Physician Assistant Jobs in South Carolina
Physician Assistant jobs in South Carolina concentrate in primary care, emergency medicine, and hospital-based specialty services, with demand spread across entry-level through senior clinical roles. The heaviest hiring is in and around Charleston, Columbia, and Greenville, where large systems such as MUSC Health, Prisma Health, and Bon Secours anchor consistent openings. Surgical specialties, urgent care, and orthopedics see the strongest recurring demand across the state. Scan the live roles below and apply to whichever ones fit.
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Description
. This is an on-site, contract position offering an excellent opportunity for an Associate-level physician to provide high-quality neurological care in a dynamic clinical environment. As part of our medical practice, you will play a vital role in diagnosing and treating patients with complex neurological conditions while collaborating with a multidisciplinary team of healthcare professionals.
In this role, you will be responsible for delivering comprehensive patient evaluations, developing treatment plans, and managing a wide range of neurological disorders. You will work closely with primary care physicians, specialists, and support staff to ensure seamless, patient-centered care. Your clinical expertise and commitment to excellence will directly contribute to the reputation and growth of our neurology services within the community and the broader healthcare network.
Responsibilities
- Provide thorough neurological consultations and comprehensive patient evaluations
- Diagnose and manage conditions such as epilepsy, stroke, migraine, multiple sclerosis, Parkinson's disease, and other neurological disorders
- Order, interpret, and follow up on diagnostic tests including EEG, EMG, MRI, CT, and lumbar puncture as clinically indicated
- Develop individualized, evidence-based treatment plans tailored to each patient's needs
- Collaborate with primary care physicians and other specialists to ensure coordinated and continuous patient care
- Document all patient encounters accurately and promptly in the electronic medical record (EMR) system
- Participate in on-call coverage and provide timely follow-up care as required
- Educate patients and their families on neurological conditions, treatment options, and preventive care measures
- Adhere to all clinical protocols, safety standards, and regulatory compliance requirements
- Stay current with the latest advancements in neurology through continuing medical education and professional development
Requirements
- Doctor of Medicine (MD) or Doctor of Osteopathic Medicine (DO) degree from an accredited medical school
- Board certification or board eligibility in Neurology
- Valid and unrestricted medical license to practice in the state
- Completion of an accredited residency program in Neurology
- Associate-level experience (typically 1–4 years) in clinical neurology practice
- Strong diagnostic and clinical assessment skills with attention to detail
- Excellent verbal and written communication skills for patient interaction and interdisciplinary collaboration
- Ability to work independently in a fast-paced clinical setting while also functioning effectively as part of a team
- Proficiency with electronic medical record (EMR) systems and standard medical documentation practices
- Current DEA registration and BLS/ACLS certification
Schedule: 7a-7p, 7 on/7 off
No call requirement
Patient Population: Adults
EMR: Epic
Must be board-certified
Paid travel & expenses
See All 45 Physician Assistant Jobs in South Carolina
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Find Physician Assistant JobsPhysician Assistant Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Physician Assistant Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring
Top Industries Hiring
- Education
- Healthcare & Medical Services
What South Carolina Employers Look For
The qualifications that appear most often in physician assistant jobs across South Carolina.
- Active Physician Assistant license issued or recognized by the South Carolina Board of Medical Examiners
- National certification from NCCPA with current PA-C credential in good standing
- Master's degree from an ARC-PA accredited physician assistant program
- DEA registration or eligibility to obtain one for prescribing roles
- Minimum one to two years of clinical experience in a relevant specialty
- Current BLS certification and ACLS certification for hospital-based positions
Physician Assistant Jobs in South Carolina: Frequently Asked Questions
How do you become a physician assistant in South Carolina?
You must hold an active license issued by the South Carolina Board of Medical Examiners, which requires graduating from an ARC-PA accredited program and passing the PANCE exam administered by NCCPA. After earning your PA-C credential, you apply directly to the Board for state licensure. South Carolina also requires PAs to practice under a supervising physician agreement, so securing that physician relationship is a necessary step before starting work.
How much do physician assistants make in South Carolina?
Physician assistants in South Carolina earn a median of about $122,490 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $77,620 for the lowest 10% to over $158,860 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire physician assistants in South Carolina?
Companies currently hiring physician assistants in South Carolina include 77 Consultants, Prisma Health Urgent Care, and Concentra, per current listings on Migrate Mate as of August 2026. South Carolina's largest health systems and regional hospital networks account for the majority of consistent openings across the state.
Which South Carolina cities have the most physician assistant jobs?
Columbia, Greenville, and South Carolina have the most physician assistant openings in South Carolina. Charleston drives demand through MUSC Health's academic medical campus and a growing network of specialty practices, Columbia anchors state government health services and Prisma Health's flagship facilities, and Greenville reflects the rapid population and healthcare infrastructure growth in the Upstate region.
Are there remote physician assistant jobs in South Carolina?
Yes, but they're rare. About 0% of physician assistant openings tied to South Carolina are remote or hybrid as of August 2026, reflecting the hands-on clinical nature of most PA roles. The exceptions tend to be in telemedicine, utilization review, or case management positions where direct patient contact is limited.
How can I get hired as a physician assistant in South Carolina with little or no experience?
The most realistic entry path is through new-graduate residency or fellowship programs, and South Carolina employers such as MUSC Health and Prisma Health have offered structured post-graduate PA training in areas like hospital medicine and primary care. Candidates without direct PA experience who hold clinical background as a paramedic, surgical technologist, or registered nurse gain a meaningful edge. Completing your South Carolina Board of Medical Examiners licensure before applying and targeting urgent care or outpatient primary care roles will open more doors than pursuing competitive specialty positions immediately.
Where can I find and apply to physician assistant jobs in South Carolina?
You can find and apply to physician assistant jobs in South Carolina on Migrate Mate, which lists current openings across the state. Search the available roles, identify the ones that match your specialty and experience, and apply directly to the positions that fit.
See All 45 Physician Assistant Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
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