Care Assistant Jobs in South Carolina

Care Assistant jobs in South Carolina are concentrated in Columbia, Charleston, and Greenville, where growing senior populations and expanding health systems are driving consistent demand across memory care, home health, and assisted living. Major employers with a lasting presence in the state include Prisma Health, MUSC Health, and Encompass Health, which operate facilities and programs across multiple regions. Openings exist at every experience level, from entry-level positions in residential facilities to specialized roles supporting patients with complex needs. See the openings below and apply to the ones that match your experience.

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Overview

Open roles53
Top employerPrisma Health Urgent Care
Top cityColumbia, SC
Cities hiring33
Work type95% On-site
Top credentialHigh school diploma or GED

Showing 5 of 53+ Care Assistant jobs

Residential Care Facility Cook and Housekeeping Assistant
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Added 1d ago
Residential Care Facility Cook and Housekeeping Assistant
Eugenia’s Residential Care Facility
Columbia, South Carolina
Business Operations
Program Management
Project Management
$12 - $14.05/hr
On-Site

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Assistant Intermediate Care Facility Administrator: OIDD - Midlands
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Added 4d ago
Assistant Intermediate Care Facility Administrator: OIDD - Midlands
State of South Carolina
Richland County, SC
Healthcare Administration
Patient Services & Wellbeing
Social Work & Counseling
$68k - $95k/yr
Bachelor's degree
10,000+

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Personal Care Assistant
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Added 5d ago
Personal Care Assistant
Arcus Health Services
Johnsonville, South Carolina
Allied Health
Community & Nonprofit Services
Human Resources
Social Work & Counseling
$13 - $15/hr
On-Site

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Certified Nursing Assistant - ALL SHIFTS - Long Term Care
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Added 5d ago
Certified Nursing Assistant - ALL SHIFTS - Long Term Care
Carlyle Senior Care of Blackville
Blackville, South Carolina
Healthcare Administration
Nursing
Patient Services & Wellbeing
On-Site
CPR Certification

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Certified Medical Assistant, or LPN- Full Circle Care
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Added 5d ago
Certified Medical Assistant, or LPN- Full Circle Care
Self Regional Healthcare
Greenwood, South Carolina
Clinical Support
Healthcare Administration
Medical Specialists
High school diploma or GED
1,001-5,000

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See All 53 Care Assistant Jobs in South Carolina

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Care Assistant Jobs by City in South Carolina

Where South Carolina roles are concentrated, by current openings.

Columbia
6 jobs
Anderson
4 jobs
Lexington
3 jobs
Mount Pleasant
3 jobs
Seneca
2 jobs
Cassatt
2 jobs
Blackville
2 jobs
Charleston
2 jobs
Greenville
2 jobs

Care Assistant Job Market in South Carolina

A snapshot from current South Carolina openings, updated as new roles post.

Who's Hiring

Prisma Health Urgent Care9 open roles
Roper St. Francis Healthcare4 open roles
A First Name Basis3 open roles

What South Carolina Employers Look For

The qualifications that appear most often in care assistant jobs across South Carolina.

  • Active South Carolina CNA certification or eligibility to sit for the state competency exam
  • High school diploma or GED recognized by a South Carolina accredited institution
  • Current CPR and first aid certification from an accredited provider
  • Experience with personal care tasks including bathing, grooming, and mobility assistance
  • Ability to pass a South Carolina criminal background check and drug screening
  • Reliable transportation to reach client homes or facilities across assigned service areas

Care Assistant Jobs in South Carolina: Frequently Asked Questions

How do you become a care assistant in South Carolina?

To work as a care assistant in South Carolina, most positions require completing a state-approved nursing assistant training program and passing the South Carolina Nurse Aide Competency Evaluation, which is administered through the South Carolina Department of Health and Environmental Control. Programs are offered at technical colleges including Midlands Technical College and Trident Technical College. After passing the written and skills exams, candidates are listed on the South Carolina Nurse Aide Registry, which employers verify before hiring.

Which companies hire care assistants in South Carolina?

Employers hiring care assistants in South Carolina right now include Prisma Health Urgent Care, Roper St. Francis Healthcare, and A First Name Basis, based on current listings on Migrate Mate as of October 2026. South Carolina's large integrated health systems and growing network of assisted living communities across the Midlands and Lowcountry region account for a significant share of ongoing openings.

Which South Carolina cities have the most care assistant jobs?

Columbia, Anderson, and Lexington consistently lead South Carolina in care assistant openings. Columbia anchors the market as the state capital and home to major health systems like Prisma Health, while Charleston's expanding medical corridor and retirement communities drive strong demand in the Lowcountry, and Greenville's rapid population growth has made it one of the most active hiring areas in the Upstate region.

Are there remote care assistant jobs in South Carolina?

Yes, but they're rare. About 5% of care assistant openings tied to South Carolina are remote or hybrid as of October 2026, reflecting the hands-on nature of most care assistant work. The small share of remote roles tends to involve care coordination, scheduling support, or telehealth assistance rather than direct personal care duties.

How can I get hired as a care assistant in South Carolina with little or no experience?

The most realistic entry path is enrolling in a short-term state-approved nursing assistant program at a South Carolina technical college, completing the required clinical hours, and applying to entry-level aide positions at assisted living facilities or home health agencies. Prisma Health and Encompass Health both hire candidates who have completed their certification but have limited hands-on experience, and a listing on the South Carolina Nurse Aide Registry is the credential that most opens the door to first interviews.

Where can I find and apply to care assistant jobs in South Carolina?

You can find and apply to care assistant jobs in South Carolina on Migrate Mate, which lists current openings across the state. Search for roles that fit your experience level and location, then apply directly to the positions that match.

See All 53 Care Assistant Jobs in South Carolina

Find roles in South Carolina that match your experience and apply in just a few clicks.

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