Nurse Manager Jobs in South Carolina
Nurse Manager jobs in South Carolina are open across Columbia, Charleston, and Greenville and other South Carolina metros, with employers like Prisma Health, Medical University of South Carolina, and PruittHealth hiring at every experience level. Find a role that fits below and apply directly.
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INTRODUCTION
Job Description Summary
Entity
Medical University Hospital Authority (MUHA)
Worker Type
Employee
Worker Sub-Type
Regular
Cost Center
CC000521 CHS - Mother & Baby Unit (SJCH)
Pay Rate Type
Salary
Pay Grade
Health-31
Scheduled Weekly Hours
40
Work Shift
JOB DESCRIPTION
Provides clinical and administrative leadership support for a defined patient care area(s). Responsibilities include fostering a patient centered professional work environment through the implementation of the Theory of Human Caring, the nursing process, staff development and collaborative team interactions for the enhancement of the quality of patient care. Partners with the Nurse Manager to achieve goals to improve quality of care.
ADDITIONAL JOB DESCRIPTION
Education: Bachelor of Nursing (BSN) degree required. For positions located in Charleston, a Bachelor of Nursing (BSN) degree is required, and completion of Master of Nursing (MSN) or graduate degree in related field within four years.
Experience: A minimum of 3 years of nursing work experience required (2 years of nursing experience and 1 year of supervisory experience).
Licensure/Certification: Licensure as a registered nurse by the South Carolina Board of Nursing or compact state required. Current American Heart Association (AHA) Basic Life Support (BLS) certification or American Red Cross BLS for Healthcare Providers certification is required.
If you like working with energetic enthusiastic individuals, you will enjoy your career with us!
The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need.
Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: http://www.uscis.gov/e-verify/employees
LOCATION
Charleston, South Carolina
JOB TYPE
Full Time
See All 49 Nurse Manager Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find Nurse Manager JobsNurse Manager Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Nurse Manager Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring
- Prisma Health20

- Medical University of South Carolina14

- PruittHealth5

- Lexington Health4

- BAYADA Home Health Care1

Top Industries Hiring
- Healthcare & Medical Services43
- Consulting & Professional Services3
- Education3
What South Carolina Employers Look For
The qualifications that appear most often in nurse manager jobs across South Carolina.
- Active RN licensure with a bachelor of science in nursing (BSN) required
- Minimum two to five years of clinical nursing experience in the relevant specialty
- Demonstrated experience in staff supervision, scheduling, or charge nurse responsibilities
- Master of science in nursing (MSN) or nursing administration degree preferred or required
- Proficiency with electronic health record systems such as Epic or Cerner
- Basic Life Support (BLS) and Advanced Cardiac Life Support (ACLS) certifications required
Nurse Manager Jobs in South Carolina: Frequently Asked Questions
How many nurse manager jobs are there in South Carolina?
There are 49+ nurse manager openings in South Carolina on Migrate Mate as of June 2026, with the most roles in Columbia, Charleston, and Greenville. New positions post regularly as employers across South Carolina hire.
Which South Carolina cities have the most nurse manager jobs?
Columbia, Charleston, and Greenville have the most nurse manager openings in South Carolina right now, with additional roles spread across smaller metros statewide.
Which companies hire nurse managers in South Carolina?
Employers hiring nurse managers in South Carolina include Prisma Health, Medical University of South Carolina, and PruittHealth, based on current listings on Migrate Mate as of June 2026.
Are there remote nurse manager jobs in South Carolina?
Yes. About 2% of nurse manager openings tied to South Carolina are remote or hybrid as of June 2026. The rest are on-site roles based in South Carolina metros.
How do I apply for nurse manager jobs in South Carolina?
You can apply to nurse manager jobs in South Carolina directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred South Carolina location, then apply to each one that fits.
See All 49 Nurse Manager Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find Nurse Manager Jobs