Nurse Practitioner Jobs in Missouri
Nurse Practitioner jobs in Missouri are open across St. Louis, Columbia, and Springfield and other Missouri metros, with employers like Washington University in St. Louis, University of Missouri, and Mercy hiring at every experience level. Find a role that fits below and apply directly.
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At LifeStance Health, we believe in a truly healthy society where mental and physical healthcare are unified to make lives better. Our mission is to help people lead healthier, more fulfilling lives by improving access to trusted, affordable, and personalized mental healthcare. Everywhere. Every day. It’s a lofty goal; we know. But we make it happen with the best team in behavioral health.
Thank you for taking the time to explore a career with us. As the fastest growing behavioral health practice group in the country, now is the perfect time to join our clinical team!
We are actively seeking a talented Psychiatric Mental Health Nurse Practitioner (PMHNP) in the Town and Country, MO area who is passionate about patient care and committed to excellence.
What we offer our Nurse Practitioners:
- Flexible schedules - create your own schedule and have full autonomy over your caseload
- Competitive compensation model based on productivity - up to $206K - $240K+, and annual cash bonus incentive
- Sign-on bonus!
- 100% outpatient – no nights, weekends, or hospital calls
- Hybrid options: Telemedicine & in-person care
- Comprehensive benefits: W2 position, health, dental, vision, 401k w/ match, parental leave & more
- Modern offices, digital tools & full admin support
- Collegial team & strong work/life balance
Nurse Practitioners are a critical part of our clinical team. We’re seeking Nurse Practitioners that are:
- Licensed in MO as an APRN with PMHNP Board Certification by the ANCC.
- Active MO DEA.
- 1+ year of PMHNP Experience post training.
- Hybrid role
Please apply now or contact me directly:
Katie Hanley
Director, Practice Development
LifeStance Health, Inc.
(e) Katie.Hanley@LifeStance.com
About LifeStance Health
LifeStance is a national provider of mental healthcare services focused on evidenced-based, medically driven treatment services for children, adolescents and adults suffering from a variety of mental health issues in an outpatient care setting, both in-person at its clinics nationwide and through its digital health telemedicine offering. The company employs psychiatrists, psychologists, psychiatric nurse practitioners, and licensed therapists throughout the US.
LifeStance Health is an equal opportunity employer. We celebrate diversity and are fully committed to creating an inclusive work environment for all our employees.
Our values:
Belonging: We cultivate a space where everyone can show up as their authentic self.
Empathy: We seek out diverse perspectives and listen to learn without judgment.
Courage: We are all accountable for doing the right thing - even when it's hard - because we know it's worth it.
One Team: We realize our full potential when we work together towards our shared purpose.
If you elect to interact with us via our website, please only use www.lifestance.com or www.careers.lifestance.com. Additionally, our recruiters utilize email addresses with the @lifestance.com domain. Other websites and domains are not affiliated with LifeStance Health and may represent threats to your data security.
LifeStance Health complies with federal and state disability laws and makes reasonable accommodations for applicants and employees with disabilities. If reasonable accommodation is needed to participate in the job application or interview process, to perform essential job functions, and/or to receive other benefits and privileges of employment, please contact our Human Resources Team at ADA@lifestance.com or by calling +1-800-308-0994.
Please note: This contact is intended solely for accommodation requests. Inquiries regarding applications, resumes and applicant status should not be sent to this email address as they will not be reviewed or responded to. To apply for a position, please use our official careers page.
See All 114+ Nurse Practitioner Jobs in Missouri
Find roles in Missouri that match your experience and apply in just a few clicks.
Find Nurse Practitioner JobsNurse Practitioner Jobs by City in Missouri
Where Missouri roles are concentrated, by current openings.
Nurse Practitioner Job Market in Missouri
A snapshot from current Missouri openings, updated as new roles post.
Who's Hiring
- Washington University in St. Louis27

- University of Missouri16

- Mercy13

- SSM Health9

- CoxHealth8

Top Industries Hiring
- Healthcare & Medical Services63
- Education47
- Consulting & Professional Services7
- Insurance2
What Missouri Employers Look For
The qualifications that appear most often in nurse practitioner jobs across Missouri.
- Current NP certification from ANCC or AANP in a recognized specialty
- Active, unencumbered state license as an Advanced Practice Registered Nurse
- Master of Science in Nursing or Doctor of Nursing Practice degree
- Current BLS and ACLS certification from the American Heart Association
- Minimum one to two years of clinical NP or RN experience in a relevant setting
- Experience with electronic health record systems such as Epic or Cerner
Nurse Practitioner Jobs in Missouri: Frequently Asked Questions
How many nurse practitioner jobs are there in Missouri?
There are 114+ nurse practitioner openings in Missouri on Migrate Mate as of June 2026, with the most roles in St. Louis, Columbia, and Springfield. New positions post regularly as employers across Missouri hire.
How much do nurse practitioners make in Missouri?
Nurse practitioners in Missouri earn a median of about $129,930 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $100,650 for the lowest 10% to over $162,060 for the top 10%. Pay rises with experience, specialty, and employer.
Which Missouri cities have the most nurse practitioner jobs?
St. Louis, Columbia, and Springfield have the most nurse practitioner openings in Missouri right now, with additional roles spread across smaller metros statewide.
Which companies hire nurse practitioners in Missouri?
Employers hiring nurse practitioners in Missouri include Washington University in St. Louis, University of Missouri, and Mercy, based on current listings on Migrate Mate as of June 2026.
Are there remote nurse practitioner jobs in Missouri?
Yes. About 3% of nurse practitioner openings tied to Missouri are remote or hybrid as of June 2026. The rest are on-site roles based in Missouri metros.
How do I apply for nurse practitioner jobs in Missouri?
You can apply to nurse practitioner jobs in Missouri directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred Missouri location, then apply to each one that fits.
See All 114+ Nurse Practitioner Jobs in Missouri
Find roles in Missouri that match your experience and apply in just a few clicks.
Find Nurse Practitioner Jobs