Operations Lead Jobs in San Francisco, CA

Operations Lead jobs in San Francisco are concentrated across tech, healthcare, and logistics, with employers clustered in SoMa, the Financial District, and Mission Bay. Companies currently hiring include OpenAI, Notion, and Uber. See the openings below and apply to the ones that match your experience.

Find Operations Lead Jobs

Overview

Open roles57
Top employerOpenAI
Work type47% On-site
Companies hiring43

Showing 5 of 57+ Operations Lead jobs

Anthropic
Research Operations Lead
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Anthropic
Added 1d ago
Research Operations Lead
Anthropic
San Francisco, California
Procurement & Supply Chain
Project & Program Management
Procurement & Purchasing
Logistics & Fleet Management
$200k/yr
Hybrid
Bachelor's

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Anthropic
Research Operations Lead, Biology
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Anthropic
Added 1d ago
Research Operations Lead, Biology
Anthropic
San Francisco, California
Account Management
Customer Success
Sales
$150k - $200k/yr
Hybrid
Bachelor's degree
51-200

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C
RN Clinical Operations & Strategy Lead
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C
Added 1d ago
RN Clinical Operations & Strategy Lead
CuraFi
San Francisco, California
Clinical Support
Healthcare Administration
Medical Coding & Billing
$140k - $160k/yr
Hybrid
Managed Registered Nurses (RNs)

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LiveRamp
CS Strategy & Operations Lead
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LiveRamp
Added 2d ago
CS Strategy & Operations Lead
LiveRamp
San Francisco, California
Business Strategy
Corporate Development & M&A
Executive Leadership & C-Suite
$132k - $171k/yr
Remote (US)
1,001-5,000

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Relevance AI
Revenue Operations Lead
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Relevance AI
Added 1w ago
Revenue Operations Lead
Relevance AI
San Francisco, California
Business Operations
Revenue Operations & Enablement
Sales
Hybrid

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See All 57 Operations Lead Jobs in San Francisco

Find roles in San Francisco that match your experience and apply in just a few clicks.

Find Operations Lead Jobs

Operations Lead Job Market in San Francisco

Who's Hiring

OpenAI
OpenAI8 open roles
Notion
Notion3 open roles
Uber
Uber2 open roles

Top Industries Hiring

  • Technology & Software14
  • Science & Research7
  • Consumer Goods1
  • Healthcare & Medical Services1

Operations Lead Jobs in San Francisco: Frequently Asked Questions

How do I get a operations lead job in San Francisco?

Focus your search on San Francisco's dominant sectors: enterprise technology companies in SoMa, biotech and life sciences firms in Mission Bay, and financial services employers in the Financial District. Candidates with direct experience managing cross-functional teams or scaling operational workflows stand out here. Familiarity with high-growth startup environments is a genuine edge in this market, where many employers move quickly and expect candidates to lead with minimal ramp-up time.

Which companies hire operations leads in San Francisco?

Companies currently hiring operations leads in San Francisco include OpenAI, Notion, and Uber, per current listings on Migrate Mate as of July 2026. San Francisco's employer mix skews heavily toward technology platforms, venture-backed startups, and large healthcare systems, all of which maintain dedicated operations functions across multiple teams.

Are there remote operations lead jobs in San Francisco?

Yes, though availability depends heavily on the role type: operational leads tied to physical sites, warehouses, or in-person teams are almost always on-site, while analytically focused or program-management-oriented roles are far more likely to be remote. About 53% of operations lead openings tied to San Francisco are remote or hybrid as of July 2026, with the most flexibility found in tech-sector roles based in SoMa and the Financial District.

How can I get a operations lead job in San Francisco with little or no experience?

The most realistic entry path is through coordinator or associate operations roles at San Francisco's mid-size tech companies or healthcare organizations, where internal mobility into lead positions is common. Look for operations associate titles at Mission Bay biotech firms or SoMa startups, where lean teams give junior staff broad exposure. Strong project management fundamentals, familiarity with tools like Asana or Notion, and demonstrated ownership of a process improvement project all help a candidate stand out locally.

Which industries hire the most operations leads in San Francisco?

The sectors hiring the most operations leads in San Francisco are Technology & Software, Science & Research, and Consumer Goods, based on current listings on Migrate Mate as of July 2026. San Francisco's concentration of technology headquarters, life sciences campuses in Mission Bay, and major financial institutions in the Financial District creates consistent, high-volume demand for operations leadership across those industries.

See All 57 Operations Lead Jobs in San Francisco

Find roles in San Francisco that match your experience and apply in just a few clicks.

Find Operations Lead Jobs