Operations Lead Jobs in San Francisco, CA

Operations Lead jobs in San Francisco are concentrated across tech, healthcare, and logistics, with employers clustered in SoMa, the Financial District, and Mission Bay. Companies currently hiring include OpenAI, Amazon Web Services, and Rippling. See the openings below and apply to the ones that match your experience.

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Overview

Open roles321+
Top employerOpenAI
Work type39% Hybrid
Top credentialBachelor's degree
Companies hiring50

Showing 5 of 321+ Operations Lead jobs

Trusted Access Lead, Critical Harm Operations
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Added 3d ago
Trusted Access Lead, Critical Harm Operations
OpenAI
San Francisco, California
Customer Service
Customer Service & Support
Customer Support
$252k - $335k/yr
51-200

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Founding Operations Lead
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Added 5d ago
Founding Operations Lead
INFINITE
San Francisco, California
Program Management
Project & Program Management
Project Management

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Core Operations Lead, Community & Culture
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Added 5d ago
Core Operations Lead, Community & Culture
OpenAI
San Francisco, California
Accounting
Business Operations
$266k - $295k/yr
Hybrid
51-200

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Strategy and Operations Lead, Creative Partnerships
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Added 5d ago
Strategy and Operations Lead, Creative Partnerships
OpenAI
San Francisco, California
Accounting
Business Operations
$333k - $370k/yr
Hybrid
51-200

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Revenue Operations Lead, Central
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Added 6d ago
Revenue Operations Lead, Central
COGENT SECURITY
San Francisco, California
Business Development
Customer Success
Project Management
Remote (US)

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See All 321+ Operations Lead Jobs in San Francisco

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Operations Lead Job Market in San Francisco

Who's Hiring

  • OpenAI41
  • Amazon Web Services18
  • Rippling14
  • SERVAL9
  • WHSmith9

Top Industries Hiring

  • Science & Research
  • Technology & Software
  • Staffing & Recruiting

Operations Lead Jobs in San Francisco: Frequently Asked Questions

How do I get a operations lead job in San Francisco?

Focus your search on San Francisco's dominant sectors: enterprise technology companies in SoMa, biotech and life sciences firms in Mission Bay, and financial services employers in the Financial District. Candidates with direct experience managing cross-functional teams or scaling operational workflows stand out here. Familiarity with high-growth startup environments is a genuine edge in this market, where many employers move quickly and expect candidates to lead with minimal ramp-up time.

Which companies hire operations leads in San Francisco?

Companies currently hiring operations leads in San Francisco include OpenAI, Amazon Web Services, and Rippling, per current listings on Migrate Mate as of November 2026. San Francisco's employer mix skews heavily toward technology platforms, venture-backed startups, and large healthcare systems, all of which maintain dedicated operations functions across multiple teams.

Are there remote operations lead jobs in San Francisco?

Yes, though availability depends heavily on the role type: operational leads tied to physical sites, warehouses, or in-person teams are almost always on-site, while analytically focused or program-management-oriented roles are far more likely to be remote. About 74% of operations lead openings tied to San Francisco are remote or hybrid as of November 2026, with the most flexibility found in tech-sector roles based in SoMa and the Financial District.

How can I get a operations lead job in San Francisco with little or no experience?

The most realistic entry path is through coordinator or associate operations roles at San Francisco's mid-size tech companies or healthcare organizations, where internal mobility into lead positions is common. Look for operations associate titles at Mission Bay biotech firms or SoMa startups, where lean teams give junior staff broad exposure. Strong project management fundamentals, familiarity with tools like Asana or Notion, and demonstrated ownership of a process improvement project all help a candidate stand out locally.

Which industries hire the most operations leads in San Francisco?

The sectors hiring the most operations leads in San Francisco are Science & Research, Technology & Software, and Staffing & Recruiting, based on current listings on Migrate Mate as of November 2026. San Francisco's concentration of technology headquarters, life sciences campuses in Mission Bay, and major financial institutions in the Financial District creates consistent, high-volume demand for operations leadership across those industries.

See All 321+ Operations Lead Jobs in San Francisco

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