Psychiatric Nurse Practitioner Jobs in South Carolina
Psychiatric Nurse Practitioner jobs in South Carolina are concentrated in Charlotte-adjacent suburbs, Columbia, and Charleston, where large systems like Prisma Health, MUSC Health, and Palmetto Health Tuomey maintain ongoing psychiatric service lines. Demand is strongest in child and adolescent psychiatry, geriatric mental health, and substance use disorder treatment, reflecting the state's rural behavioral health shortage and expanding community mental health infrastructure. The market runs from early-career NPs in outpatient community settings to seasoned providers taking on supervisory or telepsychiatry-facing clinical roles. See the openings below and apply to the ones that match your experience.
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Showing 5 of 25+ Psychiatric Nurse Practitioner jobs











SUMMARY:
Our associates deliver a higher standard of business services to support medical care and behavioral health care. We maintain professionalism, integrity, and commitment as we solve problems and make lives easier.
ESSENTIAL FUNCTIONS:
Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
The Psychiatric Practitioner works with the treatment team to deliver care to patients
Evaluate, diagnose, and treat patients with mental, emotional, and behavioral disorders
Patient population: Adults + Adolescents; dual diagnosis, mental health, substance abuse
Provide follow up psychiatric care to individual case load: improve patient mental health outcomes, medication management, address comprehensive mental healthcare needs
Team-based integrated care: coordination with counselors to integrate psychiatry & counseling
Thematic focus on patient experience: optimizing for safety, patient satisfaction and access to care
Conduct psychiatric evaluations, develop treatment plans, and evaluate treatment results
Perform problem-focused, individualized medical assessments within psychiatric parameters
Be physically on-site at assigned correctional facility(s) on a regular basis
Examine patients as needed. The expectation is that you stay on-site until all patients that need to be seen are seen.
Prescribe medication (including narcotics) and treatment within your prescriptive authority, as appropriate in your professional medical judgement, and without regard to cost. When prescribing, you should be mindful of things such as, but not limited to, medication adverse reactions, medication interactions, substance abuse issues, mental health disorders, comorbidities, allergies, pain level, vital signs, contraindications, drug monitoring, etc. in the context of the individual patient. You should prescribe medication for the appropriate duration of time, as determined by your professional medical judgement.
Review patient medical records, as appropriate
Sign off on orders, as appropriate
Comply with the correctional facility’s policies and procedures, unless doing so would be counter to common sense
If a determination is made that off-site care would be more appropriate for the patient, work with medical staff to send the patient off site or make appointments with the understanding that this can be overruled by the Sheriff/Jailer
Endeavor to attend a minimum of 1 ACH medical conference per year
Any and all other duties as assigned
Must possess a current state license in the state in which services are to be provided (MD, DO, Nurse Practitioner, Physician’s Assistant, Psychiatry)
Board Certified
Current DEA registration
Experience in a primary care specialty, corrections, and/or managed health care delivery
Must be able to drive a motor vehicle
Basic Life Support (BLS) certification; hands-on training
Benefits (Benefits eligibility is determined by employment status):
- Referral program
- 401(k) w/employer match
- Health insurance
- Vision insurance
- Dental insurance
- Professional Development
- Paid Time Off
- Disability Insurance
See All 25 Psychiatric Nurse Practitioner Jobs in South Carolina
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Find JobsPsychiatric Nurse Practitioner Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Psychiatric Nurse Practitioner Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring



What South Carolina Employers Look For
The qualifications that appear most often in psychiatric nurse practitioner jobs across South Carolina.
- Active South Carolina APRN license with psychiatric-mental health nurse practitioner certification
- Board certification as a psychiatric-mental health nurse practitioner from ANCC or AANP
- Master of Science in Nursing or Doctor of Nursing Practice from an accredited program
- Prescriptive authority and DEA registration current in South Carolina
- Experience conducting psychiatric evaluations, diagnosing, and managing psychotropic medications
- Ability to collaborate with interdisciplinary teams in inpatient, outpatient, or community settings
Psychiatric Nurse Practitioner Jobs in South Carolina: Frequently Asked Questions
How do you become a psychiatric nurse practitioner in South Carolina?
You become a psychiatric nurse practitioner in South Carolina by completing an accredited graduate nursing program with a psychiatric-mental health specialty, then applying for APRN licensure through the South Carolina Board of Nursing. You must also hold national certification as a psychiatric-mental health nurse practitioner from the American Nurses Credentialing Center or the American Association of Nurse Practitioners. South Carolina also requires a separate application for prescriptive authority before you can practice independently.
How much do psychiatric nurse practitioners make in South Carolina?
Psychiatric nurse practitioners in South Carolina earn a median of about $123,290 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $97,080 for the lowest 10% to over $160,170 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire psychiatric nurse practitioners in South Carolina?
Companies currently hiring psychiatric nurse practitioners in South Carolina include LifeStance Health, Supportive Care, and Thriveworks, per current listings on Migrate Mate as of August 2026. South Carolina's large integrated health systems and its network of community mental health centers across the Midlands and Lowcountry regions are among the most consistent sources of full-time openings.
Which South Carolina cities have the most psychiatric nurse practitioner jobs?
Columbia, Greenville, and Yemassee have the most psychiatric nurse practitioner openings in South Carolina. Columbia and Charleston anchor the market because of their large academic medical centers and multi-site health systems, while Greenville and the Upstate region have grown steadily as Prisma Health and other systems have expanded behavioral health capacity to meet rising demand.
Are there remote psychiatric nurse practitioner jobs in South Carolina?
Yes, but they're rare. Psychiatric nurse practitioner work is largely hands-on and clinic-based, though telepsychiatry has created more remote-eligible openings than in most nursing specialties. About 93% of psychiatric nurse practitioner openings tied to South Carolina are remote or hybrid as of August 2026, and those roles are most commonly in medication management and follow-up care rather than initial evaluations or crisis response.
How can I get hired as a psychiatric nurse practitioner in South Carolina with little or no experience?
The most realistic entry path is applying to new-graduate NP programs or residency tracks at large South Carolina health systems such as MUSC Health and Prisma Health, which periodically run structured onboarding for early-career psychiatric APRNs. Candidates who have worked as registered nurses in behavioral health, inpatient psychiatry, or crisis stabilization units have a clear advantage. Completing your South Carolina APRN license and DEA registration before you apply removes the most common barrier employers cite when screening new-grad applicants.
Where can I find and apply to psychiatric nurse practitioner jobs in South Carolina?
You can find and apply to psychiatric nurse practitioner jobs in South Carolina on Migrate Mate, which lists current openings across the state. Search the roles that fit your credentials and experience level and apply directly to the ones that match.
See All 25 Psychiatric Nurse Practitioner Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
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