Graduate Nurse Jobs in South Carolina
Graduate Nurse jobs in South Carolina are concentrated in Columbia, Charleston, and Greenville, where large hospital systems and academic medical centers drive steady hiring at both new-graduate and experienced levels. Employers such as MUSC Health, Prisma Health, and Bon Secours St. Francis have established graduate nurse pipelines and hire regularly into med-surg, critical care, and labor and delivery units. Demand is particularly strong in intensive care settings and emergency nursing as South Carolina's population continues to grow. See the openings below and apply to the ones that match your experience.
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A transition to practice role for new graduate registered nurses who will be eligible to obtain their RN license
within 90 days of beginning employment.
- Under the direction, supervision, consultation and collaboration of the charge nurse or their designee,
Act within the state where the facility is located.
- Provide nursing care and services within the standards and scope of nursing practice, as defined within
corporate policies and procedures.
- Recent graduate from an accredited school of professional nursing required.
- Required to register for RN licensure exam (if an individual fails to pass first exam, job title changed and
- One or more years’ experience as a nursing assistant preferred.
- Temporary nursing permit issued to graduates of professional nursing program who have not yet taken
nurse under the supervision of a current licensed registered nurse within the state where the facility
provides services, and within the standards and scope of practice as defined by the state Nurse Practice
Act.
- CPR and de-escalation/restraint certification required (training available upon hire and offered by
- First aid may be required based on state or facility.
We are committed to providing equal employment opportunities to all applicants for employment regardless of an individual’s characteristics protected by applicable state, federal and local laws.
See All 8 Graduate Nurse Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find Graduate Nurse JobsGraduate Nurse Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Graduate Nurse Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Healthcare & Medical Services
- Education
What South Carolina Employers Look For
The qualifications that appear most often in graduate nurse jobs across South Carolina.
- Active South Carolina RN license or eligibility through NCLEX-RN after graduation
- Bachelor of Science in Nursing degree from an accredited program preferred
- Current BLS certification from the American Heart Association required
- Completion of an accredited nursing program with clinical rotation hours documented
- ACLS certification required or willingness to obtain within specified timeframe
- Strong clinical assessment skills demonstrated through supervised practicum experience
Graduate Nurse Jobs in South Carolina: Frequently Asked Questions
How do you become a graduate nurse in South Carolina?
You become a graduate nurse in South Carolina by completing an accredited nursing program and passing the NCLEX-RN, which the South Carolina State Board of Nursing administers licensure through. After passing, you apply for your South Carolina RN license directly through the Board. Most employers hire candidates who are NCLEX-eligible before graduation, allowing you to begin a new-graduate residency program and receive your license during onboarding.
Which companies hire graduate nurses in South Carolina?
Employers hiring graduate nurses in South Carolina right now include McLeod Health, Dialysis Clinic, and Fresenius Medical Care, based on current listings on Migrate Mate as of August 2026. South Carolina's largest health systems, including academic medical centers and regional hospital networks, run structured new-graduate residency cohorts that open multiple times each year across the state.
Which South Carolina cities have the most graduate nurse jobs?
Florence, Loris, and Dillon have the most graduate nurse openings in South Carolina. Columbia anchors the market as the state capital and home to major systems like Prisma Health and the University of South Carolina health programs, while Charleston's concentration of MUSC Health facilities and Greenville's growing Prisma and Bon Secours footprint drive hiring in those metros.
Are there remote graduate nurse jobs in South Carolina?
Yes, but they're rare. About 0% of graduate nurse openings tied to South Carolina are remote or hybrid as of August 2026, reflecting how hands-on bedside care dominates the role. The positions most likely to have a remote component are utilization review, case management, or telephone triage roles that some systems offer to nurses with initial clinical experience.
How can I get hired as a graduate nurse in South Carolina with little or no experience?
The most realistic entry path is applying directly to new-graduate nurse residency programs, which MUSC Health, Prisma Health, and Bon Secours St. Francis all run in South Carolina for candidates with limited or no post-graduation experience. These structured programs provide supervised clinical rotations and mentorship before you transition to independent practice. Having your South Carolina RN license in hand and a documented ACLS certification strengthens your application ahead of each residency cohort cycle.
Where can I find and apply to graduate nurse jobs in South Carolina?
You can find and apply to graduate nurse jobs in South Carolina on Migrate Mate, which lists current openings across the state. Search the listings, find the roles that fit your experience and preferred location, and apply directly to each one. No sign-up is required to see the available positions.
See All 8 Graduate Nurse Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
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