Nurse Manager Jobs in South Carolina
Nurse manager jobs in South Carolina are concentrated in hospital systems, long-term care networks, and outpatient surgery centers, with consistent demand from entry-level charge nurse transitions through senior nursing leadership roles. Columbia, Greenville, and Charleston are the largest hiring markets, home to major systems like Prisma Health, Bon Secours, and MUSC Health. The most in-demand specialties are med-surg, critical care, and behavioral health. See the openings below and apply to the ones that match your experience.
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Showing 5 of 74+ Nurse Manager jobs
Inspire health. Serve with compassion. Be the difference.
Job Summary
In collaboration with the nurse manager, supervises staff and unit operations and provides direct patient care. Supervises care provided by staff to ensure the delivery of safe and quality patient care on the unit and to ensure appropriate standards of professional nursing practice are maintained in the clinical setting. Maintains high visibility to patients/families and staff on the unit, primarily on off-shifts, and resolves problems as needed. Performs a variety of administrative, human resource, payroll, quality improvement and unit coordination activities. Serves in direct patient care role greater than 50% of the time.Essential Functions
All team members are expected to be knowledgeable and compliant with Prisma Health's purpose: Inspire health. Serve with compassion. Be the difference.
Oversees a variety of patient care activities in a charge nurse capacity to ensure the delivery of safe and quality patient care on the unit/service. Activities include but are not limited to staff allocation and scheduling; patient assignments; rounds; investigation/resolution of patient care issues; coordination of admissions, discharges, and transfers; ensuring appropriate transitions of care between shifts; and interdepartmental coordination.
Provides direct patient care consistent with the charge nurse/clinical registered nurse job description accountabilities. Maintains all clinical competencies outlined.
Performs a variety of patient experience activities to ensure that patient experience expectations are met or exceeded. Activities include but are not limited to role modeling; staff mentoring/ coaching; patient rounds; service recovery; and problem resolution.
Assists with continuing staff development to include clinical problem solving and decision-making skills. Collaborates with clinical nurse educators to support new staff orientation and training. Maintains records/documentation pertaining to staff competencies, certification and/or licensure. Serves as a professional role model, coach and resource for employees.
Performs a variety of administrative and quality management activities to ensure that quality expectations and regulatory requirements are met. Ensures unit compliance with departmental, Prisma Health, safety, regulatory, environmental, and infection control standards. Maintains records/ documentation pertaining to regulatory/environmental standards, quality audits or other unit-related record-keeping requirements. Assists Nurse Manager in preparation of Joint Commission visits, etc.
In collaboration with the Nurse Manager, performs a variety of human resources activities including, but not limited to interviewing, hiring, evaluating, coaching, counseling, staff rounding and performance management of unit staff. May assist with Payroll processing.
Assists the Nurse Manager in maintaining unit budget by appropriate allocation and utilization of unit resources. Shares accountability with Nurse Manager for unit/department/organizational goal achievement.
Assists in planning, directing, and evaluating various short-term and long-term projects for the unit. Develops, submits, implements and evaluates performance objectives for self and unit. Works with health care team members on activities designed to improve patient care outcomes. Participates in Nursing and/or hospital committees and work groups as needed.
Performs other duties as assigned.
Supervisory/Management Responsibility
This is a supervisor job which may have direct supervision of team members which may include hire/termination authority, disciplinary authority, and performance management responsibilities. May have budget input or responsibilities. Job is not considered a member of management staff.
Minimum Requirements
Education - Bachelor's degree in Nursing
Experience - Two (2) years of RN experience in related area of nursing. Management/supervisory experience preferred.
In Lieu Of
In lieu of the BSN requirement above, a nursing diploma or an Associate's Degree in Nursing may be considered if the applicant signs a Memorandum of Understanding agreeing to enroll in an accredited BSN or MSN program within one year and obtain a BSN or MSN degree within four years.
Required Certifications, Registrations, Licenses
Holds a current RN compact/multistate license recognized by the NCSBN Compact State or is licensed to practice as an RN in the state the team member is working.
