Nurse Practitioner Jobs in St. Louis, MO

Nurse Practitioner jobs in St. Louis are in strong demand, concentrated in the Central West End, Cortex Innovation Community, and South City corridors across health systems, federally qualified health centers, and specialty clinics. Employers hiring right now include Washington University in St. Louis, SSM Health, and BJC HealthCare. See the openings below and apply to the ones that match your experience.

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Overview

Open roles108+
Top employerWashington University in St. Louis
Work type83% On-site
Top credentialBLS Certification
Companies hiring38

Showing 5 of 108+ Nurse Practitioner jobs

State of Missouri
Psychiatric Mental Health Nurse Practitioner-FTCN
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State of Missouri
New 1m ago
Psychiatric Mental Health Nurse Practitioner-FTCN
State of Missouri
St. Louis, Missouri
Allied Health
Healthcare Administration
Nursing

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State of Missouri
Psychiatric Mental Health Nurse Practitioner-FTCS
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State of Missouri
New 1m ago
Psychiatric Mental Health Nurse Practitioner-FTCS
State of Missouri
St. Louis, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing

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Comprehensive Rehab Consultants
Psychiatric Mental Health Nurse Practitioner (PMHNP)
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Comprehensive Rehab Consultants
New 1m ago
Psychiatric Mental Health Nurse Practitioner (PMHNP)
Comprehensive Rehab Consultants
St. Louis, Missouri
Healthcare Administration
Patient Services & Wellbeing
Social Work & Counseling
Master's degree in nursing
51-200

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C
Nurse Practitioner
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C
New 1m ago
Nurse Practitioner
Company
St. Louis, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
CPR Certification

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BJC HealthCare
Advanced Practice Provider - Dual Role: Pre-Op evaluations/Inpatient Post Op care
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BJC HealthCare
New 1m ago
Advanced Practice Provider - Dual Role: Pre-Op evaluations/Inpatient Post Op care
BJC HealthCare
St. Louis, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
Master's degree
10,000+

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Nurse Practitioner Job Market in St. Louis

Who's Hiring

  • Washington University in St. Louis
    Washington University in St. Louis22
  • SSM Health
    SSM Health16
  • BJC HealthCare
    BJC HealthCare14
  • Mercy
    Mercy13
  • Esse Health
    Esse Health3

Top Industries Hiring

  • Healthcare & Medical Services22
  • Education21
  • Technology & Software1
  • Consulting & Professional Services1

Nurse Practitioner Jobs in St. Louis: Frequently Asked Questions

How do I get a nurse practitioner job in St. Louis?

Focus your search on St. Louis's dominant hiring sectors: large academic health systems anchored in the Central West End, community health centers serving underserved neighborhoods in North and South City, and outpatient specialty practices throughout the county. Candidates with experience in primary care, urgent care, or psychiatric mental health tend to move quickly here. Familiarity with Missouri's full-practice authority environment and experience in underserved or rural outreach also stands out to local employers.

Which companies hire nurse practitioners in St. Louis?

Employers hiring nurse practitioners in St. Louis right now include Washington University in St. Louis, SSM Health, and BJC HealthCare, based on current listings on Migrate Mate as of July 2026. St. Louis hiring is led by major academic medical centers, regional health systems, and a growing network of outpatient and specialty clinic groups spread across the city and surrounding county.

Are there remote nurse practitioner jobs in St. Louis?

Yes, though remote roles are limited by nature since most nurse practitioner work requires direct patient contact. About 17% of nurse practitioner openings tied to St. Louis are remote or hybrid as of July 2026, with those roles concentrated in telehealth primary care, behavioral health, and care management. St. Louis-based insurers and regional telehealth networks are the most active sources of fully remote positions locally.

How can I get a nurse practitioner job in St. Louis with little or no experience?

The most realistic entry path in St. Louis is through new-graduate NP programs at large health systems, which offer structured orientation and preceptorship for clinicians transitioning from RN roles. Federally qualified health centers and community mental health agencies in St. Louis also hire new graduates more readily than private specialty practices. Completing clinical rotations with local employers during your NP program is one of the strongest indicators of hire, as many St. Louis sites extend offers to former students they already know.

Which industries hire the most nurse practitioners in St. Louis?

Most nurse practitioner openings in St. Louis sit in Healthcare & Medical Services, Education, and Technology & Software, per current listings on Migrate Mate as of July 2026. St. Louis's deep concentration of academic medical institutions, safety-net health centers, and expanding outpatient behavioral health networks drives consistent demand across those sectors throughout the year.

See All 108+ Nurse Practitioner Jobs in St. Louis

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