Medical Laboratory Scientist Jobs in South Carolina
Medical Laboratory Scientist jobs in South Carolina represent a consistently active market, concentrated in hospital systems, academic medical centers, and large reference laboratory networks, with openings at every level from entry-level staff scientist to senior or lead positions. The heaviest hiring is in Columbia, Greenville, and Charleston, where employers such as MUSC Health, Prisma Health, and Palmetto Health Tuomey maintain ongoing needs. Hematology, microbiology, and blood bank are among the most in-demand specialties across these systems. Find a role that fits below and apply directly.
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Showing 5 of 13+ Medical Laboratory Scientist jobs
Thank you for considering a career at Roper St. Francis Healthcare!
$7,500 Sign On Bonus
HOURS:
10:30pm-7:00am / Rotating Days
Job Description
Primary Function/General Purpose of Position
Performs routine, and special diagnostic procedures requiring technical skill, judgment, and independent decision-making following established standards, policies and procedures. Performs phlebotomy and accessioning duties as needed. Assists the Laboratory Supervisor in the technical and administrative functions of the laboratory.
Essential Job Functions
- Technical Procedures: Responsible for testing procedures, quality control, and proficiency testing to ensure that the test results meet the labs definition of quality – accurate, timely, appropriate, and useful. To this end verifies specimen integrity, sets priorities, evaluates and interprets data and take appropriate action per policy, performs appropriate documentation, assists in evaluation and implementation of new methods, assists with upkeep of policy/procedure manuals and CAP inspections. Is aware of resources and works efficiently to prevent waste.
- Instrumentation: Responsible for the proper operation of instruments, preventive maintenance, and troubleshooting to enable test results to be timely and accurate. Operates lab instruments as assigned, performs instrument QC, documents results, and takes appropriate action. Performs preventive maintenance, troubleshoots instrument problems. Understands theory of instrument operations and mechanical functions. Seeks help when necessary.
- Information Handling: Responsible for proper use of Cerner/STAR according to policy/procedure in ordering/receiving/ canceling tests, reviewing/verification of results. Responsible for review of pending lists and follow-up of pending tests. Documents all actions appropriately in computer. Documents all PMs, and QC appropriately. Maintains patient confidentiality per established policies.
- Communication/Customer Service: Communicates information to supervisor/pathologist, coworkers or students, laboratory staff on other shifts, outside departments – accurately, timely, clearly, and professionally. Follows through on communications, responds as appropriate. Answers laboratory phones, directs parties or gives appropriate information. Communicates with physicians, nurses and patients to assist them with their needs. Maintains good rapport with peers, management, physicians and hospital staff.
- Compliance/Safety: Is aware of and follows laboratory and hospital policies/procedures. Informs Supervisor of issues or problems involving laboratory or hospital safety. Maintains a safe work environment. Is knowledgeable of and follows regulations pertaining to medical necessity and billing as applicable to the job. Completes all mandatory education and participates in available continuing education programs. Works to meet department Performance Improvement Goals.
This document is not an exhaustive list of all responsibilities, skills, duties, requirements, or working conditions associated with the job. Employees may be required to perform other job-related duties as required by their supervisor, subject to reasonable accommodation.
Licensing/Certification
- ASCP, ASCPI, NCA, or AMT registered as a MT, MLS, or IMLS.
Education
- B.S. in Medical Technology, or Bachelors degree with prerequisite coursework and clinical training (required)
- In lieu of a Bachelors degree, candidate must meet the alternate route requirements for education and training as set forth by ASCP, NCA, or AMT in order to be certified by ASCP, NCA, or AMT.
Work Experience
- Not Required
Training
Language
Patient Population
The following must be included in all position descriptions that involve direct or indirect patient care. This is a Joint Commission requirement. Also, select the age of the patient population served:
X Demonstrates the knowledge and skills necessary to provide care appropriate to the age of the patients served on his or her assigned unit.
Demonstrates knowledge of the principles of growth and development of the life span and possesses the ability to assess data reflective of the patient's status and interprets the appropriate information needed to identify each patient's requirements relative to his or her age, specific needs and to provide the care needed as described in departmental policies and procedures.
