Nurse Practitioner Jobs in St. Louis, MO

Nurse Practitioner jobs in St. Louis are in strong demand, concentrated in the Central West End, Cortex Innovation Community, and South City corridors across health systems, federally qualified health centers, and specialty clinics. Employers hiring right now include Mercy, ChenMed, and BJC HealthCare. See the openings below and apply to the ones that match your experience.

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Overview

Open roles77
Top employerMercy
Work type48% Remote
Top credentialBLS Certification
Companies hiring10

Showing 5 of 77+ Nurse Practitioner jobs

TeamHealth
Advanced Practice Clinician In St. Louis, MO
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TeamHealth
Added 1d ago
Advanced Practice Clinician In St. Louis, MO
TeamHealth
St. Louis, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
10,000+

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BJC HealthCare
Advanced Practice Provider - Vascular Surgery, Days
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BJC HealthCare
Added 2d ago
Advanced Practice Provider - Vascular Surgery, Days
BJC HealthCare
St. Louis, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
$105k.8 - $159k.2/yr
Acute Care Nurse Practitioner Certification - Adult Gerontology
10,000+

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C
Wound Care Nurse Practitioner (Part-Time, 1099 Contractor)
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C
Added 2d ago
Wound Care Nurse Practitioner (Part-Time, 1099 Contractor)
CuraWound
St. Louis, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
$60 - $80/hr
On-Site

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CVS Health
Nurse Practitioner
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CVS Health
Added 4d ago
Nurse Practitioner
CVS Health
St. Louis, Missouri
Customer Service
Customer Support
Hospitality & Guest Services
$41.85 - $90.13/hr
Bachelor of Science
10,000+

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BJC HealthCare
Advanced Practice Provider - Vascular & Thoracic Surgery, Days
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BJC HealthCare
Added 5d ago
Advanced Practice Provider - Vascular & Thoracic Surgery, Days
BJC HealthCare
St. Louis, Missouri
Business Operations
Customer Service
Customer Success
$105k.8 - $159k.2/yr
Hybrid
Acute Care Nurse Practitioner Certification - Adult Gerontology
10,000+

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See All 77 Nurse Practitioner Jobs in St. Louis

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Nurse Practitioner Job Market in St. Louis

Who's Hiring

  • Mercy
    Mercy17
  • ChenMed
    ChenMed11
  • BJC HealthCare
    BJC HealthCare11
  • Advantmed
    Advantmed6
  • C
    CuraWound6

Nurse Practitioner Jobs in St. Louis: Frequently Asked Questions

How do I get a nurse practitioner job in St. Louis?

Focus your search on St. Louis's dominant hiring sectors: large academic health systems anchored in the Central West End, community health centers serving underserved neighborhoods in North and South City, and outpatient specialty practices throughout the county. Candidates with experience in primary care, urgent care, or psychiatric mental health tend to move quickly here. Familiarity with Missouri's full-practice authority environment and experience in underserved or rural outreach also stands out to local employers.

Which companies hire nurse practitioners in St. Louis?

Employers hiring nurse practitioners in St. Louis right now include Mercy, ChenMed, and BJC HealthCare, based on current listings on Migrate Mate as of August 2026. St. Louis hiring is led by major academic medical centers, regional health systems, and a growing network of outpatient and specialty clinic groups spread across the city and surrounding county.

Are there remote nurse practitioner jobs in St. Louis?

Yes, though remote roles are limited by nature since most nurse practitioner work requires direct patient contact. About 74% of nurse practitioner openings tied to St. Louis are remote or hybrid as of August 2026, with those roles concentrated in telehealth primary care, behavioral health, and care management. St. Louis-based insurers and regional telehealth networks are the most active sources of fully remote positions locally.

How can I get a nurse practitioner job in St. Louis with little or no experience?

The most realistic entry path in St. Louis is through new-graduate NP programs at large health systems, which offer structured orientation and preceptorship for clinicians transitioning from RN roles. Federally qualified health centers and community mental health agencies in St. Louis also hire new graduates more readily than private specialty practices. Completing clinical rotations with local employers during your NP program is one of the strongest indicators of hire, as many St. Louis sites extend offers to former students they already know.

See All 77 Nurse Practitioner Jobs in St. Louis

Find roles in St. Louis that match your experience and apply in just a few clicks.

Find Nurse Practitioner Jobs