Certified in nursing specialty preferred.
Team members working in Critical Care Transport are required to have a valid driver’s license and an acceptable motor vehicle record, as defined by the Acceptable Motor Vehicle Record (MVR) Chart.
Knowledge, Skills and Abilities
NA
Work Shift
Night (United States of America)Location
Marshall Pickens HospitalFacility
Marshall I Pickens HospitalDepartment
Nursing Service Unit AShare your talent with us! Our vision is simple: to transform healthcare for the benefits of the communities we serve. The transformation of healthcare requires talented individuals in every role here at Prisma Health.
Inspire health. Serve with compassion. Be the difference.
Job Summary
In collaboration with the nurse manager, supervises staff and unit operations and provides direct patient care. Supervises care provided by staff to ensure the delivery of safe and quality patient care on the unit and to ensure appropriate standards of professional nursing practice are maintained in the clinical setting. Maintains high visibility to patients/families and staff on the unit, primarily on off-shifts, and resolves problems as needed. Performs a variety of administrative, human resource, payroll, quality improvement and unit coordination activities. Serves in direct patient care role greater than 50% of the time.Essential Functions
All team members are expected to be knowledgeable and compliant with Prisma Health's purpose: Inspire health. Serve with compassion. Be the difference.
Oversees a variety of patient care activities in a charge nurse capacity to ensure the delivery of safe and quality patient care on the unit/service. Activities include but are not limited to staff allocation and scheduling; patient assignments; rounds; investigation/resolution of patient care issues; coordination of admissions, discharges, and transfers; ensuring appropriate transitions of care between shifts; and interdepartmental coordination.
Provides direct patient care consistent with the charge nurse/clinical registered nurse job description accountabilities. Maintains all clinical competencies outlined.
Performs a variety of patient experience activities to ensure that patient experience expectations are met or exceeded. Activities include but are not limited to role modeling; staff mentoring/ coaching; patient rounds; service recovery; and problem resolution.
Assists with continuing staff development to include clinical problem solving and decision-making skills. Collaborates with clinical nurse educators to support new staff orientation and training. Maintains records/documentation pertaining to staff competencies, certification and/or licensure. Serves as a professional role model, coach and resource for employees.
Performs a variety of administrative and quality management activities to ensure that quality expectations and regulatory requirements are met. Ensures unit compliance with departmental, Prisma Health, safety, regulatory, environmental, and infection control standards. Maintains records/ documentation pertaining to regulatory/environmental standards, quality audits or other unit-related record-keeping requirements. Assists Nurse Manager in preparation of Joint Commission visits, etc.
In collaboration with the Nurse Manager, performs a variety of human resources activities including, but not limited to interviewing, hiring, evaluating, coaching, counseling, staff rounding and performance management of unit staff. May assist with Payroll processing.
Assists the Nurse Manager in maintaining unit budget by appropriate allocation and utilization of unit resources. Shares accountability with Nurse Manager for unit/department/organizational goal achievement.
Assists in planning, directing, and evaluating various short-term and long-term projects for the unit. Develops, submits, implements and evaluates performance objectives for self and unit. Works with health care team members on activities designed to improve patient care outcomes. Participates in Nursing and/or hospital committees and work groups as needed.
Performs other duties as assigned.
Supervisory/Management Responsibility
This is a supervisor job which may have direct supervision of team members which may include hire/termination authority, disciplinary authority, and performance management responsibilities. May have budget input or responsibilities. Job is not considered a member of management staff.
Minimum Requirements
Education - Bachelor's degree in Nursing
Experience - Two (2) years of RN experience in related area of nursing. Management/supervisory experience preferred.
In Lieu Of
In lieu of the BSN requirement above, a nursing diploma or an Associate's Degree in Nursing may be considered if the applicant signs a Memorandum of Understanding agreeing to enroll in an accredited BSN or MSN program within one year and obtain a BSN or MSN degree within four years.