Neonates (0-4 weeks)
Infant (1-12 months)
Pediatrics (1-12 years)
Adolescents (13-17 years)
Adults (18-64 years)
Geriatrics (65 years and older)
Not applicable to this position
Working Conditions/Physical Requirements
Frequent standing, walking, sitting, bending, stooping. May require lifting or moving items up to 50 lbs. Frequent use of finger/hand dexterity and eye/hand coordination. Frequent reaching with hands/arms. Corrected hearing and vision to normal range. Requires visual acuity and normal color perception needed for interpretation of lab orders and proper collection technique. Exposure to blood, body fluids or tissue. Possible exposure to communicable diseases, infections materials, toxic substances, biohazardous materials, and other conditions common to a laboratory environment. Normal laboratory environment. Ability to read and comprehend. Fast paced, high traffic work environment which may be interruptive and stressful. May be required to take call and/or work weekends/holidays based on the needs of the department.
Skills
Hard/Tech/Clinical Skills:
- Must be capable of operating laboratory instrumentation, performing patient phlebotomy, and making sound, well-informed decisions under stressful conditions and time constraints.
- Must demonstrate superior work knowledge and ability to organize and communicate clearly.
- Must be able to use office equipment such as telephones, fax machines, computer terminals, etc.
Soft/Interpersonal Skills:
- Demonstrates excellent organizational, leadership, interpersonal, and communication skills.
- Must maintain strict confidentiality of work-related information.
As a Roper St. Francis Healthcare teammate, you're part of a Mission that matters. We support your well-being—personally and professionally. Our benefits are built to grow with you and meet your unique needs, every step of the way.
What we offer
- Competitive pay, incentives, referral bonuses and 403(b) with employer contributions (when eligible)
- Medical, dental, vision, prescription coverage, HSA/FSA options, life insurance, mental health resources and discounts
- Paid time off, parental and FMLA leave, short- and long-term disability
- Tuition assistance, professional development and continuing education support
Benefits may vary based on the market and employment status
Roper St. Francis Healthcare is an equal opportunity employer.
It is our policy to abide by all Federal and State laws, as well as, the requirements of 41 CFR 60-1.4(a), 60-300.5(a) and 60-741.5(a).Accordingly, all applicants will receive consideration for employment without regard to race, color, national origin, religion, sex, sexual orientation, gender identity, age, genetic information, or protected veteran status, and will not be discriminated against on the basis of disability. If you are an individual with a disability and would like to request a reasonable accommodation as part of the employment selection process, please contact The Talent Acquisition Team at recruitment@RSFH.com
Thank you for considering a career at Roper St. Francis Healthcare!
$7,500 Sign On Bonus
HOURS:
10:30pm-7:00am / Rotating Days
Job Description
Primary Function/General Purpose of Position
Performs routine, and special diagnostic procedures requiring technical skill, judgment, and independent decision-making following established standards, policies and procedures. Performs phlebotomy and accessioning duties as needed. Assists the Laboratory Supervisor in the technical and administrative functions of the laboratory.
Essential Job Functions
- Technical Procedures: Responsible for testing procedures, quality control, and proficiency testing to ensure that the test results meet the labs definition of quality – accurate, timely, appropriate, and useful. To this end verifies specimen integrity, sets priorities, evaluates and interprets data and take appropriate action per policy, performs appropriate documentation, assists in evaluation and implementation of new methods, assists with upkeep of policy/procedure manuals and CAP inspections. Is aware of resources and works efficiently to prevent waste.
- Instrumentation: Responsible for the proper operation of instruments, preventive maintenance, and troubleshooting to enable test results to be timely and accurate. Operates lab instruments as assigned, performs instrument QC, documents results, and takes appropriate action. Performs preventive maintenance, troubleshoots instrument problems. Understands theory of instrument operations and mechanical functions. Seeks help when necessary.
