Psychiatric Nurse Practitioner Jobs in South Carolina

Psychiatric Nurse Practitioner jobs in South Carolina are concentrated in Charlotte-adjacent suburbs, Columbia, and Charleston, where large systems like Prisma Health, MUSC Health, and Palmetto Health Tuomey maintain ongoing psychiatric service lines. Demand is strongest in child and adolescent psychiatry, geriatric mental health, and substance use disorder treatment, reflecting the state's rural behavioral health shortage and expanding community mental health infrastructure. The market runs from early-career NPs in outpatient community settings to seasoned providers taking on supervisory or telepsychiatry-facing clinical roles. See the openings below and apply to the ones that match your experience.

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Overview

Open roles25
Top employerLifeStance Health
Top cityColumbia, SC
Cities hiring14
Work type60% Hybrid
Top credentialDoctoral degree

Showing 5 of 25+ Psychiatric Nurse Practitioner jobs

Advanced Correctional Healthcare
Psychiatric Nurse Practitioner
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Advanced Correctional Healthcare
Added 2d ago
Psychiatric Nurse Practitioner
Advanced Correctional Healthcare
Columbia, South Carolina
Business Development
Customer Success
Sales
$90 - $175/hr
Managed care
1,001-5,000

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LifeStance Health
Psychiatric Nurse Practitioner (PMHNP)
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LifeStance Health
Added 2d ago
Psychiatric Nurse Practitioner (PMHNP)
LifeStance Health
North Charleston, South Carolina
Healthcare Administration
Nursing
Patient Services & Wellbeing
$142k - $190k/yr
Hybrid
5,001-10,000

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Thriveworks
Part Time Remote Psychiatric Nurse Practitioner - Fee For Service
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Thriveworks
Added 2d ago
Part Time Remote Psychiatric Nurse Practitioner - Fee For Service
Thriveworks
Yemassee, South Carolina
Business Operations
Customer Service
Project Management
$65k - $94k/yr
Remote (US)
Master's degree in nursing
1,001-5,000

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Supportive Care
Psychiatric Nurse Practitioner
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Supportive Care
Added 2d ago
Psychiatric Nurse Practitioner
Supportive Care
Travelers Rest, South Carolina
Healthcare Administration
Nursing
Patient Services & Wellbeing

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Supportive Care
Psychiatric Nurse Practitioner
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Supportive Care
Added 2d ago
Psychiatric Nurse Practitioner
Supportive Care
Rock Hill, South Carolina
Business Operations
Project Management
Quality Assurance & Testing (QA Testing)

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See All 25 Psychiatric Nurse Practitioner Jobs in South Carolina

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Psychiatric Nurse Practitioner Jobs by City in South Carolina

Where South Carolina roles are concentrated, by current openings.

Columbia
4 jobs
Greenville
3 jobs
Yemassee
2 jobs
Rock Hill
2 jobs
Charleston
2 jobs
North Charleston
2 jobs
Cayce
1 job
Greer
1 job
Conway
1 job

Psychiatric Nurse Practitioner Job Market in South Carolina

A snapshot from current South Carolina openings, updated as new roles post.

Who's Hiring

LifeStance Health
LifeStance Health8 open roles
Supportive Care
Supportive Care3 open roles
Thriveworks
Thriveworks2 open roles

What South Carolina Employers Look For

The qualifications that appear most often in psychiatric nurse practitioner jobs across South Carolina.

  • Active South Carolina APRN license with psychiatric-mental health nurse practitioner certification
  • Board certification as a psychiatric-mental health nurse practitioner from ANCC or AANP
  • Master of Science in Nursing or Doctor of Nursing Practice from an accredited program
  • Prescriptive authority and DEA registration current in South Carolina
  • Experience conducting psychiatric evaluations, diagnosing, and managing psychotropic medications
  • Ability to collaborate with interdisciplinary teams in inpatient, outpatient, or community settings

Psychiatric Nurse Practitioner Jobs in South Carolina: Frequently Asked Questions

How do you become a psychiatric nurse practitioner in South Carolina?

You become a psychiatric nurse practitioner in South Carolina by completing an accredited graduate nursing program with a psychiatric-mental health specialty, then applying for APRN licensure through the South Carolina Board of Nursing. You must also hold national certification as a psychiatric-mental health nurse practitioner from the American Nurses Credentialing Center or the American Association of Nurse Practitioners. South Carolina also requires a separate application for prescriptive authority before you can practice independently.

How much do psychiatric nurse practitioners make in South Carolina?

Psychiatric nurse practitioners in South Carolina earn a median of about $123,290 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $97,080 for the lowest 10% to over $160,170 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire psychiatric nurse practitioners in South Carolina?

Companies currently hiring psychiatric nurse practitioners in South Carolina include LifeStance Health, Supportive Care, and Thriveworks, per current listings on Migrate Mate as of August 2026. South Carolina's large integrated health systems and its network of community mental health centers across the Midlands and Lowcountry regions are among the most consistent sources of full-time openings.

Which South Carolina cities have the most psychiatric nurse practitioner jobs?

Columbia, Greenville, and Yemassee have the most psychiatric nurse practitioner openings in South Carolina. Columbia and Charleston anchor the market because of their large academic medical centers and multi-site health systems, while Greenville and the Upstate region have grown steadily as Prisma Health and other systems have expanded behavioral health capacity to meet rising demand.

Are there remote psychiatric nurse practitioner jobs in South Carolina?

Yes, but they're rare. Psychiatric nurse practitioner work is largely hands-on and clinic-based, though telepsychiatry has created more remote-eligible openings than in most nursing specialties. About 93% of psychiatric nurse practitioner openings tied to South Carolina are remote or hybrid as of August 2026, and those roles are most commonly in medication management and follow-up care rather than initial evaluations or crisis response.

How can I get hired as a psychiatric nurse practitioner in South Carolina with little or no experience?

The most realistic entry path is applying to new-graduate NP programs or residency tracks at large South Carolina health systems such as MUSC Health and Prisma Health, which periodically run structured onboarding for early-career psychiatric APRNs. Candidates who have worked as registered nurses in behavioral health, inpatient psychiatry, or crisis stabilization units have a clear advantage. Completing your South Carolina APRN license and DEA registration before you apply removes the most common barrier employers cite when screening new-grad applicants.

Where can I find and apply to psychiatric nurse practitioner jobs in South Carolina?

You can find and apply to psychiatric nurse practitioner jobs in South Carolina on Migrate Mate, which lists current openings across the state. Search the roles that fit your credentials and experience level and apply directly to the ones that match.

See All 25 Psychiatric Nurse Practitioner Jobs in South Carolina

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