Physician Assistant Jobs in South Carolina
Physician Assistant jobs in South Carolina concentrate in primary care, emergency medicine, and hospital-based specialty services, with demand spread across entry-level through senior clinical roles. The heaviest hiring is in and around Charleston, Columbia, and Greenville, where large systems such as MUSC Health, Prisma Health, and Bon Secours anchor consistent openings. Surgical specialties, urgent care, and orthopedics see the strongest recurring demand across the state. Scan the live roles below and apply to whichever ones fit.
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Are you a Nurse Practitioner or PA looking to join a fast-growing team making a difference in the way patients' wounds are being healed? If so, West Coast Wound is the right place to be!
West Coast Wound & Skin Care is a full-service mobile wound care company that delivers quality services/treatments to patients in the comfort of their own home. We are a fast-growing organization and our mission is to provide high-quality care, treating the whole patient's health, not just the wound. We have high and excellent standards for communication with the agencies we work with, are available and responsive to meet the treatment needs of our patients, and prioritize training/continuing education to our medical team.
We are seeking Nurse Practitioners or Physician Assistants to perform mobile advanced wound care services for our patients. You will travel locally within your designated region to see our patients in their homes or SNFs.
If you value dynamism and a job that releases you from the confines of an office, and allows you to work with a large degree of autonomy, this may be the role for you. West Coast Wound and Skin Care is looking for NURSE PRACTITIONERS AND PHYSICIAN ASSISTANTS living in or near Charleston and willing to drive to see patients in Charleston and surrounding areas.
Must be a licensed NP or PA in SC already.
This is not a remote position. Must be willing and able to drive to patient homes to provide wound care.
No experience is needed. We provide extensive training, 24/7 support and offer competitive compensation.
Responsibilities:
- Select, order, and perform tests and procedures to best treat the patient
- Perform wound care procedures as deemed necessary and appropriate for plan of care
- Define and document patient diagnoses
- Assure all patients are completely satisfied
- Patient education and management
- Debridement of wounds by various methods completed safely during the patient visit
- Application of topical wound care and other wound management products
- Notate findings and treatment course in patient chart, including follow-up notes
Qualifications:
- Current state license as an NP or PA
- CPR Certified
- Effective communication skills
- Excellent interpersonal and customer service skills
- Must have a valid driver’s license and minimum state required liability auto insurance; local travel is required
Compensation:
1099 only
PLEASE NOTE: West Coast Wound does NOT request any personal information via job forums.
Job Types: Full-time, Part-time
Pay: From $140,000.00 per year
Work Location: On the road
See All 51 Physician Assistant Jobs in South Carolina
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Find Physician Assistant JobsPhysician Assistant Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Physician Assistant Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring
- Prisma Health Urgent Care15P
- 77 Consultants37
- Michelin2

- PruittHealth2

- Curana Health2

Top Industries Hiring
- Healthcare & Medical Services
- Education
- Insurance
What South Carolina Employers Look For
The qualifications that appear most often in physician assistant jobs across South Carolina.
- Active Physician Assistant license issued or recognized by the South Carolina Board of Medical Examiners
- National certification from NCCPA with current PA-C credential in good standing
- Master's degree from an ARC-PA accredited physician assistant program
- DEA registration or eligibility to obtain one for prescribing roles
- Minimum one to two years of clinical experience in a relevant specialty
- Current BLS certification and ACLS certification for hospital-based positions
Physician Assistant Jobs in South Carolina: Frequently Asked Questions
How do you become a physician assistant in South Carolina?
You must hold an active license issued by the South Carolina Board of Medical Examiners, which requires graduating from an ARC-PA accredited program and passing the PANCE exam administered by NCCPA. After earning your PA-C credential, you apply directly to the Board for state licensure. South Carolina also requires PAs to practice under a supervising physician agreement, so securing that physician relationship is a necessary step before starting work.
How much do physician assistants make in South Carolina?
Physician assistants in South Carolina earn a median of about $122,490 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $77,620 for the lowest 10% to over $158,860 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire physician assistants in South Carolina?
Companies currently hiring physician assistants in South Carolina include Prisma Health Urgent Care, 77 Consultants, and Michelin, per current listings on Migrate Mate as of October 2026. South Carolina's largest health systems and regional hospital networks account for the majority of consistent openings across the state.
Which South Carolina cities have the most physician assistant jobs?
Charleston, Anderson, and Columbia have the most physician assistant openings in South Carolina. Charleston drives demand through MUSC Health's academic medical campus and a growing network of specialty practices, Columbia anchors state government health services and Prisma Health's flagship facilities, and Greenville reflects the rapid population and healthcare infrastructure growth in the Upstate region.
Are there remote physician assistant jobs in South Carolina?
Yes, but they're rare. About 14% of physician assistant openings tied to South Carolina are remote or hybrid as of October 2026, reflecting the hands-on clinical nature of most PA roles. The exceptions tend to be in telemedicine, utilization review, or case management positions where direct patient contact is limited.
How can I get hired as a physician assistant in South Carolina with little or no experience?
The most realistic entry path is through new-graduate residency or fellowship programs, and South Carolina employers such as MUSC Health and Prisma Health have offered structured post-graduate PA training in areas like hospital medicine and primary care. Candidates without direct PA experience who hold clinical background as a paramedic, surgical technologist, or registered nurse gain a meaningful edge. Completing your South Carolina Board of Medical Examiners licensure before applying and targeting urgent care or outpatient primary care roles will open more doors than pursuing competitive specialty positions immediately.
Where can I find and apply to physician assistant jobs in South Carolina?
You can find and apply to physician assistant jobs in South Carolina on Migrate Mate, which lists current openings across the state. Search the available roles, identify the ones that match your specialty and experience, and apply directly to the positions that fit.
See All 51 Physician Assistant Jobs in South Carolina
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