- Information Handling: Responsible for proper use of Cerner/STAR according to policy/procedure in ordering/receiving/ canceling tests, reviewing/verification of results. Responsible for review of pending lists and follow-up of pending tests. Documents all actions appropriately in computer. Documents all PMs, and QC appropriately. Maintains patient confidentiality per established policies.
- Communication/Customer Service: Communicates information to supervisor/pathologist, coworkers or students, laboratory staff on other shifts, outside departments – accurately, timely, clearly, and professionally. Follows through on communications, responds as appropriate. Answers laboratory phones, directs parties or gives appropriate information. Communicates with physicians, nurses and patients to assist them with their needs. Maintains good rapport with peers, management, physicians and hospital staff.
- Compliance/Safety: Is aware of and follows laboratory and hospital policies/procedures. Informs Supervisor of issues or problems involving laboratory or hospital safety. Maintains a safe work environment. Is knowledgeable of and follows regulations pertaining to medical necessity and billing as applicable to the job. Completes all mandatory education and participates in available continuing education programs. Works to meet department Performance Improvement Goals.
This document is not an exhaustive list of all responsibilities, skills, duties, requirements, or working conditions associated with the job. Employees may be required to perform other job-related duties as required by their supervisor, subject to reasonable accommodation.
Licensing/Certification
- ASCP, ASCPI, NCA, or AMT registered as a MT, MLS, or IMLS.
Education
- B.S. in Medical Technology, or Bachelors degree with prerequisite coursework and clinical training (required)
- In lieu of a Bachelors degree, candidate must meet the alternate route requirements for education and training as set forth by ASCP, NCA, or AMT in order to be certified by ASCP, NCA, or AMT.
Work Experience
- Not Required
Training
Language
Patient Population
The following must be included in all position descriptions that involve direct or indirect patient care. This is a Joint Commission requirement. Also, select the age of the patient population served:
X Demonstrates the knowledge and skills necessary to provide care appropriate to the age of the patients served on his or her assigned unit.
Demonstrates knowledge of the principles of growth and development of the life span and possesses the ability to assess data reflective of the patient's status and interprets the appropriate information needed to identify each patient's requirements relative to his or her age, specific needs and to provide the care needed as described in departmental policies and procedures.
Neonates (0-4 weeks)
Infant (1-12 months)
Pediatrics (1-12 years)
Adolescents (13-17 years)
Adults (18-64 years)
Geriatrics (65 years and older)
Not applicable to this position
Working Conditions/Physical Requirements
Frequent standing, walking, sitting, bending, stooping. May require lifting or moving items up to 50 lbs. Frequent use of finger/hand dexterity and eye/hand coordination. Frequent reaching with hands/arms. Corrected hearing and vision to normal range. Requires visual acuity and normal color perception needed for interpretation of lab orders and proper collection technique. Exposure to blood, body fluids or tissue. Possible exposure to communicable diseases, infections materials, toxic substances, biohazardous materials, and other conditions common to a laboratory environment. Normal laboratory environment. Ability to read and comprehend. Fast paced, high traffic work environment which may be interruptive and stressful. May be required to take call and/or work weekends/holidays based on the needs of the department.
Skills
Hard/Tech/Clinical Skills:
- Must be capable of operating laboratory instrumentation, performing patient phlebotomy, and making sound, well-informed decisions under stressful conditions and time constraints.
- Must demonstrate superior work knowledge and ability to organize and communicate clearly.
- Must be able to use office equipment such as telephones, fax machines, computer terminals, etc.
Soft/Interpersonal Skills:
- Demonstrates excellent organizational, leadership, interpersonal, and communication skills.
- Must maintain strict confidentiality of work-related information.
As a Roper St. Francis Healthcare teammate, you're part of a Mission that matters. We support your well-being—personally and professionally. Our benefits are built to grow with you and meet your unique needs, every step of the way.
