NP Jobs in Columbia, SC

NP jobs in Columbia, South Carolina are concentrated in healthcare systems anchored in the Midlands corridor, with strong demand across primary care, urgent care, and specialty practices near the Five Points medical district, Forest Acres, and the downtown Congaree health hub. Employers actively hiring include Prisma Health, Concentra, and TeamHealth. See the openings below and apply to the ones that match your experience.

Find NP Jobs in Columbia

Overview

Open roles75
Top employerPrisma Health
Work type50% Remote
Top credentialMaster's degree in nursing
Companies hiring9

Showing 5 of 75+ NP jobs

R
Remote Virtual Nurse Practitioner
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R
Added 1d ago
Remote Virtual Nurse Practitioner
Remote Care Partners
Columbia, South Carolina
Allied Health
Healthcare Administration
Nursing
$95k - $115k/yr
Remote (US)

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TeamHealth
Emergency Medicine Advanced Practice Clinician In Columbia, SC
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TeamHealth
Added 1d ago
Emergency Medicine Advanced Practice Clinician In Columbia, SC
TeamHealth
Columbia, South Carolina
Allied Health
Healthcare Administration
Nursing
PALS Certification
10,000+

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Advanced Correctional Healthcare
Psychiatric Nurse Practitioner
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Advanced Correctional Healthcare
Added 2d ago
Psychiatric Nurse Practitioner
Advanced Correctional Healthcare
Columbia, South Carolina
Business Development
Customer Success
Sales
$90 - $175/hr
Managed care
1,001-5,000

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M
Nurse Practitioner
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M
Added 2d ago
Nurse Practitioner
Midlands Neurology and Pain Associates
Columbia, South Carolina
Allied Health
Healthcare Administration
Mental & Behavioral Health
Social Work & Counseling

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US Department of Veterans Affairs
Primary Care Nurse Practitioner
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US Department of Veterans Affairs
Added 2d ago
Primary Care Nurse Practitioner
US Department of Veterans Affairs
Columbia, South Carolina
Content Marketing
Copywriting & Editorial
Marketing
$104k - $173k/yr
On-Site
Post-Master's Certificate (Nursing)
10,000+

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See All 75 NP Jobs in Columbia

Find roles in Columbia that match your experience and apply in just a few clicks.

Find NP Jobs in Columbia

NP Job Market in Columbia

Who's Hiring

  • Prisma Health
    Prisma Health15
  • Concentra
    Concentra8
  • TeamHealth
    TeamHealth8
  • Agape Care
    Agape Care8
  • R
    Remote Care Partners8

NP Jobs in Columbia: Frequently Asked Questions

How do I get a np job in Columbia?

Focus your search on Columbia's largest healthcare anchors, including hospital-affiliated multispecialty groups, federally qualified health centers serving underserved Midlands communities, and the growing network of urgent care and retail health clinics along Harbison Boulevard and Two Notch Road. Candidates with experience in family medicine, psychiatric mental health, or acute care tend to move fastest in this market, and any existing familiarity with South Carolina Medicaid patient populations is a genuine advantage with local employers.

Which companies hire nps in Columbia?

Columbia np roles are posted by Prisma Health, Concentra, and TeamHealth and others right now, based on current listings on Migrate Mate as of August 2026. The local market is anchored by large academic medical systems, community health organizations, and an expanding footprint of independent and corporate-owned specialty clinics throughout the greater Richland County area.

Are there remote np jobs in Columbia?

Yes, though remote work is limited for nps since most roles require direct patient contact and on-site clinical presence. About 50% of np openings tied to Columbia are remote or hybrid as of August 2026, concentrated in telehealth triage, behavioral health, and care management roles. Columbia's growing telehealth infrastructure, supported by several regional health systems, makes those remote-eligible positions more available here than in smaller South Carolina markets.

How can I get a np job in Columbia with little or no experience?

The most realistic entry path in Columbia is through residency or fellowship programs affiliated with the Midlands health systems, which are designed specifically for new graduate nps and provide supervised clinical hours in high-volume settings. Entry-level candidates often find traction at federally qualified health centers and community clinics in the greater Columbia area, where patient volume is high and mentorship structures are built in. Highlighting any clinical rotations completed in South Carolina and any experience with underserved or complex populations will strengthen your application with local hiring managers.

See All 75 NP Jobs in Columbia

Find roles in Columbia that match your experience and apply in just a few clicks.

Find NP Jobs in Columbia