical College or Trident Technical College, which include clinical rotations at in-state partner hospitals, gives candidates a meaningful edge. ASCP MLT certification earned before or immediately after graduation signals readiness to South Carolina hiring managers even without prior employment history.
Where can I find and apply to medical laboratory technician jobs in South Carolina?
You can find and apply to medical laboratory technician jobs in South Carolina on Migrate Mate, which lists current openings from employers across the state. Search the listings to identify roles that match your certification, shift availability, and specialty area, then apply directly to the positions that fit your background.
See All 19 Medical Laboratory Technician Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
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