What we offer
- Competitive pay, incentives, referral bonuses and 403(b) with employer contributions (when eligible)
- Medical, dental, vision, prescription coverage, HSA/FSA options, life insurance, mental health resources and discounts
- Paid time off, parental and FMLA leave, short- and long-term disability
- Tuition assistance, professional development and continuing education support
Benefits may vary based on the market and employment status
Roper St. Francis Healthcare is an equal opportunity employer.
It is our policy to abide by all Federal and State laws, as well as, the requirements of 41 CFR 60-1.4(a), 60-300.5(a) and 60-741.5(a).Accordingly, all applicants will receive consideration for employment without regard to race, color, national origin, religion, sex, sexual orientation, gender identity, age, genetic information, or protected veteran status, and will not be discriminated against on the basis of disability. If you are an individual with a disability and would like to request a reasonable accommodation as part of the employment selection process, please contact The Talent Acquisition Team at recruitment@RSFH.com
See All 13 Medical Laboratory Scientist Jobs in South Carolina
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Find JobsMedical Laboratory Scientist Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Medical Laboratory Scientist Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring
Top Industries Hiring
- Healthcare & Medical Services
What South Carolina Employers Look For
The qualifications that appear most often in medical laboratory scientist jobs across South Carolina.
- Active ASCP Board of Certification as MLS(ASCP) or equivalent nationally recognized credential
- Bachelor's degree in medical laboratory science or a closely related clinical science field
- Proficiency with laboratory information systems and automated analyzer platforms
- Experience performing high-complexity testing across multiple laboratory disciplines
- Strong quality control and compliance knowledge consistent with CAP and CLIA standards
- Ability to work rotating shifts including evenings, weekends, and holidays as required
Medical Laboratory Scientist Jobs in South Carolina: Frequently Asked Questions
How do you become a medical laboratory scientist in South Carolina?
South Carolina does not issue a state license for medical laboratory scientists, so the path to employment runs through national certification. Most South Carolina employers require the MLS(ASCP) credential issued by the American Society for Clinical Pathology Board of Certification, which requires a bachelor's degree in medical laboratory science or an equivalent clinical science program. Completing an accredited program that includes clinical rotations is the standard entry point, and many South Carolina hospital systems give strong preference to ASCP-certified candidates at the time of hire.
Which companies hire medical laboratory scientists in South Carolina?
Employers hiring medical laboratory scientists in South Carolina right now include Prisma Health, Roper St. Francis Healthcare, and Tidelands Health, based on current listings on Migrate Mate as of October 2026. Large integrated health systems anchored in the state, including academic medical centers and regional hospital networks, drive the majority of full-time openings.
Which South Carolina cities have the most medical laboratory scientist jobs?
Charleston, Columbia, and Greenville consistently post the most medical laboratory scientist openings in South Carolina. Columbia and Charleston lead because of their large academic medical centers and flagship hospital campuses, while Greenville reflects the significant growth of Prisma Health's Upstate network, which has expanded laboratory services substantially over the past several years.
Are there remote medical laboratory scientist jobs in South Carolina?
Yes, but they're rare. Medical laboratory scientist work is fundamentally hands-on, requiring direct operation of analyzers and handling of patient specimens, so the role is not well suited to remote work by nature. About 0% of medical laboratory scientist openings tied to South Carolina are remote or hybrid as of October 2026, and those positions tend to be in laboratory informatics, data review, or telehealth-adjacent roles rather than bench work.
How can I get hired as a medical laboratory scientist in South Carolina with little or no experience?
The most realistic entry path is a new-graduate staff scientist position at a large South Carolina health system, where employers such as MUSC Health and Prisma Health regularly hire candidates directly from accredited MLS programs. Completing your ASCP certification before applying gives a measurable edge. Candidates who lack full MLS credentials sometimes enter through laboratory assistant or phlebotomist roles within the same systems, then move laterally once they complete their degree and certification requirements.
Where can I find and apply to medical laboratory scientist jobs in South Carolina?
You can find and apply to medical laboratory scientist jobs in South Carolina on Migrate Mate, which lists current openings across the state. Search the available roles, identify the ones that match your experience and specialty, and apply directly to the employers posting them.
See All 13 Medical Laboratory Scientist Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
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