Physical Therapist Assistant Jobs in South Carolina

Physical Therapist Assistant jobs in South Carolina are concentrated in Columbia, Greenville, and Charleston, where outpatient orthopedics, geriatric rehabilitation, and home health are the specialties driving the most consistent demand. Major employers with a lasting presence include Prisma Health, MUSC Health, and Encompass Health, all of which maintain ongoing pipelines for assistants at both entry and experienced levels. The market supports practitioners across inpatient, skilled nursing, and outpatient settings throughout the Midlands, Upstate, and Lowcountry regions. See the openings below and apply to the ones that match your experience.

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Overview

Open roles53
Top employerCORA Physical Therapy
Top cityColumbia, SC
Cities hiring36
Work type100% On-site
Top industryHealthcare

Showing 5 of 53+ Physical Therapist Assistant jobs

Home Health Physical Therapist Assistant-Per Diem
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Added 3d ago
Home Health Physical Therapist Assistant-Per Diem
CenterWell
Walterboro, South Carolina
Healthcare Administration
Patient Services & Wellbeing
Social Work & Counseling
$64k - $88k/yr
CPR Certification
1,001-5,000

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Physical Therapist Assistant
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Added 4d ago
Physical Therapist Assistant
Optum
Walterboro, South Carolina
Healthcare Administration
Medical Assistant
Patient Services & Wellbeing
$52k - $79k/yr
CPR Certification
10,000+

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Physical Therapist Assistant
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Added 5d ago
Physical Therapist Assistant
TransPerfect Health
Sumter, South Carolina
Business Operations
Program Management
Project Management
$28 - $36/hr

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Physical Therapist Assistant
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Added 6d ago
Physical Therapist Assistant
Carolina PT
Sumter, South Carolina
Healthcare Administration
Medical Assistant
Patient Services & Wellbeing
11-50

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Physical Therapist Assistant | Full-Time | Outpatient
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Added 6d ago
Physical Therapist Assistant | Full-Time | Outpatient
CORA Physical Therapy
Columbia, South Carolina
Healthcare Administration
Patient Services & Wellbeing
Public Health
$30 - $40/hr
1,001-5,000

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See All 53 Physical Therapist Assistant Jobs in South Carolina

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Physical Therapist Assistant Jobs by City in South Carolina

Where South Carolina roles are concentrated, by current openings.

Columbia
4 jobs
Aiken
3 jobs
Florence
3 jobs
Walterboro
3 jobs
Myrtle Beach
3 jobs
Sumter
2 jobs
Lexington
2 jobs
Rock Hill
2 jobs
Georgetown
2 jobs

Physical Therapist Assistant Job Market in South Carolina

A snapshot from current South Carolina openings, updated as new roles post.

Who's Hiring

CORA Physical Therapy7 open roles
Amedisys6 open roles
Reliant Rehabilitation6 open roles

Top Industries Hiring

  • Healthcare & Medical Services

What South Carolina Employers Look For

The qualifications that appear most often in physical therapist assistant jobs across South Carolina.

  • Active South Carolina physical therapist assistant license issued by the South Carolina Board of Physical Therapy Examiners
  • Associate degree in physical therapist assistant studies from a CAPTE-accredited program
  • Current CPR and Basic Life Support certification from an approved provider
  • Experience providing therapeutic interventions under the supervision of a licensed physical therapist
  • Familiarity with electronic medical records systems used in clinical rehabilitation settings
  • Strong communication skills for coordinating care with physical therapists, patients, and families

Physical Therapist Assistant Jobs in South Carolina: Frequently Asked Questions

How do you become a physical therapist assistant in South Carolina?

To work as a physical therapist assistant in South Carolina, you must hold a license issued by the South Carolina Board of Physical Therapy Examiners. The path starts with completing an associate degree from a CAPTE-accredited physical therapist assistant program, followed by passing the National Physical Therapy Examination for PTAs. Once you pass, you apply for licensure through the Board before practicing in any clinical setting.

How much do physical therapist assistants make in South Carolina?

Physical therapist assistants in South Carolina earn a median of about $70,500 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $47,510 for the lowest 10% to over $88,070 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire physical therapist assistants in South Carolina?

Employers hiring physical therapist assistants in South Carolina right now include CORA Physical Therapy, Amedisys, and Reliant Rehabilitation, based on current listings on Migrate Mate as of October 2026. Large integrated health systems such as Prisma Health and MUSC Health also maintain ongoing hiring pipelines for assistants across inpatient and outpatient settings throughout the state.

Which South Carolina cities have the most physical therapist assistant jobs?

Columbia, Aiken, and Florence have the most physical therapist assistant openings in South Carolina. Columbia drives volume as the state capital with its dense concentration of hospital systems and skilled nursing facilities, while Greenville's fast-growing Upstate healthcare sector and Charleston's academic medical and outpatient clinic network account for strong and consistent demand in those metros.

Are there remote physical therapist assistant jobs in South Carolina?

Yes, but they're rare. Physical therapist assistants work hands-on with patients, which means the vast majority of roles require in-person presence at a clinic, hospital, or patient home. About 0% of physical therapist assistant openings tied to South Carolina are remote or hybrid as of October 2026, and those limited exceptions tend to involve telehealth consultation support or administrative coordination duties rather than direct patient care.

How can I get hired as a physical therapist assistant in South Carolina with little or no experience?

The most realistic entry path is applying to new-graduate positions at skilled nursing facilities and inpatient rehabilitation units, which tend to have the highest turnover and are more open to candidates fresh from accredited programs. Large South Carolina employers like Encompass Health and Prisma Health regularly bring on new graduates and pair them with supervising therapists during onboarding. Completing your clinical rotations at a South Carolina facility is a proven way to convert a student placement into a job offer, and having your state license in hand before you apply gives you a clear edge over candidates still waiting on exam results.

Where can I find and apply to physical therapist assistant jobs in South Carolina?

You can find and apply to physical therapist assistant jobs in South Carolina on Migrate Mate, which lists current openings from employers hiring across the state right now. Search the listings to find roles that match your experience, specialty, and preferred location, then apply directly to the ones that fit.

See All 53 Physical Therapist Assistant Jobs in South Carolina

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