Nurse Practitioner Jobs in San Diego, CA

Nurse practitioner jobs in San Diego are in strong demand, concentrated in Mission Valley, Kearny Mesa, and the Gaslamp Quarter medical corridor, across health systems, outpatient clinics, urgent care networks, and federally qualified health centers. Employers hiring right now include Rady Children's Hospital, UC San Diego Health, and Perlman Clinic. Find a role that fits below and apply directly.

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Overview

Open roles68
Top employerRady Children's Hospital
Work type70% On-site
Top credentialBLS Certification
Companies hiring39

Showing 5 of 68+ Nurse Practitioner jobs

Woundtech
Nurse Practitioner or Physician Assistant, Part Time Day Shift, San Diego, CA
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Woundtech
New 1m ago
Nurse Practitioner or Physician Assistant, Part Time Day Shift, San Diego, CA
Woundtech
San Diego, California
Business Development
Customer Success
Program Management
Project Management
On-Site
201-500

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One Medical
Family Nurse Practitioner or Physician Assistant
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One Medical
New 1m ago
Family Nurse Practitioner or Physician Assistant
One Medical
San Diego, California
Business Operations
Compensation & Benefits
Human Resources (HR) — Generalist
1,001-5,000

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Perlman Clinic
Physician Assistant / Nurse Practitioner - Primary Care
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Perlman Clinic
New 1m ago
Physician Assistant / Nurse Practitioner - Primary Care
Perlman Clinic
San Diego, California
Healthcare Administration
Patient Services & Wellbeing
Physicians
On-Site
201-500

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Perlman Clinic
Physician Assistant - Cardiology - Nurse Practitioner
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Perlman Clinic
New 1m ago
Physician Assistant - Cardiology - Nurse Practitioner
Perlman Clinic
San Diego, California
Healthcare Administration
Patient Services & Wellbeing
Physicians
On-Site
201-500

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Perlman Clinic
Dermatology Physician Assistant / Nurse Practitioner
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Perlman Clinic
New 1m ago
Dermatology Physician Assistant / Nurse Practitioner
Perlman Clinic
San Diego, California
Healthcare Administration
Patient Services & Wellbeing
Physicians
On-Site
201-500

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See All 68 Nurse Practitioner Jobs in San Diego

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Nurse Practitioner Job Market in San Diego

Who's Hiring

  • Rady Children's Hospital
    Rady Children's Hospital10
  • UC San Diego Health
    UC San Diego Health6
  • Perlman Clinic
    Perlman Clinic4
  • Spectrum Healthcare Resources
    Spectrum Healthcare Resources4
  • Sharp HealthCare
    Sharp HealthCare3

Top Industries Hiring

  • Healthcare & Medical Services22
  • Agriculture & Farming1

Nurse Practitioner Jobs in San Diego: Frequently Asked Questions

How do I get a nurse practitioner job in San Diego?

San Diego's hiring is driven by large health systems, military-affiliated medical facilities, and a dense network of community health centers serving the region's diverse population. Candidates with bilingual Spanish skills or experience in federally qualified health centers stand out locally. Focusing applications on Mission Valley medical campuses, the UCSD Health system footprint, and La Jolla's specialty clinics puts you in front of the highest volume of active openings.

Which companies hire nurse practitioners in San Diego?

Companies currently hiring nurse practitioners in San Diego include Rady Children's Hospital, UC San Diego Health, and Perlman Clinic, per current listings on Migrate Mate as of July 2026. San Diego's employer mix leans heavily toward large integrated health systems, county-run clinics, and military or VA-affiliated medical centers, reflecting the city's strong defense and public health presence.

Are there remote nurse practitioner jobs in San Diego?

Yes, though remote opportunities are limited by nature since most nurse practitioner roles involve direct patient care. About 30% of nurse practitioner openings tied to San Diego are remote or hybrid as of July 2026, concentrated in telehealth platforms and utilization review. Psychiatric and mental health nurse practitioners find the most remote-eligible positions in the San Diego market.

How can I get a nurse practitioner job in San Diego with little or no experience?

The most realistic entry path in San Diego is joining a federally qualified health center or a county Department of Health Services clinic, both of which regularly hire new graduates and offer structured onboarding. Naval Medical Center San Diego and VA San Diego Healthcare System also have residency and fellowship tracks designed for early-career NPs. Completing clinical rotations locally and building connections through UCSD or USD NP programs gives candidates a practical edge with San Diego hiring managers.

Which industries hire the most nurse practitioners in San Diego?

The sectors hiring the most nurse practitioners in San Diego are Healthcare & Medical Services and Agriculture & Farming, based on current listings on Migrate Mate as of July 2026. San Diego's large military population, concentration of biotech employers offering occupational health services, and extensive community health infrastructure across border-region neighborhoods all sustain consistent demand across those sectors.

See All 68 Nurse Practitioner Jobs in San Diego

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