Certified Medical Assistant Jobs in Greenville, SC
Certified Medical Assistant jobs in Greenville are concentrated in the Haywood Road medical corridor, downtown's Main Street health district, and the expanding Eastside and Simpsonville area clinics, with steady demand across primary care, specialty practices, and urgent care. Employers hiring right now include Prisma Health, Bon Secours, and Advanced Dermatology and Cosmetic Surgery. Scan the live roles below and apply to whichever ones fit.
Find JobsOverview
Showing 5 of 240+ Certified Medical Assistant jobs











Inspire health. Serve with compassion. Be the difference.
Job Summary
Performs assigned patient care and related administrative duties under the direct supervision of the physician(s). Performs a variety of office/clerical duties as assigned by the office manager. Specific patient care responsibilities will be assigned by the supervising physician after competency is established.
Essential Functions
- All team members are expected to be knowledgeable and compliant with Prisma Health's purpose: Inspire health. Serve with compassion. Be the difference.
- Performs clinical, technical, administrative and clerical duties as directed by the physician and within the scope of training and certification, including point of care testing. Receives critical lab values, reports value to physician and documents notification in medical record.
- Prepares patients for examination and treatment. Obtains and records patients' chief complaints, current medications, vital signs, pain screening and allergies. Pends orders for physician signature.
- Prepares exam and treatment rooms. Prepares and maintains supplies and equipment for treatments, cleaning/sterilizing instruments as needed.
- Assists physician with examinations, tests, procedures, and office-based surgery. Apply splints, casts, dressings and remove sutures with competency. Report and assist during emergencies.
- Prepares and administers medications and immunizations as ordered by the physician, including p.o., vaginal and rectal suppositories, intradermal injection and intramuscular injection, after demonstrating competency and passing medication administration test.
- Receives and returns clinically related telephone calls after communicating with physician or registered nurse regarding medical concerns of the patient.
- Teaches patient and provide printed information, on physician request, about diagnosis, self-care within the scope of assigned duties, health promotion, disease prevention and community healthcare resources. Patient education must be documented in the medical record.
- Documents data and cares in the patient medical record.
- Completes medical insurance and other related forms for physician review. Communicates as needed with the patient, referral source and payor between visits. Completes patient registration, scheduling and billing tasks, pre-authorization and other general office/clerical duties as assigned. Schedules tests and treatments, as ordered by the physician.
- Performs other duties as assigned.
Supervisory/Management Responsibilities
- This is a non-management job that will report to a supervisor, manager, director, or executive.
Minimum Requirements
- Education: In South Carolina, completion of medical assistant training program from one of the following:
- Graduate of a medical assisting education program accredited by the CAAHEP, ABHES, or any accrediting agency recognized by the United States Department of Education.
- Completion of a Career and Technical Education Health Sciences Program approved by the South Carolina Department of Education.
- Military Training: Completion of a medical assisting program provided by a branch of the United States Military.
- Registered Apprenticeship: Completion of a medical assisting United States Department of Labor-approved Registered Apprenticeship program.
- Employer-Led Training: Completion of a training program delivered by a health care employer that aligns with a nationally accredited certification exam.
- Completion of the Prisma Health Certification Institute (PHCI) Fast Track Certified Medical Assistant (CMA) program.
- Education: In Tennessee-completion of an accredited medical assistant program preferred.
- Experience - No experience required.
In Lieu Of
- NA
Required Certifications, Registrations, Licenses
- Job Related Certification from one of the following: CMA (AAMA); RMA (AMT); CCMA(NHA); NCMA (NCCT); RMA (ARMA); NRCMA (NAHP); or RMA (AAMP)
Knowledge, Skills and Abilities
- NA
Grandfather Clause
- CMAs who obtained certification prior to 1/1/2020 and have maintained certification without lapse while working as a CMA are exempt from the education requirements.
- Current South Carolina incumbents hired after 1/1/2020 without the education indicated above, have until July 15, 2026, to complete the required state education requirements.
Work Shift
Day (United States of America)
Location
Hand Center - Greenville
Facility
2243 Hand Center - Greenville
Department
22431000 Hand Center - Greenville-Practice Operations
Share your talent with us! Our vision is simple: to transform healthcare for the benefits of the communities we serve. The transformation of healthcare requires talented individuals in every role here at Prisma Health.
See All 240+ Certified Medical Assistant Jobs in Greenville
Find roles in Greenville that match your experience and apply in just a few clicks.
Find JobsCertified Medical Assistant Job Market in Greenville
Who's Hiring
- Prisma Health116

- Bon Secours39

- Advanced Dermatology and Cosmetic Surgery15

- Doctors Care8
- proactive md8

Top Industries Hiring
- Healthcare & Medical Services
Certified Medical Assistant Jobs in Greenville: Frequently Asked Questions
How do I get a certified medical assistant job in Greenville?
Greenville's strongest hiring comes from its dense network of primary care clinics, multispecialty physician groups, and urgent care centers along the Haywood Road and Woodruff Road corridors, plus the large health system campuses anchoring downtown. Candidates with phlebotomy and EHR proficiency stand out in this market. Targeting outpatient and ambulatory settings first tends to yield the fastest results for new applicants here.
Which companies hire certified medical assistants in Greenville?
Companies currently hiring certified medical assistants in Greenville include Prisma Health, Bon Secours, and Advanced Dermatology and Cosmetic Surgery, per current listings on Migrate Mate as of August 2026. Greenville's employer mix leans heavily toward large health systems, independent multispecialty groups, and regional urgent care chains that maintain multiple clinic locations across the metro.
Are there remote certified medical assistant jobs in Greenville?
Yes, though opportunities are limited since most certified medical assistant work is hands-on and clinic-based. About 0% of certified medical assistant openings tied to Greenville are remote or hybrid as of August 2026, reflecting how few of these roles can shift off-site. The portions most likely to allow remote work in Greenville involve telehealth support and medical records coordination rather than direct patient care.
How can I get a certified medical assistant job in Greenville with little or no experience?
The most realistic entry path in Greenville is targeting the area's urgent care chains and community health centers, which regularly hire candidates who hold a CMA credential but have limited clinical hours. Greenville Technical College's clinical externship network connects graduates directly with local employers, giving new graduates a practical foot in the door. Entry-level medical receptionist or patient service roles at Greenville-area practices also serve as a common stepping stone into full clinical positions.
Which industries hire the most certified medical assistants in Greenville?
The sectors hiring the most certified medical assistants in Greenville are Healthcare & Medical Services, based on current listings on Migrate Mate as of August 2026. Greenville's role as the Upstate region's healthcare hub, combined with significant recent investment in outpatient and specialty care infrastructure, keeps demand in these sectors consistently active.
Related Jobs in South Carolina
See All 240+ Certified Medical Assistant Jobs in Greenville
Find roles in Greenville that match your experience and apply in just a few clicks.
Find Jobs