NP Jobs in Columbia, SC
NP jobs in Columbia, South Carolina are concentrated in healthcare systems anchored in the Midlands corridor, with strong demand across primary care, urgent care, and specialty practices near the Five Points medical district, Forest Acres, and the downtown Congaree health hub. Employers actively hiring include Prisma Health, Medical University of South Carolina, and Lexington Health. See the openings below and apply to the ones that match your experience.
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- R-0000064295
- Camden, South Carolina
- Columbia, South Carolina
- Advanced Practice Providers
- Nursing, Advanced Practice Providers, & Therapists
- Full Time
Job Description Summary
MUSC Health – Kershaw Medical Center is seeking a motivated and team-oriented Advanced Practice Provider (Nurse Practitioner or Physician Assistant) to join our growing Orthopedic program. This is an exciting opportunity to work alongside a highly collaborative orthopedic team focused on delivering exceptional inpatient and outpatient musculoskeletal care in a community centered environment.As an Orthopedic Surgery APP, you will play a vital role in caring for orthopedic patients across both the hospital and clinic settings, supporting inpatient rounding, consults, admissions, discharges, perioperative care, and outpatient follow-up management. This position offers the opportunity to work closely with orthopedic surgeons and multidisciplinary teams while providing seamless patient care throughout the surgical and recovery process, with a strong emphasis on teamwork, patient experience, and professional development.
Entity
MUSC Community Physicians (MCP)Worker Type
EmployeeWorker Sub-Type
RegularCost Center
CC001880 MCP - Columbia OrthopedicsPay Rate Type
Hourly, SalaryPay Grade
Health-33Scheduled Weekly Hours
40Work Shift
Job Description
MUSC Health – Kershaw Medical Center is seeking a motivated and team-oriented Advanced Practice Provider (Nurse Practitioner or Physician Assistant) to join our growing Orthopedic program. This is an exciting opportunity to work alongside a highly collaborative orthopedic team focused on delivering exceptional inpatient and outpatient musculoskeletal care in a community centered environment.
As an Orthopedic Surgery APP, you will play a vital role in caring for orthopedic patients across both the hospital and clinic settings, supporting inpatient rounding, consults, admissions, discharges, perioperative care, and outpatient follow-up management. This position offers the opportunity to work closely with orthopedic surgeons and multidisciplinary teams while providing seamless patient care throughout the surgical and recovery process, with a strong emphasis on teamwork, patient experience, and professional development.
About MUSC Health – Kershaw Medical Center and MUSC Health – Elgin Medical Pavilion:
MUSC Health – Kershaw Medical Center is a modern, community-based hospital serving Camden, South Carolina, and the surrounding Midlands region. As part of the nationally recognized MUSC Health system, Kershaw Medical Center combines personalized, community-focused care with the innovation, resources, and clinical excellence of South Carolina’s leading academic health system.
Providers benefit from a collegial, team-oriented environment, strong administrative support, and the opportunity to make a meaningful impact on patient outcomes within a growing and evolving service line.
Extending this commitment to accessible, high-quality care, MUSC Health – Elgin Medical Pavilion serves as a state-of-the-art outpatient hub in one of the Midlands’ fastest-growing communities. Located in Elgin, the pavilion offers convenient access to urgent care, primary care, and specialty services, supporting patients across Elgin, Lugoff, Camden, and the greater Columbia area.
Together, these facilities create a seamless continuum of care, allowing providers to practice in a collaborative environment that blends the close-knit feel of community medicine with the strength and support of a leading academic health system.
Required Qualifications:
Advanced Practice Provider: Nurse Practitioner (NP) or Physician Assistant (PA)
Orthopedic, surgical, hospital medicine, or acute care experience preferred
Ability to work collaboratively in a multidisciplinary team environment
Strong clinical judgment, communication, and patient management skills
Passion for delivering compassionate, high-quality patient care
Position Highlights:
Manage orthopedic inpatients in collaboration with orthopedic surgeons and hospital teams
Conduct daily rounding, patient evaluations, admissions, consultations, and discharges
Assist with perioperative care coordination and postoperative management
Support orthopedic surgical workflows and continuity of care across inpatient services
Participate in patient and family education to optimize recovery and outcomes
Collaborate closely with nursing, rehabilitation, case management, and ancillary teams
Contribute to a culture centered on teamwork, efficiency, and patient-centered care
Benefits & Resources for Providers:
Competitive compensation and benefits
Employer-funded retirement plans
Paid occurrence malpractice coverage
Paid parental leave
Epic EHR with provider-centered optimization and robust user support
AI-enabled documentation and workflow tools integrated into Epic to reduce administrative burden and support clinical decision-making at the point of care
Team based care models that support sustainable workloads, shared responsibility, and provider well-being
Life in Camden and Elgin, South Carolina (Midlands Region):
Camden and Elgin offer the charm of small-town living with convenient access to Columbia and the greater Midlands region. Known as South Carolina’s oldest inland city, Camden blends rich history, equestrian culture, and Southern hospitality with a relaxed lifestyle and strong sense of community, while nearby Elgin continues to grow as a vibrant, family-friendly suburb.
Residents enjoy beautiful outdoor spaces, locally owned restaurants and shops, excellent schools, and year-round recreational activities including boating, fishing, golf, and hiking. From the historic character of Camden to the expanding energy of Elgin, providers can find the ideal balance of lifestyle and opportunity within the Midlands.
With easy access to Columbia’s metropolitan amenities, both communities offer the best of peaceful living paired with proximity to a thriving healthcare market, making the region an attractive place to live, work, and build a career.
Additional Job Description
About MUSC:
South Carolina’s leading academic health system, MUSC Health, serves patients across the state through a growing network of hospitals, clinics, and specialty services. As the clinical enterprise of the Medical University of South Carolina, MUSC Health integrates academic medicine, research, and education with a strong commitment to patient care.
If you like working with energetic enthusiastic individuals, you will enjoy your career with us!
The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need.
Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: http://www.uscis.gov/e-verify/employees
See All 56 NP Jobs in Columbia
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Find NP Jobs in ColumbiaNP Job Market in Columbia
Who's Hiring
- Prisma Health24

