Certified Medical Assistant Jobs in South Carolina

Certified Medical Assistant jobs in South Carolina are consistently in demand, with hiring concentrated across physician practices, urgent care networks, and large health systems serving a growing and aging population. Columbia, Greenville, and Charleston lead in openings, with well-established employers like Prisma Health, MUSC Health, and Bon Secours St. Francis actively recruiting at every experience level from new graduates to senior clinical staff. The most sought-after specialties include primary care, pediatrics, and orthopedics. See the openings below and apply to the ones that match your experience.

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Overview

Open roles226+
Top employerPrisma Health
Top cityGreenville, SC
Cities hiring51
Work type96% On-site
Top industryHealthcare

Showing 5 of 226+ Certified Medical Assistant jobs

Certified Medical Assistant or Phlebotomist with Leadership Experience
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Added 1d ago
Certified Medical Assistant or Phlebotomist with Leadership Experience
ARCpoint Labs
Rock Hill, South Carolina
Healthcare Administration
Patient Services & Wellbeing
Public Health
$16 - $20/hr
On-Site
2-10

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Certified Medical Assistant
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Added 1d ago
Certified Medical Assistant
Piedmont Healthcare
North Augusta, South Carolina
Nursing
Clinical Support
Healthcare Administration
Medical Assistant
Patient Services & Wellbeing
On-Site
High School
10,000+

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Certified Medical Assistant - LCMG Beaufort
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Added 3d ago
Certified Medical Assistant - LCMG Beaufort
Beaufort Memorial Hospital
Beaufort, South Carolina
Clinical Support
Healthcare Administration
Medical Specialists
1,001-5,000

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Certified Medical Assistant
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Added 3d ago
Certified Medical Assistant
Armor Health
Columbia, South Carolina
Higher Education
Research & Academia
Teaching & Instruction
CPR Certification
1,001-5,000

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Certified Medical Assistant
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Added 3d ago
Certified Medical Assistant
Lexington Health
Columbia, South Carolina
Healthcare Administration
Medical Assistant
Patient Services & Wellbeing
BLS Certification
5,001-10,000

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Certified Medical Assistant Jobs by City in South Carolina

Where South Carolina roles are concentrated, by current openings.

Myrtle Beach
14 jobs
Mount Pleasant
14 jobs
Greenwood
7 jobs
Spartanburg
7 jobs
Little River
7 jobs
Sumter
6 jobs

Certified Medical Assistant Job Market in South Carolina

A snapshot from current South Carolina openings, updated as new roles post.

Who's Hiring

  • Prisma Health50
  • Roper St. Francis Healthcare40
  • Doctors Care16
  • McLeod Health13
  • Bon Secours9

Top Industries Hiring

  • Healthcare & Medical Services

What South Carolina Employers Look For

The qualifications that appear most often in certified medical assistant jobs across South Carolina.

  • Nationally recognized CMA credential such as AAMA or RMA required or strongly preferred
  • Completion of an accredited medical assistant program from an approved institution
  • Proficiency with electronic health record systems, particularly Epic or Athenahealth
  • Experience with clinical tasks including vital signs, phlebotomy, and patient intake
  • Strong written and verbal communication skills for patient-facing environments
  • Basic Life Support certification from the American Heart Association or Red Cross

Certified Medical Assistant Jobs in South Carolina: Frequently Asked Questions

How do you become a certified medical assistant in South Carolina?

South Carolina does not require a state-issued license for medical assistants, but most employers strongly prefer or require national certification. The most widely recognized credentials are the Certified Medical Assistant designation through the American Association of Medical Assistants and the Registered Medical Assistant credential through American Medical Technologists. Candidates typically complete an accredited medical assistant program at a community college or vocational school, such as programs offered through Midlands Technical College or Trident Technical College, before sitting for an exam.

Which companies hire certified medical assistants in South Carolina?

Employers hiring certified medical assistants in South Carolina right now include Prisma Health, Roper St. Francis Healthcare, and Doctors Care, based on current listings on Migrate Mate as of October 2026. South Carolina's large integrated health systems and expanding ambulatory care networks tend to post the most consistent volume of openings across the state.

Which South Carolina cities have the most certified medical assistant jobs?

The cities with the most certified medical assistant openings in South Carolina are Greenville, Columbia, and Charleston. Columbia and Greenville dominate because they anchor the state's two largest health systems, Prisma Health and Bon Secours, while Charleston's concentration of MUSC Health facilities and private specialty practices drives strong demand in the Lowcountry.

Are there remote certified medical assistant jobs in South Carolina?

Yes, but they're rare. Certified medical assistant work is largely hands-on and clinic-based, so fully remote roles are the exception rather than the rule. About 4% of certified medical assistant openings tied to South Carolina are remote or hybrid as of October 2026, and those positions are most commonly administrative or telehealth-support roles that handle scheduling, prior authorizations, or patient communication rather than direct clinical care.

How can I get hired as a certified medical assistant in South Carolina with little or no experience?

The most realistic entry path is completing an accredited medical assistant program and applying directly to large health systems that hire new graduates, with Prisma Health and MUSC Health both known for onboarding candidates fresh out of training. Candidates coming from adjacent roles such as medical receptionist, patient care technician, or phlebotomist often transition successfully into certified medical assistant positions at community health centers and urgent care clinics. Holding a current BLS certification and a nationally recognized credential like the AAMA's CMA gives entry-level applicants a meaningful advantage in South Carolina hiring.

Where can I find and apply to certified medical assistant jobs in South Carolina?

You can find and apply to certified medical assistant jobs in South Carolina on Migrate Mate, which lists current openings across the state. Search the roles that fit your experience, specialty, and preferred location, then apply directly to the ones that match.

See All 226+ Certified Medical Assistant Jobs in South Carolina

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