Required Certifications, Registrations, Licenses
Holds a current RN compact/multistate license recognized by the NCSBN Compact State or is licensed to practice as an RN in the state the team member is working.
Certified in nursing specialty preferred.
Team members working in Critical Care Transport are required to have a valid driver’s license and an acceptable motor vehicle record, as defined by the Acceptable Motor Vehicle Record (MVR) Chart.
Knowledge, Skills and Abilities
NA
Work Shift
Night (United States of America)Location
Marshall Pickens HospitalFacility
Marshall I Pickens HospitalDepartment
Nursing Service Unit AShare your talent with us! Our vision is simple: to transform healthcare for the benefits of the communities we serve. The transformation of healthcare requires talented individuals in every role here at Prisma Health.
See All 74 Nurse Manager Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find Nurse Manager JobsNurse Manager Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Nurse Manager Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring
- Your Health Organization25
- Prisma Health11
- Bon Secours3
- PruittHealth3
- VIA Health Partners3
Top Industries Hiring
- Healthcare & Medical Services
- Insurance
What South Carolina Employers Look For
The qualifications that appear most often in nurse manager jobs across South Carolina.
- Active registered nurse license issued or recognized by the South Carolina Board of Nursing
- Bachelor of Science in Nursing required, with master's degree preferred for senior leadership roles
- Minimum of two to five years of clinical nursing experience in an acute care setting
- Prior charge nurse, team lead, or supervisory experience within a hospital or health system
- Nursing leadership certification such as NE-BC or CENP strongly preferred by most employers
- Demonstrated proficiency with electronic health records systems such as Epic or Cerner
Nurse Manager Jobs in South Carolina: Frequently Asked Questions
How do you become a nurse manager in South Carolina?
You become a nurse manager in South Carolina by first holding an active registered nurse license issued by the South Carolina Board of Nursing, which requires passing the NCLEX-RN exam. Most employers require a Bachelor of Science in Nursing at minimum, and many South Carolina health systems prefer candidates who hold a master's degree in nursing or healthcare administration. Clinical experience in a supervisory or charge nurse role is typically the most direct path into management.
Which companies hire nurse managers in South Carolina?
Employers hiring nurse managers in South Carolina right now include Your Health Organization, Prisma Health, and Bon Secours, based on current listings on Migrate Mate as of August 2026. South Carolina's largest health systems, anchored in Columbia, Greenville, and Charleston, drive a significant share of ongoing nurse manager demand across acute care, ambulatory, and specialty settings.
Which South Carolina cities have the most nurse manager jobs?
Greenville, Columbia, and Aiken have the highest concentration of nurse manager openings in South Carolina. Columbia leads as the state capital and home to major systems like Prisma Health, while Charleston's position as a regional academic medical center hub supports strong demand at MUSC Health and surrounding facilities, and Greenville's growing Upstate health corridor anchors activity in the northwestern part of the state.
Are there remote nurse manager jobs in South Carolina?
Yes, but they're rare. About 71% of nurse manager openings tied to South Carolina are remote or hybrid as of August 2026, reflecting the hands-on, floor-based nature of most nursing leadership roles. The portions of the job most likely to be performed remotely include administrative tasks, staff scheduling, compliance reporting, and virtual team meetings, particularly in larger multi-site health systems.
How can I get hired as a nurse manager in South Carolina with little or no experience?
The most realistic path is moving into a charge nurse or assistant nurse manager role first, which is how most South Carolina health systems develop internal leadership candidates. Prisma Health, Bon Secours, and MUSC Health all run nurse residency and leadership development programs that give clinical nurses structured exposure to management responsibilities. Earning a nursing leadership certification like NE-BC while still in a staff role signals readiness and gives candidates without formal management experience a measurable edge in South Carolina interviews.
Where can I find and apply to nurse manager jobs in South Carolina?
You can find and apply to nurse manager jobs in South Carolina on Migrate Mate, which lists current openings across the state. Search by city or specialty to see roles that match your background, then apply directly to the ones that fit your experience and schedule.
See All 74 Nurse Manager Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find Nurse Manager Jobs