- Medical University of South Carolina6

- Lexington Health4

- Prisma Health Urgent Care4P
- Optum2

Top Industries Hiring
- Healthcare & Medical Services31
- Consulting & Professional Services11
- Education3
NP Jobs in Columbia: Frequently Asked Questions
How do I get a np job in Columbia?
Focus your search on Columbia's largest healthcare anchors, including hospital-affiliated multispecialty groups, federally qualified health centers serving underserved Midlands communities, and the growing network of urgent care and retail health clinics along Harbison Boulevard and Two Notch Road. Candidates with experience in family medicine, psychiatric mental health, or acute care tend to move fastest in this market, and any existing familiarity with South Carolina Medicaid patient populations is a genuine advantage with local employers.
Which companies hire nps in Columbia?
Columbia np roles are posted by Prisma Health, Medical University of South Carolina, and Lexington Health and others right now, based on current listings on Migrate Mate as of July 2026. The local market is anchored by large academic medical systems, community health organizations, and an expanding footprint of independent and corporate-owned specialty clinics throughout the greater Richland County area.
Are there remote np jobs in Columbia?
Yes, though remote work is limited for nps since most roles require direct patient contact and on-site clinical presence. About 19% of np openings tied to Columbia are remote or hybrid as of July 2026, concentrated in telehealth triage, behavioral health, and care management roles. Columbia's growing telehealth infrastructure, supported by several regional health systems, makes those remote-eligible positions more available here than in smaller South Carolina markets.
How can I get a np job in Columbia with little or no experience?
The most realistic entry path in Columbia is through residency or fellowship programs affiliated with the Midlands health systems, which are designed specifically for new graduate nps and provide supervised clinical hours in high-volume settings. Entry-level candidates often find traction at federally qualified health centers and community clinics in the greater Columbia area, where patient volume is high and mentorship structures are built in. Highlighting any clinical rotations completed in South Carolina and any experience with underserved or complex populations will strengthen your application with local hiring managers.
Which industries hire the most nps in Columbia?
Most np openings in Columbia sit in Healthcare & Medical Services, Consulting & Professional Services, and Education, per current listings on Migrate Mate as of July 2026. Columbia's role as South Carolina's capital and home to a major university health system drives consistent demand across those sectors, with state government health programs and a growing behavioral health services network adding further depth to local hiring.
Related Jobs in South Carolina
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