Nurse Manager Jobs in Columbia, SC

Nurse Manager jobs in Columbia, South Carolina draw heavily from the city's large healthcare corridor anchored in the Midlands, with roles concentrated in the Five Points, Forest Acres, and Northeast Columbia areas. Acute care, long-term care, and outpatient clinic networks are among the most active sectors, and employers hiring right now include Prisma Health, PruittHealth, and Lexington Health. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles21
Top employerPrisma Health
Work type89% On-site
Top credentialBachelor's
Companies hiring6

Showing 5 of 21+ Nurse Manager jobs

Your Health Organization
Hospice RN Nurse Case Manager
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Your Health Organization
Added 1w ago
Hospice RN Nurse Case Manager
Your Health Organization
Columbia, South Carolina
Caregiving & Elderly Support
Healthcare Administration
Nursing
Patient Services & Wellbeing
$80k - $110k/yr
1,001-5,000

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Prisma Health
Nurse Manager (NM) -Ambulatory, Urology and Colorectal Surgery, FT
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Prisma Health
Added 1w ago
Nurse Manager (NM) -Ambulatory, Urology and Colorectal Surgery, FT
Prisma Health
Columbia, South Carolina
Healthcare Administration
Human Resources
Nursing
Managed Registered Nurses (RNs)
10,000+

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Prisma Health
Nurse Manager (NM)-Ambulatory, Maternal Fetal Medicine, FT
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Prisma Health
Added 1w ago
Nurse Manager (NM)-Ambulatory, Maternal Fetal Medicine, FT
Prisma Health
Columbia, South Carolina
Healthcare Administration
Human Resources
Nursing
Managed Registered Nurses (RNs)
10,000+

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VIA Health Partners
Hospice Registered Nurse (RN) Case Manager
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VIA Health Partners
Added 1w ago
Hospice Registered Nurse (RN) Case Manager
VIA Health Partners
Columbia, South Carolina
Caregiving & Elderly Support
Healthcare Administration
Nursing
Patient Services & Wellbeing
CPR Certification
501-1,000

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PruittHealth
Licensed Practical Nurse- Unit Manager- Blythewood
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PruittHealth
Added 2w ago
Licensed Practical Nurse- Unit Manager- Blythewood
PruittHealth
Columbia, South Carolina
Healthcare Administration
Human Resources
Nursing
10,000+

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See All 21 Nurse Manager Jobs in Columbia

Find roles in Columbia that match your experience and apply in just a few clicks.

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Nurse Manager Job Market in Columbia

Who's Hiring

  • Prisma Health
    Prisma Health13
  • PruittHealth
    PruittHealth2
  • Lexington Health
    Lexington Health2
  • VIA Health Partners
    VIA Health Partners2
  • Your Health Organization
    Your Health Organization1

Top Industries Hiring

  • Healthcare & Medical Services
  • Consulting & Professional Services

Nurse Manager Jobs in Columbia: Frequently Asked Questions

How do I get a nurse manager job in Columbia?

Focus your search on Columbia's major healthcare corridors, particularly the Midlands medical complex, outpatient networks along Garners Ferry Road, and long-term care facilities in Northeast Columbia. Acute care systems, rehabilitation centers, and federally qualified health centers are among the most consistent hirers. Candidates who bring direct unit leadership experience, familiarity with Joint Commission standards, and a history of improving staff retention stand out in Columbia's competitive nursing management market.

Which companies hire nurse managers in Columbia?

Employers hiring nurse managers in Columbia right now include Prisma Health, PruittHealth, and Lexington Health, based on current listings on Migrate Mate as of July 2026. Columbia's hiring landscape skews toward large health systems, community hospitals, and multi-site outpatient groups tied to the Midlands regional healthcare network.

Are there remote nurse manager jobs in Columbia?

Yes, though remote availability is limited for nurse managers since most roles require on-site leadership of clinical teams. About 11% of nurse manager openings tied to Columbia are remote or hybrid as of July 2026, primarily covering administrative, utilization review, and care coordination management functions rather than direct floor or unit oversight.

How can I get a nurse manager job in Columbia with little or no experience?

The most realistic entry path in Columbia is moving into a charge nurse or assistant nurse manager role at one of the city's community hospitals or multi-site outpatient clinics, which regularly develop internal candidates for management. Long-term care facilities and federally qualified health centers in the Midlands tend to offer structured leadership tracks for RNs who demonstrate initiative. Building familiarity with quality improvement processes and staff scheduling software strengthens any application at the local level.

Which industries hire the most nurse managers in Columbia?

Columbia nurse manager roles concentrate in Healthcare & Medical Services and Consulting & Professional Services, based on current listings on Migrate Mate as of July 2026. Columbia's position as the state capital and a regional medical hub for the Midlands means these sectors maintain steady demand for experienced clinical leaders year-round.

See All 21 Nurse Manager Jobs in Columbia

Find roles in Columbia that match your experience and apply in just a few clicks.

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