Operations Lead Jobs in San Francisco, CA

Operations Lead jobs in San Francisco are concentrated across tech, healthcare, and logistics, with employers clustered in SoMa, the Financial District, and Mission Bay. Companies currently hiring include OpenAI, SERVAL, and Notion. See the openings below and apply to the ones that match your experience.

Find Operations Lead Jobs

Overview

Open roles279+
Top employerOpenAI
Work type50% On-site
Top credentialMaster's degree in business administration
Companies hiring46

Showing 5 of 279+ Operations Lead jobs

Anthropic
Operations Lead, Investor Relations
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Anthropic
Added 1d ago
Operations Lead, Investor Relations
Anthropic
San Francisco, California
AI (Artificial Intelligence)
Data Science
$200k - $265k/yr
Hybrid
Bachelor's degree
51-200

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G
Security Operations Lead
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G
Added 1d ago
Security Operations Lead
Goodfire
San Francisco, California
Customer Service
Customer Support
$200k - $350k/yr
On-Site

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OpenAI
Creative Operations Lead, Business Marketing
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OpenAI
Added 1d ago
Creative Operations Lead, Business Marketing
OpenAI
San Francisco, California
Business Operations
Product Management
Project Management
$287k - $318k/yr
Hybrid
51-200

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Meta
Sales Strategy and Planning Operations Lead, GBG Americas
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Meta
Added 1d ago
Sales Strategy and Planning Operations Lead, GBG Americas
Meta
San Francisco, California
Enterprise Sales
Inside Sales
Sales
$107k - $149k/yr
Master's degree in business administration
10,000+

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Perplexity
Strategic Business Operations Lead, API
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Perplexity
Added 2d ago
Strategic Business Operations Lead, API
Perplexity
San Francisco, California
Business Operations
Program Management
Project Management
$170k - $220k/yr
Hybrid

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See All 279+ Operations Lead Jobs in San Francisco

Find roles in San Francisco that match your experience and apply in just a few clicks.

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Operations Lead Job Market in San Francisco

Who's Hiring

  • OpenAI
    OpenAI38
  • SERVAL
    SERVAL14
  • Notion
    Notion10
  • Anthropic
    Anthropic10
  • Amazon Web Services
    Amazon Web Services10

Top Industries Hiring

  • Technology & Software34
  • Science & Research10
  • Staffing & Recruiting5

Operations Lead Jobs in San Francisco: Frequently Asked Questions

How do I get a operations lead job in San Francisco?

Focus your search on San Francisco's dominant sectors: enterprise technology companies in SoMa, biotech and life sciences firms in Mission Bay, and financial services employers in the Financial District. Candidates with direct experience managing cross-functional teams or scaling operational workflows stand out here. Familiarity with high-growth startup environments is a genuine edge in this market, where many employers move quickly and expect candidates to lead with minimal ramp-up time.

Which companies hire operations leads in San Francisco?

Companies currently hiring operations leads in San Francisco include OpenAI, SERVAL, and Notion, per current listings on Migrate Mate as of September 2026. San Francisco's employer mix skews heavily toward technology platforms, venture-backed startups, and large healthcare systems, all of which maintain dedicated operations functions across multiple teams.

Are there remote operations lead jobs in San Francisco?

Yes, though availability depends heavily on the role type: operational leads tied to physical sites, warehouses, or in-person teams are almost always on-site, while analytically focused or program-management-oriented roles are far more likely to be remote. About 50% of operations lead openings tied to San Francisco are remote or hybrid as of September 2026, with the most flexibility found in tech-sector roles based in SoMa and the Financial District.

How can I get a operations lead job in San Francisco with little or no experience?

The most realistic entry path is through coordinator or associate operations roles at San Francisco's mid-size tech companies or healthcare organizations, where internal mobility into lead positions is common. Look for operations associate titles at Mission Bay biotech firms or SoMa startups, where lean teams give junior staff broad exposure. Strong project management fundamentals, familiarity with tools like Asana or Notion, and demonstrated ownership of a process improvement project all help a candidate stand out locally.

Which industries hire the most operations leads in San Francisco?

The sectors hiring the most operations leads in San Francisco are Technology & Software, Science & Research, and Staffing & Recruiting, based on current listings on Migrate Mate as of September 2026. San Francisco's concentration of technology headquarters, life sciences campuses in Mission Bay, and major financial institutions in the Financial District creates consistent, high-volume demand for operations leadership across those industries.

See All 279+ Operations Lead Jobs in San Francisco

Find roles in San Francisco that match your experience and apply in just a few clicks.

Find Operations Lead Jobs