Nurse Manager Jobs in Columbia, SC

Nurse Manager jobs in Columbia, South Carolina draw heavily from the city's large healthcare corridor anchored in the Midlands, with roles concentrated in the Five Points, Forest Acres, and Northeast Columbia areas. Acute care, long-term care, and outpatient clinic networks are among the most active sectors, and employers hiring right now include Prisma Health, US Department of Veterans Affairs, and PruittHealth. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles77
Top employerPrisma Health
Work type100% On-site
Top credentialManaged Registered Nurses (RNs)
Companies hiring6

Showing 5 of 77+ Nurse Manager jobs

Supervisory Assistant Nurse Manager-Gastroenterology Department
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Added 5d ago
Supervisory Assistant Nurse Manager-Gastroenterology Department
US Department of Veterans Affairs
Columbia, South Carolina
Allied Health
Healthcare Administration
Mental & Behavioral Health
Social Work & Counseling
$87k - $153k/yr
On-Site
Managed Registered Nurses (RNs)
10,000+

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Registered Nurse - Assistant Nurse Manager - Emergency Department
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Added 5d ago
Registered Nurse - Assistant Nurse Manager - Emergency Department
US Department of Veterans Affairs
Columbia, South Carolina
Allied Health
Healthcare Administration
Mental & Behavioral Health
Social Work & Counseling
$87k - $153k/yr
On-Site
Managed Registered Nurses (RNs)
10,000+

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Regional Manager Nurse Practitioner
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Added 1w ago
Regional Manager Nurse Practitioner
PruittHealth
Columbia, South Carolina
Business Development
Customer Success
Program Management
Project Management
CPR Certification
10,000+

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Registered Nurse (RN) - Case Manager
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Added 2w ago
Registered Nurse (RN) - Case Manager
Angels of Care Pediatric Home Health
Columbia, South Carolina
Healthcare Administration
Nursing
Patient Services & Wellbeing
1,001-5,000

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Assistant Nurse Manager (RN) - Level I General Surgery Operating Room, FT, Days
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Added 1mo ago
Assistant Nurse Manager (RN) - Level I General Surgery Operating Room, FT, Days
Prisma Health
Columbia, South Carolina
Customer Service
Customer Support
Hospitality & Guest Services
Managed Registered Nurses (RNs)
10,000+

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See All 77 Nurse Manager Jobs in Columbia

Find roles in Columbia that match your experience and apply in just a few clicks.

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Nurse Manager Job Market in Columbia

Who's Hiring

  • Prisma Health35
  • US Department of Veterans Affairs14
  • PruittHealth7
  • VIA Health Partners7
  • Your Health Organization7

Top Industries Hiring

  • Healthcare & Medical Services

Nurse Manager Jobs in Columbia: Frequently Asked Questions

How do I get a nurse manager job in Columbia?

Focus your search on Columbia's major healthcare corridors, particularly the Midlands medical complex, outpatient networks along Garners Ferry Road, and long-term care facilities in Northeast Columbia. Acute care systems, rehabilitation centers, and federally qualified health centers are among the most consistent hirers. Candidates who bring direct unit leadership experience, familiarity with Joint Commission standards, and a history of improving staff retention stand out in Columbia's competitive nursing management market.

Which companies hire nurse managers in Columbia?

Employers hiring nurse managers in Columbia right now include Prisma Health, US Department of Veterans Affairs, and PruittHealth, based on current listings on Migrate Mate as of October 2026. Columbia's hiring landscape skews toward large health systems, community hospitals, and multi-site outpatient groups tied to the Midlands regional healthcare network.

Are there remote nurse manager jobs in Columbia?

Yes, though remote availability is limited for nurse managers since most roles require on-site leadership of clinical teams. About 0% of nurse manager openings tied to Columbia are remote or hybrid as of October 2026, primarily covering administrative, utilization review, and care coordination management functions rather than direct floor or unit oversight.

How can I get a nurse manager job in Columbia with little or no experience?

The most realistic entry path in Columbia is moving into a charge nurse or assistant nurse manager role at one of the city's community hospitals or multi-site outpatient clinics, which regularly develop internal candidates for management. Long-term care facilities and federally qualified health centers in the Midlands tend to offer structured leadership tracks for RNs who demonstrate initiative. Building familiarity with quality improvement processes and staff scheduling software strengthens any application at the local level.

Which industries hire the most nurse managers in Columbia?

Columbia nurse manager roles concentrate in Healthcare & Medical Services, based on current listings on Migrate Mate as of October 2026. Columbia's position as the state capital and a regional medical hub for the Midlands means these sectors maintain steady demand for experienced clinical leaders year-round.

See All 77 Nurse Manager Jobs in Columbia

Find roles in Columbia that match your experience and apply in just a few clicks.

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